CHRNA3 c.1390-1247G>A

Variant ID: 15-78890321-C-T

NM_000743.4(CHRNA3):c.1390-1247G>A

This variant was identified in 19 publications

View GRCh38 version.




Publications:


Genetic Variants in Smoking-Related Genes in Two Smoking Cessation Programs: A Cross-Sectional Study.

International Journal Of Environmental Research And Public Health
Pérez-Rubio, Gloria G; López-Flores, Luis Alberto LA; Cupertino, Ana Paula AP; Cartujano-Barrera, Francisco F; Reynales-Shigematsu, Luz Myriam LM; Ramírez, Mariana M; Ellerbeck, Edward F EF; Rodríguez-Bolaños, Rosibel R; Falfan-Valencia, Ramcés R
Publication Date: 2021-06-19

Variant appearance in text: rs6495307
PubMed Link: 34205269
Variant Present in the following documents:
  • Main text
  • ijerph-18-06597.pdf
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Data on genotype frequency for SNPs associated to age of smoking onset and successful smoking cessation treatment.

Data In Brief
Pérez-Rubio, Gloria G; López-Flores, Luis Alberto LA; Ramírez-Venegas, Alejandra A; Sansores, Raúl H RH; Falfán-Valencia, Ramcés R
Publication Date: 2019-06

Variant appearance in text: rs6495307
PubMed Link: 31061854
Variant Present in the following documents:
  • Main text
  • main.pdf
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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs6495307
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
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Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population.

Translational Psychiatry
Liu, Qiang Q; Han, Haijun H; Wang, Maiqiu M; Yao, Yinghao Y; Wen, Li L; Jiang, Keran K; Ma, Yunlong Y; Fan, Rongli R; Chen, Jiali J; Su, Kunkai K; Yang, Zhongli Z; Cui, Wenyan W; Yuan, Wenji W; Jiang, Xianzhong X; Li, Jingjing J; Payne, Thomas J TJ; Wang, Jundong J; Li, Ming D MD
Publication Date: 2018-04-18

Variant appearance in text: rs6495307
PubMed Link: 29666375
Variant Present in the following documents:
  • Main text
  • 41398_2018_Article_130.pdf
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Deep Sequencing of Three Loci Implicated in Large-Scale Genome-Wide Association Study Smoking Meta-Analyses.

Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco
Clark, Shaunna L SL; McClay, Joseph L JL; Adkins, Daniel E DE; Aberg, Karolina A KA; Kumar, Gaurav G; Nerella, Sri S; Xie, Linying L; Collins, Ann L AL; Crowley, James J JJ; Quakenbush, Corey R CR; Hillard, Christopher E CE; Gao, Guimin G; Shabalin, Andrey A AA; Peterson, Roseann E RE; Copeland, William E WE; Silberg, Judy L JL; Maes, Hermine H; Sullivan, Patrick F PF; Costello, Elizabeth J EJ; van den Oord, Edwin J EJ
Publication Date: 2016-05

Variant appearance in text: rs6495307
PubMed Link: 26283763
Variant Present in the following documents:
  • Main text
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Positive Selection on Loci Associated with Drug and Alcohol Dependence.

Plos One
Sadler, Brooke B; Haller, Gabe G; Edenberg, Howard H; Tischfield, Jay J; Brooks, Andy A; Kramer, John J; Schuckit, Marc M; Nurnberger, John J; Goate, Alison A
Publication Date: 2015

Variant appearance in text: rs6495307
PubMed Link: 26270548
Variant Present in the following documents:
  • Main text
  • pone.0134393.pdf
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CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women.

Twin Research And Human Genetics : The Official Journal Of The International Society For Twin Studies
Criado, José R JR; Gizer, Ian R IR; Edenberg, Howard J HJ; Ehlers, Cindy L CL
Publication Date: 2014-04

Variant appearance in text: rs6495307
PubMed Link: 24588897
Variant Present in the following documents:
  • Main text
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Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco
Broms, Ulla U; Wedenoja, Juho J; Largeau, Marine R MR; Korhonen, Tellervo T; Pitkäniemi, Janne J; Keskitalo-Vuokko, Kaisu K; Häppölä, Anja A; Heikkilä, Katri H KH; Heikkilä, Kauko K; Ripatti, Samuli S; Sarin, Antti-Pekka AP; Salminen, Outi O; Paunio, Tiina T; Pergadia, Michele L ML; Madden, Pamela A F PA; Kaprio, Jaakko J; Loukola, Anu A
Publication Date: 2012-06

Variant appearance in text: rs6495307
PubMed Link: 22241830
Variant Present in the following documents:
  • Main text
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Gender-stratified gene and gene-treatment interactions in smoking cessation.

The Pharmacogenomics Journal
Lee, W W; Bergen, A W AW; Swan, G E GE; Li, D D; Liu, J J; Thomas, P P; Tyndale, R F RF; Benowitz, N L NL; Lerman, C C; Conti, D V DV
Publication Date: 2012-12

Variant appearance in text: rs6495307
PubMed Link: 21808284
Variant Present in the following documents:
  • NIHMS305090-supplement-3.pdf
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Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers.

Cancer Causes & Control : Ccc
Sakoda, Lori C LC; Loomis, Melissa M MM; Doherty, Jennifer A JA; Neuhouser, Marian L ML; Barnett, Matt J MJ; Thornquist, Mark D MD; Weiss, Noel S NS; Goodman, Gary E GE; Chen, Chu C
Publication Date: 2011-03

Variant appearance in text: rs6495307
PubMed Link: 21229299
Variant Present in the following documents:
  • Main text
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Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Zhang, Huiping H; Kranzler, Henry R HR; Poling, James J; Gelernter, Joel J
Publication Date: 2010-10

Variant appearance in text: rs6495307
PubMed Link: 20631687
Variant Present in the following documents:
  • Main text
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Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.

Human Molecular Genetics
Hansen, Helen M HM; Xiao, Yuanyuan Y; Rice, Terri T; Bracci, Paige M PM; Wrensch, Margaret R MR; Sison, Jennette D JD; Chang, Jeffery S JS; Smirnov, Ivan V IV; Patoka, Joseph J; Seldin, Michael F MF; Quesenberry, Charles P CP; Kelsey, Karl T KT; Wiencke, John K JK
Publication Date: 2010-09-15

Variant appearance in text: rs6495307
PubMed Link: 20587604
Variant Present in the following documents:
  • Main text
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Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.

Journal Of The National Cancer Institute
Amos, Christopher I CI; Gorlov, Ivan P IP; Dong, Qiong Q; Wu, Xifeng X; Zhang, Huifeng H; Lu, Emily Y EY; Scheet, Paul P; Greisinger, Anthony J AJ; Mills, Gordon B GB; Spitz, Margaret R MR
Publication Date: 2010-08-04

Variant appearance in text: rs6495307
PubMed Link: 20554942
Variant Present in the following documents:
  • Main text
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Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Sherva, Richard R; Kranzler, Henry R HR; Yu, Yi Y; Logue, Mark W MW; Poling, James J; Arias, Albert J AJ; Anton, Raymond F RF; Oslin, David D; Farrer, Lindsay A LA; Gelernter, Joel J
Publication Date: 2010-08

Variant appearance in text: rs6495307
PubMed Link: 20485328
Variant Present in the following documents:
  • Main text
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Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Li, Ming D MD; Xu, Qing Q; Lou, Xiang-Yang XY; Payne, Thomas J TJ; Niu, Tianhua T; Ma, Jennie Z JZ
Publication Date: 2010-04-05

Variant appearance in text: rs6495307
PubMed Link: 19859904
Variant Present in the following documents:
  • Main text
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The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

Cancer Research
Saccone, Nancy L NL; Wang, Jen C JC; Breslau, Naomi N; Johnson, Eric O EO; Hatsukami, Dorothy D; Saccone, Scott F SF; Grucza, Richard A RA; Sun, Lingwei L; Duan, Weimin W; Budde, John J; Culverhouse, Robert C RC; Fox, Louis L; Hinrichs, Anthony L AL; Steinbach, Joseph Henry JH; Wu, Meng M; Rice, John P JP; Goate, Alison M AM; Bierut, Laura J LJ
Publication Date: 2009-09-01

Variant appearance in text: rs6495307
PubMed Link: 19706762
Variant Present in the following documents:
  • Main text
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Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.

Journal Of Hypertension
Montasser, May E ME; Shimmin, Lawrence C LC; Hanis, Craig L CL; Boerwinkle, Eric E; Hixson, James E JE
Publication Date: 2009-03

Variant appearance in text: rs6495307
PubMed Link: 19330903
Variant Present in the following documents:
  • Main text
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Variants in nicotinic receptors and risk for nicotine dependence.

The American Journal Of Psychiatry
Bierut, Laura Jean LJ; Stitzel, Jerry A JA; Wang, Jen C JC; Hinrichs, Anthony L AL; Grucza, Richard A RA; Xuei, Xiaoling X; Saccone, Nancy L NL; Saccone, Scott F SF; Bertelsen, Sarah S; Fox, Louis L; Horton, William J WJ; Breslau, Naomi N; Budde, John J; Cloninger, C Robert CR; Dick, Danielle M DM; Foroud, Tatiana T; Hatsukami, Dorothy D; Hesselbrock, Victor V; Johnson, Eric O EO; Kramer, John J; Kuperman, Samuel S; Madden, Pamela A F PA; Mayo, Kevin K; Nurnberger, John J; Pomerleau, Ovide O; Porjesz, Bernice B; Reyes, Oliver O; Schuckit, Marc M; Swan, Gary G; Tischfield, Jay A JA; Edenberg, Howard J HJ; Rice, John P JP; Goate, Alison M AM
Publication Date: 2008-09

Variant appearance in text: rs6495307
PubMed Link: 18519524
Variant Present in the following documents:
  • Main text
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Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.

Molecular Psychiatry
Wang, J C JC; Grucza, R R; Cruchaga, C C; Hinrichs, A L AL; Bertelsen, S S; Budde, J P JP; Fox, L L; Goldstein, E E; Reyes, O O; Saccone, N N; Saccone, S S; Xuei, X X; Bucholz, K K; Kuperman, S S; Nurnberger, J J; Rice, J P JP; Schuckit, M M; Tischfield, J J; Hesselbrock, V V; Porjesz, B B; Edenberg, H J HJ; Bierut, L J LJ; Goate, A M AM
Publication Date: 2009-05

Variant appearance in text: rs6495307
PubMed Link: 18414406
Variant Present in the following documents:
  • Main text
View BVdb publication page