Constructing a polygenic risk score for childhood obesity using functional data analysis.
Econometrics And Statistics
Craig, Sarah J C SJC; Kenney, Ana M AM; Lin, Junli J; Paul, Ian M IM; Birch, Leann L LL; Savage, Jennifer S JS; Marini, Michele E ME; Chiaromonte, Francesca F; Reimherr, Matthew L ML; Makova, Kateryna D KD
Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci.
Elife
Hammond, Reza K RK; Pahl, Matthew C MC; Su, Chun C; Cousminer, Diana L DL; Leonard, Michelle E ME; Lu, Sumei S; Doege, Claudia A CA; Wagley, Yadav Y; Hodge, Kenyaita M KM; Lasconi, Chiara C; Johnson, Matthew E ME; Pippin, James A JA; Hankenson, Kurt D KD; Leibel, Rudolph L RL; Chesi, Alessandra A; Wells, Andrew D AD; Grant, Struan Fa SF
Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci.
Elife
Hammond, Reza K RK; Pahl, Matthew C MC; Su, Chun C; Cousminer, Diana L DL; Leonard, Michelle E ME; Lu, Sumei S; Doege, Claudia A CA; Wagley, Yadav Y; Hodge, Kenyaita M KM; Lasconi, Chiara C; Johnson, Matthew E ME; Pippin, James A JA; Hankenson, Kurt D KD; Leibel, Rudolph L RL; Chesi, Alessandra A; Wells, Andrew D AD; Grant, Struan Fa SF
Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses.
Bmj (Clinical Research Ed.)
Sun, Yi-Qian YQ; Burgess, Stephen S; Staley, James R JR; Wood, Angela M AM; Bell, Steven S; Kaptoge, Stephen K SK; Guo, Qi Q; Bolton, Thomas R TR; Mason, Amy M AM; Butterworth, Adam S AS; Di Angelantonio, Emanuele E; Vie, Gunnhild Å GÅ; Bjørngaard, Johan H JH; Kinge, Jonas Minet JM; Chen, Yue Y; Mai, Xiao-Mei XM
Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits.
American Journal Of Human Genetics
Freund, Malika Kumar MK; Burch, Kathryn S KS; Shi, Huwenbo H; Mancuso, Nicholas N; Kichaev, Gleb G; Garske, Kristina M KM; Pan, David Z DZ; Miao, Zong Z; Mohlke, Karen L KL; Laakso, Markku M; Pajukanta, Päivi P; Pasaniuc, Bogdan B; Arboleda, Valerie A VA
Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study.
Bmj (Clinical Research Ed.)
Wootton, Robyn E RE; Lawn, Rebecca B RB; Millard, Louise A C LAC; Davies, Neil M NM; Taylor, Amy E AE; Munafò, Marcus R MR; Timpson, Nicholas J NJ; Davis, Oliver S P OSP; Davey Smith, George G; Haworth, Claire M A CMA
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses.
Plos Genetics
Baranski, Thomas J TJ; Kraja, Aldi T AT; Fink, Jill L JL; Feitosa, Mary M; Lenzini, Petra A PA; Borecki, Ingrid B IB; Liu, Ching-Ti CT; Cupples, L Adrienne LA; North, Kari E KE; Province, Michael A MA
Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries.
Diabetologia
Li, Sherly X SX; Imamura, Fumiaki F; Schulze, Matthias B MB; Zheng, Jusheng J; Ye, Zheng Z; Agudo, Antonio A; Ardanaz, Eva E; Aune, Dagfinn D; Boeing, Heiner H; Dorronsoro, Miren M; Dow, Courtney C; Fagherazzi, Guy G; Grioni, Sara S; Gunter, Marc J MJ; Huerta, José María JM; Ibsen, Daniel B DB; Jakobsen, Marianne Uhre MU; Kaaks, Rudolf R; Key, Timothy J TJ; Khaw, Kay-Tee KT; Kyrø, Cecilie C; Mancini, Francesca Romana FR; Molina-Portillo, Elena E; Murphy, Neil N; Nilsson, Peter M PM; Onland-Moret, N Charlotte NC; Palli, Domenico D; Panico, Salvatore S; Poveda, Alaitz A; Quirós, J Ramón JR; Ricceri, Fulvio F; Sluijs, Ivonne I; Spijkerman, Annemieke M W AMW; Tjonneland, Anne A; Tumino, Rosario R; Winkvist, Anna A; Langenberg, Claudia C; Sharp, Stephen J SJ; Riboli, Elio E; Scott, Robert A RA; Forouhi, Nita G NG; Wareham, Nicholas J NJ
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.
Plos Medicine
Noyce, Alastair J AJ; Kia, Demis A DA; Hemani, Gibran G; Nicolas, Aude A; Price, T Ryan TR; De Pablo-Fernandez, Eduardo E; Haycock, Philip C PC; Lewis, Patrick A PA; Foltynie, Thomas T; Davey Smith, George G; , ; Schrag, Anette A; Lees, Andrew J AJ; Hardy, John J; Singleton, Andrew A; Nalls, Mike A MA; Pearce, Neil N; Lawlor, Debbie A DA; Wood, Nicholas W NW
Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity.
Molecular Metabolism
Keller, Maria M; Hopp, Lydia L; Liu, Xuanshi X; Wohland, Tobias T; Rohde, Kerstin K; Cancello, Raffaella R; Klös, Matthias M; Bacos, Karl K; Kern, Matthias M; Eichelmann, Fabian F; Dietrich, Arne A; Schön, Michael R MR; Gärtner, Daniel D; Lohmann, Tobias T; Dreßler, Miriam M; Stumvoll, Michael M; Kovacs, Peter P; DiBlasio, Anna-Maria AM; Ling, Charlotte C; Binder, Hans H; Blüher, Matthias M; Böttcher, Yvonne Y
Appetitive traits as behavioural pathways in genetic susceptibility to obesity: a population-based cross-sectional study.
Scientific Reports
Konttinen, Hanna H; Llewellyn, Clare C; Wardle, Jane J; Silventoinen, Karri K; Joensuu, Anni A; Männistö, Satu S; Salomaa, Veikko V; Jousilahti, Pekka P; Kaprio, Jaakko J; Perola, Markus M; Haukkala, Ari A
Genetic studies of body mass index yield new insights for obesity biology.
Nature
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