Radiomics Approaches for the Prediction of Pathological Complete Response after Neoadjuvant Treatment in Locally Advanced Rectal Cancer: Ready for Prime Time?
Cancers
Bourbonne, Vincent V; Schick, Ulrike U; Pradier, Olivier O; Visvikis, Dimitris D; Metges, Jean-Philippe JP; Badic, Bogdan B
Genomics of asthma, allergy and chronic rhinosinusitis: novel concepts and relevance in airway mucosa.
Clinical And Translational Allergy
Laulajainen-Hongisto, Anu A; Lyly, Annina A; Hanif, Tanzeela T; Dhaygude, Kishor K; Kankainen, Matti M; Renkonen, Risto R; Donner, Kati K; Mattila, Pirkko P; Jartti, Tuomas T; Bousquet, Jean J; Kauppi, Paula P; Toppila-Salmi, Sanna S
Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.
Scientific Reports
Tsui, Nancy B Y NBY; Cheng, Gregory G; Chung, Teresa T; Lam, Christopher W K CWK; Yee, Anita A; Chung, Peter K C PKC; Kwan, Tsz-Ki TK; Ko, Elaine E; He, Daihai D; Wong, Wing-Tak WT; Lau, Johnson Y N JYN; Lau, Lok Ting LT; Fok, Manson M
The role of SMAD3 in the genetic predisposition to papillary thyroid carcinoma.
Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
Wang, Yanqiang Y; He, Huiling H; Liyanarachchi, Sandya S; Genutis, Luke K LK; Li, Wei W; Yu, Lianbo L; Phay, John E JE; Shen, Rulong R; Brock, Pamela P; de la Chapelle, Albert A
A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.
The European Respiratory Journal
Yan, Qi Q; Brehm, John J; Pino-Yanes, Maria M; Forno, Erick E; Lin, Jerome J; Oh, Sam S SS; Acosta-Perez, Edna E; Laurie, Cathy C CC; Cloutier, Michelle M MM; Raby, Benjamin A BA; Stilp, Adrienne M AM; Sofer, Tamar T; Hu, Donglei D; Huntsman, Scott S; Eng, Celeste S CS; Conomos, Matthew P MP; Rastogi, Deepa D; Rice, Kenneth K; Canino, Glorisa G; Chen, Wei W; Barr, R Graham RG; Burchard, Esteban G EG; Celedón, Juan C JC
Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers.
The Journal Of Allergy And Clinical Immunology
DeVries, Avery A; Wlasiuk, Gabriela G; Miller, Susan J SJ; Bosco, Anthony A; Stern, Debra A DA; Lohman, I Carla IC; Rothers, Janet J; Jones, Anya C AC; Nicodemus-Johnson, Jessie J; Vasquez, Monica M MM; Curtin, John A JA; Simpson, Angela A; Custovic, Adnan A; Jackson, Daniel J DJ; Gern, James E JE; Lemanske, Robert F RF; Guerra, Stefano S; Wright, Anne L AL; Ober, Carole C; Halonen, Marilyn M; Vercelli, Donata D
The genetic and epigenetic landscapes of the epithelium in asthma.
Respiratory Research
Moheimani, Fatemeh F; Hsu, Alan C-Y AC; Reid, Andrew T AT; Williams, Teresa T; Kicic, Anthony A; Stick, Stephen M SM; Hansbro, Philip M PM; Wark, Peter A B PA; Knight, Darryl A DA
Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.
Allergy
Nieuwenhuis, M A MA; Siedlinski, M M; van den Berge, M M; Granell, R R; Li, X X; Niens, M M; van der Vlies, P P; Altmüller, J J; Nürnberg, P P; Kerkhof, M M; van Schayck, O C OC; Riemersma, R A RA; van der Molen, T T; de Monchy, J G JG; Bossé, Y Y; Sandford, A A; Bruijnzeel-Koomen, C A CA; Gerth van Wijk, R R; Ten Hacken, N H NH; Timens, W W; Boezen, H M HM; Henderson, J J; Kabesch, M M; Vonk, J M JM; Postma, D S DS; Koppelman, G H GH
Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients.
Oncotarget
Dreussi, Eva E; Pucciarelli, Salvatore S; De Paoli, Antonino A; Polesel, Jerry J; Canzonieri, Vincenzo V; Agostini, Marco M; Friso, Maria Luisa ML; Belluco, Claudio C; Buonadonna, Angela A; Lonardi, Sara S; Zanusso, Chiara C; De Mattia, Elena E; Toffoli, Giuseppe G; Cecchin, Erika E
eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes.
Allergy
Li, X X; Hastie, A T AT; Hawkins, G A GA; Moore, W C WC; Ampleford, E J EJ; Milosevic, J J; Li, H H; Busse, W W WW; Erzurum, S C SC; Kaminski, N N; Wenzel, S E SE; Meyers, D A DA; Bleecker, E R ER
Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants.
The Journal Of Allergy And Clinical Immunology
van der Valk, Ralf Jp RJ; Duijts, Liesbeth L; Timpson, Nicolas J NJ; Salam, Muhammad T MT; Standl, Marie M; Curtin, John A JA; Genuneit, Jon J; Kerhof, Marjan M; Kreiner-Møller, Eskil E; Cáceres, Alejandro A; Gref, Anna A; Liang, Liming L LL; Taal, H Rob HR; Bouzigon, Emmanuelle E; Demenais, Florence F; Nadif, Rachel R; Ober, Carole C; Thompson, Emma E EE; Estrada, Karol K; Hofman, Albert A; Uitterlinden, André G AG; van Duijn, Cornélia C; Rivadeneira, Fernando F; Li, Xia X; Eckel, Sandrah P SP; Berhane, Kiros K; Gauderman, W James WJ; Granell, Raquel R; Evans, David M DM; St Pourcain, Beate B; McArdle, Wendy W; Kemp, John P JP; Smith, George Davey GD; Tiesler, Carla Mt CM; Flexeder, Claudia C; Simpson, Angela A; Murray, Clare S CS; Fuchs, Oliver O; Postma, Dirkje S DS; Bønnelykke, Klaus K; Torrent, Maties M; Andersson, Martin M; Sleiman, Patrick P; Hakonarson, Hakon H; Cookson, William O WO; Moffatt, Miriam F MF; Paternoster, Lavinia L; Melén, Erik E; Sunyer, Jordi J; Bisgaard, Hans H; Koppelman, Gerard H GH; Ege, Markus M; Custovic, Adnan A; Heinrich, Joachim J; Gilliland, Frank D FD; Henderson, Alexander J AJ; Jaddoe, Vincent Wv VW; de Jongste, Johan C JC; ,
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
Human Molecular Genetics
Weidinger, Stephan S; Willis-Owen, Saffron A G SA; Kamatani, Yoichiro Y; Baurecht, Hansjörg H; Morar, Nilesh N; Liang, Liming L; Edser, Pauline P; Street, Teresa T; Rodriguez, Elke E; O'Regan, Grainne M GM; Beattie, Paula P; Fölster-Holst, Regina R; Franke, Andre A; Novak, Natalija N; Fahy, Caoimhe M CM; Winge, Mårten C G MC; Kabesch, Michael M; Illig, Thomas T; Heath, Simon S; Söderhäll, Cilla C; Melén, Erik E; Pershagen, Göran G; Kere, Juha J; Bradley, Maria M; Lieden, Agne A; Nordenskjold, Magnus M; Harper, John I JI; McLean, W H Irwin WH; Brown, Sara J SJ; Cookson, William O C WO; Lathrop, G Mark GM; Irvine, Alan D AD; Moffatt, Miriam F MF
HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.
Clinical And Experimental Allergy : Journal Of The British Society For Allergy And Clinical Immunology
Lasky-Su, J J; Himes, B E BE; Raby, B A BA; Klanderman, B J BJ; Sylvia, J Senter JS; Lange, C C; Melen, E E; Martinez, F D FD; Israel, E E; Gauderman, J J; Gilliland, F F; Sleiman, P P; Hakonarson, H H; Celedón, J C JC; Soto-Quiros, M M; Avila, L L; Lima, J J JJ; Irvin, C G CG; Peters, S P SP; Boushey, H H; Chinchilli, V M VM; Mauger, D D; Tantisira, K K; Weiss, S T ST; ,
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.
Plos One
Ramasamy, Adaikalavan A; Kuokkanen, Mikko M; Vedantam, Sailaja S; Gajdos, Zofia K ZK; Couto Alves, Alexessander A; Lyon, Helen N HN; Ferreira, Manuel A R MA; Strachan, David P DP; Zhao, Jing Hua JH; Abramson, Michael J MJ; Brown, Matthew A MA; Coin, Lachlan L; Dharmage, Shyamali C SC; Duffy, David L DL; Haahtela, Tari T; Heath, Andrew C AC; Janson, Christer C; Kähönen, Mika M; Khaw, Kay-Tee KT; Laitinen, Jaana J; Le Souef, Peter P; Lehtimäki, Terho T; , ; Madden, Pamela A F PA; Marks, Guy B GB; Martin, Nicholas G NG; Matheson, Melanie C MC; Palmer, Cameron D CD; Palotie, Aarno A; Pouta, Anneli A; Robertson, Colin F CF; Viikari, Jorma J; Widen, Elisabeth E; Wjst, Matthias M; Jarvis, Deborah L DL; Montgomery, Grant W GW; Thompson, Philip J PJ; Wareham, Nick N; Eriksson, Johan J; Jousilahti, Pekka P; Laitinen, Tarja T; Pekkanen, Juha J; Raitakari, Olli T OT; O'Connor, George T GT; Salomaa, Veikko V; Jarvelin, Marjo-Riitta MR; Hirschhorn, Joel N JN
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature
, ; , ; Sawcer, Stephen S; Hellenthal, Garrett G; Pirinen, Matti M; Spencer, Chris C A CC; Patsopoulos, Nikolaos A NA; Moutsianas, Loukas L; Dilthey, Alexander A; Su, Zhan Z; Freeman, Colin C; Hunt, Sarah E SE; Edkins, Sarah S; Gray, Emma E; Booth, David R DR; Potter, Simon C SC; Goris, An A; Band, Gavin G; Oturai, Annette Bang AB; Strange, Amy A; Saarela, Janna J; Bellenguez, Céline C; Fontaine, Bertrand B; Gillman, Matthew M; Hemmer, Bernhard B; Gwilliam, Rhian R; Zipp, Frauke F; Jayakumar, Alagurevathi A; Martin, Roland R; Leslie, Stephen S; Hawkins, Stanley S; Giannoulatou, Eleni E; D'alfonso, Sandra S; Blackburn, Hannah H; Martinelli Boneschi, Filippo F; Liddle, Jennifer J; Harbo, Hanne F HF; Perez, Marc L ML; Spurkland, Anne A; Waller, Matthew J MJ; Mycko, Marcin P MP; Ricketts, Michelle M; Comabella, Manuel M; Hammond, Naomi N; Kockum, Ingrid I; McCann, Owen T OT; Ban, Maria M; Whittaker, Pamela P; Kemppinen, Anu A; Weston, Paul P; Hawkins, Clive C; Widaa, Sara S; Zajicek, John J; Dronov, Serge S; Robertson, Neil N; Bumpstead, Suzannah J SJ; Barcellos, Lisa F LF; Ravindrarajah, Rathi R; Abraham, Roby R; Alfredsson, Lars L; Ardlie, Kristin K; Aubin, Cristin C; Baker, Amie A; Baker, Katharine K; Baranzini, Sergio E SE; Bergamaschi, Laura L; Bergamaschi, Roberto R; Bernstein, Allan A; Berthele, Achim A; Boggild, Mike M; Bradfield, Jonathan P JP; Brassat, David D; Broadley, Simon A SA; Buck, Dorothea D; Butzkueven, Helmut H; Capra, Ruggero R; Carroll, William M WM; Cavalla, Paola P; Celius, Elisabeth G EG; Cepok, Sabine S; Chiavacci, Rosetta R; Clerget-Darpoux, Françoise F; Clysters, Katleen K; Comi, Giancarlo G; Cossburn, Mark M; Cournu-Rebeix, Isabelle I; Cox, Mathew B MB; Cozen, Wendy W; Cree, Bruce A C BA; Cross, Anne H AH; Cusi, Daniele D; Daly, Mark J MJ; Davis, Emma E; de Bakker, Paul I W PI; Debouverie, Marc M; D'hooghe, Marie Beatrice MB; Dixon, Katherine K; Dobosi, Rita R; Dubois, Bénédicte B; Ellinghaus, David D; Elovaara, Irina I; Esposito, Federica F; Fontenille, Claire C; Foote, Simon S; Franke, Andre A; Galimberti, Daniela D; Ghezzi, Angelo A; Glessner, Joseph J; Gomez, Refujia R; Gout, Olivier O; Graham, Colin C; Grant, Struan F A SF; Guerini, Franca Rosa FR; Hakonarson, Hakon H; Hall, Per P; Hamsten, Anders A; Hartung, Hans-Peter HP; Heard, Rob N RN; Heath, Simon S; Hobart, Jeremy J; Hoshi, Muna M; Infante-Duarte, Carmen C; Ingram, Gillian G; Ingram, Wendy W; Islam, Talat T; Jagodic, Maja M; Kabesch, Michael M; Kermode, Allan G AG; Kilpatrick, Trevor J TJ; Kim, Cecilia C; Klopp, Norman N; Koivisto, Keijo K; Larsson, Malin M; Lathrop, Mark M; Lechner-Scott, Jeannette S JS; Leone, Maurizio A MA; Leppä, Virpi V; Liljedahl, Ulrika U; Bomfim, Izaura Lima IL; Lincoln, Robin R RR; Link, Jenny J; Liu, Jianjun J; Lorentzen, Aslaug R AR; Lupoli, Sara S; Macciardi, Fabio F; Mack, Thomas T; Marriott, Mark M; Martinelli, Vittorio V; Mason, Deborah D; McCauley, Jacob L JL; Mentch, Frank F; Mero, Inger-Lise IL; Mihalova, Tania T; Montalban, Xavier X; Mottershead, John J; Myhr, Kjell-Morten KM; Naldi, Paola P; Ollier, William W; Page, Alison A; Palotie, Aarno A; Pelletier, Jean J; Piccio, Laura L; Pickersgill, Trevor T; Piehl, Fredrik F; Pobywajlo, Susan S; Quach, Hong L HL; Ramsay, Patricia P PP; Reunanen, Mauri M; Reynolds, Richard R; Rioux, John D JD; Rodegher, Mariaemma M; Roesner, Sabine S; Rubio, Justin P JP; Rückert, Ina-Maria IM; Salvetti, Marco M; Salvi, Erika E; Santaniello, Adam A; Schaefer, Catherine A CA; Schreiber, Stefan S; Schulze, Christian C; Scott, Rodney J RJ; Sellebjerg, Finn F; Selmaj, Krzysztof W KW; Sexton, David D; Shen, Ling L; Simms-Acuna, Brigid B; Skidmore, Sheila S; Sleiman, Patrick M A PM; Smestad, Cathrine C; Sørensen, Per Soelberg PS; Søndergaard, Helle Bach HB; Stankovich, Jim J; Strange, Richard C RC; Sulonen, Anna-Maija AM; Sundqvist, Emilie E; Syvänen, Ann-Christine AC; Taddeo, Francesca F; Taylor, Bruce B; Blackwell, Jenefer M JM; Tienari, Pentti P; Bramon, Elvira E; Tourbah, Ayman A; Brown, Matthew A MA; Tronczynska, Ewa E; Casas, Juan P JP; Tubridy, Niall N; Corvin, Aiden A; Vickery, Jane J; Jankowski, Janusz J; Villoslada, Pablo P; Markus, Hugh S HS; Wang, Kai K; Mathew, Christopher G CG; Wason, James J; Palmer, Colin N A CN; Wichmann, H-Erich HE; Plomin, Robert R; Willoughby, Ernest E; Rautanen, Anna A; Winkelmann, Juliane J; Wittig, Michael M; Trembath, Richard C RC; Yaouanq, Jacqueline J; Viswanathan, Ananth C AC; Zhang, Haitao H; Wood, Nicholas W NW; Zuvich, Rebecca R; Deloukas, Panos P; Langford, Cordelia C; Duncanson, Audrey A; Oksenberg, Jorge R JR; Pericak-Vance, Margaret A MA; Haines, Jonathan L JL; Olsson, Tomas T; Hillert, Jan J; Ivinson, Adrian J AJ; De Jager, Philip L PL; Peltonen, Leena L; Stewart, Graeme J GJ; Hafler, David A DA; Hauser, Stephen L SL; McVean, Gil G; Donnelly, Peter P; Compston, Alastair A
A large-scale, consortium-based genomewide association study of asthma.
The New England Journal Of Medicine
Moffatt, Miriam F MF; Gut, Ivo G IG; Demenais, Florence F; Strachan, David P DP; Bouzigon, Emmanuelle E; Heath, Simon S; von Mutius, Erika E; Farrall, Martin M; Lathrop, Mark M; Cookson, William O C M WOCM; ,