FTO c.965G>A ;(p.R322Q)

Variant ID: 16-53907767-G-A

NM_001080432.2(FTO):c.965G>A;(p.R322Q)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


In silico profiling of nonsynonymous SNPs of fat mass and obesity-associated gene: possible impacts on the treatment of non-alcoholic fatty liver disease.

Lipids In Health And Disease
Patnaik, Damini D; Jena, Atala Bihari AB; Kerry, Rout George RG; Duttaroy, Asim K AK
Publication Date: 2023-01-30

Variant appearance in text: FTO: Arg322Gln; rs745616565
PubMed Link: 36717943
Variant Present in the following documents:
  • Main text
  • 12944_2023_Article_1782.pdf
View BVdb publication page



Comprehensive mutations analyses of FTO (fat mass and obesity-associated gene) and their effects on FTO's substrate binding implicated in obesity.

Frontiers In Nutrition
Kumar, Rakesh R; Ningombam, Somorjit Singh SS; Kumar, Rahul R; Goel, Harsh H; Gogia, Ajay A; Khurana, Sachin S; Deo, S V S SVS; Mathur, Sandeep S; Tanwar, Pranay P
Publication Date: 2022

Variant appearance in text: FTO: R322Q
PubMed Link: 35923209
Variant Present in the following documents:
  • Main text
  • fnut-09-852944.pdf
View BVdb publication page



Analysis of coding variants in the human FTO gene from the gnomAD database.

Plos One
Souza Junior, Mauro Lúcio Ferreira MLF; de Sousa, Jaime Viana JV; Guerreiro, João Farias JF
Publication Date: 2022

Variant appearance in text: FTO: Arg322Gln
PubMed Link: 34990463
Variant Present in the following documents:
  • Main text
  • pone.0248610.pdf
View BVdb publication page



Analysis of coding variants in the human FTO gene from the gnomAD database.

Plos One
Souza Junior, Mauro Lúcio Ferreira MLF; de Sousa, Jaime Viana JV; Guerreiro, João Farias JF
Publication Date: 2022

Variant appearance in text: FTO: Arg322Gln
PubMed Link: 34990463
Variant Present in the following documents:
  • Main text
  • pone.0248610.pdf
View BVdb publication page



FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis.

Oncogene
Ruan, Dan-Yun DY; Li, Ting T; Wang, Ying-Nan YN; Meng, Qi Q; Li, Yang Y; Yu, Kai K; Wang, Min M; Lin, Jin-Fei JF; Luo, Li-Zhi LZ; Wang, De-Shen DS; Lin, Jun-Zhong JZ; Bai, Long L; Liu, Ze-Xian ZX; Zhao, Qi Q; Wu, Xiang-Yuan XY; Ju, Huai-Qiang HQ; Xu, Rui-Hua RH
Publication Date: 2021-08

Variant appearance in text: FTO: R322Q
PubMed Link: 34218271
Variant Present in the following documents:
  • 41388_2021_Article_1916.pdf
View BVdb publication page



FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis.

Oncogene
Ruan, Dan-Yun DY; Li, Ting T; Wang, Ying-Nan YN; Meng, Qi Q; Li, Yang Y; Yu, Kai K; Wang, Min M; Lin, Jin-Fei JF; Luo, Li-Zhi LZ; Wang, De-Shen DS; Lin, Jun-Zhong JZ; Bai, Long L; Liu, Ze-Xian ZX; Zhao, Qi Q; Wu, Xiang-Yuan XY; Ju, Huai-Qiang HQ; Xu, Rui-Hua RH
Publication Date: 2021-08

Variant appearance in text: FTO: R322Q
PubMed Link: 34218271
Variant Present in the following documents:
  • 41388_2021_Article_1916.pdf
View BVdb publication page



Roles of HIF and 2-Oxoglutarate-Dependent Dioxygenases in Controlling Gene Expression in Hypoxia.

Cancers
Frost, Julianty J; Frost, Mark M; Batie, Michael M; Jiang, Hao H; Rocha, Sonia S
Publication Date: 2021-01-19

Variant appearance in text: FTO: 965G>A; R322Q
PubMed Link: 33477877
Variant Present in the following documents:
  • cancers-13-00350-s001.pdf
View BVdb publication page



Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs.

Breast Cancer Research : Bcr
Li, Na N; Rowley, Simone M SM; Thompson, Ella R ER; McInerny, Simone S; Devereux, Lisa L; Amarasinghe, Kaushalya C KC; Zethoven, Magnus M; Lupat, Richard R; Goode, David D; Li, Jason J; Trainer, Alison H AH; Gorringe, Kylie L KL; James, Paul A PA; Campbell, Ian G IG
Publication Date: 2018-01-09

Variant appearance in text: FTO: 965G>A; Arg322Gln
PubMed Link: 29316957
Variant Present in the following documents:
  • 13058_2017_929_MOESM1_ESM.xlsx, sheet 3
View BVdb publication page



Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.

Cell Reports
Giannakis, Marios M; Mu, Xinmeng Jasmine XJ; Shukla, Sachet A SA; Qian, Zhi Rong ZR; Cohen, Ofir O; Nishihara, Reiko R; Bahl, Samira S; Cao, Yin Y; Amin-Mansour, Ali A; Yamauchi, Mai M; Sukawa, Yasutaka Y; Stewart, Chip C; Rosenberg, Mara M; Mima, Kosuke K; Inamura, Kentaro K; Nosho, Katsuhiko K; Nowak, Jonathan A JA; Lawrence, Michael S MS; Giovannucci, Edward L EL; Chan, Andrew T AT; Ng, Kimmie K; Meyerhardt, Jeffrey A JA; Van Allen, Eliezer M EM; Getz, Gad G; Gabriel, Stacey B SB; Lander, Eric S ES; Wu, Catherine J CJ; Fuchs, Charles S CS; Ogino, Shuji S; Garraway, Levi A LA
Publication Date: 2016-04-26

Variant appearance in text: FTO: R322Q
PubMed Link: 27149842
Variant Present in the following documents:
  • mmc2.xlsx, sheet 4
View BVdb publication page



A 680 kb duplication at the FTO locus in a kindred with obesity and a distinct body fat distribution.

European Journal Of Human Genetics : Ejhg
Davies, Robert W RW; Lau, Paulina P; Naing, Thet T; Nikpay, Majid M; Doelle, Heather H; Harper, Mary Ellen ME; Dent, Robert R; McPherson, Ruth R
Publication Date: 2013-12

Variant appearance in text: FTO: R322Q
PubMed Link: 23591406
Variant Present in the following documents:
  • Main text
View BVdb publication page



FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More?

Frontiers In Endocrinology
Cheung, Man-Ka Marcella MK; Yeo, Giles S H GS
Publication Date: 2011

Variant appearance in text: FTO: R322Q
PubMed Link: 22649359
Variant Present in the following documents:
  • Main text
  • fendo-02-00004.pdf
View BVdb publication page



Prevalence of loss-of-function FTO mutations in lean and obese individuals.

Diabetes
Meyre, David D; Proulx, Karine K; Kawagoe-Takaki, Hiroko H; Vatin, Vincent V; Gutiérrez-Aguilar, Ruth R; Lyon, Debbie D; Ma, Marcella M; Choquet, Helene H; Horber, Fritz F; Van Hul, Wim W; Van Gaal, Luc L; Balkau, Beverley B; Visvikis-Siest, Sophie S; Pattou, François F; Farooqi, I Sadaf IS; Saudek, Vladimir V; O'Rahilly, Stephen S; Froguel, Philippe P; Sedgwick, Barbara B; Yeo, Giles S H GS
Publication Date: 2010-01

Variant appearance in text: FTO: R322Q
PubMed Link: 19833892
Variant Present in the following documents:
  • Main text
  • zdb311.pdf
View BVdb publication page