CHRNB4 c.56-2581T>C

Variant ID: 15-78930510-A-G

NM_000750.3(CHRNB4):c.56-2581T>C

This variant was identified in 20 publications

View GRCh38 version.




Publications:


Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners.

International Archives Of Occupational And Environmental Health
Rosenberger, Albert A; Hung, Rayjean J RJ; Christiani, David C DC; Caporaso, Neil E NE; Liu, Geoffrey G; Bojesen, Stig E SE; Le Marchand, Loic L; Haiman, Ch A CA; Albanes, Demetrios D; Aldrich, Melinda C MC; Tardon, Adonina A; Fernández-Tardón, G G; Rennert, Gad G; Field, John K JK; Kiemeney, B B; Lazarus, Philip P; Haugen, Aage A; Zienolddiny, Shanbeh S; Lam, Stephen S; Schabath, Matthew B MB; Andrew, Angeline S AS; Brunnsstöm, Hans H; Goodman, Gary E GE; Doherty, Jennifer A JA; Chen, Chu C; Teare, M Dawn MD; Wichmann, H-Erich HE; Manz, Judith J; Risch, Angela A; Muley, Thomas R TR; Johansson, Mikael M; Brennan, Paul P; Landi, Maria Teresa MT; Amos, Christopher I CI; Pesch, Beate B; Johnen, Georg G; Brüning, Thomas T; Bickeböller, Heike H; Gomolka, Maria M
Publication Date: 2018-11

Variant appearance in text: rs1316971
PubMed Link: 29971594
Variant Present in the following documents:
  • Main text
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A targeted genome association study examining transient receptor potential ion channels, acetylcholine receptors, and adrenergic receptors in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis.

Bmc Medical Genetics
Johnston, Samantha S; Staines, Donald D; Klein, Anne A; Marshall-Gradisnik, Sonya S
Publication Date: 2016-11-11

Variant appearance in text: rs1316971
PubMed Link: 27835969
Variant Present in the following documents:
  • Main text
  • 12881_2016_Article_342.pdf
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Lung Cancer Risk Prediction Using Common SNPs Located in GWAS-Identified Susceptibility Regions.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Weissfeld, Joel L JL; Lin, Yan Y; Lin, Hui-Min HM; Kurland, Brenda F BF; Wilson, David O DO; Fuhrman, Carl R CR; Pennathur, Arjun A; Romkes, Marjorie M; Nukui, Tomoko T; Yuan, Jian-Min JM; Siegfried, Jill M JM; Diergaarde, Brenda B
Publication Date: 2015-11

Variant appearance in text: rs1316971
PubMed Link: 26352532
Variant Present in the following documents:
  • Main text
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Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder.

Psychiatry Research
Kimbrel, Nathan A NA; Garrett, Melanie E ME; Dennis, Michelle F MF; Liu, Yutao Y; Patanam, Ilyas I; Workgroup, Va Mid-Atlantic Mirecc VM; Ashley-Koch, Allison E AE; Hauser, Michael A MA; Beckham, Jean C JC
Publication Date: 2015-09-30

Variant appearance in text: rs1316971
PubMed Link: 26184988
Variant Present in the following documents:
  • Main text
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Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.

Plos One
Tseng, Tung-Sung TS; Park, Jong Y JY; Zabaleta, Jovanny J; Moody-Thomas, Sarah S; Sothern, Melinda S MS; Chen, Ted T; Evans, David E DE; Lin, Hui-Yi HY
Publication Date: 2014

Variant appearance in text: rs1316971
PubMed Link: 25233467
Variant Present in the following documents:
  • Main text
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Joint association of nicotinic acetylcholine receptor variants with abdominal obesity in American Indians: the Strong Heart Family Study.

Plos One
Zhu, Yun Y; Yang, Jingyun J; Yeh, Fawn F; Cole, Shelley A SA; Haack, Karin K; Lee, Elisa T ET; Howard, Barbara V BV; Zhao, Jinying J
Publication Date: 2014

Variant appearance in text: rs1316971
PubMed Link: 25036316
Variant Present in the following documents:
  • Main text
  • pone.0102220.pdf
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Genetic variants in nicotinic acetylcholine receptor genes jointly contribute to kidney function in American Indians: the Strong Heart Family Study.

Journal Of Hypertension
Zhu, Yun Y; Yang, Jingyun J; Li, Shengxu S; Cole, Shelley A SA; Haack, Karin K; Umans, Jason G JG; Franceschini, Nora N; Howard, Barbara V BV; Lee, Elisa T ET; Zhao, Jinying J
Publication Date: 2014-05

Variant appearance in text: rs1316971
PubMed Link: 24569419
Variant Present in the following documents:
  • Main text
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Genetic risk for nicotine dependence in the cholinergic system and activation of the brain reward system in healthy adolescents.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Nees, F F; Witt, S H SH; Lourdusamy, A A; Vollstädt-Klein, S S; Steiner, S S; Poustka, L L; Banaschewski, T T; Barker, G J GJ; Büchel, C C; Conrod, P J PJ; Frank, J J; Gallinat, J J; Garavan, H H; Heinz, A A; Ittermann, B B; Loth, E E; Mann, K K; Artiges, E E; Paus, T T; Pausova, Z Z; Smolka, M N MN; Struve, M M; Schumann, G G; Rietschel, M M; Flor, H H; ,
Publication Date: 2013-10

Variant appearance in text: rs1316971
PubMed Link: 23689675
Variant Present in the following documents:
  • Main text
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Joint associations of 61 genetic variants in the nicotinic acetylcholine receptor genes with subclinical atherosclerosis in American Indians: a gene-family analysis.

Circulation. Cardiovascular Genetics
Yang, Jingyun J; Zhu, Yun Y; Lee, Elisa T ET; Zhang, Ying Y; Cole, Shelley A SA; Haack, Karin K; Best, Lyle G LG; Devereux, Richard B RB; Roman, Mary J MJ; Howard, Barbara V BV; Zhao, Jinying J
Publication Date: 2013-02

Variant appearance in text: rs1316971
PubMed Link: 23264444
Variant Present in the following documents:
  • Main text
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The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

Behavior Genetics
Lubke, Gitta H GH; Stephens, Sarah H SH; Lessem, Jeffrey M JM; Hewitt, John K JK; Ehringer, Marissa A MA
Publication Date: 2012-07

Variant appearance in text: rs1316971
PubMed Link: 22382757
Variant Present in the following documents:
  • Main text
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Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.

Behavior Genetics
Stephens, Sarah H SH; Hoft, Nicole R NR; Schlaepfer, Isabel R IR; Young, Susan E SE; Corley, Robin C RC; McQueen, Matthew B MB; Hopfer, Christian C; Crowley, Thomas T; Stallings, Michael M; Hewitt, John J; Ehringer, Marissa A MA
Publication Date: 2012-05

Variant appearance in text: rs1316971
PubMed Link: 22042234
Variant Present in the following documents:
  • Main text
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Genetics of sputum gene expression in chronic obstructive pulmonary disease.

Plos One
Qiu, Weiliang W; Cho, Michael H MH; Riley, John H JH; Anderson, Wayne H WH; Singh, Dave D; Bakke, Per P; Gulsvik, Amund A; Litonjua, Augusto A AA; Lomas, David A DA; Crapo, James D JD; Beaty, Terri H TH; Celli, Bartolome R BR; Rennard, Stephen S; Tal-Singer, Ruth R; Fox, Steven M SM; Silverman, Edwin K EK; Hersh, Craig P CP; ,
Publication Date: 2011

Variant appearance in text: rs1316971
PubMed Link: 21949713
Variant Present in the following documents:
  • Main text
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Gender-stratified gene and gene-treatment interactions in smoking cessation.

The Pharmacogenomics Journal
Lee, W W; Bergen, A W AW; Swan, G E GE; Li, D D; Liu, J J; Thomas, P P; Tyndale, R F RF; Benowitz, N L NL; Lerman, C C; Conti, D V DV
Publication Date: 2012-12

Variant appearance in text: rs1316971
PubMed Link: 21808284
Variant Present in the following documents:
  • NIHMS305090-supplement-3.pdf
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Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers.

Cancer Causes & Control : Ccc
Sakoda, Lori C LC; Loomis, Melissa M MM; Doherty, Jennifer A JA; Neuhouser, Marian L ML; Barnett, Matt J MJ; Thornquist, Mark D MD; Weiss, Noel S NS; Goodman, Gary E GE; Chen, Chu C
Publication Date: 2011-03

Variant appearance in text: rs1316971
PubMed Link: 21229299
Variant Present in the following documents:
  • Main text
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Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.

Human Molecular Genetics
Keskitalo, Kaisu K; Broms, Ulla U; Heliövaara, Markku M; Ripatti, Samuli S; Surakka, Ida I; Perola, Markus M; Pitkäniemi, Janne J; Peltonen, Leena L; Aromaa, Arpo A; Kaprio, Jaakko J
Publication Date: 2009-10-15

Variant appearance in text: rs1316971
PubMed Link: 19628476
Variant Present in the following documents:
  • Main text
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Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.

Journal Of Hypertension
Montasser, May E ME; Shimmin, Lawrence C LC; Hanis, Craig L CL; Boerwinkle, Eric E; Hixson, James E JE
Publication Date: 2009-03

Variant appearance in text: rs1316971
PubMed Link: 19330903
Variant Present in the following documents:
  • Main text
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Nicotinic receptor gene variants influence susceptibility to heavy smoking.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Stevens, Victoria L VL; Bierut, Laura J LJ; Talbot, Jeffrey T JT; Wang, Jen C JC; Sun, Juzhong J; Hinrichs, Anthony L AL; Thun, Michael J MJ; Goate, Alison A; Calle, Eugenia E EE
Publication Date: 2008-12

Variant appearance in text: rs1316971
PubMed Link: 19029397
Variant Present in the following documents:
  • Main text
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Identification of pharmacogenetic markers in smoking cessation therapy.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Heitjan, Daniel F DF; Guo, Mengye M; Ray, Riju R; Wileyto, E Paul EP; Epstein, Leonard H LH; Lerman, Caryn C
Publication Date: 2008-09-05

Variant appearance in text: rs1316971
PubMed Link: 18165968
Variant Present in the following documents:
  • Main text
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The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.

Biological Psychiatry
Schlaepfer, Isabel R IR; Hoft, Nicole R NR; Collins, Allan C AC; Corley, Robin P RP; Hewitt, John K JK; Hopfer, Christian J CJ; Lessem, Jeffrey M JM; McQueen, Matthew B MB; Rhee, Soo Hyun SH; Ehringer, Marissa A MA
Publication Date: 2008-06-01

Variant appearance in text: rs1316971
PubMed Link: 18163978
Variant Present in the following documents:
  • Main text
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No evidence for association between 19 cholinergic genes and bipolar disorder.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Shi, Jiajun J; Hattori, Eiji E; Zou, Hongwei H; Badner, Judith A JA; Christian, Susan L SL; Gershon, Elliot S ES; Liu, Chunyu C
Publication Date: 2007-09-05

Variant appearance in text: rs1316971
PubMed Link: 17373692
Variant Present in the following documents:
  • Main text
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