GRIN2A c.1909_1910delinsGC ;(p.F637A)

Variant ID: 16-9923377-AA-GC

NM_001134407.1(GRIN2A):c.1909_1910delinsGC;(p.F637A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation.

Frontiers In Pharmacology
Langer, Kai K; Müller-Längle, Adriana A; Wempe, Jannik J; Laube, Bodo B
Publication Date: 2021

Variant appearance in text: GluN2A: F637A
PubMed Link: 34658899
Variant Present in the following documents:
  • Main text
View BVdb publication page



Three-dimensional missense tolerance ratio analysis.

Genome Research
Perszyk, Riley E RE; Kristensen, Anders S AS; Lyuboslavsky, Polina P; Traynelis, Stephen F SF
Publication Date: 2021-08

Variant appearance in text: GRIN2A: F637A
PubMed Link: 34301626
Variant Present in the following documents:
  • supp_gr.275528.121_Supplemental_Dataset_2.xlsx, sheet 1
View BVdb publication page



Two adjacent phenylalanines in the NMDA receptor GluN2A subunit M3 domain interactively regulate alcohol sensitivity and ion channel gating.

Neuropharmacology
Ren, Hong H; Zhao, Yulin Y; Wu, Man M; Dwyer, Donard S DS; Peoples, Robert W RW
Publication Date: 2017-03-01

Variant appearance in text: GluN2A: F637A
PubMed Link: 27876530
Variant Present in the following documents:
  • Main text
View BVdb publication page