TSC2 c.3802C>T ;(p.R1268C)

Variant ID: 16-2131787-C-T

NM_000548.3(TSC2):c.3802C>T;(p.R1268C)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine
Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y
Publication Date: 2022-07

Variant appearance in text: TSC2: 3802C>T; R1268C
PubMed Link: 35393784
Variant Present in the following documents:
  • CAM4-11-2767-s001.xlsx, sheet 1
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: TSC2: 3802C>T; R1268C
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer
Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F
Publication Date: 2020

Variant appearance in text: TSC2: 3802C>T; R1268C
PubMed Link: 33145402
Variant Present in the following documents:
  • 41523_2020_201_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology
Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M
Publication Date: 2020-01-07

Variant appearance in text: TSC2: 3802C>T; R1268C
PubMed Link: 31925297
Variant Present in the following documents:
  • 42003_2019_736_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance.

Plos One
O'Keefe, Rachel A RA; Bhola, Neil E NE; Lee, David S DS; Johnson, Daniel E DE; Grandis, Jennifer R JR
Publication Date: 2020

Variant appearance in text: TSC2: R1268C
PubMed Link: 31914141
Variant Present in the following documents:
  • Main text
  • pone.0227261.pdf
  • pone.0227261.s012.xlsx, sheet 1
  • pone.0227261.s011.xlsx, sheet 1
  • pone.0227261.s010.xlsx, sheet 1
  • pone.0227261.s013.xlsx, sheet 1
View BVdb publication page



Exploiting high-throughput cell line drug screening studies to identify candidate therapeutic agents in head and neck cancer.

Bmc Pharmacology & Toxicology
Nichols, Anthony C AC; Black, Morgan M; Yoo, John J; Pinto, Nicole N; Fernandes, Andrew A; Haibe-Kains, Benjamin B; Boutros, Paul C PC; Barrett, John W JW
Publication Date: 2014-11-27

Variant appearance in text: TSC2: R1268C
PubMed Link: 25428177
Variant Present in the following documents:
  • 40360_2014_350_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection.

Molecular Cancer Research : Mcr
Li, Hua H; Wawrose, John S JS; Gooding, William E WE; Garraway, Levi A LA; Lui, Vivian Wai Yan VW; Peyser, Noah D ND; Grandis, Jennifer R JR
Publication Date: 2014-04

Variant appearance in text: TSC2: R1268C
PubMed Link: 24425785
Variant Present in the following documents:
  • Main text
View BVdb publication page