Genome-wide Association Studies of Retinal Vessel Tortuosity Identify Numerous Novel Loci Revealing Genes and Pathways Associated With Ocular and Cardiometabolic Diseases.
Ophthalmology Science
Tomasoni, Mattia M; Beyeler, Michael Johannes MJ; Vela, Sofia Ortin SO; Mounier, Ninon N; Porcu, Eleonora E; Corre, Tanguy T; Krefl, Daniel D; Button, Alexander Luke AL; Abouzeid, Hana H; Lazaros, Konstantinidis K; Bochud, Murielle M; Schlingemann, Reinier R; Bergin, Ciara C; Bergmann, Sven S
Kiani, Aysha Karim AK; Bonetti, Gabriele G; Donato, Kevin K; Kaftalli, Jurgen J; Herbst, Karen L KL; Stuppia, Liborio L; Fioretti, Francesco F; Nodari, Savina S; Perrone, Marco M; Chiurazzi, Pietro P; Bellinato, Francesco F; Gisondi, Paolo P; Bertelli, Matteo M
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes.
Bmc Medical Genomics
Poppenberg, Kerry E KE; Tutino, Vincent M VM; Tarbell, Evan E; Jarvis, James N JN
Pleiotropic Locus 15q24.1 Reveals a Gender-Specific Association with Neovascular but Not Atrophic Age-Related Macular Degeneration (AMD).
Cells
Kiel, Christina C; Strunz, Tobias T; International Amd Genomics Consortium Project Manager Susan Blanton Iamdgc, ; Grassmann, Felix F; Weber, Bernhard H F BHF
Exploration of CYP21A2 and CYP17A1 polymorphisms and preeclampsia risk among Chinese Han population: a large-scale case-control study based on 5021 subjects.
Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci.
Genome Medicine
Li, Tianlu T; Ortiz-Fernández, Lourdes L; Andrés-León, Eduardo E; Ciudad, Laura L; Javierre, Biola M BM; López-Isac, Elena E; Guillén-Del-Castillo, Alfredo A; Simeón-Aznar, Carmen Pilar CP; Ballestar, Esteban E; Martin, Javier J
Identifying Interactions between Dietary Sodium, Potassium, Sodium-Potassium Ratios, and FGF5 rs16998073 Variants and Their Associated Risk for Hypertension in Korean Adults.
Nutrients
Jeong, Hyeyun H; Jin, Hyun-Seok HS; Kim, Sung-Soo SS; Shin, Dayeon D
Comparative and Functional Genomic Resource for Mechanistic Studies of Human Blood Pressure-Associated Single Nucleotide Polymorphisms.
Hypertension (Dallas, Tex. : 1979)
Mishra, Manoj K MK; Liang, Eugene Y EY; Geurts, Aron M AM; Auer, Paul W L PWL; Liu, Pengyuan P; Rao, Sridhar S; Greene, Andrew S AS; Liang, Mingyu M; Liu, Yong Y
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.
Nature Communications
López-Isac, Elena E; Acosta-Herrera, Marialbert M; Kerick, Martin M; Assassi, Shervin S; Satpathy, Ansuman T AT; Granja, Jeffrey J; Mumbach, Maxwell R MR; Beretta, Lorenzo L; Simeón, Carmen P CP; Carreira, Patricia P; Ortego-Centeno, Norberto N; Castellvi, Ivan I; Bossini-Castillo, Lara L; Carmona, F David FD; Orozco, Gisela G; Hunzelmann, Nicolas N; Distler, Jörg H W JHW; Franke, Andre A; Lunardi, Claudio C; Moroncini, Gianluca G; Gabrielli, Armando A; de Vries-Bouwstra, Jeska J; Wijmenga, Cisca C; Koeleman, Bobby P C BPC; Nordin, Annika A; Padyukov, Leonid L; Hoffmann-Vold, Anna-Maria AM; Lie, Benedicte B; , ; Proudman, Susanna S; Stevens, Wendy W; Nikpour, Mandana M; , ; Vyse, Timothy T; Herrick, Ariane L AL; Worthington, Jane J; Denton, Christopher P CP; Allanore, Yannick Y; Brown, Matthew A MA; Radstake, Timothy R D J TRDJ; Fonseca, Carmen C; Chang, Howard Y HY; Mayes, Maureen D MD; Martin, Javier J
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
Molecular Genetics & Genomic Medicine
Lule, Swaib A SA; Mentzer, Alexander J AJ; Namara, Benigna B; Muwenzi, Allan G AG; Nassanga, Beatrice B; Kizito, Dennison D; Akurut, Helen H; Lubyayi, Lawrence L; Tumusiime, Josephine J; Zziwa, Christopher C; Akello, Florence F; Gurdasani, Deept D; Sandhu, Manjinder M; Smeeth, Liam L; Elliott, Alison M AM; Webb, Emily L EL
Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations.
Journal Of Personalized Medicine
Halladay, Jacqueline R JR; Lenhart, Kaitlin C KC; Robasky, Kimberly K; Jones, Wendell W; Homan, Wayne F WF; Cummings, Doyle M DM; Cené, Crystal W CW; Hinderliter, Alan L AL; Miller, Cassandra L CL; Donahue, Katrina E KE; Garcia, Beverly A BA; Keyserling, Thomas C TC; Ammerman, Alice S AS; Patterson, Cam C; DeWalt, Darren A DA; Johnston, Larry F LF; Willis, Monte S MS; Schisler, Jonathan C JC
Parental and offspring contribution of genetic markers of adult blood pressure in early life: The FAMILY study.
Plos One
Robiou-du-Pont, Sébastien S; Anand, Sonia S SS; Morrison, Katherine M KM; McDonald, Sarah D SD; Atkinson, Stephanie A SA; Teo, Koon K KK; Meyre, David D
Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.
Scientific Reports
Sofer, Tamar T; Wong, Quenna Q; Hartwig, Fernando P FP; Taylor, Kent K; Warren, Helen R HR; Evangelou, Evangelos E; Cabrera, Claudia P CP; Levy, Daniel D; Kramer, Holly H; Lange, Leslie A LA; Horta, Bernardo L BL; , ; Kerr, Kathleen F KF; Reiner, Alex P AP; Franceschini, Nora N
Hypertension Susceptibility Loci are Associated with Anthracycline-related Cardiotoxicity in Long-term Childhood Cancer Survivors.
Scientific Reports
Hildebrandt, Michelle A T MAT; Reyes, Monica M; Wu, Xifeng X; Pu, Xia X; Thompson, Kara A KA; Ma, Jianzhong J; Landstrom, Andrew P AP; Morrison, Alanna C AC; Ater, Joann L JL