VKORC1 c.283+837T>C

Variant ID: 16-31103796-A-G

NM_024006.4(VKORC1):c.283+837T>C

This variant was identified in 79 publications

View GRCh38 version.




Publications:


Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases.

Nature Genetics
de Klein, Niek N; Tsai, Ellen A EA; Vochteloo, Martijn M; Baird, Denis D; Huang, Yunfeng Y; Chen, Chia-Yen CY; van Dam, Sipko S; Oelen, Roy R; Deelen, Patrick P; Bakker, Olivier B OB; El Garwany, Omar O; Ouyang, Zhengyu Z; Marshall, Eric E EE; Zavodszky, Maria I MI; van Rheenen, Wouter W; Bakker, Mark K MK; Veldink, Jan J; Gaunt, Tom R TR; Runz, Heiko H; Franke, Lude L; Westra, Harm-Jan HJ
Publication Date: 2023-02-23

Variant appearance in text: rs2359612
PubMed Link: 36823318
Variant Present in the following documents:
  • Main text
  • 41588_2023_Article_1300.pdf
View BVdb publication page



Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.

Ejhaem
Safa, Firas F; Rasmussen, Terri T; Lobelle-Rich, Patricia P; Collier, Stephanie S; Milligan, Nicholas N; Schmeig, John J; Schmid, Janet J; Wiewiorowski, Carol C; Totaro, Denise D; Brown, Theresa C TC; Satyavarapu, Ishwarya I; Badoo, Melody M; Ungerleider, Nathan N; Flemington, Erik K EK; Safah, Hana H; Saba, Nakhle S NS
Publication Date: 2022-11

Variant appearance in text: rs2359612
PubMed Link: 36467812
Variant Present in the following documents:
  • JHA2-3-1326-s001.xlsx, sheet 1
View BVdb publication page



Analysis of clinically relevant variants from ancestrally diverse Asian genomes.

Nature Communications
Chan, Sock Hoai SH; Bylstra, Yasmin Y; Teo, Jing Xian JX; Kuan, Jyn Ling JL; Bertin, Nicolas N; Gonzalez-Porta, Mar M; Hebrard, Maxime M; Tirado-Magallanes, Roberto R; Tan, Joanna Hui Juan JHJ; Jeyakani, Justin J; Li, Zhihui Z; Chai, Jin Fang JF; Chong, Yap Seng YS; Davila, Sonia S; Goh, Liuh Ling LL; Lee, Eng Sing ES; Wong, Eleanor E; Wong, Tien Yin TY; , ; Prabhakar, Shyam S; Liu, Jianjun J; Cheng, Ching-Yu CY; Eisenhaber, Birgit B; Karnani, Neerja N; Leong, Khai Pang KP; Sim, Xueling X; Yeo, Khung Keong KK; Chambers, John C JC; Tai, E-Shyong ES; Tan, Patrick P; Jamuar, Saumya S SS; Ngeow, Joanne J; Lim, Weng Khong WK
Publication Date: 2022-11-05

Variant appearance in text: rs2359612
PubMed Link: 36335097
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_34116.pdf
View BVdb publication page



Genome screening, reporting, and genetic counseling for healthy populations.

Human Genetics
Casalino, Selina S; Frangione, Erika E; Chung, Monica M; MacDonald, Georgia G; Chowdhary, Sunakshi S; Mighton, Chloe C; Faghfoury, Hanna H; Bombard, Yvonne Y; Strug, Lisa L; Pugh, Trevor J TJ; Simpson, Jared J; Arnoldo, Saranya S; Aujla, Navneet N; Bearss, Erin E; Binnie, Alexandra A; Borgundvaag, Bjug B; Chertkow, Howard H; Clausen, Marc M; Dagher, Marc M; Devine, Luke L; Di Iorio, David D; Friedman, Steven Marc SM; Fung, Chun Yiu Jordan CYJ; Gingras, Anne-Claude AC; Goneau, Lee W LW; Kaushik, Deepanjali D; Khan, Zeeshan Z; Lapadula, Elisa E; Lu, Tiffany T; Mazzulli, Tony T; McGeer, Allison A; McLeod, Shelley L SL; Morgan, Gregory G; Richardson, David D; Singh, Harpreet H; Stern, Seth S; Taher, Ahmed A; Wong, Iris I; Zarei, Natasha N; Greenfeld, Elena E; Hao, Limin L; Lebo, Matthew M; Lane, William W; Noor, Abdul A; Taher, Jennifer J; Lerner-Ellis, Jordan J
Publication Date: 2022-11-04

Variant appearance in text: rs2359612
PubMed Link: 36331656
Variant Present in the following documents:
  • 439_2022_2480_MOESM5_ESM.pdf
View BVdb publication page



Genetic Variation among Pharmacogenes in the Sardinian Population.

International Journal Of Molecular Sciences
Idda, Maria Laura ML; Zoledziewska, Magdalena M; Urru, Silvana Anna Maria SAM; McInnes, Gregory G; Bilotta, Alice A; Nuvoli, Viola V; Lodde, Valeria V; Orrù, Sandro S; Schlessinger, David D; Cucca, Francesco F; Floris, Matteo M
Publication Date: 2022-09-02

Variant appearance in text: rs2359612
PubMed Link: 36077453
Variant Present in the following documents:
  • ijms-23-10058.pdf
View BVdb publication page



Cross-ethnic analysis of common gene variants in hemostasis show lopsided representation of global populations in genetic databases.

Bmc Medical Genomics
Osman, Abdimajid A; Jonasson, Jon J
Publication Date: 2022-03-25

Variant appearance in text: rs2359612
PubMed Link: 35337356
Variant Present in the following documents:
  • Main text
  • 12920_2022_Article_1220.pdf
View BVdb publication page



Genetic Polymorphism of Drug Metabolic Gene CYPs, VKORC1, NAT2, DPYD and CHST3 of Five Ethnic Minorities in Heilongjiang Province, Northeast China.

Pharmacogenomics And Personalized Medicine
Zhang, Tingting T; Li, Qiuyan Q; Dong, Bonan B; Liang, Xiao X; Jia, Mansha M; Bai, Jing J; Yu, Jingcui J; Fu, Songbin S
Publication Date: 2021

Variant appearance in text: rs2359612
PubMed Link: 34876832
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic diversity of 'Very Important Pharmacogenes' in two South-Asian populations.

Peerj
Bharti, Neeraj N; Banerjee, Ruma R; Achalere, Archana A; Kasibhatla, Sunitha Manjari SM; Joshi, Rajendra R
Publication Date: 2021

Variant appearance in text: rs2359612
PubMed Link: 34824904
Variant Present in the following documents:
  • Main text
  • peerj-09-12294.pdf
View BVdb publication page



Machine Learning for Prediction of Stable Warfarin Dose in US Latinos and Latin Americans.

Frontiers In Pharmacology
Steiner, Heidi E HE; Giles, Jason B JB; Patterson, Hayley Knight HK; Feng, Jianglin J; El Rouby, Nihal N; Claudio, Karla K; Marcatto, Leiliane Rodrigues LR; Tavares, Leticia Camargo LC; Galvez, Jubby Marcela JM; Calderon-Ospina, Carlos-Alberto CA; Sun, Xiaoxiao X; Hutz, Mara H MH; Scott, Stuart A SA; Cavallari, Larisa H LH; Fonseca-Mendoza, Dora Janeth DJ; Duconge, Jorge J; Botton, Mariana Rodrigues MR; Santos, Paulo Caleb Junior Lima PCJL; Karnes, Jason H JH
Publication Date: 2021

Variant appearance in text: rs2359612
PubMed Link: 34776967
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations.

Clinical And Translational Science
El Rouby, Nihal N; Shahin, Mohamed H MH; Bader, Loulia L; Khalifa, Sherief I SI; Elewa, Hazem H
Publication Date: 2022-02

Variant appearance in text: rs2359612
PubMed Link: 34729928
Variant Present in the following documents:
  • Main text
  • CTS-15-558.pdf
View BVdb publication page



Gene variants of coagulation related proteins that interact with SARS-CoV-2.

Plos Computational Biology
Holcomb, David D; Alexaki, Aikaterini A; Hernandez, Nancy N; Hunt, Ryan R; Laurie, Kyle K; Kames, Jacob J; Hamasaki-Katagiri, Nobuko N; Komar, Anton A AA; DiCuccio, Michael M; Kimchi-Sarfaty, Chava C
Publication Date: 2021-03

Variant appearance in text: VKORC1: 283+837T>C
PubMed Link: 33730015
Variant Present in the following documents:
  • Main text
  • pcbi.1008805.s002.xlsx, sheet 1
View BVdb publication page



Variation in VKORC1 Is Associated with Vascular Dementia.

Journal Of Alzheimer'S Disease : Jad
Mur, Jure J; McCartney, Daniel L DL; Chasman, Daniel I DI; Visscher, Peter M PM; Muniz-Terrera, Graciela G; Cox, Simon R SR; Russ, Tom C TC; Marioni, Riccardo E RE
Publication Date: 2021

Variant appearance in text: rs2359612
PubMed Link: 33682710
Variant Present in the following documents:
  • Main text
  • jad-80-jad201256.pdf
View BVdb publication page



Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon.

Pharmacogenomics And Personalized Medicine
Fernandes, Marianne Rodrigues MR; Rodrigues, Juliana Carla Gomes JCG; Maroñas, Olalla O; Latorre-Pellicer, Ana A; Cruz, Raquel R; Guerreiro, João Farias JF; Burbano, Rommel Mario Rodriguez RMR; de Assumpção, Paulo Pimentel PP; Ribeiro-Dos-Santos, Andrea A; Dos Santos, Sidney Emanuel Batista SEB; Carracedo, Angel A; Dos Santos, Ney Pereira Carneiro NPC
Publication Date: 2021

Variant appearance in text: rs2359612
PubMed Link: 33519226
Variant Present in the following documents:
  • Main text
  • pgpm-14-117.pdf
View BVdb publication page



Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2.

Biorxiv : The Preprint Server For Biology
Holcomb, David D; Alexaki, Aikaterini A; Hernandez, Nancy N; Laurie, Kyle K; Kames, Jacob J; Hamasaki-Katagiri, Nobuko N; Komar, Anton A AA; DiCuccio, Michael M; Kimchi-Sarfaty, Chava C
Publication Date: 2020-09-18

Variant appearance in text: VKORC1: 283+837T>C
PubMed Link: 32935103
Variant Present in the following documents:
  • Main text
View BVdb publication page



Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing.

Clinical Pharmacokinetics
Yin, Anyue A; Ettaieb, Madeleine H T MHT; Swen, Jesse J JJ; van Deun, Liselotte L; Kerkhofs, Thomas M A TMA; van der Straaten, Robert J H M RJHM; Corssmit, Eleonora P M EPM; Gelderblom, Hans H; Kerstens, Michiel N MN; Feelders, Richard A RA; Eekhoff, Marelise M; Timmers, Henri J L M HJLM; D'Avolio, Antonio A; Cusato, Jessica J; Guchelaar, Henk-Jan HJ; Haak, Harm R HR; Moes, Dirk Jan A R DJAR
Publication Date: 2021-01

Variant appearance in text: rs2359612
PubMed Link: 32607875
Variant Present in the following documents:
  • 40262_2020_913_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Temporal Trends and Familial Clustering of Ideal Cardiovascular Health in Parents and Offspring Over the Life Course: An Investigation Using The Framingham Heart Study.

Journal Of The American Heart Association
Muchira, James M JM; Gona, Philimon N PN; Mogos, Mulubrhan F MF; Stuart-Shor, Eileen E; Leveille, Suzanne G SG; Piano, Mariann R MR; Hayman, Laura L LL
Publication Date: 2020-06-16

Variant appearance in text: rs2359612
PubMed Link: 32486880
Variant Present in the following documents:
  • Main text
  • JAH3-9-e016292.pdf
View BVdb publication page



Role of Genetic Variations in the Hepatic Handling of Drugs.

International Journal Of Molecular Sciences
Marin, Jose J G JJG; Serrano, Maria A MA; Monte, Maria J MJ; Sanchez-Martin, Anabel A; Temprano, Alvaro G AG; Briz, Oscar O; Romero, Marta R MR
Publication Date: 2020-04-20

Variant appearance in text: rs2359612
PubMed Link: 32326111
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide analyses disclose the distinctive HLA architecture and the pharmacogenetic landscape of the Somali population.

Scientific Reports
Ali, Abshir A AA; Aalto, Mikko M; Jonasson, Jon J; Osman, Abdimajid A
Publication Date: 2020-03-27

Variant appearance in text: rs2359612
PubMed Link: 32221414
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_62645.pdf
View BVdb publication page



Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.

Plos One
Ahsan, Tamim T; Urmi, Nusrat Jahan NJ; Sajib, Abu Ashfaqur AA
Publication Date: 2020

Variant appearance in text: rs2359612
PubMed Link: 31971968
Variant Present in the following documents:
  • Main text
  • pone.0228000.pdf
View BVdb publication page



Genetic Factors Influencing Warfarin Dose in Black-African Patients: A Systematic Review and Meta-Analysis.

Clinical Pharmacology And Therapeutics
Asiimwe, Innocent G IG; Zhang, Eunice J EJ; Osanlou, Rostam R; Krause, Amanda A; Dillon, Chrisly C; Suarez-Kurtz, Guilherme G; Zhang, Honghong H; Perini, Jamila A JA; Renta, Jessicca Y JY; Duconge, Jorge J; Cavallari, Larisa H LH; Marcatto, Leiliane R LR; Beasly, Mark T MT; Perera, Minoli A MA; Limdi, Nita A NA; Santos, Paulo C J L PCJL; Kimmel, Stephen E SE; Lubitz, Steven A SA; Scott, Stuart A SA; Kawai, Vivian K VK; Jorgensen, Andrea L AL; Pirmohamed, Munir M
Publication Date: 2020-06

Variant appearance in text: rs2359612
PubMed Link: 31869433
Variant Present in the following documents:
  • Main text
View BVdb publication page



Introducing the first whole genomes of nationals from the United Arab Emirates.

Scientific Reports
AlSafar, Habiba S HS; Al-Ali, Mariam M; Elbait, Gihan Daw GD; Al-Maini, Mustafa H MH; Ruta, Dymitr D; Peramo, Braulio B; Henschel, Andreas A; Tay, Guan K GK
Publication Date: 2019-10-11

Variant appearance in text: rs2359612
PubMed Link: 31604968
Variant Present in the following documents:
  • 41598_2019_50876_MOESM1_ESM.xlsx, sheet 1
  • 41598_2019_50876_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



Clinical Model for Predicting Warfarin Sensitivity.

Scientific Reports
Ma, Zhiyuan Z; Cheng, Gang G; Wang, Ping P; Khalighi, Bahar B; Khalighi, Koroush K
Publication Date: 2019-09-06

Variant appearance in text: rs2359612
PubMed Link: 31492893
Variant Present in the following documents:
  • Main text
  • 41598_2019_Article_49329.pdf
View BVdb publication page



Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases.

Toxicology And Applied Pharmacology
Kosnik, Marissa B MB; Reif, David M DM
Publication Date: 2019-09-15

Variant appearance in text: rs2359612
PubMed Link: 31323264
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effect of gene-gene and gene-environment interaction on the risk of first-ever stroke and poststroke death.

Molecular Genetics & Genomic Medicine
Feng, Congrui C; Yang, Yunyun Y; Yang, Shujun S; Tu, Xin X; Wang, Yibo Y; Song, Yiqing Y; Hui, Rutai R; Zhang, Weili W
Publication Date: 2019-08

Variant appearance in text: rs2359612
PubMed Link: 31293107
Variant Present in the following documents:
  • Main text
View BVdb publication page



VKORC1 variants as significant predictors of warfarin dose in Emiratis.

Pharmacogenomics And Personalized Medicine
Al-Mahayri, Zeina N ZN; Al Jaibeji, Hayat S HS; Saab, Yolande Y; Soliman, Karem K; Al-Gazali, Lihadh L; Patrinos, George P GP; Ali, Bassam R BR
Publication Date: 2019

Variant appearance in text: rs2359612
PubMed Link: 31114289
Variant Present in the following documents:
  • Main text
  • pgpm-12-47.pdf
View BVdb publication page



Value of VKORC1 (-1639G>A) rs9923231 genotyping in predicting warfarin dose: A replication study in South Indian population.

Indian Heart Journal
Harikrishnan, S S; Koshy, Linda L; Subramanian, Ram R; Sanjay, G G; Vineeth, C P CP; Nair, A Jayakumaran AJ; Nair, G M GM; Sudhakaran, P R PR
Publication Date: 2018-12

Variant appearance in text: rs2359612
PubMed Link: 30595241
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Pharmacogenetics of warfarin dosing in patients of African and European ancestry.

Pharmacogenomics
Shendre, Aditi A; Dillon, Chrisly C; Limdi, Nita A NA
Publication Date: 2018-11

Variant appearance in text: rs2359612
PubMed Link: 30345882
Variant Present in the following documents:
  • Main text
View BVdb publication page



Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs2359612
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
View BVdb publication page



Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans.

Genome Medicine
Gottlieb, Assaf A; Daneshjou, Roxana R; DeGorter, Marianne M; Bourgeois, Stephane S; Svensson, Peter J PJ; Wadelius, Mia M; Deloukas, Panos P; Montgomery, Stephen B SB; Altman, Russ B RB
Publication Date: 2017-11-24

Variant appearance in text: rs2359612
PubMed Link: 29178968
Variant Present in the following documents:
  • Main text
  • 13073_2017_Article_495.pdf
View BVdb publication page



Establishing multiple omics baselines for three Southeast Asian populations in the Singapore Integrative Omics Study.

Nature Communications
Saw, Woei-Yuh WY; Tantoso, Erwin E; Begum, Husna H; Zhou, Lihan L; Zou, Ruiyang R; He, Cheng C; Chan, Sze Ling SL; Tan, Linda Wei-Lin LW; Wong, Lai-Ping LP; Xu, Wenting W; Moong, Don Kyin Nwe DKN; Lim, Yenly Y; Li, Bowen B; Pillai, Nisha Esakimuthu NE; Peterson, Trevor A TA; Bielawny, Tomasz T; Meikle, Peter J PJ; Mundra, Piyushkumar A PA; Lim, Wei-Yen WY; Luo, Ma M; Chia, Kee-Seng KS; Ong, Rick Twee-Hee RT; Brunham, Liam R LR; Khor, Chiea-Chuen CC; Too, Heng Phon HP; Soong, Richie R; Wenk, Markus R MR; Little, Peter P; Teo, Yik-Ying YY
Publication Date: 2017-09-21

Variant appearance in text: rs2359612
PubMed Link: 28935855
Variant Present in the following documents:
  • Main text
View BVdb publication page



Increasing the power of meta-analysis of genome-wide association studies to detect heterogeneous effects.

Bioinformatics (Oxford, England)
Lee, C H CH; Eskin, E E; Han, B B
Publication Date: 2017-07-15

Variant appearance in text: rs2359612
PubMed Link: 28881976
Variant Present in the following documents:
  • Main text
  • btx242.pdf
View BVdb publication page



Warfarin-induced life-threatening bleeding associated with a CYP3A4 loss-of-function mutation in an acute limb ischemia patient: Case report and review of the literature.

Experimental And Therapeutic Medicine
Ma, Xiao-Wei XW; Hao, Chang-Ning CN; Gu, Zhi-Chun ZC; Ye, Meng M; Li, Min M; Zhang, Lan L
Publication Date: 2017-08

Variant appearance in text: rs2359612
PubMed Link: 28810573
Variant Present in the following documents:
  • Main text
View BVdb publication page



Exploring public genomics data for population pharmacogenomics.

Plos One
Lakiotaki, Kleanthi K; Kanterakis, Alexandros A; Kartsaki, Evgenia E; Katsila, Theodora T; Patrinos, George P GP; Potamias, George G
Publication Date: 2017

Variant appearance in text: rs2359612
PubMed Link: 28771511
Variant Present in the following documents:
  • Main text
  • pone.0182138.pdf
View BVdb publication page



STRATEGIES FOR EQUITABLE PHARMACOGENOMIC-GUIDED WARFARIN DOSING AMONG EUROPEAN AND AFRICAN AMERICAN INDIVIDUALS IN A CLINICAL POPULATION.

Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing
Wiley, Laura K LK; Vanhouten, Jacob P JP; Samuels, David C DC; Aldrich, Melinda C MC; Roden, Dan M DM; Peterson, Josh F JF; Denny, Joshua C JC
Publication Date: 2017

Variant appearance in text: rs2359612
PubMed Link: 27897005
Variant Present in the following documents:
  • Main text
View BVdb publication page



G-1639A but Not C1173T VKORC1 Gene Polymorphism Is Related to Ischemic Stroke and Its Various Risk Factors in Ukrainian Population.

Biomed Research International
Dubovyk, Yevhen I YI; Harbuzova, Viktoriia Yu VY; Ataman, Alexander V AV
Publication Date: 2016

Variant appearance in text: rs2359612
PubMed Link: 27703968
Variant Present in the following documents:
  • BMRI2016-1298198.pdf
View BVdb publication page



Genetic determinants of variability in warfarin response after the dose-titration phase.

Pharmacogenetics And Genomics
Iwuchukwu, Otito F OF; Ramirez, Andrea H AH; Shi, Yaping Y; Bowton, Erica A EA; Kawai, Vivian K VK; Schildcrout, Jonathan S JS; Roden, Dan M DM; Denny, Joshua C JC; Stein, C Michael CM
Publication Date: 2016-11

Variant appearance in text: rs2359612
PubMed Link: 27632229
Variant Present in the following documents:
  • Main text
View BVdb publication page



VKORC1 and CD-14 genetic polymorphisms associate with susceptibility to cardiovascular and cerebrovascular diseases.

International Journal Of Clinical And Experimental Medicine
Du, Jian J; Zhang, Zhiguo Z; Ge, Yuanyuan Y; Zhen, Juan J; Leng, Jiyan J; Wang, Jianmeng J
Publication Date: 2015

Variant appearance in text: rs2359612
PubMed Link: 26884960
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.

Pharmacogenetics And Genomics
Chan, Sze Ling SL; Samaranayake, Nilakshi N; Ross, Colin J D CJ; Toh, Meng Tiak MT; Carleton, Bruce B; Hayden, Michael R MR; Teo, Yik Ying YY; Dissanayake, Vajira H W VH; Brunham, Liam R LR
Publication Date: 2016-01

Variant appearance in text: rs2359612
PubMed Link: 26444257
Variant Present in the following documents:
  • Main text
  • fpc-26-28.pdf
View BVdb publication page



Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.

Mayo Clinic Proceedings
Kaufman, Amy L AL; Spitz, Jared J; Jacobs, Michael M; Sorrentino, Matthew M; Yuen, Shennin S; Danahey, Keith K; Saner, Donald D; Klein, Teri E TE; Altman, Russ B RB; Ratain, Mark J MJ; O'Donnell, Peter H PH
Publication Date: 2015-06

Variant appearance in text: rs2359612
PubMed Link: 26046407
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Affymetrix DMET Plus platform reveals unique distribution of ADME-related variants in ethnic Arabs.

Disease Markers
Wakil, Salma M SM; Nguyen, Cao C; Muiya, Nzioka P NP; Andres, Editha E; Lykowska-Tarnowska, Agnieszka A; Baz, Batoul B; Tahir, Asma I AI; Meyer, Brian F BF; Morahan, Grant G; Dzimiri, Nduna N
Publication Date: 2015

Variant appearance in text: rs2359612
PubMed Link: 25802476
Variant Present in the following documents:
  • 542543.f1.xlsx, sheet 1
View BVdb publication page



Measures of exposure impact genetic association studies: an example in vitamin K levels and VKORC1.

Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing
Crawford, Dana C DC; Brown-Gentry, Kristin K; Rieder, Mark J MJ
Publication Date: 2015

Variant appearance in text: rs2359612
PubMed Link: 25592578
Variant Present in the following documents:
  • Main text
View BVdb publication page



The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

Toxicology Reports
Simon, B R BR; Wilson, M J MJ; Wickliffe, J K JK
Publication Date: 2014

Variant appearance in text: rs2359612
PubMed Link: 25126521
Variant Present in the following documents:
  • mmc1.xls, sheet 1
View BVdb publication page



Screening for 392 polymorphisms in 141 pharmacogenes.

Biomedical Reports
Kim, Jason Yongha JY; Cheong, Hyun Sub HS; Park, Tae-Joon TJ; Shin, Hee Jung HJ; Seo, Doo Won DW; Na, Han Sung HS; Chung, Myeon Woo MW; Shin, Hyoung Doo HD
Publication Date: 2014-07

Variant appearance in text: rs2359612
PubMed Link: 24944790
Variant Present in the following documents:
  • Main text
View BVdb publication page



Inter and intra ethnic variation of vitamin K epoxide reductase complex and cytochrome P450 4F2 genetic polymorphisms and their prevalence in South Indian population.

Indian Journal Of Human Genetics
Kumar, Dhakchinamoorthi Krishna DK; Shewade, Deepak Gopal DG; Manjunath, Sajjanavar S; Ushakiran, Prayaga P; Reneega, Gangadharan G; Adithan, Chandrasekaran C
Publication Date: 2013-07

Variant appearance in text: rs2359612
PubMed Link: 24339542
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of functional VKORC1 promoter polymorphism with occurrence and clinical aspects of ischemic stroke in a Greek population.

Disease Markers
Ragia, Georgia G; Marousi, Stella S; Ellul, John J; Manolopoulos, Vangelis G VG; Tavridou, Anna A
Publication Date: 2013

Variant appearance in text: rs2359612
PubMed Link: 24288433
Variant Present in the following documents:
  • Main text
  • DM35-06-769574.pdf
View BVdb publication page



Pharmacogenetics in cardiovascular disease: the challenge of moving from promise to realization: concepts discussed at the Canadian Network and Centre for Trials Internationally Network Conference (CANNeCTIN), June 2009.

Clinical Cardiology
Joseph, Philip G PG; Pare, Guillaume G; Ross, Stephanie S; Roberts, Robert R; Anand, Sonia S SS
Publication Date: 2014-01

Variant appearance in text: rs2359612
PubMed Link: 24105892
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk.

Jama Neurology
Moskvina, Valentina V; Harold, Denise D; Russo, GianCarlo G; Vedernikov, Alexey A; Sharma, Manu M; Saad, Mohamed M; Holmans, Peter P; Bras, Jose M JM; Bettella, Francesco F; Keller, Margaux F MF; Nicolaou, Nayia N; Simón-Sánchez, Javier J; Gibbs, J Raphael JR; Schulte, Claudia C; Durr, Alexandra A; Guerreiro, Rita R; Hernandez, Dena D; Brice, Alexis A; Stefánsson, Hreinn H; Majamaa, Kari K; Gasser, Thomas T; Heutink, Peter P; Wood, Nick N; Martinez, Maria M; Singleton, Andrew B AB; Nalls, Michael A MA; Hardy, John J; Owen, Michael J MJ; O'Donovan, Michael C MC; Williams, Julie J; Morris, Huw R HR; Williams, Nigel M NM; ,
Publication Date: 2013-10

Variant appearance in text: rs2359612
PubMed Link: 23921447
Variant Present in the following documents:
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Warfarin pharmacogenomics in children.

Pediatric Blood & Cancer
Vear, Susan I SI; Stein, C Michael CM; Ho, Richard H RH
Publication Date: 2013-09

Variant appearance in text: rs2359612
PubMed Link: 23682017
Variant Present in the following documents:
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Genetic variation and haplotype structure of the gene Vitamin K epoxide reductase complex, subunit 1 in the Tamilian population.

Journal Of Pharmacology & Pharmacotherapeutics
Kumar, Dhakchinamoorthi Krishna DK; Shewade, Deepak Gopal DG; Surendiran, Adithan A; Adithan, Chandrasekaran C
Publication Date: 2013-01

Variant appearance in text: rs2359612
PubMed Link: 23662025
Variant Present in the following documents:
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Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans.

Plos One
Patillon, Blandine B; Luisi, Pierre P; Blanché, Hélène H; Patin, Etienne E; Cann, Howard M HM; Génin, Emmanuelle E; Sabbagh, Audrey A
Publication Date: 2012

Variant appearance in text: rs2359612
PubMed Link: 23285254
Variant Present in the following documents:
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Impact of genetic polymorphisms on clinical response to antithrombotics.

Pharmacogenomics And Personalized Medicine
Lanham, Kena J KJ; Oestreich, Julie H JH; Dunn, Steven P SP; Steinhubl, Steven R SR
Publication Date: 2010

Variant appearance in text: rs2359612
PubMed Link: 23226045
Variant Present in the following documents:
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Personalized approach of medication by indirect anticoagulants tailored to the patient-Russian context: what are the prospects?

The Epma Journal
Belozerceva, Liliya Alexandrovna LA; Voronina, Elena Nikolaevna EN; Kokh, Natalia Viktorovna NV; Tsvetovskay, Galina Alexandrovna GA; Momot, Andrei Pavlovich AP; Lifshits, Galina Israilevna GI; Filipenko, Maxim Leonidovich ML; Shevela, Andrei Ivanovich AI; Vlasov, Valentin Viktorovich VV
Publication Date: 2012-09-27

Variant appearance in text: rs2359612
PubMed Link: 23016735
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Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysis.

Plos One
Jorgensen, Andrea L AL; FitzGerald, Richard J RJ; Oyee, James J; Pirmohamed, Munir M; Williamson, Paula R PR
Publication Date: 2012

Variant appearance in text: rs2359612
PubMed Link: 22952875
Variant Present in the following documents:
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Liver expression quantitative trait loci: a foundation for pharmacogenomic research.

Frontiers In Genetics
Glubb, Dylan M DM; Dholakia, Neepa N; Innocenti, Federico F
Publication Date: 2012

Variant appearance in text: rs2359612
PubMed Link: 22912647
Variant Present in the following documents:
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