Extended interaction networks with HCV protease NS3-4A substrates explain the lack of adaptive capability against protease inhibitors.
The Journal Of Biological Chemistry
Dultz, Georg G; Shimakami, Tetsuro T; Schneider, Markus M; Murai, Kazuhisa K; Yamane, Daisuke D; Marion, Antoine A; Zeitler, Tobias M TM; Stross, Claudia C; Grimm, Christian C; Richter, Rebecca M RM; Bäumer, Katrin K; Yi, MinKyung M; Biondi, Ricardo M RM; Zeuzem, Stefan S; Tampé, Robert R; Antes, Iris I; Lange, Christian M CM; Welsch, Christoph C