Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.
Nature Communications
Ji, Xuemei X; Bossé, Yohan Y; Landi, Maria Teresa MT; Gui, Jiang J; Xiao, Xiangjun X; Qian, David D; Joubert, Philippe P; Lamontagne, Maxime M; Li, Yafang Y; Gorlov, Ivan I; de Biasi, Mariella M; Han, Younghun Y; Gorlova, Olga O; Hung, Rayjean J RJ; Wu, Xifeng X; McKay, James J; Zong, Xuchen X; Carreras-Torres, Robert R; Christiani, David C DC; Caporaso, Neil N; Johansson, Mattias M; Liu, Geoffrey G; Bojesen, Stig E SE; Le Marchand, Loic L; Albanes, Demetrios D; Bickeböller, Heike H; Aldrich, Melinda C MC; Bush, William S WS; Tardon, Adonina A; Rennert, Gad G; Chen, Chu C; Teare, M Dawn MD; Field, John K JK; Kiemeney, Lambertus A LA; Lazarus, Philip P; Haugen, Aage A; Lam, Stephen S; Schabath, Matthew B MB; Andrew, Angeline S AS; Shen, Hongbing H; Hong, Yun-Chul YC; Yuan, Jian-Min JM; Bertazzi, Pier A PA; Pesatori, Angela C AC; Ye, Yuanqing Y; Diao, Nancy N; Su, Li L; Zhang, Ruyang R; Brhane, Yonathan Y; Leighl, Natasha N; Johansen, Jakob S JS; Mellemgaard, Anders A; Saliba, Walid W; Haiman, Christopher C; Wilkens, Lynne L; Fernandez-Somoano, Ana A; Fernandez-Tardon, Guillermo G; van der Heijden, Erik H F M EHFM; Kim, Jin Hee JH; Dai, Juncheng J; Hu, Zhibin Z; Davies, Michael P A MPA; Marcus, Michael W MW; Brunnström, Hans H; Manjer, Jonas J; Melander, Olle O; Muller, David C DC; Overvad, Kim K; Trichopoulou, Antonia A; Tumino, Rosario R; Doherty, Jennifer J; Goodman, Gary E GE; Cox, Angela A; Taylor, Fiona F; Woll, Penella P; Brüske, Irene I; Manz, Judith J; Muley, Thomas T; Risch, Angela A; Rosenberger, Albert A; Grankvist, Kjell K; Johansson, Mikael M; Shepherd, Frances F; Tsao, Ming-Sound MS; Arnold, Susanne M SM; Haura, Eric B EB; Bolca, Ciprian C; Holcatova, Ivana I; Janout, Vladimir V; Kontic, Milica M; Lissowska, Jolanta J; Mukeria, Anush A; Ognjanovic, Simona S; Orlowski, Tadeusz M TM; Scelo, Ghislaine G; Swiatkowska, Beata B; Zaridze, David D; Bakke, Per P; Skaug, Vidar V; Zienolddiny, Shanbeh S; Duell, Eric J EJ; Butler, Lesley M LM; Koh, Woon-Puay WP; Gao, Yu-Tang YT; Houlston, Richard R; McLaughlin, John J; Stevens, Victoria V; Nickle, David C DC; Obeidat, Ma'en M; Timens, Wim W; Zhu, Bin B; Song, Lei L; Artigas, María Soler MS; Tobin, Martin D MD; Wain, Louise V LV; Gu, Fangyi F; Byun, Jinyoung J; Kamal, Ahsan A; Zhu, Dakai D; Tyndale, Rachel F RF; Wei, Wei-Qi WQ; Chanock, Stephen S; Brennan, Paul P; Amos, Christopher I CI
Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.
Nature Communications
Shi, Jianxin J; Marconett, Crystal N CN; Duan, Jubao J; Hyland, Paula L PL; Li, Peng P; Wang, Zhaoming Z; Wheeler, William W; Zhou, Beiyun B; Campan, Mihaela M; Lee, Diane S DS; Huang, Jing J; Zhou, Weiyin W; Triche, Tim T; Amundadottir, Laufey L; Warner, Andrew A; Hutchinson, Amy A; Chen, Po-Han PH; Chung, Brian S I BS; Pesatori, Angela C AC; Consonni, Dario D; Bertazzi, Pier Alberto PA; Bergen, Andrew W AW; Freedman, Mathew M; Siegmund, Kimberly D KD; Berman, Benjamin P BP; Borok, Zea Z; Chatterjee, Nilanjan N; Tucker, Margaret A MA; Caporaso, Neil E NE; Chanock, Stephen J SJ; Laird-Offringa, Ite A IA; Landi, Maria Teresa MT
Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
Human Molecular Genetics
Timofeeva, Maria N MN; Hung, Rayjean J RJ; Rafnar, Thorunn T; Christiani, David C DC; Field, John K JK; Bickeböller, Heike H; Risch, Angela A; McKay, James D JD; Wang, Yufei Y; Dai, Juncheng J; Gaborieau, Valerie V; McLaughlin, John J; Brenner, Darren D; Narod, Steven A SA; Caporaso, Neil E NE; Albanes, Demetrius D; Thun, Michael M; Eisen, Timothy T; Wichmann, H-Erich HE; Rosenberger, Albert A; Han, Younghun Y; Chen, Wei W; Zhu, Dakai D; Spitz, Margaret M; Wu, Xifeng X; Pande, Mala M; Zhao, Yang Y; Zaridze, David D; Szeszenia-Dabrowska, Neonilia N; Lissowska, Jolanta J; Rudnai, Peter P; Fabianova, Eleonora E; Mates, Dana D; Bencko, Vladimir V; Foretova, Lenka L; Janout, Vladimir V; Krokan, Hans E HE; Gabrielsen, Maiken Elvestad ME; Skorpen, Frank F; Vatten, Lars L; Njølstad, Inger I; Chen, Chu C; Goodman, Gary G; Lathrop, Mark M; Benhamou, Simone S; Vooder, Tõnu T; Välk, Kristjan K; Nelis, Mari M; Metspalu, Andres A; Raji, Olaide O; Chen, Ying Y; Gosney, John J; Liloglou, Triantafillos T; Muley, Thomas T; Dienemann, Hendrik H; Thorleifsson, Gudmar G; Shen, Hongbing H; Stefansson, Kari K; Brennan, Paul P; Amos, Christopher I CI; Houlston, Richard R; Landi, Maria Teresa MT; ,
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.
Genetic Epidemiology
Chen, Li-Shiun LS; Saccone, Nancy L NL; Culverhouse, Robert C RC; Bracci, Paige M PM; Chen, Chien-Hsiun CH; Dueker, Nicole N; Han, Younghun Y; Huang, Hongyan H; Jin, Guangfu G; Kohno, Takashi T; Ma, Jennie Z JZ; Przybeck, Thomas R TR; Sanders, Alan R AR; Smith, Jennifer A JA; Sung, Yun Ju YJ; Wenzlaff, Angie S AS; Wu, Chen C; Yoon, Dankyu D; Chen, Ying-Ting YT; Cheng, Yu-Ching YC; Cho, Yoon Shin YS; David, Sean P SP; Duan, Jubao J; Eaton, Charles B CB; Furberg, Helena H; Goate, Alison M AM; Gu, Dongfeng D; Hansen, Helen M HM; Hartz, Sarah S; Hu, Zhibin Z; Kim, Young Jin YJ; Kittner, Steven J SJ; Levinson, Douglas F DF; Mosley, Thomas H TH; Payne, Thomas J TJ; Rao, D C DC; Rice, John P JP; Rice, Treva K TK; Schwantes-An, Tae-Hwi TH; Shete, Sanjay S SS; Shi, Jianxin J; Spitz, Margaret R MR; Sun, Yan V YV; Tsai, Fuu-Jen FJ; Wang, Jen C JC; Wrensch, Margaret R MR; Xian, Hong H; Gejman, Pablo V PV; He, Jiang J; Hunt, Steven C SC; Kardia, Sharon L SL; Li, Ming D MD; Lin, Dongxin D; Mitchell, Braxton D BD; Park, Taesung T; Schwartz, Ann G AG; Shen, Hongbing H; Wiencke, John K JK; Wu, Jer-Yuarn JY; Yokota, Jun J; Amos, Christopher I CI; Bierut, Laura J LJ
Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials.
Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
King, David P DP; Paciga, Sara S; Pickering, Eve E; Benowitz, Neal L NL; Bierut, Laura J LJ; Conti, David V DV; Kaprio, Jaakko J; Lerman, Caryn C; Park, Peter W PW
Genetics of sputum gene expression in chronic obstructive pulmonary disease.
Plos One
Qiu, Weiliang W; Cho, Michael H MH; Riley, John H JH; Anderson, Wayne H WH; Singh, Dave D; Bakke, Per P; Gulsvik, Amund A; Litonjua, Augusto A AA; Lomas, David A DA; Crapo, James D JD; Beaty, Terri H TH; Celli, Bartolome R BR; Rennard, Stephen S; Tal-Singer, Ruth R; Fox, Steven M SM; Silverman, Edwin K EK; Hersh, Craig P CP; ,
Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.
Thorax
Brehm, John M JM; Hagiwara, Koichi K; Tesfaigzi, Yohannes Y; Bruse, Shannon S; Mariani, Thomas J TJ; Bhattacharya, Soumyaroop S; Boutaoui, Nadia N; Ziniti, John P JP; Soto-Quiros, Manuel E ME; Avila, Lydiana L; Cho, Michael H MH; Himes, Blanca B; Litonjua, Augusto A AA; Jacobson, Francine F; Bakke, Per P; Gulsvik, Amund A; Anderson, Wayne H WH; Lomas, David A DA; Forno, Erick E; Datta, Soma S; Silverman, Edwin K EK; Celedón, Juan C JC
Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study.
Carcinogenesis
Gago-Dominguez, Manuela M; Jiang, Xuejuan X; Conti, David V DV; Castelao, Jose Esteban JE; Stern, Mariana C MC; Cortessis, Victoria K VK; Pike, Malcolm C MC; Xiang, Yong-Bing YB; Gao, Yu-Tang YT; Yuan, Jian-Min JM; Van Den Berg, David J DJ
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
Plos Genetics
Saccone, Nancy L NL; Culverhouse, Robert C RC; Schwantes-An, Tae-Hwi TH; Cannon, Dale S DS; Chen, Xiangning X; Cichon, Sven S; Giegling, Ina I; Han, Shizhong S; Han, Younghun Y; Keskitalo-Vuokko, Kaisu K; Kong, Xiangyang X; Landi, Maria Teresa MT; Ma, Jennie Z JZ; Short, Susan E SE; Stephens, Sarah H SH; Stevens, Victoria L VL; Sun, Lingwei L; Wang, Yufei Y; Wenzlaff, Angela S AS; Aggen, Steven H SH; Breslau, Naomi N; Broderick, Peter P; Chatterjee, Nilanjan N; Chen, Jingchun J; Heath, Andrew C AC; Heliövaara, Markku M; Hoft, Nicole R NR; Hunter, David J DJ; Jensen, Majken K MK; Martin, Nicholas G NG; Montgomery, Grant W GW; Niu, Tianhua T; Payne, Thomas J TJ; Peltonen, Leena L; Pergadia, Michele L ML; Rice, John P JP; Sherva, Richard R; Spitz, Margaret R MR; Sun, Juzhong J; Wang, Jen C JC; Weiss, Robert B RB; Wheeler, William W; Witt, Stephanie H SH; Yang, Bao-Zhu BZ; Caporaso, Neil E NE; Ehringer, Marissa A MA; Eisen, Tim T; Gapstur, Susan M SM; Gelernter, Joel J; Houlston, Richard R; Kaprio, Jaakko J; Kendler, Kenneth S KS; Kraft, Peter P; Leppert, Mark F MF; Li, Ming D MD; Madden, Pamela A F PA; Nöthen, Markus M MM; Pillai, Sreekumar S; Rietschel, Marcella M; Rujescu, Dan D; Schwartz, Ann A; Amos, Christopher I CI; Bierut, Laura J LJ
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
Nature Genetics
Thorgeirsson, Thorgeir E TE; Gudbjartsson, Daniel F DF; Surakka, Ida I; Vink, Jacqueline M JM; Amin, Najaf N; Geller, Frank F; Sulem, Patrick P; Rafnar, Thorunn T; Esko, Tõnu T; Walter, Stefan S; Gieger, Christian C; Rawal, Rajesh R; Mangino, Massimo M; Prokopenko, Inga I; Mägi, Reedik R; Keskitalo, Kaisu K; Gudjonsdottir, Iris H IH; Gretarsdottir, Solveig S; Stefansson, Hreinn H; Thompson, John R JR; Aulchenko, Yurii S YS; Nelis, Mari M; Aben, Katja K KK; den Heijer, Martin M; Dirksen, Asger A; Ashraf, Haseem H; Soranzo, Nicole N; Valdes, Ana M AM; Steves, Claire C; Uitterlinden, André G AG; Hofman, Albert A; Tönjes, Anke A; Kovacs, Peter P; Hottenga, Jouke Jan JJ; Willemsen, Gonneke G; Vogelzangs, Nicole N; Döring, Angela A; Dahmen, Norbert N; Nitz, Barbara B; Pergadia, Michele L ML; Saez, Berta B; De Diego, Veronica V; Lezcano, Victoria V; Garcia-Prats, Maria D MD; Ripatti, Samuli S; Perola, Markus M; Kettunen, Johannes J; Hartikainen, Anna-Liisa AL; Pouta, Anneli A; Laitinen, Jaana J; Isohanni, Matti M; Huei-Yi, Shen S; Allen, Maxine M; Krestyaninova, Maria M; Hall, Alistair S AS; Jones, Gregory T GT; van Rij, Andre M AM; Mueller, Thomas T; Dieplinger, Benjamin B; Haltmayer, Meinhard M; Jonsson, Steinn S; Matthiasson, Stefan E SE; Oskarsson, Hogni H; Tyrfingsson, Thorarinn T; Kiemeney, Lambertus A LA; Mayordomo, Jose I JI; Lindholt, Jes S JS; Pedersen, Jesper Holst JH; Franklin, Wilbur A WA; Wolf, Holly H; Montgomery, Grant W GW; Heath, Andrew C AC; Martin, Nicholas G NG; Madden, Pamela A F PA; Giegling, Ina I; Rujescu, Dan D; Järvelin, Marjo-Riitta MR; Salomaa, Veikko V; Stumvoll, Michael M; Spector, Tim D TD; Wichmann, H-Erich HE; Metspalu, Andres A; Samani, Nilesh J NJ; Penninx, Brenda W BW; Oostra, Ben A BA; Boomsma, Dorret I DI; Tiemeier, Henning H; van Duijn, Cornelia M CM; Kaprio, Jaakko J; Gulcher, Jeffrey R JR; , ; McCarthy, Mark I MI; Peltonen, Leena L; Thorsteinsdottir, Unnur U; Stefansson, Kari K
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
Cancer Research
Saccone, Nancy L NL; Wang, Jen C JC; Breslau, Naomi N; Johnson, Eric O EO; Hatsukami, Dorothy D; Saccone, Scott F SF; Grucza, Richard A RA; Sun, Lingwei L; Duan, Weimin W; Budde, John J; Culverhouse, Robert C RC; Fox, Louis L; Hinrichs, Anthony L AL; Steinbach, Joseph Henry JH; Wu, Meng M; Rice, John P JP; Goate, Alison M AM; Bierut, Laura J LJ