HP c.503A>C ;(p.D168A)

Variant ID: 16-72094071-A-C

NM_005143.3(HP):c.503A>C;(p.D168A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Identification of repurposing therapeutics toward SARS-CoV-2 main protease by virtual screening.

Plos One
Sanachai, Kamonpan K; Somboon, Tuanjai T; Wilasluck, Patcharin P; Deetanya, Peerapon P; Wolschann, Peter P; Langer, Thierry T; Lee, Vannajan Sanghiran VS; Wangkanont, Kittikhun K; Rungrotmongkol, Thanyada T; Hannongbua, Supot S
Publication Date: 2022

Variant appearance in text: HP: D168A
PubMed Link: 35771802
Variant Present in the following documents:
  • pone.0269563.pdf
View BVdb publication page



Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors.

The Journal Of Biological Chemistry
Dultz, Georg G; Shimakami, Tetsuro T; Schneider, Markus M; Murai, Kazuhisa K; Yamane, Daisuke D; Marion, Antoine A; Zeitler, Tobias M TM; Stross, Claudia C; Grimm, Christian C; Richter, Rebecca M RM; Bäumer, Katrin K; Yi, MinKyung M; Biondi, Ricardo M RM; Zeuzem, Stefan S; Tampé, Robert R; Antes, Iris I; Lange, Christian M CM; Welsch, Christoph C
Publication Date: 2020-10-02

Variant appearance in text: HP: D168A
PubMed Link: 32747444
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance.

Acs Chemical Biology
Ali, Akbar A; Aydin, Cihan C; Gildemeister, Reinhold R; Romano, Keith P KP; Cao, Hong H; Ozen, Ayşegül A; Soumana, Djade D; Newton, Alicia A; Petropoulos, Christos J CJ; Huang, Wei W; Schiffer, Celia A CA
Publication Date: 2013-07-19

Variant appearance in text: HP: D168A
PubMed Link: 23594083
Variant Present in the following documents:
  • Main text
View BVdb publication page