Publications:

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Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2.

Nature Communications

Sanders, Brian C BC; Pokhrel, Suman S; Labbe, Audrey D AD; Mathews, Irimpan I II; Cooper, Connor J CJ; Davidson, Russell B RB; Phillips, Gwyndalyn G; Weiss, Kevin L KL; Zhang, Qiu Q; O'Neill, Hugh H; Kaur, Manat M; Schmidt, Jurgen G JG; Reichard, Walter W; Surendranathan, Surekha S; Parvathareddy, Jyothi J; Phillips, Lexi L; Rainville, Christopher C; Sterner, David E DE; Kumaran, Desigan D; Andi, Babak B; Babnigg, Gyorgy G; Moriarty, Nigel W NW; Adams, Paul D PD; Joachimiak, Andrzej A; Hurst, Brett L BL; Kumar, Suresh S; Butt, Tauseef R TR; Jonsson, Colleen B CB; Ferrins, Lori L; Wakatsuki, Soichi S; Galanie, Stephanie S; Head, Martha S MS; Parks, Jerry M JM

Publication Date: 2023-03-28

Variant appearance in text: HP: C111S

PubMed Link: 36977673

Variant Present in the following documents:

• Main text
• 41467_2023_Article_37254.pdf

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Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2.

Research Square

Sanders, Brian B; Pokhrel, Suman S; Labbe, Audrey A; Mathews, Irimpan I; Cooper, Connor C; Davidson, Russell R; Phillips, Gwyndalyn G; Weiss, Kevin K; Zhang, Qiu Q; O'Neill, Hugh H; Kaur, Manat M; Ferrins, Lori L; Schmidt, Jurgen J; Reichard, Walter W; Surendranathan, Surekha S; Parvathareddy, Jyothi J; Phillips, Lexi L; Rainville, Christopher C; Sterner, David D; Kumaran, Desigan D; Andi, Babak B; Babnigg, Gyorgy G; Moriarty, Nigel N; Adams, Paul P; Joachimiak, Andrzej A; Hurst, Brett B; Kumar, Suresh S; Butt, Tauseef T; Jonsson, Colleen C; Wakatsuki, Soichi S; Galanie, Stephanie S; Head, Martha M; Parks, Jerry J

Publication Date: 2022-07-21

Variant appearance in text: HP: C111S

PubMed Link: 35898342

Variant Present in the following documents:

• nihpp-rs1840200v1.pdf

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SOD1 gains pro-oxidant activity upon aberrant oligomerization: change in enzymatic activity by intramolecular disulfide bond cleavage.

Scientific Reports

Yamazaki, Kosuke K; Tahara, Shinya S; Ohyama, Takumi T; Kuroi, Kunisato K; Nakabayashi, Takakazu T

Publication Date: 2022-07-11

Variant appearance in text: HP: C111S

PubMed Link: 35817830

Variant Present in the following documents:

• Main text
• 41598_2022_Article_15701.pdf

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Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors.

Frontiers In Chemistry

Calleja, Dale J DJ; Kuchel, Nathan N; Lu, Bernadine G C BGC; Birkinshaw, Richard W RW; Klemm, Theresa T; Doerflinger, Marcel M; Cooney, James P JP; Mackiewicz, Liana L; Au, Amanda E AE; Yap, Yu Q YQ; Blackmore, Timothy R TR; Katneni, Kasiram K; Crighton, Elly E; Newman, Janet J; Jarman, Kate E KE; Call, Melissa J MJ; Lechtenberg, Bernhard C BC; Czabotar, Peter E PE; Pellegrini, Marc M; Charman, Susan A SA; Lowes, Kym N KN; Mitchell, Jeffrey P JP; Nachbur, Ueli U; Lessene, Guillaume G; Komander, David D

Publication Date: 2022

Variant appearance in text: HP: C111S

PubMed Link: 35494659

Variant Present in the following documents:

• Main text
• fchem-10-861209.pdf

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Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.

Nature Communications

Paluda, Andrej A; Middleton, Adam J AJ; Rossig, Claudia C; Mace, Peter D PD; Day, Catherine L CL

Publication Date: 2022-03-04

Variant appearance in text: HP: C111S

PubMed Link: 35246518

Variant Present in the following documents:

• Main text
• 41467_2022_Article_28782.pdf

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Potent and Selective Covalent Inhibitors of the Papain-like Protease from SARS-CoV-2.

Research Square

Sanders, Brian B; Pohkrel, Suman S; Labbe, Audrey A; Mathews, Irimpan I; Cooper, Connor C; Davidson, Russell R; Phillips, Gwyndalyn G; Weiss, Kevin K; Zhang, Qiu Q; O'Neill, Hugh H; Kaur, Manat M; Ferrins, Lori L; Schmidt, Jurgen J; Reichard, Walter W; Surendranathan, Surekha S; Kumaran, Desigan D; Andi, Babak B; Babnigg, Gyorgy G; Moriarty, Nigel N; Adams, Paul P; Joachimiak, Andrzej A; Jonsson, Colleen C; Wakatsuki, Soichi S; Galanie, Stephanie S; Head, Martha M; Parks, Jerry J

Publication Date: 2021-10-08

Variant appearance in text: HP: C111S

PubMed Link: 34642689

Variant Present in the following documents:

• Main text
• nihpp-rs906621v1.pdf

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Conformational Dynamics in the Interaction of SARS-CoV-2 Papain-like Protease with Human Interferon-Stimulated Gene 15 Protein.

The Journal Of Physical Chemistry Letters

Leite, Wellington C WC; Weiss, Kevin L KL; Phillips, Gwyndalyn G; Zhang, Qiu Q; Qian, Shuo S; Tsutakawa, Susan E SE; Coates, Leighton L; O'Neill, Hugh H

Publication Date: 2021-06-17

Variant appearance in text: HP: C111S

PubMed Link: 34110168

Variant Present in the following documents:

• jz1c00831_si_001.pdf

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Neddylation requires glycyl-tRNA synthetase to protect activated E2.

Nature Structural & Molecular Biology

Mo, Zhongying Z; Zhang, Qian Q; Liu, Ze Z; Lauer, Janelle J; Shi, Yi Y; Sun, Litao L; Griffin, Patrick R PR; Yang, Xiang-Lei XL

Publication Date: 2016-08

Variant appearance in text: HP: C111S

PubMed Link: 27348078

Variant Present in the following documents:

• nihms-792023.pdf

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Conformational Disorder of the Most Immature Cu, Zn-Superoxide Dismutase Leading to Amyotrophic Lateral Sclerosis.

The Journal Of Biological Chemistry

Furukawa, Yoshiaki Y; Anzai, Itsuki I; Akiyama, Shuji S; Imai, Mizue M; Cruz, Fatima Joy C FJ; Saio, Tomohide T; Nagasawa, Kenichi K; Nomura, Takao T; Ishimori, Koichiro K

Publication Date: 2016-02-19

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PubMed Link: 26694608

Variant Present in the following documents:

• Main text

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