Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.
Nature Communications
Schmidt, Amand F AF; Hunt, Nicholas B NB; Gordillo-Marañón, Maria M; Charoen, Pimphen P; Drenos, Fotios F; Kivimaki, Mika M; Lawlor, Deborah A DA; Giambartolomei, Claudia C; Papacosta, Olia O; Chaturvedi, Nishi N; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Wannamethee, Goya G; Wong, Andrew A; Price, Jackie F JF; Hughes, Alun D AD; Gaunt, Tom R TR; Franceschini, Nora N; Mook-Kanamori, Dennis O DO; Zwierzyna, Magdalena M; Sofat, Reecha R; Hingorani, Aroon D AD; Finan, Chris C
Candidate Gene Analysis Reveals Strong Association of CETP Variants With High Density Lipoprotein Cholesterol and PCSK9 Variants With Low Density Lipoprotein Cholesterol in Ghanaian Adults: An AWI-Gen Sub-Study.
Frontiers In Genetics
Agongo, Godfred G; Amenga-Etego, Lucas L; Nonterah, Engelbert A EA; Debpuur, Cornelius C; Choudhury, Ananyo A; Bentley, Amy R AR; Oduro, Abraham R AR; Rotimi, Charles N CN; Crowther, Nigel J NJ; Ramsay, Michèle M; , ; H Africa,
Multiplexed Targeted Resequencing Identifies Coding and Regulatory Variation Underlying Phenotypic Extremes of High-Density Lipoprotein Cholesterol in Humans.
Circulation. Genomic And Precision Medicine
Khetarpal, Sumeet A SA; Babb, Paul L PL; Zhao, Wei W; Hancock-Cerutti, William F WF; Brown, Christopher D CD; Rader, Daniel J DJ; Voight, Benjamin F BF
Genetic variations of cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: a systematic review.
Association of CETP Gene Variants With Risk for Vascular and Nonvascular Diseases Among Chinese Adults.
Jama Cardiology
Millwood, Iona Y IY; Bennett, Derrick A DA; Holmes, Michael V MV; Boxall, Ruth R; Guo, Yu Y; Bian, Zheng Z; Yang, Ling L; Sansome, Sam S; Chen, Yiping Y; Du, Huaidong H; Yu, Canqing C; Hacker, Alex A; Reilly, Dermot F DF; Tan, Yunlong Y; Hill, Michael R MR; Chen, Junshi J; Peto, Richard R; Shen, Hongbing H; Collins, Rory R; Clarke, Robert R; Li, Liming L; Walters, Robin G RG; Chen, Zhengming Z; ,
Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities.
Journal Of The Neurological Sciences
Owolabi, Mayowa M; Peprah, Emmanuel E; Xu, Huichun H; Akinyemi, Rufus R; Tiwari, Hemant K HK; Irvin, Marguerite R MR; Wahab, Kolawole Wasiu KW; Arnett, Donna K DK; Ovbiagele, Bruce B
Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C.
Npj Aging And Mechanisms Of Disease
van Leeuwen, Elisabeth M EM; Huffman, Jennifer E JE; Bis, Joshua C JC; Isaacs, Aaron A; Mulder, Monique M; Sabo, Aniko A; Smith, Albert V AV; Demissie, Serkalem S; Manichaikul, Ani A; Brody, Jennifer A JA; Feitosa, Mary F MF; Duan, Qing Q; Schraut, Katharina E KE; Navarro, Pau P; van Vliet-Ostaptchouk, Jana V JV; Zhu, Gu G; Mbarek, Hamdi H; Trompet, Stella S; Verweij, Niek N; Lyytikäinen, Leo-Pekka LP; Deelen, Joris J; Nolte, Ilja M IM; van der Laan, Sander W SW; Davies, Gail G; Vermeij-Verdoold, Andrea Jm AJ; van Oosterhout, Andy Alj AA; Vergeer-Drop, Jeannette M JM; Arking, Dan E DE; Trochet, Holly H; , ; Medina-Gomez, Carolina C; Rivadeneira, Fernando F; Uitterlinden, Andre G AG; Dehghan, Abbas A; Franco, Oscar H OH; Sijbrands, Eric J EJ; Hofman, Albert A; White, Charles C CC; Mychaleckyj, Josyf C JC; Peloso, Gina M GM; Swertz, Morris A MA; , ; Willemsen, Gonneke G; de Geus, Eco J EJ; Milaneschi, Yuri Y; Penninx, Brenda Wjh BW; Ford, Ian I; Buckley, Brendan M BM; de Craen, Anton Jm AJ; Starr, John M JM; Deary, Ian J IJ; Pasterkamp, Gerard G; Oldehinkel, Albertine J AJ; Snieder, Harold H; Slagboom, P Eline PE; Nikus, Kjell K; Kähönen, Mika M; Lehtimäki, Terho T; Viikari, Jorma S JS; Raitakari, Olli T OT; van der Harst, Pim P; Jukema, J Wouter JW; Hottenga, Jouke-Jan JJ; Boomsma, Dorret I DI; Whitfield, John B JB; Montgomery, Grant G; Martin, Nicholas G NG; , ; Polasek, Ozren O; Vitart, Veronique V; Hayward, Caroline C; Kolcic, Ivana I; Wright, Alan F AF; Rudan, Igor I; Joshi, Peter K PK; Wilson, James F JF; Lange, Leslie A LA; Wilson, James G JG; Gudnason, Vilmundur V; Harris, Tamar B TB; Morrison, Alanna C AC; Borecki, Ingrid B IB; Rich, Stephen S SS; Padmanabhan, Sandosh S; Psaty, Bruce M BM; Rotter, Jerome I JI; Smith, Blair H BH; Boerwinkle, Eric E; Cupples, L Adrienne LA; van Duijn, Cornelia C
Genetic variants in CETP increase risk of intracerebral hemorrhage.
Annals Of Neurology
Anderson, Christopher D CD; Falcone, Guido J GJ; Phuah, Chia-Ling CL; Radmanesh, Farid F; Brouwers, H Bart HB; Battey, Thomas W K TW; Biffi, Alessandro A; Peloso, Gina M GM; Liu, Dajiang J DJ; Ayres, Alison M AM; Goldstein, Joshua N JN; Viswanathan, Anand A; Greenberg, Steven M SM; Selim, Magdy M; Meschia, James F JF; Brown, Devin L DL; Worrall, Bradford B BB; Silliman, Scott L SL; Tirschwell, David L DL; Flaherty, Matthew L ML; Kraft, Peter P; Jagiella, Jeremiasz M JM; Schmidt, Helena H; Hansen, Björn M BM; Jimenez-Conde, Jordi J; Giralt-Steinhauer, Eva E; Elosua, Roberto R; Cuadrado-Godia, Elisa E; Soriano, Carolina C; van Nieuwenhuizen, Koen M KM; Klijn, Catharina J M CJ; Rannikmae, Kristiina K; Samarasekera, Neshika N; Al-Shahi Salman, Rustam R; Sudlow, Catherine L CL; Deary, Ian J IJ; Morotti, Andrea A; Pezzini, Alessandro A; Pera, Joanna J; Urbanik, Andrzej A; Pichler, Alexander A; Enzinger, Christian C; Norrving, Bo B; Montaner, Joan J; Fernandez-Cadenas, Israel I; Delgado, Pilar P; Roquer, Jaume J; Lindgren, Arne A; Slowik, Agnieszka A; Schmidt, Reinhold R; Kidwell, Chelsea S CS; Kittner, Steven J SJ; Waddy, Salina P SP; Langefeld, Carl D CD; Abecasis, Goncalo G; Willer, Cristen J CJ; Kathiresan, Sekar S; Woo, Daniel D; Rosand, Jonathan J; ,
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
Bmc Genomics
Ligthart, Symen S; Vaez, Ahmad A; Hsu, Yi-Hsiang YH; , ; , ; , ; Stolk, Ronald R; Uitterlinden, André G AG; Hofman, Albert A; Alizadeh, Behrooz Z BZ; Franco, Oscar H OH; Dehghan, Abbas A
Association between Eight Functional Polymorphisms and Haplotypes in the Cholesterol Ester Transfer Protein (CETP) Gene and Dyslipidemia in National Minority Adults in the Far West Region of China.
International Journal Of Environmental Research And Public Health
Guo, Shuxia S; Hu, Yunhua Y; Ding, Yusong Y; Liu, Jiaming J; Zhang, Mei M; Ma, Rulin R; Guo, Heng H; Wang, Kui K; He, Jia J; Yan, Yizhong Y; Rui, Dongsheng D; Sun, Feng F; Mu, Lati L; Niu, Qiang Q; Zhang, Jingyu J; Li, Shugang S
Resequencing of the CETP gene in American whites and African blacks: Association of rare and common variants with HDL-cholesterol levels.
Metabolism: Clinical And Experimental
Pirim, Dilek D; Wang, Xingbin X; Niemsiri, Vipavee V; Radwan, Zaheda H ZH; Bunker, Clareann H CH; Hokanson, John E JE; Hamman, Richard F RF; Barmada, M Michael MM; Demirci, F Yesim FY; Kamboh, M Ilyas MI
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Analysis of metabolic syndrome components in >15 000 african americans identifies pleiotropic variants: results from the population architecture using genomics and epidemiology study.
Circulation. Cardiovascular Genetics
Carty, Cara L CL; Bhattacharjee, Samsiddhi S; Haessler, Jeff J; Cheng, Iona I; Hindorff, Lucia A LA; Aroda, Vanita V; Carlson, Christopher S CS; Hsu, Chun-Nan CN; Wilkens, Lynne L; Liu, Simin S; Selvin, Elizabeth E; Jackson, Rebecca R; North, Kari E KE; Peters, Ulrike U; Pankow, James S JS; Chatterjee, Nilanjan N; Kooperberg, Charles C
Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation.
Plos One
Wood, Andrew R AR; Perry, John R B JR; Tanaka, Toshiko T; Hernandez, Dena G DG; Zheng, Hou-Feng HF; Melzer, David D; Gibbs, J Raphael JR; Nalls, Michael A MA; Weedon, Michael N MN; Spector, Tim D TD; Richards, J Brent JB; Bandinelli, Stefania S; Ferrucci, Luigi L; Singleton, Andrew B AB; Frayling, Timothy M TM
Determination of genetic predisposition to patent ductus arteriosus in preterm infants.
Pediatrics
Dagle, John M JM; Lepp, Nathan T NT; Cooper, Margaret E ME; Schaa, Kendra L KL; Kelsey, Keegan J P KJ; Orr, Kristin L KL; Caprau, Diana D; Zimmerman, Cara R CR; Steffen, Katherine M KM; Johnson, Karen J KJ; Marazita, Mary L ML; Murray, Jeffrey C JC
Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction.
Nutrition & Metabolism
Ruaño, Gualberto G; Windemuth, Andreas A; Kocherla, Mohan M; Holford, Theodore T; Fernandez, Maria Luz ML; Forsythe, Cassandra E CE; Wood, Richard J RJ; Kraemer, William J WJ; Volek, Jeff S JS
Application of pooled genotyping to scan candidate regions for association with HDL cholesterol levels.
Human Genomics
Hinds, David A DA; Seymour, Albert B AB; Durham, L Kathryn LK; Banerjee, Poulabi P; Ballinger, Dennis G DG; Milos, Patrice M PM; Cox, David R DR; Thompson, John F JF; Frazer, Kelly A KA