Publications:

Loss of NF1 in melanoma confers sensitivity to SYK kinase inhibition.

Cancer Research

Abecunas, Cara C; Whitehead, Christopher E CE; Ziemke, Elizabeth K EK; Baumann, Douglas G DG; Frankowski-McGregor, Christy L CL; Sebolt-Leopold, Judith S JS; Fallahi-Sichani, Mohammad M

Publication Date: 2022-11-21

Variant appearance in text: ERK1: D300e

PubMed Link: 36409827

Variant Present in the following documents:

• Main text
• 316.pdf

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Identifying mutant-specific multi-drug combinations using comparative network reconstruction.

Iscience

Bosdriesz, Evert E; Fernandes Neto, João M JM; Sieber, Anja A; Bernards, René R; Blüthgen, Nils N; Wessels, Lodewyk F A LFA

Publication Date: 2022-08-19

Variant appearance in text: ERK1: D300e

PubMed Link: 35992065

Variant Present in the following documents:

• Main text
• main.pdf

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Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells.

Elife

Li, Wenyang W; Chen, Jennifer Y JY; Sun, Cheng C; Sparks, Robert P RP; Pantano, Lorena L; Rahman, Raza-Ur RU; Moran, Sean P SP; Pondick, Joshua V JV; Kirchner, Rory R; Wrobel, David D; Bieler, Michael M; Sauer, Achim A; Ho Sui, Shannan J SJ; Doerner, Julia F JF; Rippmann, Jörg F JF; Mullen, Alan C AC

Publication Date: 2022-05-26

Variant appearance in text: ERK1: D300e

PubMed Link: 35617485

Variant Present in the following documents:

• Main text
• elife-74513.pdf

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Mutations That Confer Drug-Resistance, Oncogenicity and Intrinsic Activity on the ERK MAP Kinases-Current State of the Art.

Cells

Smorodinsky-Atias, Karina K; Soudah, Nadine N; Engelberg, David D

Publication Date: 2020-01-06

Variant appearance in text: ERK1: D300E

PubMed Link: 31935908

Variant Present in the following documents:

• Main text
• cells-09-00129.pdf

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Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Cell

Creixell, Pau P; Schoof, Erwin M EM; Simpson, Craig D CD; Longden, James J; Miller, Chad J CJ; Lou, Hua Jane HJ; Perryman, Lara L; Cox, Thomas R TR; Zivanovic, Nevena N; Palmeri, Antonio A; Wesolowska-Andersen, Agata A; Helmer-Citterich, Manuela M; Ferkinghoff-Borg, Jesper J; Itamochi, Hiroaki H; Bodenmiller, Bernd B; Erler, Janine T JT; Turk, Benjamin E BE; Linding, Rune R

Publication Date: 2015-09-24

Variant appearance in text: MAPK3: D300E

PubMed Link: 26388441

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

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