Publications:

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Identification of Transporter Polymorphisms Influencing Metformin Pharmacokinetics in Healthy Volunteers.

Journal Of Personalized Medicine

Saiz-Rodríguez, Miriam M; Ochoa, Dolores D; Zubiaur, Pablo P; Navares-Gómez, Marcos M; Román, Manuel M; Camargo-Mamani, Paola P; Luquero-Bueno, Sergio S; Villapalos-García, Gonzalo G; Alcaraz, Raquel R; Mejía-Abril, Gina G; Santos-Mazo, Estefanía E; Abad-Santos, Francisco F

Publication Date: 2023-03-08

Variant appearance in text: rs2289669

PubMed Link: 36983671

Variant Present in the following documents:

• Main text
• jpm-13-00489.pdf

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The association study between changes in HbA1C with rs2250486 and rs67238751 genetic variants for SLC47A1 in newly diagnosed Iranian patients with type 2 diabetes mellitus: 6 months follow-up study.

Endocrinology, Diabetes & Metabolism

Semnani, Armina A; Kazerouni, Faranak F; Kalbasi, Saeid S; Shahrokhi, Seyedeh Zahra SZ; Rahimipour, Ali A

Publication Date: 2023-02-14

Variant appearance in text: rs2289669

PubMed Link: 36786075

Variant Present in the following documents:

• Main text
• EDM2-6-e410.pdf

View BVdb publication page

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Polymorphic renal transporters and cisplatin's toxicity in urinary bladder cancer patients: current perspectives and future directions.

Medical Oncology (Northwood, London, England)

Selim, Mohamed S MS; Kassem, Amira B AB; El-Bassiouny, Noha A NA; Salahuddin, Ahmad A; Abu El-Ela, Raghda Y RY; Hamza, Marwa Samir MS

Publication Date: 2023-01-17

Variant appearance in text: rs2289669

PubMed Link: 36650399

Variant Present in the following documents:

• Main text
• 12032_2022_Article_1928.pdf

View BVdb publication page

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A Review of the Impact of Pharmacogenetics and Metabolomics on the Efficacy of Metformin in Type 2 Diabetes.

International Journal Of Medical Sciences

Damanhouri, Zoheir A ZA; Alkreathy, Huda M HM; Alharbi, Fawaz A FA; Abualhamail, Haneen H; Ahmad, Muhammad S MS

Publication Date: 2023

Variant appearance in text: rs2289669

PubMed Link: 36619226

Variant Present in the following documents:

• ijmsv20p0142.pdf

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Impact of solute carrier transporter gene polymorphisms on serum creatinine concentrations in healthy volunteers.

Pharmacology Research & Perspectives

Yokoyama, Satoshi S; Nakagawa, Junichi J; Kudo, Masakiyo M; Aiuchi, Naoya N; Seito, Tatsuya T; Isida, Mizuri M; Mikami, Tatsuya T; Ihara, Kazushige K; Nakaji, Shigeyuki S; Niioka, Takenori T

Publication Date: 2023-02

Variant appearance in text: rs2289669

PubMed Link: 36594679

Variant Present in the following documents:

• Main text
• PRP2-11-e1048.pdf

View BVdb publication page

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Advances in multi-omics study of biomarkers of glycolipid metabolism disorder.

Computational And Structural Biotechnology Journal

Fang, Xinyi X; Miao, Runyu R; Wei, Jiahua J; Wu, Haoran H; Tian, Jiaxing J

Publication Date: 2022

Variant appearance in text: rs2289669

PubMed Link: 36382190

Variant Present in the following documents:

• main.pdf

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Pharmacogenomics in Psychiatry Practice: The Value and the Challenges.

International Journal Of Molecular Sciences

Alchakee, Aminah A; Ahmed, Munazza M; Eldohaji, Leen L; Alhaj, Hamid H; Saber-Ayad, Maha M

Publication Date: 2022-11-03

Variant appearance in text: rs2289669

PubMed Link: 36362270

Variant Present in the following documents:

• Main text
• ijms-23-13485.pdf

View BVdb publication page

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Association of SLC22A1, SLC22A2, SLC47A1, and SLC47A2 Polymorphisms with Metformin Efficacy in Type 2 Diabetic Patients.

Biomedicines

Chen, Peixian P; Cao, Yumin Y; Chen, Shenren S; Liu, Zhike Z; Chen, Shiyi S; Guo, Yali Y

Publication Date: 2022-10-12

Variant appearance in text: rs2289669

PubMed Link: 36289808

Variant Present in the following documents:

• Main text
• biomedicines-10-02546.pdf

View BVdb publication page

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The Association Between Genetic Polymorphisms of Transporter Genes and Prognosis of Platinum-Based Chemotherapy in Lung Cancer Patients.

Pharmacogenomics And Personalized Medicine

He, Jia J; Wang, Zhan Z; Zou, Ting T; Wang, Ying Y; Li, Xiang-Ping XP; Chen, Juan J

Publication Date: 2022

Variant appearance in text: rs2289669

PubMed Link: 36131844

Variant Present in the following documents:

• Main text
• pgpm-15-817.pdf

View BVdb publication page

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A genomic deletion encompassing CRYBB2-CRYBB2P1 is responsible for autosomal recessive congenital cataracts.

Human Genome Variation

Irum, Bushra B; Kabir, Firoz F; Shoshany, Nadav N; Khan, Shahid Y SY; Rauf, Bushra B; Naeem, Muhammad Asif MA; Qaiser, Tanveer A TA; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-09-08

Variant appearance in text: rs2289669

PubMed Link: 36075891

Variant Present in the following documents:

• 41439_2022_208_MOESM3_ESM.xlsx, sheet 2
• 41439_2022_208_MOESM5_ESM.xlsx, sheet 2
• 41439_2022_208_MOESM4_ESM.xlsx, sheet 2

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Pharmacogenetics of Metformin Transporters Suggests No Association with Therapeutic Inefficacy among Diabetes Type 2 Mexican Patients.

Pharmaceuticals (Basel, Switzerland)

Ortega-Ayala, Adiel A; Rodríguez-Rivera, Nidia Samara NS; Andrés, Fernando de F; LLerena, Adrián A; Pérez-Silva, Eliseo E; Espinosa-Sánchez, Adriana Guadalupe AG; Molina-Guarneros, Juan Arcadio JA

Publication Date: 2022-06-22

Variant appearance in text: rs2289669

PubMed Link: 35890074

Variant Present in the following documents:

• Main text
• pharmaceuticals-15-00774.pdf

View BVdb publication page

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Determinants in Tailoring Antidiabetic Therapies: A Personalized Approach.

Global Medical Genetics

Rizvi, Aliya A AA; Abbas, Mohammad M; Verma, Sushma S; Verma, Shrikant S; Khan, Almas A; Raza, Syed T ST; Mahdi, Farzana F

Publication Date: 2022-06

Variant appearance in text: rs2289669

PubMed Link: 35707783

Variant Present in the following documents:

• Main text

View BVdb publication page

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Precision Nephrology in Patients with Diabetes and Chronic Kidney Disease.

International Journal Of Molecular Sciences

Provenzano, Michele M; Maritati, Federica F; Abenavoli, Chiara C; Bini, Claudia C; Corradetti, Valeria V; La Manna, Gaetano G; Comai, Giorgia G

Publication Date: 2022-05-20

Variant appearance in text: rs2289669

PubMed Link: 35628528

Variant Present in the following documents:

• Main text
• ijms-23-05719.pdf

View BVdb publication page

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A population study of clinically actionable genetic variation affecting drug response from the Middle East.

Npj Genomic Medicine

Jithesh, Puthen Veettil PV; Abuhaliqa, Mohammed M; Syed, Najeeb N; Ahmed, Ikhlak I; El Anbari, Mohammed M; Bastaki, Kholoud K; Sherif, Shimaa S; Umlai, Umm-Kulthum UK; Jan, Zainab Z; Gandhi, Geethanjali G; Manickam, Chidambaram C; Selvaraj, Senthil S; George, Chinnu C; Bangarusamy, Dhinoth D; Abdel-Latif, Rania R; Al-Shafai, Mashael M; Tatari-Calderone, Zohreh Z; Estivill, Xavier X; Pirmohamed, Munir M; ,

Publication Date: 2022-02-15

Variant appearance in text: rs2289669

PubMed Link: 35169154

Variant Present in the following documents:

• Main text
• 41525_2022_Article_281.pdf

View BVdb publication page

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Analysis of OCT1, OCT2 and OCT3 gene polymorphisms among Type 2 diabetes mellitus subjects in Indian ethnicity, Malaysia.

Saudi Journal Of Biological Sciences

Ghasan Abood Al-Ashoor, Sabah S; Ramachandran, Vasudevan V; Inche Mat, Liyana Najwa LN; Mohamad, Nur Afiqah NA; Mohamed, Mohd Hazmi MH; Wan Sulaiman, Wan Aliaa WA

Publication Date: 2022-01

Variant appearance in text: rs2289669

PubMed Link: 35002441

Variant Present in the following documents:

• main.pdf

View BVdb publication page

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Pharmacogenomics and Personalized Medicine in Type 2 Diabetes Mellitus: Potential Implications for Clinical Practice.

Pharmacogenomics And Personalized Medicine

Venkatachalapathy, Poongothai P; Padhilahouse, Sruthi S; Sellappan, Mohan M; Subramanian, Tharunika T; Kurian, Shilia Jacob SJ; Miraj, Sonal Sekhar SS; Rao, Mahadev M; Raut, Ashwin Ashok AA; Kanwar, Rupinder Kaur RK; Singh, Jitendra J; Khadanga, Sagar S; Mondithoka, Sukumar S; Munisamy, Murali M

Publication Date: 2021

Variant appearance in text: rs2289669

PubMed Link: 34803393

Variant Present in the following documents:

• Main text
• pgpm-14-1441.pdf

View BVdb publication page

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Genomic editing of metformin efficacy-associated genetic variants in SLC47A1 does not alter SLC47A1 expression.

Human Molecular Genetics

Kalamajski, Sebastian S; Huang, Mi M; Dalla-Riva, Jonathan J; Keller, Maria M; Dawed, Adem Y AY; Hansson, Ola O; Pearson, Ewan R ER; , ; Mulder, Hindrik H; Franks, Paul W PW

Publication Date: 2022-02-21

Variant appearance in text: rs2289669

PubMed Link: 34505146

Variant Present in the following documents:

• Main text
• ddab266.pdf

View BVdb publication page

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The Genetics of Adverse Drug Outcomes in Type 2 Diabetes: A Systematic Review.

Frontiers In Genetics

Baye, Assefa M AM; Fanta, Teferi G TG; Siddiqui, Moneeza K MK; Dawed, Adem Y AY

Publication Date: 2021

Variant appearance in text: rs2289669

PubMed Link: 34194474

Variant Present in the following documents:

• Main text
• fgene-12-675053.pdf

View BVdb publication page

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Single Nucleotide Polymorphisms Associated with Metformin and Sulphonylureas' Glycaemic Response among South African Adults with Type 2 Diabetes Mellitus.

Journal Of Personalized Medicine

Masilela, Charity C; Pearce, Brendon B; Ongole, Joven Jebio JJ; Adeniyi, Oladele Vincent OV; Benjeddou, Mongi M

Publication Date: 2021-02-06

Variant appearance in text: rs2289669

PubMed Link: 33561991

Variant Present in the following documents:

• Main text
• jpm-11-00104.pdf

View BVdb publication page

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Oncology and Pharmacogenomics Insights in Polycystic Ovary Syndrome: An Integrative Analysis.

Frontiers In Endocrinology

Yumiceba, Verónica V; López-Cortés, Andrés A; Pérez-Villa, Andy A; Yumiseba, Iván I; Guerrero, Santiago S; García-Cárdenas, Jennyfer M JM; Armendáriz-Castillo, Isaac I; Guevara-Ramírez, Patricia P; Leone, Paola E PE; Zambrano, Ana Karina AK; Paz-Y-Miño, César C

Publication Date: 2020

Variant appearance in text: rs2289669

PubMed Link: 33329391

Variant Present in the following documents:

• Main text
• fendo-11-585130.pdf

View BVdb publication page

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Population pharmacokinetics and dosing optimization of metformin in Chinese patients with type 2 diabetes mellitus.

Medicine

Li, Ling L; Guan, Ziwan Z; Li, Rui R; Zhao, Wei W; Hao, Guoxiang G; Yan, Yan Y; Xu, Yuedong Y; Liao, Lin L; Wang, Huanjun H; Gao, Li L; Wu, Kunrong K; Gao, Yuxia Y; Li, Yan Y

Publication Date: 2020-11-13

Variant appearance in text: rs2289669

PubMed Link: 33181704

Variant Present in the following documents:

• Main text

View BVdb publication page

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Repurposing Drugs for COVID-19: Pharmacokinetics and Pharmacogenomics of Chloroquine and Hydroxychloroquine.

Pharmacogenomics And Personalized Medicine

Babayeva, Mariana M; Loewy, Zvi Z

Publication Date: 2020

Variant appearance in text: rs2289669

PubMed Link: 33122936

Variant Present in the following documents:

• Main text
• pgpm-13-531.pdf

View BVdb publication page

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Genetic Polymorphisms and the Efficacy of Platinum-Based Chemotherapy: Review.

Pharmacogenomics And Personalized Medicine

Afifah, Nadiya Nurul NN; Diantini, Ajeng A; Intania, Ruri R; Abdulah, Rizky R; Barliana, Melisa I MI

Publication Date: 2020

Variant appearance in text: rs2289669

PubMed Link: 33116759

Variant Present in the following documents:

• Main text

View BVdb publication page

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To the Editor.

Ethnicity & Disease

Raj, Gerard Marshall GM; Mathaiyan, Jayanthi J

Publication Date: 2020

Variant appearance in text: rs2289669

PubMed Link: 32989371

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenetics of Type 2 Diabetes-Progress and Prospects.

International Journal Of Molecular Sciences

Nasykhova, Yulia A YA; Tonyan, Ziravard N ZN; Mikhailova, Anastasiia A AA; Danilova, Maria M MM; Glotov, Andrey S AS

Publication Date: 2020-09-18

Variant appearance in text: rs2289669

PubMed Link: 32961860

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenomic Studies of Current Antidiabetic Agents and Potential New Drug Targets for Precision Medicine of Diabetes.

Diabetes Therapy : Research, Treatment And Education Of Diabetes And Related Disorders

Zeng, Zhiwei Z; Huang, Shi-Ying SY; Sun, Tao T

Publication Date: 2020-11

Variant appearance in text: rs2289669

PubMed Link: 32930968

Variant Present in the following documents:

• Main text
• 13300_2020_Article_922.pdf

View BVdb publication page

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Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein-Mediated Drug-Drug Interactions in Healthy Volunteers.

Clinical Pharmacology And Therapeutics

Miyake, Takeshi T; Kimoto, Emi E; Luo, Lina L; Mathialagan, Sumathy S; Horlbogen, Lauren M LM; Ramanathan, Ragu R; Wood, Linda S LS; Johnson, Jillian G JG; Le, Vu H VH; Vourvahis, Manoli M; Rodrigues, A David AD; Muto, Chieko C; Furihata, Kenichi K; Sugiyama, Yuichi Y; Kusuhara, Hiroyuki H

Publication Date: 2021-02

Variant appearance in text: rs2289669

PubMed Link: 32866300

Variant Present in the following documents:

• Main text

View BVdb publication page

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Role of SLC transporters in toxicity induced by anticancer drugs.

Expert Opinion On Drug Metabolism & Toxicology

Huang, Kevin M KM; Uddin, Muhammad Erfan ME; DiGiacomo, Duncan D; Lustberg, Maryam B MB; Hu, Shuiying S; Sparreboom, Alex A

Publication Date: 2020-06

Variant appearance in text: rs2289669

PubMed Link: 32276560

Variant Present in the following documents:

• Main text

View BVdb publication page

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A Protocol for the Study of Polymorphisms and Response to Metformin in Patients with Type 2 Diabetes in Trinidad.

Ethnicity & Disease

Clement, Yuri Y; Singh, Shamjeet S; Motilal, Shastri S; Maharaj, Rohan R; Nunez-Smith, Marcella M

Publication Date: 2020

Variant appearance in text: rs2289669

PubMed Link: 32269463

Variant Present in the following documents:

• Main text

View BVdb publication page

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Effect of plasma membrane monoamine transporter genetic variants on pharmacokinetics of metformin in humans.

Translational And Clinical Pharmacology

Moon, Seol Ju SJ; Oh, Jaeseong J; Lee, Seung Hwan SH; Choi, Yewon Y; Yu, Kyung-Sang KS; Chung, Jae-Yong JY

Publication Date: 2018-06

Variant appearance in text: SLC47A1: 922-158G>A; rs2289669

PubMed Link: 32055553

Variant Present in the following documents:

• Main text
• tcp-26-79.pdf

View BVdb publication page

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Drug-drug-gene interactions and adverse drug reactions.

The Pharmacogenomics Journal

Malki, Mustafa Adnan MA; Pearson, Ewan Robert ER

Publication Date: 2020-06

Variant appearance in text: rs2289669

PubMed Link: 31792369

Variant Present in the following documents:

• Main text
• 41397_2019_Article_122.pdf

View BVdb publication page

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Common Variants in 22 Genes Regulate Response to Metformin Intervention in Children with Obesity: A Pharmacogenetic Study of a Randomized Controlled Trial.

Journal Of Clinical Medicine

Anguita-Ruiz, Augusto A; Pastor-Villaescusa, Belén B; Leis, Rosaura R; Bueno, Gloria G; Hoyos, Raúl R; Vázquez-Cobela, Rocío R; Latorre-Millán, Miriam M; Cañete, M Dolores MD; Caballero-Villarraso, Javier J; Gil, Ángel Á; Cañete, Ramón R; Aguilera, Concepción M CM

Publication Date: 2019-09-16

Variant appearance in text: rs2289669

PubMed Link: 31527397

Variant Present in the following documents:

• Main text

View BVdb publication page

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When drug treatments bias genetic studies: Mediation and interaction.

Plos One

Schmidt, Amand F AF; Heerspink, Hiddo J L HJL; Denig, Petra P; Finan, Chris C; Groenwold, Rolf H H RHH

Publication Date: 2019

Variant appearance in text: rs2289669

PubMed Link: 31461463

Variant Present in the following documents:

• pone.0221209.s001.pdf

View BVdb publication page

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Genetic Variants as Predictive Markers for Ototoxicity and Nephrotoxicity in Patients with Locally Advanced Head and Neck Cancer Treated with Cisplatin-Containing Chemoradiotherapy (The PRONE Study).

Cancers

Driessen, Chantal M CM; Ham, Janneke C JC; Te Loo, Maroeska M; van Meerten, Esther E; van Lamoen, Maurits M; Hakobjan, Marina H MH; Takes, Robert P RP; van der Graaf, Winette T WT; Kaanders, Johannes H JH; Coenen, Marieke J H MJH; van Herpen, Carla M CM

Publication Date: 2019-04-17

Variant appearance in text: rs2289669

PubMed Link: 30999660

Variant Present in the following documents:

• Main text
• cancers-11-00551.pdf

View BVdb publication page

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Allele Frequency of SLC22A1 Met420del Metformin Main Transporter Encoding Gene among Javanese-Indonesian Population.

Open Access Macedonian Journal Of Medical Sciences

Ningrum, Vitarani DA VD; Istikharah, Rochmy R; Firmansyah, Rheza R

Publication Date: 2019-02-15

Variant appearance in text: rs2289669

PubMed Link: 30834005

Variant Present in the following documents:

• OAMJMS-7-378.pdf

View BVdb publication page

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Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine.

Diabetes/Metabolism Research And Reviews

Mannino, Gaia Chiara GC; Andreozzi, Francesco F; Sesti, Giorgio G

Publication Date: 2019-03

Variant appearance in text: rs2289669

PubMed Link: 30515958

Variant Present in the following documents:

• Main text

View BVdb publication page

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OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans.

Scientific Reports

Kwon, Eun Young EY; Chung, Jae-Yong JY; Park, Hyo Jin HJ; Kim, Bo Min BM; Kim, Minsuk M; Choi, Ji Ha JH

Publication Date: 2018-11-16

Variant appearance in text: rs2289669

PubMed Link: 30446679

Variant Present in the following documents:

• Main text
• 41598_2018_Article_35322.pdf
• 41598_2018_35322_MOESM1_ESM.pdf

View BVdb publication page

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Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review.

Frontiers In Pharmacology

Zazuli, Zulfan Z; Vijverberg, Susanne S; Slob, Elise E; Liu, Geoffrey G; Carleton, Bruce B; Veltman, Joris J; Baas, Paul P; Masereeuw, Rosalinde R; Maitland-van der Zee, Anke-Hilse AH

Publication Date: 2018

Variant appearance in text: rs2289669

PubMed Link: 30319427

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association between polymorphisms in SLC15A1 and PLA2G16 genes and development of obesity in Chinese subjects.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy

Wang, Chun-Yang CY; Liu, Shu S; Xie, Xiao-Nv XN; Luo, Zhi-Ying ZY; Yang, Li L; Tan, Zhi-Rong ZR

Publication Date: 2018

Variant appearance in text: rs2289669

PubMed Link: 30174451

Variant Present in the following documents:

• dmso-11-439.pdf

View BVdb publication page

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Genetic polymorphisms of organic cation transporter 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes: A systematic review.

Medicine

Mofo Mato, Edith Pascale EP; Guewo-Fokeng, Magellan M; Essop, M Faadiel MF; Owira, Peter Mark Oroma PMO

Publication Date: 2018-07

Variant appearance in text: rs2289669

PubMed Link: 29979413

Variant Present in the following documents:

• medi-97-e11349.pdf

View BVdb publication page

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Increased Metformin Clearance in Overweight and Obese Adolescents: A Pharmacokinetic Substudy of a Randomized Controlled Trial.

Paediatric Drugs

van Rongen, Anne A; van der Aa, Marloes P MP; Matic, Maja M; van Schaik, Ron H N RHN; Deneer, Vera H M VHM; van der Vorst, Marja M MM; Knibbe, Catherijne A J CAJ

Publication Date: 2018-08

Variant appearance in text: rs2289669

PubMed Link: 29748932

Variant Present in the following documents:

• Main text
• 40272_2018_Article_293.pdf

View BVdb publication page

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Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.

Clinical Pharmacology And Therapeutics

Yee, Sook Wah SW; Brackman, Deanna J DJ; Ennis, Elizabeth A EA; Sugiyama, Yuichi Y; Kamdem, Landry K LK; Blanchard, Rebecca R; Galetin, Aleksandra A; Zhang, Lei L; Giacomini, Kathleen M KM

Publication Date: 2018-11

Variant appearance in text: rs2289669

PubMed Link: 29679469

Variant Present in the following documents:

• Main text

View BVdb publication page

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Precision medicine in diabetes prevention, classification and management.

Journal Of Diabetes Investigation

Xie, Fangying F; Chan, Juliana Cn JC; Ma, Ronald Cw RC

Publication Date: 2018-09

Variant appearance in text: rs2289669

PubMed Link: 29499103

Variant Present in the following documents:

• Main text

View BVdb publication page

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Influence of pharmacogenetic polymorphisms and demographic variables on metformin pharmacokinetics in an admixed Brazilian cohort.

British Journal Of Clinical Pharmacology

Santoro, Ana Beatriz AB; Botton, Mariana Rodrigues MR; Struchiner, Claudio José CJ; Suarez-Kurtz, Guilherme G

Publication Date: 2018-05

Variant appearance in text: rs2289669

PubMed Link: 29352482

Variant Present in the following documents:

• Main text

View BVdb publication page

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