FTO c.46-27214G>A

Variant ID: 16-53816838-G-A

NM_001080432.2(FTO):c.46-27214G>A

This variant was identified in 23 publications

View GRCh38 version.




Publications:


FTO Common Obesity SNPs Interact with Actionable Environmental Factors: Physical Activity, Sugar-Sweetened Beverages and Wine Consumption.

Nutrients
Chermon, Danyel D; Birk, Ruth R
Publication Date: 2022-10-09

Variant appearance in text: rs9935401
PubMed Link: 36235854
Variant Present in the following documents:
  • Main text
  • nutrients-14-04202.pdf
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Genetic Polymorphisms, Mediterranean Diet and Microbiota-Associated Urolithin Metabotypes can Predict Obesity in Childhood-Adolescence.

Scientific Reports
Cortés-Martín, Adrián A; Colmenarejo, Gonzalo G; Selma, María Victoria MV; Espín, Juan Carlos JC
Publication Date: 2020-05-12

Variant appearance in text: rs9935401
PubMed Link: 32398726
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_64833.pdf
  • 41598_2020_64833_MOESM1_ESM.pdf
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Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies.

Scientific Reports
Ran, Shu S; Jiang, Zi-Xuan ZX; He, Xiao X; Liu, Yu Y; Zhang, Yu-Xue YX; Zhang, Lei L; Pei, Yu-Fang YF; Zhang, Meng M; Hai, Rong R; Gu, Gui-Shan GS; Liu, Bao-Lin BL; Tian, Qing Q; Zhang, Yong-Hong YH; Wang, Jing-Yu JY; Deng, Hong-Wen HW
Publication Date: 2020-03-19

Variant appearance in text: rs9935401
PubMed Link: 32193455
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_61406.pdf
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Physical Activity Might Reduce the Adverse Impacts of the FTO Gene Variant rs3751812 on the Body Mass Index of Adults in Taiwan.

Genes
Liaw, Yi-Ching YC; Liaw, Yung-Po YP; Lan, Tsuo-Hung TH
Publication Date: 2019-05-09

Variant appearance in text: rs9935401
PubMed Link: 31075924
Variant Present in the following documents:
  • Main text
  • genes-10-00354.pdf
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Associations between Single Nucleotide Polymorphisms and Total Energy, Carbohydrate, and Fat Intakes: A Systematic Review.

Advances In Nutrition (Bethesda, Md.)
Drabsch, Theresa T; Gatzemeier, Jennifer J; Pfadenhauer, Lisa L; Hauner, Hans H; Holzapfel, Christina C
Publication Date: 2018-07-01

Variant appearance in text: rs9935401
PubMed Link: 30032228
Variant Present in the following documents:
  • Main text
  • nmy024.pdf
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Assessing the Causality Factors in the Association between (Abdominal) Obesity and Physical Activity among the Newfoundland Population-A Mendelian Randomization Analysis.

Genetics & Epigenetics
Barning, Frank F; Abarin, Taraneh T
Publication Date: 2016

Variant appearance in text: rs9935401
PubMed Link: 27478388
Variant Present in the following documents:
  • Main text
  • geg-8-2016-015.pdf
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Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.

Cancer Epidemiology
Yang, Baiyu B; Thrift, Aaron P AP; Figueiredo, Jane C JC; Jenkins, Mark A MA; Schumacher, Fredrick R FR; Conti, David V DV; Lin, Yi Y; Win, Aung Ko AK; Limburg, Paul J PJ; Berndt, Sonja I SI; Brenner, Hermann H; Chan, Andrew T AT; Chang-Claude, Jenny J; Hoffmeister, Michael M; Hudson, Thomas J TJ; Marchand, Loïc Le LL; Newcomb, Polly A PA; Slattery, Martha L ML; White, Emily E; Peters, Ulrike U; Casey, Graham G; Campbell, Peter T PT
Publication Date: 2016-10

Variant appearance in text: rs9935401
PubMed Link: 27449576
Variant Present in the following documents:
  • Main text
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Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools.

Molecular Metabolism
Teo, Adrian Kee Keong AK; Gupta, Manoj K MK; Doria, Alessandro A; Kulkarni, Rohit N RN
Publication Date: 2015-09

Variant appearance in text: rs9935401
PubMed Link: 26413465
Variant Present in the following documents:
  • Main text
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Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults.

Obesity Reviews : An Official Journal Of The International Association For The Study Of Obesity
Zimmermann, E E; Ängquist, L H LH; Mirza, S S SS; Zhao, J H JH; Chasman, D I DI; Fischer, K K; Qi, Q Q; Smith, A V AV; Thinggaard, M M; Jarczok, M N MN; Nalls, M A MA; Trompet, S S; Timpson, N J NJ; Schmidt, B B; Jackson, A U AU; Lyytikäinen, L P LP; Verweij, N N; Mueller-Nurasyid, M M; Vikström, M M; Marques-Vidal, P P; Wong, A A; Meidtner, K K; Middelberg, R P RP; Strawbridge, R J RJ; Christiansen, L L; , ; Kyvik, K O KO; Hamsten, A A; Jääskeläinen, T T; Tjønneland, A A; Eriksson, J G JG; Whitfield, J B JB; Boeing, H H; Hardy, R R; Vollenweider, P P; Leander, K K; Peters, A A; van der Harst, P P; Kumari, M M; Lehtimäki, T T; Meirhaeghe, A A; Tuomilehto, J J; Jöckel, K-H KH; Ben-Shlomo, Y Y; Sattar, N N; Baumeister, S E SE; Smith, G Davey GD; Casas, J P JP; Houston, D K DK; März, W W; Christensen, K K; Gudnason, V V; Hu, F B FB; Metspalu, A A; Ridker, P M PM; Wareham, N J NJ; Loos, R J F RJF; Tiemeier, H H; Sonestedt, E E; Sørensen, T I A TIA
Publication Date: 2015-04

Variant appearance in text: rs9935401
PubMed Link: 25752329
Variant Present in the following documents:
  • Main text
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Effect of FTO Gene and Physical Activity Interaction on Trunk Fat Percentage Among the Newfoundland Population.

Genetics & Epigenetics
Payne, Anthony A; Cahill, Farrell F; Sun, Guang G; Loredo-Osti, J Concepción JC; Abarin, Taraneh T
Publication Date: 2014

Variant appearance in text: rs9935401
PubMed Link: 25512711
Variant Present in the following documents:
  • Main text
  • geg-6-2014-021.pdf
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Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs9935401
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
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Exploring genetic variants predisposing to diabetes mellitus and their association with indicators of socioeconomic status.

Bmc Public Health
Schmidt, Börge B; Dragano, Nico N; Scherag, André A; Pechlivanis, Sonali S; Hoffmann, Per P; Nöthen, Markus M MM; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S
Publication Date: 2014-06-16

Variant appearance in text: rs9935401
PubMed Link: 24935819
Variant Present in the following documents:
  • Main text
  • 1471-2458-14-609.pdf
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Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

Plos One
Tan, Li-Jun LJ; Zhu, Hu H; He, Hao H; Wu, Ke-Hao KH; Li, Jian J; Chen, Xiang-Ding XD; Zhang, Ji-Gang JG; Shen, Hui H; Tian, Qing Q; Krousel-Wood, Marie M; Papasian, Christopher J CJ; Bouchard, Claude C; Pérusse, Louis L; Deng, Hong-Wen HW
Publication Date: 2014

Variant appearance in text: rs9935401
PubMed Link: 24879436
Variant Present in the following documents:
  • Main text
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Influence of FTO variants on obesity, inflammation and cardiovascular disease risk biomarkers in Spanish children: a case-control multicentre study.

Bmc Medical Genetics
Olza, Josune J; Ruperez, Azahara I AI; Gil-Campos, Mercedes M; Leis, Rosaura R; Fernandez-Orth, Dietmar D; Tojo, Rafael R; Cañete, Ramon R; Gil, Angel A; Aguilera, Concepcion M CM
Publication Date: 2013-12-01

Variant appearance in text: rs9935401
PubMed Link: 24289790
Variant Present in the following documents:
  • Main text
  • 1471-2350-14-123.pdf
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Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
Apalasamy, Y D YD; Ming, M F MF; Rampal, S S; Bulgiba, A A; Mohamed, Z Z
Publication Date: 2012-12

Variant appearance in text: rs9935401
PubMed Link: 22911346
Variant Present in the following documents:
  • Main text
  • 0100-879X-bjmbr-45-12-1119.pdf
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Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia.

Annals Of Human Genetics
Karns, Rebekah R; Viali, Satupaitea S; Tuitele, John J; Sun, Guangyun G; Cheng, Hong H; Weeks, Daniel E DE; McGarvey, Stephen T ST; Deka, Ranjan R
Publication Date: 2012-01

Variant appearance in text: rs9935401
PubMed Link: 22084931
Variant Present in the following documents:
  • Main text
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A genome-wide association study on obesity and obesity-related traits.

Plos One
Wang, Kai K; Li, Wei-Dong WD; Zhang, Clarence K CK; Wang, Zuoheng Z; Glessner, Joseph T JT; Grant, Struan F A SF; Zhao, Hongyu H; Hakonarson, Hakon H; Price, R Arlen RA
Publication Date: 2011-04-28

Variant appearance in text: rs9935401
PubMed Link: 21552555
Variant Present in the following documents:
  • Main text
  • pone.0018939.pdf
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First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study.

Journal Of Epidemiology And Community Health
Holzapfel, Christina C; Grallert, Harald H; Baumert, Jens J; Thorand, Barbara B; Döring, Angela A; Wichmann, H Erich HE; Hauner, Hans H; Illig, Thomas T; Mielck, Andreas A
Publication Date: 2011-02

Variant appearance in text: rs9935401
PubMed Link: 20628085
Variant Present in the following documents:
  • Main text
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Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years.

Obesity Facts
Rzehak, Peter P; Scherag, André A; Grallert, Harald H; Sausenthaler, Stefanie S; Koletzko, Sibylle S; Bauer, Carl Peter CP; Schaaf, Beate B; von Berg, Andrea A; Berdel, Dietrich D; Borte, Michael M; Herbarth, Olf O; Krämer, Ursula U; Illig, Thomas T; Wichmann, H-Erich HE; Hebebrand, Johannes J; Heinrich, Joachim J; ,
Publication Date: 2010-06

Variant appearance in text: rs9935401
PubMed Link: 20616607
Variant Present in the following documents:
  • Main text
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The ongoing identification of novel obesity genes.

Obesity Facts
Hebebrand, Johannes J
Publication Date: 2010-06

Variant appearance in text: rs9935401
PubMed Link: 20616604
Variant Present in the following documents:
  • Main text
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Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.

Plos One
Zhang, Ge G; Karns, Rebekah R; Narancic, Nina Smolej NS; Sun, Guangyun G; Cheng, Hong H; Missoni, Sasa S; Durakovic, Zijad Z; Rudan, Pavao P; Chakraborty, Ranajit R; Deka, Ranjan R
Publication Date: 2010-04-28

Variant appearance in text: rs9935401
PubMed Link: 20442772
Variant Present in the following documents:
  • Main text
  • pone.0010375.pdf
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Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.

Plos Genetics
Scherag, André A; Dina, Christian C; Hinney, Anke A; Vatin, Vincent V; Scherag, Susann S; Vogel, Carla I G CI; Müller, Timo D TD; Grallert, Harald H; Wichmann, H-Erich HE; Balkau, Beverley B; Heude, Barbara B; Jarvelin, Marjo-Riitta MR; Hartikainen, Anna-Liisa AL; Levy-Marchal, Claire C; Weill, Jacques J; Delplanque, Jérôme J; Körner, Antje A; Kiess, Wieland W; Kovacs, Peter P; Rayner, Nigel W NW; Prokopenko, Inga I; McCarthy, Mark I MI; Schäfer, Helmut H; Jarick, Ivonne I; Boeing, Heiner H; Fisher, Eva E; Reinehr, Thomas T; Heinrich, Joachim J; Rzehak, Peter P; Berdel, Dietrich D; Borte, Michael M; Biebermann, Heike H; Krude, Heiko H; Rosskopf, Dieter D; Rimmbach, Christian C; Rief, Winfried W; Fromme, Tobias T; Klingenspor, Martin M; Schürmann, Annette A; Schulz, Nadja N; Nöthen, Markus M MM; Mühleisen, Thomas W TW; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S; Boes, Tanja T; Illig, Thomas T; Froguel, Philippe P; Hebebrand, Johannes J; Meyre, David D
Publication Date: 2010-04-22

Variant appearance in text: rs9935401
PubMed Link: 20421936
Variant Present in the following documents:
  • Main text
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Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.

International Journal Of Obesity (2005)
Holzapfel, C C; Grallert, H H; Huth, C C; Wahl, S S; Fischer, B B; Döring, A A; Rückert, I M IM; Hinney, A A; Hebebrand, J J; Wichmann, H-E HE; Hauner, H H; Illig, T T; Heid, I M IM
Publication Date: 2010-10

Variant appearance in text: rs9935401
PubMed Link: 20386550
Variant Present in the following documents:
  • Main text
View BVdb publication page