The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years.
Clinical Epigenetics
Soto-Ramírez, Nelís N; Arshad, Syed Hasan SH; Holloway, John W JW; Zhang, Hongmei H; Schauberger, Eric E; Ewart, Susan S; Patil, Veeresh V; Karmaus, Wilfried W
IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor α antagonist.
The Journal Of Allergy And Clinical Immunology
Slager, Rebecca E RE; Otulana, Babatunde A BA; Hawkins, Gregory A GA; Yen, Yu Ping YP; Peters, Stephen P SP; Wenzel, Sally E SE; Meyers, Deborah A DA; Bleecker, Eugene R ER