Cross-Cancer Pleiotropic Associations with Lung Cancer Risk in African Americans.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Jones, Carissa C CC; Bradford, Yuki Y; Amos, Christopher I CI; Blot, William J WJ; Chanock, Stephen J SJ; Harris, Curtis C CC; Schwartz, Ann G AG; Spitz, Margaret R MR; Wiencke, John K JK; Wrensch, Margaret R MR; Wu, Xifeng X; Aldrich, Melinda C MC
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Molecular Psychiatry
Erzurumluoglu, A Mesut AM; Liu, Mengzhen M; Jackson, Victoria E VE; Barnes, Daniel R DR; Datta, Gargi G; Melbourne, Carl A CA; Young, Robin R; Batini, Chiara C; Surendran, Praveen P; Jiang, Tao T; Adnan, Sheikh Daud SD; Afaq, Saima S; Agrawal, Arpana A; Altmaier, Elisabeth E; Antoniou, Antonis C AC; Asselbergs, Folkert W FW; Baumbach, Clemens C; Bierut, Laura L; Bertelsen, Sarah S; Boehnke, Michael M; Bots, Michiel L ML; Brazel, David M DM; Chambers, John C JC; Chang-Claude, Jenny J; Chen, Chu C; Corley, Janie J; Chou, Yi-Ling YL; David, Sean P SP; de Boer, Rudolf A RA; de Leeuw, Christiaan A CA; Dennis, Joe G JG; Dominiczak, Anna F AF; Dunning, Alison M AM; Easton, Douglas F DF; Eaton, Charles C; Elliott, Paul P; Evangelou, Evangelos E; Faul, Jessica D JD; Foroud, Tatiana T; Goate, Alison A; Gong, Jian J; Grabe, Hans J HJ; Haessler, Jeff J; Haiman, Christopher C; Hallmans, Göran G; Hammerschlag, Anke R AR; Harris, Sarah E SE; Hattersley, Andrew A; Heath, Andrew A; Hsu, Chris C; Iacono, William G WG; Kanoni, Stavroula S; Kapoor, Manav M; Kaprio, Jaakko J; Kardia, Sharon L SL; Karpe, Fredrik F; Kontto, Jukka J; Kooner, Jaspal S JS; Kooperberg, Charles C; Kuulasmaa, Kari K; Laakso, Markku M; Lai, Dongbing D; Langenberg, Claudia C; Le, Nhung N; Lettre, Guillaume G; Loukola, Anu A; Luan, Jian'an J; Madden, Pamela A F PAF; Mangino, Massimo M; Marioni, Riccardo E RE; Marouli, Eirini E; Marten, Jonathan J; Martin, Nicholas G NG; McGue, Matt M; Michailidou, Kyriaki K; Mihailov, Evelin E; Moayyeri, Alireza A; Moitry, Marie M; Müller-Nurasyid, Martina M; Naheed, Aliya A; Nauck, Matthias M; Neville, Matthew J MJ; Nielsen, Sune Fallgaard SF; North, Kari K; Perola, Markus M; Pharoah, Paul D P PDP; Pistis, Giorgio G; Polderman, Tinca J TJ; Posthuma, Danielle D; Poulter, Neil N; Qaiser, Beenish B; Rasheed, Asif A; Reiner, Alex A; Renström, Frida F; Rice, John J; Rohde, Rebecca R; Rolandsson, Olov O; Samani, Nilesh J NJ; Samuel, Maria M; Schlessinger, David D; Scholte, Steven H SH; Scott, Robert A RA; Sever, Peter P; Shao, Yaming Y; Shrine, Nick N; Smith, Jennifer A JA; Starr, John M JM; Stirrups, Kathleen K; Stram, Danielle D; Stringham, Heather M HM; Tachmazidou, Ioanna I; Tardif, Jean-Claude JC; Thompson, Deborah J DJ; Tindle, Hilary A HA; Tragante, Vinicius V; Trompet, Stella S; Turcot, Valerie V; Tyrrell, Jessica J; Vaartjes, Ilonca I; van der Leij, Andries R AR; van der Meer, Peter P; Varga, Tibor V TV; Verweij, Niek N; Völzke, Henry H; Wareham, Nicholas J NJ; Warren, Helen R HR; Weir, David R DR; Weiss, Stefan S; Wetherill, Leah L; Yaghootkar, Hanieh H; Yavas, Ersin E; Jiang, Yu Y; Chen, Fang F; Zhan, Xiaowei X; Zhang, Weihua W; Zhao, Wei W; Zhao, Wei W; Zhou, Kaixin K; Amouyel, Philippe P; Blankenberg, Stefan S; Caulfield, Mark J MJ; Chowdhury, Rajiv R; Cucca, Francesco F; Deary, Ian J IJ; Deloukas, Panos P; Di Angelantonio, Emanuele E; Ferrario, Marco M; Ferrières, Jean J; Franks, Paul W PW; Frayling, Tim M TM; Frossard, Philippe P; Hall, Ian P IP; Hayward, Caroline C; Jansson, Jan-Håkan JH; Jukema, J Wouter JW; Kee, Frank F; Männistö, Satu S; Metspalu, Andres A; Munroe, Patricia B PB; Nordestgaard, Børge Grønne BG; Palmer, Colin N A CNA; Salomaa, Veikko V; Sattar, Naveed N; Spector, Timothy T; Strachan, David Peter DP; , ; van der Harst, Pim P; Zeggini, Eleftheria E; Saleheen, Danish D; Butterworth, Adam S AS; Wain, Louise V LV; Abecasis, Goncalo R GR; Danesh, John J; Tobin, Martin D MD; Vrieze, Scott S; Liu, Dajiang J DJ; Howson, Joanna M M JMM
Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.
Scientific Reports
Wang, Junjun J; Liu, Qingyun Q; Yuan, Shuai S; Xie, Weijia W; Liu, Yuan Y; Xiang, Ying Y; Wu, Na N; Wu, Long L; Ma, Xiangyu X; Cai, Tongjian T; Zhang, Yao Y; Sun, Zhifu Z; Li, Yafei Y
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans.
Ebiomedicine
David, Sean P SP; Wang, Ange A; Kapphahn, Kristopher K; Hedlin, Haley H; Desai, Manisha M; Henderson, Michael M; Yang, Lingyao L; Walsh, Kyle M KM; Schwartz, Ann G AG; Wiencke, John K JK; Spitz, Margaret R MR; Wenzlaff, Angela S AS; Wrensch, Margaret R MR; Eaton, Charles B CB; Furberg, Helena H; Mark Brown, W W; Goldstein, Benjamin A BA; Assimes, Themistocles T; Tang, Hua H; Kooperberg, Charles L CL; Quesenberry, Charles P CP; Tindle, Hilary H; Patel, Manali I MI; Amos, Christopher I CI; Bergen, Andrew W AW; Swan, Gary E GE; Stefanick, Marcia L ML
Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.
Plos One
Tseng, Tung-Sung TS; Park, Jong Y JY; Zabaleta, Jovanny J; Moody-Thomas, Sarah S; Sothern, Melinda S MS; Chen, Ted T; Evans, David E DE; Lin, Hui-Yi HY
Genome-wide association study of smoking behaviours among Bangladeshi adults.
Journal Of Medical Genetics
Argos, Maria M; Tong, Lin L; Pierce, Brandon L BL; Rakibuz-Zaman, Muhammad M; Ahmed, Alauddin A; Islam, Tariqul T; Rahman, Mahfuzar M; Paul-Brutus, Rachelle R; Rahaman, Ronald R; Roy, Shantanu S; Jasmine, Farzana F; Kibriya, Muhammad G MG; Ahsan, Habibul H
Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.
Genetic Epidemiology
Stephens, Sarah H SH; Hartz, Sarah M SM; Hoft, Nicole R NR; Saccone, Nancy L NL; Corley, Robin C RC; Hewitt, John K JK; Hopfer, Christian J CJ; Breslau, Naomi N; Coon, Hilary H; Chen, Xiangning X; Ducci, Francesca F; Dueker, Nicole N; Franceschini, Nora N; Frank, Josef J; Han, Younghun Y; Hansel, Nadia N NN; Jiang, Chenhui C; Korhonen, Tellervo T; Lind, Penelope A PA; Liu, Jason J; Lyytikäinen, Leo-Pekka LP; Michel, Martha M; Shaffer, John R JR; Short, Susan E SE; Sun, Juzhong J; Teumer, Alexander A; Thompson, John R JR; Vogelzangs, Nicole N; Vink, Jacqueline M JM; Wenzlaff, Angela A; Wheeler, William W; Yang, Bao-Zhu BZ; Aggen, Steven H SH; Balmforth, Anthony J AJ; Baumeister, Sebastian E SE; Beaty, Terri H TH; Benjamin, Daniel J DJ; Bergen, Andrew W AW; Broms, Ulla U; Cesarini, David D; Chatterjee, Nilanjan N; Chen, Jingchun J; Cheng, Yu-Ching YC; Cichon, Sven S; Couper, David D; Cucca, Francesco F; Dick, Danielle D; Foroud, Tatiana T; Furberg, Helena H; Giegling, Ina I; Gillespie, Nathan A NA; Gu, Fangyi F; Hall, Alistair S AS; Hällfors, Jenni J; Han, Shizhong S; Hartmann, Annette M AM; Heikkilä, Kauko K; Hickie, Ian B IB; Hottenga, Jouke Jan JJ; Jousilahti, Pekka P; Kaakinen, Marika M; Kähönen, Mika M; Koellinger, Philipp D PD; Kittner, Stephen S; Konte, Bettina B; Landi, Maria-Teresa MT; Laatikainen, Tiina T; Leppert, Mark M; Levy, Steven M SM; Mathias, Rasika A RA; McNeil, Daniel W DW; Medland, Sarah E SE; Montgomery, Grant W GW; Murray, Tanda T; Nauck, Matthias M; North, Kari E KE; Paré, Peter D PD; Pergadia, Michele M; Ruczinski, Ingo I; Salomaa, Veikko V; Viikari, Jorma J; Willemsen, Gonneke G; Barnes, Kathleen C KC; Boerwinkle, Eric E; Boomsma, Dorret I DI; Caporaso, Neil N; Edenberg, Howard J HJ; Francks, Clyde C; Gelernter, Joel J; Grabe, Hans Jörgen HJ; Hops, Hyman H; Jarvelin, Marjo-Riitta MR; Johannesson, Magnus M; Kendler, Kenneth S KS; Lehtimäki, Terho T; Magnusson, Patrik K E PK; Marazita, Mary L ML; Marchini, Jonathan J; Mitchell, Braxton D BD; Nöthen, Markus M MM; Penninx, Brenda W BW; Raitakari, Olli O; Rietschel, Marcella M; Rujescu, Dan D; Samani, Nilesh J NJ; Schwartz, Ann G AG; Shete, Sanjay S; Spitz, Margaret M; Swan, Gary E GE; Völzke, Henry H; Veijola, Juha J; Wei, Qingyi Q; Amos, Chris C; Cannon, Dale S DS; Grucza, Richard R; Hatsukami, Dorothy D; Heath, Andrew A; Johnson, Eric O EO; Kaprio, Jaakko J; Madden, Pamela P; Martin, Nicholas G NG; Stevens, Victoria L VL; Weiss, Robert B RB; Kraft, Peter P; Bierut, Laura J LJ; Ehringer, Marissa A MA
Genetic risk for nicotine dependence in the cholinergic system and activation of the brain reward system in healthy adolescents.
Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Nees, F F; Witt, S H SH; Lourdusamy, A A; Vollstädt-Klein, S S; Steiner, S S; Poustka, L L; Banaschewski, T T; Barker, G J GJ; Büchel, C C; Conrod, P J PJ; Frank, J J; Gallinat, J J; Garavan, H H; Heinz, A A; Ittermann, B B; Loth, E E; Mann, K K; Artiges, E E; Paus, T T; Pausova, Z Z; Smolka, M N MN; Struve, M M; Schumann, G G; Rietschel, M M; Flor, H H; ,
Genome-wide meta-analyses of smoking behaviors in African Americans.
Translational Psychiatry
David, S P SP; Hamidovic, A A; Chen, G K GK; Bergen, A W AW; Wessel, J J; Kasberger, J L JL; Brown, W M WM; Petruzella, S S; Thacker, E L EL; Kim, Y Y; Nalls, M A MA; Tranah, G J GJ; Sung, Y J YJ; Ambrosone, C B CB; Arnett, D D; Bandera, E V EV; Becker, D M DM; Becker, L L; Berndt, S I SI; Bernstein, L L; Blot, W J WJ; Broeckel, U U; Buxbaum, S G SG; Caporaso, N N; Casey, G G; Chanock, S J SJ; Deming, S L SL; Diver, W R WR; Eaton, C B CB; Evans, D S DS; Evans, M K MK; Fornage, M M; Franceschini, N N; Harris, T B TB; Henderson, B E BE; Hernandez, D G DG; Hitsman, B B; Hu, J J JJ; Hunt, S C SC; Ingles, S A SA; John, E M EM; Kittles, R R; Kolb, S S; Kolonel, L N LN; Le Marchand, L L; Liu, Y Y; Lohman, K K KK; McKnight, B B; Millikan, R C RC; Murphy, A A; Neslund-Dudas, C C; Nyante, S S; Press, M M; Psaty, B M BM; Rao, D C DC; Redline, S S; Rodriguez-Gil, J L JL; Rybicki, B A BA; Signorello, L B LB; Singleton, A B AB; Smoller, J J; Snively, B B; Spring, B B; Stanford, J L JL; Strom, S S SS; Swan, G E GE; Taylor, K D KD; Thun, M J MJ; Wilson, A F AF; Witte, J S JS; Yamamura, Y Y; Yanek, L R LR; Yu, K K; Zheng, W W; Ziegler, R G RG; Zonderman, A B AB; Jorgenson, E E; Haiman, C A CA; Furberg, H H
Publication Date: 2012-05-22
Variant appearance in text: CHRNA3: 378-1941C>T; rs938682
Genetics of sputum gene expression in chronic obstructive pulmonary disease.
Plos One
Qiu, Weiliang W; Cho, Michael H MH; Riley, John H JH; Anderson, Wayne H WH; Singh, Dave D; Bakke, Per P; Gulsvik, Amund A; Litonjua, Augusto A AA; Lomas, David A DA; Crapo, James D JD; Beaty, Terri H TH; Celli, Bartolome R BR; Rennard, Stephen S; Tal-Singer, Ruth R; Fox, Steven M SM; Silverman, Edwin K EK; Hersh, Craig P CP; ,
Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers.
Cancer Causes & Control : Ccc
Sakoda, Lori C LC; Loomis, Melissa M MM; Doherty, Jennifer A JA; Neuhouser, Marian L ML; Barnett, Matt J MJ; Thornquist, Mark D MD; Weiss, Noel S NS; Goodman, Gary E GE; Chen, Chu C
Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Stadler, Zsofia K ZK; Thom, Peter P; Robson, Mark E ME; Weitzel, Jeffrey N JN; Kauff, Noah D ND; Hurley, Karen E KE; Devlin, Vincent V; Gold, Bert B; Klein, Robert J RJ; Offit, Kenneth K
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
Cancer Research
Saccone, Nancy L NL; Wang, Jen C JC; Breslau, Naomi N; Johnson, Eric O EO; Hatsukami, Dorothy D; Saccone, Scott F SF; Grucza, Richard A RA; Sun, Lingwei L; Duan, Weimin W; Budde, John J; Culverhouse, Robert C RC; Fox, Louis L; Hinrichs, Anthony L AL; Steinbach, Joseph Henry JH; Wu, Meng M; Rice, John P JP; Goate, Alison M AM; Bierut, Laura J LJ
Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.
Cancer Research
Broderick, Peter P; Wang, Yufei Y; Vijayakrishnan, Jayaram J; Matakidou, Athena A; Spitz, Margaret R MR; Eisen, Timothy T; Amos, Christopher I CI; Houlston, Richard S RS
Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.
Human Molecular Genetics
Keskitalo, Kaisu K; Broms, Ulla U; Heliövaara, Markku M; Ripatti, Samuli S; Surakka, Ida I; Perola, Markus M; Pitkäniemi, Janne J; Peltonen, Leena L; Aromaa, Arpo A; Kaprio, Jaakko J
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
Human Molecular Genetics
Wang, Jen C JC; Cruchaga, Carlos C; Saccone, Nancy L NL; Bertelsen, Sarah S; Liu, Pengyuan P; Budde, John P JP; Duan, Weimin W; Fox, Louis L; Grucza, Richard A RA; Kern, Jason J; Mayo, Kevin K; Reyes, Oliver O; Rice, John J; Saccone, Scott F SF; Spiegel, Noah N; Steinbach, Joseph H JH; Stitzel, Jerry A JA; Anderson, Marshall W MW; You, Ming M; Stevens, Victoria L VL; Bierut, Laura J LJ; Goate, Alison M AM; ,
Variants in nicotinic receptors and risk for nicotine dependence.
The American Journal Of Psychiatry
Bierut, Laura Jean LJ; Stitzel, Jerry A JA; Wang, Jen C JC; Hinrichs, Anthony L AL; Grucza, Richard A RA; Xuei, Xiaoling X; Saccone, Nancy L NL; Saccone, Scott F SF; Bertelsen, Sarah S; Fox, Louis L; Horton, William J WJ; Breslau, Naomi N; Budde, John J; Cloninger, C Robert CR; Dick, Danielle M DM; Foroud, Tatiana T; Hatsukami, Dorothy D; Hesselbrock, Victor V; Johnson, Eric O EO; Kramer, John J; Kuperman, Samuel S; Madden, Pamela A F PA; Mayo, Kevin K; Nurnberger, John J; Pomerleau, Ovide O; Porjesz, Bernice B; Reyes, Oliver O; Schuckit, Marc M; Swan, Gary G; Tischfield, Jay A JA; Edenberg, Howard J HJ; Rice, John P JP; Goate, Alison M AM
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.
Molecular Psychiatry
Wang, J C JC; Grucza, R R; Cruchaga, C C; Hinrichs, A L AL; Bertelsen, S S; Budde, J P JP; Fox, L L; Goldstein, E E; Reyes, O O; Saccone, N N; Saccone, S S; Xuei, X X; Bucholz, K K; Kuperman, S S; Nurnberger, J J; Rice, J P JP; Schuckit, M M; Tischfield, J J; Hesselbrock, V V; Porjesz, B B; Edenberg, H J HJ; Bierut, L J LJ; Goate, A M AM
Identification of pharmacogenetic markers in smoking cessation therapy.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Heitjan, Daniel F DF; Guo, Mengye M; Ray, Riju R; Wileyto, E Paul EP; Epstein, Leonard H LH; Lerman, Caryn C