Coffee consumption and risk of breast cancer: A Mendelian randomization study.
Plos One
Ellingjord-Dale, Merete M; Papadimitriou, Nikos N; Katsoulis, Michail M; Yee, Chew C; Dimou, Niki N; Gill, Dipender D; Aune, Dagfinn D; Ong, Jue-Sheng JS; MacGregor, Stuart S; Elsworth, Benjamin B; Lewis, Sarah J SJ; Martin, Richard M RM; Riboli, Elio E; Tsilidis, Konstantinos K KK
An Integrative Phenotype-Genotype Approach Using Phenotypic Characteristics from the UAE National Diabetes Study Identifies HSD17B12 as a Candidate Gene for Obesity and Type 2 Diabetes.
Genes
Hachim, Mahmood Y MY; Aljaibeji, Hayat H; Hamoudi, Rifat A RA; Hachim, Ibrahim Y IY; Elemam, Noha M NM; Mohammed, Abdul Khader AK; Salehi, Albert A; Taneera, Jalal J; Sulaiman, Nabil N
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
Molecular Genetics & Genomic Medicine
Lule, Swaib A SA; Mentzer, Alexander J AJ; Namara, Benigna B; Muwenzi, Allan G AG; Nassanga, Beatrice B; Kizito, Dennison D; Akurut, Helen H; Lubyayi, Lawrence L; Tumusiime, Josephine J; Zziwa, Christopher C; Akello, Florence F; Gurdasani, Deept D; Sandhu, Manjinder M; Smeeth, Liam L; Elliott, Alison M AM; Webb, Emily L EL
Genome-wide association study of medication-use and associated disease in the UK Biobank.
Nature Communications
Wu, Yeda Y; Byrne, Enda M EM; Zheng, Zhili Z; Kemper, Kathryn E KE; Yengo, Loic L; Mallett, Andrew J AJ; Yang, Jian J; Visscher, Peter M PM; Wray, Naomi R NR
FURIN variant associations with postexercise hypotension are intensity and race dependent.
Physiological Reports
Cilhoroz, Burak T BT; Schifano, Elizabeth D ED; Panza, Gregory A GA; Ash, Garrett I GI; Corso, Lauren L; Chen, Ming-Hui MH; Deshpande, Ved V; Zaleski, Amanda A; Farinatti, Paulo P; Santos, Lucas P LP; Taylor, Beth A BA; O'Neill, Rachel J RJ; Thompson, Paul D PD; Pescatello, Linda S LS
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation.
Nature Genetics
Gamazon, Eric R ER; Segrè, Ayellet V AV; van de Bunt, Martijn M; Wen, Xiaoquan X; Xi, Hualin S HS; Hormozdiari, Farhad F; Ongen, Halit H; Konkashbaev, Anuar A; Derks, Eske M EM; Aguet, François F; Quan, Jie J; , ; Nicolae, Dan L DL; Eskin, Eleazar E; Kellis, Manolis M; Getz, Gad G; McCarthy, Mark I MI; Dermitzakis, Emmanouil T ET; Cox, Nancy J NJ; Ardlie, Kristin G KG
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.
Nature Communications
Barbeira, Alvaro N AN; Dickinson, Scott P SP; Bonazzola, Rodrigo R; Zheng, Jiamao J; Wheeler, Heather E HE; Torres, Jason M JM; Torstenson, Eric S ES; Shah, Kaanan P KP; Garcia, Tzintzuni T; Edwards, Todd L TL; Stahl, Eli A EA; Huckins, Laura M LM; , ; Nicolae, Dan L DL; Cox, Nancy J NJ; Im, Hae Kyung HK
Applicability of Precision Medicine Approaches to Managing Hypertension in Rural Populations.
Journal Of Personalized Medicine
Halladay, Jacqueline R JR; Lenhart, Kaitlin C KC; Robasky, Kimberly K; Jones, Wendell W; Homan, Wayne F WF; Cummings, Doyle M DM; Cené, Crystal W CW; Hinderliter, Alan L AL; Miller, Cassandra L CL; Donahue, Katrina E KE; Garcia, Beverly A BA; Keyserling, Thomas C TC; Ammerman, Alice S AS; Patterson, Cam C; DeWalt, Darren A DA; Johnston, Larry F LF; Willis, Monte S MS; Schisler, Jonathan C JC
Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.
Scientific Reports
Sofer, Tamar T; Wong, Quenna Q; Hartwig, Fernando P FP; Taylor, Kent K; Warren, Helen R HR; Evangelou, Evangelos E; Cabrera, Claudia P CP; Levy, Daniel D; Kramer, Holly H; Lange, Leslie A LA; Horta, Bernardo L BL; , ; Kerr, Kathleen F KF; Reiner, Alex P AP; Franceschini, Nora N
Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway.
Scientific Reports
Rippe, Catarina C; Zhu, Baoyi B; Krawczyk, Katarzyna K KK; Bavel, Ed Van EV; Albinsson, Sebastian S; Sjölund, Jonas J; Bakker, Erik N T P ENTP; Swärd, Karl K
Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans.
Plos One
Franceschini, Nora N; Carty, Cara L CL; Lu, Yingchang Y; Tao, Ran R; Sung, Yun Ju YJ; Manichaikul, Ani A; Haessler, Jeff J; Fornage, Myriam M; Schwander, Karen K; Zubair, Niha N; Bien, Stephanie S; Hindorff, Lucia A LA; Guo, Xiuqing X; Bielinski, Suzette J SJ; Ehret, Georg G; Kaufman, Joel D JD; Rich, Stephen S SS; Carlson, Christopher S CS; Bottinger, Erwin P EP; North, Kari E KE; Rao, D C DC; Chakravarti, Aravinda A; Barrett, Paula Q PQ; Loos, Ruth J F RJ; Buyske, Steven S; Kooperberg, Charles C
Systolic Blood Pressure and Risk of Type 2 Diabetes: A Mendelian Randomization Study.
Diabetes
Aikens, Rachael C RC; Zhao, Wei W; Saleheen, Danish D; Reilly, Muredach P MP; Epstein, Stephen E SE; Tikkanen, Emmi E; Salomaa, Veikko V; Voight, Benjamin F BF
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Nature Genetics
Ehret, Georg B GB; Ferreira, Teresa T; Chasman, Daniel I DI; Jackson, Anne U AU; Schmidt, Ellen M EM; Johnson, Toby T; Thorleifsson, Gudmar G; Luan, Jian'an J; Donnelly, Lousie A LA; Kanoni, Stavroula S; Petersen, Ann-Kristin AK; Pihur, Vasyl V; Strawbridge, Rona J RJ; Shungin, Dmitry D; Hughes, Maria F MF; Meirelles, Osorio O; Kaakinen, Marika M; Bouatia-Naji, Nabila N; Kristiansson, Kati K; Shah, Sonia S; Kleber, Marcus E ME; Guo, Xiuqing X; Lyytikäinen, Leo-Pekka LP; Fava, Cristiano C; Eriksson, Niclas N; Nolte, Ilja M IM; Magnusson, Patrik K PK; Salfati, Elias L EL; Rallidis, Loukianos S LS; Theusch, Elizabeth E; Smith, Andrew J P AJP; Folkersen, Lasse L; Witkowska, Kate K; Pers, Tune H TH; Joehanes, Roby R; Kim, Stuart K SK; Lataniotis, Lazaros L; Jansen, Rick R; Johnson, Andrew D AD; Warren, Helen H; Kim, Young Jin YJ; Zhao, Wei W; Wu, Ying Y; Tayo, Bamidele O BO; Bochud, Murielle M; , ; , ; , ; Absher, Devin D; Adair, Linda S LS; Amin, Najaf N; Arking, Dan E DE; Axelsson, Tomas T; 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Utility of blood pressure genetic risk score in admixed Hispanic samples.
Journal Of Human Hypertension
Beecham, A H AH; Wang, L L; Vasudeva, N N; Liu, Z Z; Dong, C C; Goldschmidt-Clermont, P J PJ; Pericak-Vance, M A MA; Rundek, T T; Seo, D D; Blanton, S H SH; Sacco, R L RL; Beecham, G W GW
Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.
Plos One
Bis, Joshua C JC; Sitlani, Colleen C; Irvin, Ryan R; Avery, Christy L CL; Smith, Albert Vernon AV; Sun, Fangui F; Evans, Daniel S DS; Musani, Solomon K SK; Li, Xiaohui X; Trompet, Stella S; Krijthe, Bouwe P BP; Harris, Tamara B TB; Quibrera, P Miguel PM; Brody, Jennifer A JA; Demissie, Serkalem S; Davis, Barry R BR; Wiggins, Kerri L KL; Tranah, Gregory J GJ; Lange, Leslie A LA; Sotoodehnia, Nona N; Stott, David J DJ; Franco, Oscar H OH; Launer, Lenore J LJ; Stürmer, Til T; Taylor, Kent D KD; Cupples, L Adrienne LA; Eckfeldt, John H JH; Smith, Nicholas L NL; Liu, Yongmei Y; Wilson, James G JG; Heckbert, Susan R SR; Buckley, Brendan M BM; Ikram, M Arfan MA; Boerwinkle, Eric E; Chen, Yii-Der Ida YD; de Craen, Anton J M AJ; Uitterlinden, Andre G AG; Rotter, Jerome I JI; Ford, Ian I; Hofman, Albert A; Sattar, Naveed N; Slagboom, P Eline PE; Westendorp, Rudi G J RG; Gudnason, Vilmundur V; Vasan, Ramachandran S RS; Lumley, Thomas T; Cummings, Steven R SR; Taylor, Herman A HA; Post, Wendy W; Jukema, J Wouter JW; Stricker, Bruno H BH; Whitsel, Eric A EA; Psaty, Bruce M BM; Arnett, Donna D
Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes.
Hypertension (Dallas, Tex. : 1979)
Andreassen, Ole A OA; McEvoy, Linda K LK; Thompson, Wesley K WK; Wang, Yunpeng Y; Reppe, Sjur S; Schork, Andrew J AJ; Zuber, Verena V; Barrett-Connor, Elizabeth E; Gautvik, Kaare K; Aukrust, Pål P; Karlsen, Tom H TH; Djurovic, Srdjan S; Desikan, Rahul S RS; Dale, Anders M AM; ,
Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.
Plos One
Bhatnagar, Pallav P; Barron-Casella, Emily E; Bean, Christopher J CJ; Milton, Jacqueline N JN; Baldwin, Clinton T CT; Steinberg, Martin H MH; Debaun, Michael M; Casella, James F JF; Arking, Dan E DE
Gentrepid V2.0: a web server for candidate disease gene prediction.
Bmc Bioinformatics
Ballouz, Sara S; Liu, Jason Y JY; George, Richard A RA; Bains, Naresh N; Liu, Arthur A; Oti, Martin M; Gaeta, Bruno B; Fatkin, Diane D; Wouters, Merridee A MA
Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium.
American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation
Olden, Matthias M; Teumer, Alexander A; Bochud, Murielle M; Pattaro, Cristian C; Köttgen, Anna A; Turner, Stephen T ST; Rettig, Rainer R; Chen, Ming-Huei MH; Dehghan, Abbas A; Bastardot, Francois F; Schmidt, Reinhold R; Vollenweider, Peter P; Schunkert, Heribert H; Reilly, Muredach P MP; Fornage, Myriam M; Launer, Lenore J LJ; Verwoert, Germaine C GC; Mitchell, Gary F GF; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Cheng, Ching-Yu CY; Sim, Xueling X; Siscovick, David S DS; Coresh, Josef J; Kao, W H Linda WH; Fox, Caroline S CS; O'Seaghdha, Conall M CM; ,
Large-scale association analysis identifies new risk loci for coronary artery disease.
Nature Genetics
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Genetic predisposition to high blood pressure associates with cardiovascular complications among patients with type 2 diabetes: two independent studies.
Diabetes
Qi, Qibin Q; Forman, John P JP; Jensen, Majken K MK; Flint, Alan A; Curhan, Gary C GC; Rimm, Eric B EB; Hu, Frank B FB; Qi, Lu L
Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
European Heart Journal
Fedorowski, Artur A; Franceschini, Nora N; Brody, Jennifer J; Liu, Chunyu C; Verwoert, Germaine C GC; Boerwinkle, Eric E; Couper, David D; Rice, Kenneth M KM; Rotter, Jerome I JI; Mattace-Raso, Francesco F; Uitterlinden, Andre A; Hofman, Albert A; Almgren, Peter P; Sjögren, Marketa M; Hedblad, Bo B; Larson, Martin G MG; Newton-Cheh, Christopher C; Wang, Thomas J TJ; Rose, Kathryn M KM; Psaty, Bruce M BM; Levy, Daniel D; Witteman, Jacqueline J; Melander, Olle O
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Nature
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