Cardiometabolic genomics and pharmacogenomics investigations in Filipino Americans: Steps towards precision health and reducing health disparities.
American Heart Journal Plus : Cardiology Research And Practice
Roman, Youssef M YM; McClish, Donna D; Price, Elvin T ET; Sabo, Roy T RT; Woodward, Owen M OM; Mersha, Tesfaye B TB; Shah, Nehal N; Armada, Andrew A; Terkeltaub, Robert R
"GENYAL" Study to Childhood Obesity Prevention: Methodology and Preliminary Results.
Frontiers In Nutrition
Marcos-Pasero, Helena H; Aguilar-Aguilar, Elena E; de la Iglesia, Rocío R; Espinosa-Salinas, Isabel I; Molina, Susana S; Colmenarejo, Gonzalo G; Martínez, J Alfredo JA; Ramírez de Molina, Ana A; Reglero, Guillermo G; Loria-Kohen, Viviana V
Identification and replication of novel genetic variants of ABO gene to reduce the incidence of diseases and promote longevity by modulating lipid homeostasis.
Aging
Ni, Xiaolin X; Bai, Chen C; Nie, Chao C; Qi, Liping L; Liu, Yifang Y; Yuan, Huiping H; Zhu, Xiaoquan X; Sun, Liang L; Zhou, Qi Q; Li, Yan Y; Zhen, Hefu H; Su, Huabing H; Li, Rongqiao R; Lan, Rushu R; Pang, Guofang G; Lv, Yuan Y; Zhang, Wei W; Yang, Fan F; Yao, Yao Y; Chen, Chen C; Wang, Zhaoping Z; Gao, Danni D; Zhang, Nan N; Zhang, Shenqi S; Zhang, Li L; Wu, Zhu Z; Hu, Caiyou C; Zeng, Yi Y; Yang, Ze Z
Identification and replication of novel genetic variants of ABO gene to reduce the incidence of diseases and promote longevity by modulating lipid homeostasis.
Aging
Ni, Xiaolin X; Bai, Chen C; Nie, Chao C; Qi, Liping L; Liu, Yifang Y; Yuan, Huiping H; Zhu, Xiaoquan X; Sun, Liang L; Zhou, Qi Q; Li, Yan Y; Zhen, Hefu H; Su, Huabing H; Li, Rongqiao R; Lan, Rushu R; Pang, Guofang G; Lv, Yuan Y; Zhang, Wei W; Yang, Fan F; Yao, Yao Y; Chen, Chen C; Wang, Zhaoping Z; Gao, Danni D; Zhang, Nan N; Zhang, Shenqi S; Zhang, Li L; Wu, Zhu Z; Hu, Caiyou C; Zeng, Yi Y; Yang, Ze Z
Engineered pegRNAs improve prime editing efficiency.
Nature Biotechnology
Nelson, James W JW; Randolph, Peyton B PB; Shen, Simon P SP; Everette, Kelcee A KA; Chen, Peter J PJ; Anzalone, Andrew V AV; An, Meirui M; Newby, Gregory A GA; Chen, Jonathan C JC; Hsu, Alvin A; Liu, David R DR
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease.
Nature Communications
Schmidt, Amand F AF; Hunt, Nicholas B NB; Gordillo-Marañón, Maria M; Charoen, Pimphen P; Drenos, Fotios F; Kivimaki, Mika M; Lawlor, Deborah A DA; Giambartolomei, Claudia C; Papacosta, Olia O; Chaturvedi, Nishi N; Bis, Joshua C JC; O'Donnell, Christopher J CJ; Wannamethee, Goya G; Wong, Andrew A; Price, Jackie F JF; Hughes, Alun D AD; Gaunt, Tom R TR; Franceschini, Nora N; Mook-Kanamori, Dennis O DO; Zwierzyna, Magdalena M; Sofat, Reecha R; Hingorani, Aroon D AD; Finan, Chris C
Alcohol Drinking, Apolipoprotein Polymorphisms and the Risk of Cardiovascular Diseases.
Current Neurovascular Research
Ceci, Flavio M FM; Ceccanti, Mauro M; Petrella, Carla C; Vitali, Mario M; Messina, Marisa P MP; Chaldakov, George N GN; Greco, Antonio A; Ralli, Massimo M; Lucarelli, Marco M; Angeloni, Antonio A; Fiore, Marco M; Ferraguti, Giampiero G
Alcohol Drinking, Apolipoprotein Polymorphisms and the Risk of Cardiovascular Diseases.
Current Neurovascular Research
Ceci, Flavio M FM; Ceccanti, Mauro M; Petrella, Carla C; Vitali, Mario M; Messina, Marisa P MP; Chaldakov, George N GN; Greco, Antonio A; Ralli, Massimo M; Lucarelli, Marco M; Angeloni, Antonio A; Fiore, Marco M; Ferraguti, Giampiero G
Polygenic Risk Score of Longevity Predicts Longer Survival Across an Age Continuum.
The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
Tesi, Niccolo' N; van der Lee, Sven J SJ; Hulsman, Marc M; Jansen, Iris E IE; Stringa, Najada N; van Schoor, Natasja M NM; Scheltens, Philip P; van der Flier, Wiesje M WM; Huisman, Martijn M; Reinders, Marcel J T MJT; Holstege, Henne H
Multi-level evidence of an allelic hierarchy of USH2A variants in hearing, auditory processing and speech/language outcomes.
Communications Biology
Perrino, Peter A PA; Talbot, Lidiya L; Kirkland, Rose R; Hill, Amanda A; Rendall, Amanda R AR; Mountford, Hayley S HS; Taylor, Jenny J; , ; Buscarello, Alexzandrea N AN; Lahiri, Nayana N; Saggar, Anand A; Fitch, R Holly RH; Newbury, Dianne F DF
The Effect of Haplotypes in the CETP and LIPC Genes on the Triglycerides to HDL-C Ratio and Its Components in the Roma and Hungarian General Populations.
Genes
Piko, Peter P; Fiatal, Szilvia S; Werissa, Nardos Abebe NA; Bekele, Bayu Begashaw BB; Racz, Gabor G; Kosa, Zsigmond Z; Sandor, Janos J; Adany, Roza R
Introducing the first whole genomes of nationals from the United Arab Emirates.
Scientific Reports
AlSafar, Habiba S HS; Al-Ali, Mariam M; Elbait, Gihan Daw GD; Al-Maini, Mustafa H MH; Ruta, Dymitr D; Peramo, Braulio B; Henschel, Andreas A; Tay, Guan K GK
Phenotypic severity in a family with MEND syndrome is directly associated with the accumulation of potentially functional variants of cholesterol homeostasis genes.
Molecular Genetics & Genomic Medicine
Barboza-Cerda, María Carmen MC; Barboza-Quintana, Oralia O; Martínez-Aldape, Gerardo G; Garza-Guajardo, Raquel R; Déctor, Miguel Angel MA
CETP, LIPC, and SCARB1 variants in individuals with extremely high high-density lipoprotein-cholesterol levels.
Scientific Reports
Lee, Chan Joo CJ; Park, Mun Su MS; Kim, Miso M; Ann, Soo-Jin SJ; Lee, Jaeho J; Park, Sungha S; Kang, Seok-Min SM; Jang, Yangsoo Y; Lee, Ji Hyun JH; Lee, Sang-Hak SH
The Association of Polymorphisms in Circadian Clock and Lipid Metabolism Genes With 2nd Trimester Lipid Levels and Preterm Birth.
Frontiers In Genetics
Kovac, Ursa U; Jasper, Elizabeth A EA; Smith, Caitlin J CJ; Baer, Rebecca J RJ; Bedell, Bruce B; Donovan, Brittney M BM; Weathers, Nancy N; Prosenc Zmrzljak, Ursula U; Jelliffe-Pawlowski, Laura L LL; Rozman, Damjana D; Ryckman, Kelli K KK
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
PopCluster: an algorithm to identify genetic variants with ethnicity-dependent effects.
Bioinformatics (Oxford, England)
Gurinovich, Anastasia A; Bae, Harold H; Farrell, John J JJ; Andersen, Stacy L SL; Monti, Stefano S; Puca, Annibale A; Atzmon, Gil G; Barzilai, Nir N; Perls, Thomas T TT; Sebastiani, Paola P
Genetic and secondary causes of severe HDL deficiency and cardiovascular disease.
Journal Of Lipid Research
Geller, Andrew S AS; Polisecki, Eliana Y EY; Diffenderfer, Margaret R MR; Asztalos, Bela F BF; Karathanasis, Sotirios K SK; Hegele, Robert A RA; Schaefer, Ernst J EJ
Multiplexed Targeted Resequencing Identifies Coding and Regulatory Variation Underlying Phenotypic Extremes of High-Density Lipoprotein Cholesterol in Humans.
Circulation. Genomic And Precision Medicine
Khetarpal, Sumeet A SA; Babb, Paul L PL; Zhao, Wei W; Hancock-Cerutti, William F WF; Brown, Christopher D CD; Rader, Daniel J DJ; Voight, Benjamin F BF
Association of Genes in the High-Density Lipoprotein Metabolic Pathway with Polypoidal Choroidal Vasculopathy in Asian Population: A Systematic Review and Meta-Analysis.
Mechanisms and modulators of cognitive training gain transfer in cognitively healthy aging: study protocol of the AgeGain study.
Trials
Wolf, Dominik D; Tüscher, Oliver O; Teipel, Stefan S; Mierau, Andreas A; Strüder, Heiko H; Drzezga, Alexander A; Baier, Bernhard B; Binder, Harald H; Fellgiebel, Andreas A; ,
Cholesteryl ester transfer protein gene variations and macronutrient intakes interaction in relation to metabolic syndrome: Tehran lipid and glucose study.
Genetic variations of cholesteryl ester transfer protein and diet interactions in relation to lipid profiles and coronary heart disease: a systematic review.
Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes.
Lipids
Klingel, Shannon L SL; Roke, Kaitlin K; Hidalgo, Bertha B; Aslibekyan, Stella S; Straka, Robert J RJ; An, Ping P; Province, Michael A MA; Hopkins, Paul N PN; Arnett, Donna K DK; Ordovas, Jose M JM; Lai, Chao-Qiang CQ; Mutch, David M DM