Publications:

Antitumor activity of the dual PI3K/mTOR inhibitor gedatolisib and the involvement of ABCB1 in gedatolisib resistance in canine tumor cells.

Oncology Reports

Murase, Yusuke Y; Hosoya, Kenji K; Sato, Takachika T; Kim, Sangho S; Okumura, Masahiro M

Publication Date: 2022-04

Variant appearance in text: TSC2: S422D

PubMed Link: 35088890

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The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation.

Current Biology : Cb

Csibi, Alfredo A; Lee, Gina G; Yoon, Sang-Oh SO; Tong, Haoxuan H; Ilter, Didem D; Elia, Ilaria I; Fendt, Sarah-Maria SM; Roberts, Thomas M TM; Blenis, John J

Publication Date: 2014-10-06

Variant appearance in text: TSC2: S422D

PubMed Link: 25220053

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Integration of mTOR and estrogen-ERK2 signaling in lymphangioleiomyomatosis pathogenesis.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Gu, Xiaoxiao X; Yu, Jane J JJ; Ilter, Didem D; Blenis, Nickolas N; Henske, Elizabeth Petri EP; Blenis, John J

Publication Date: 2013-09-10

Variant appearance in text: TSC2: S422D

PubMed Link: 23983265

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Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

Cancer Research

Sherk, Andrea B AB; Frigo, Daniel E DE; Schnackenberg, Christine G CG; Bray, Jeffrey D JD; Laping, Nicholas J NJ; Trizna, Walter W; Hammond, Marlys M; Patterson, Jaclyn R JR; Thompson, Scott K SK; Kazmin, Dmitri D; Norris, John D JD; McDonnell, Donald P DP

Publication Date: 2008-09-15

Variant appearance in text: TSC2: S422D

PubMed Link: 18794135

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The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

The Embo Journal

Shahbazian, David D; Roux, Philippe P PP; Mieulet, Virginie V; Cohen, Michael S MS; Raught, Brian B; Taunton, Jack J; Hershey, John W B JW; Blenis, John J; Pende, Mario M; Sonenberg, Nahum N

Publication Date: 2006-06-21

Variant appearance in text: TSC2: Ser422Asp

PubMed Link: 16763566

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