Publications:

---

Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine.

Diabetes/Metabolism Research And Reviews

Mannino, Gaia Chiara GC; Andreozzi, Francesco F; Sesti, Giorgio G

Publication Date: 2019-03

Variant appearance in text: SLC47A2: Pro162Leu; rs146901447

PubMed Link: 30515958

Variant Present in the following documents:

• Main text
• DMRR-35-na.pdf

View BVdb publication page

---

An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

The Pharmacogenomics Journal

Zhou, Yitian Y; Mkrtchian, Souren S; Kumondai, Masaki M; Hiratsuka, Masahiro M; Lauschke, Volker M VM

Publication Date: 2019-04

Variant appearance in text: SLC47A2: P162L; rs146901447

PubMed Link: 30206299

Variant Present in the following documents:

• 41397_2018_44_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.

Clinical Pharmacology And Therapeutics

Yee, Sook Wah SW; Brackman, Deanna J DJ; Ennis, Elizabeth A EA; Sugiyama, Yuichi Y; Kamdem, Landry K LK; Blanchard, Rebecca R; Galetin, Aleksandra A; Zhang, Lei L; Giacomini, Kathleen M KM

Publication Date: 2018-11

Variant appearance in text: MATE2: P162L

PubMed Link: 29679469

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics

Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR

Publication Date: 2017-03

Variant appearance in text: SLC47A2: Pro162Leu; rs146901447

PubMed Link: 27984508

Variant Present in the following documents:

• fpc-27-089.pdf
• fpc-27-089-s006.xlsx, sheet 2

View BVdb publication page

---

An update on the pharmacogenomics of metformin: progress, problems and potential.

Pharmacogenomics

Todd, Jennifer N JN; Florez, Jose C JC

Publication Date: 2014-03

Variant appearance in text: SLC47A2: P162L

PubMed Link: 24624919

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.

The Aaps Journal

Motohashi, Hideyuki H; Inui, Ken-ichi K

Publication Date: 2013-04

Variant appearance in text: MATE2-K: 485C>T

PubMed Link: 23435786

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin.

Clinical Pharmacology And Therapeutics

Stocker, S L SL; Morrissey, K M KM; Yee, S W SW; Castro, R A RA; Xu, L L; Dahlin, A A; Ramirez, A H AH; Roden, D M DM; Wilke, R A RA; McCarty, C A CA; Davis, R L RL; Brett, C M CM; Giacomini, K M KM

Publication Date: 2013-02

Variant appearance in text: MATE2: 485C>T

PubMed Link: 23267855

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A common 5'-UTR variant in MATE2-K is associated with poor response to metformin.

Clinical Pharmacology And Therapeutics

Choi, J H JH; Yee, S W SW; Ramirez, A H AH; Morrissey, K M KM; Jang, G H GH; Joski, P J PJ; Mefford, J A JA; Hesselson, S E SE; Schlessinger, A A; Jenkins, G G; Castro, R A RA; Johns, S J SJ; Stryke, D D; Sali, A A; Ferrin, T E TE; Witte, J S JS; Kwok, P-Y PY; Roden, D M DM; Wilke, R A RA; McCarty, C A CA; Davis, R L RL; Giacomini, K M KM

Publication Date: 2011-11

Variant appearance in text: MATE2-K: 485C>T

PubMed Link: 21956618

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic variation in drug transporters in ethnic populations.

Clinical Pharmacology And Therapeutics

Cropp, C D CD; Yee, S W SW; Giacomini, K M KM

Publication Date: 2008-09

Variant appearance in text: MATE2-K: Pro162Leu

PubMed Link: 18528433

Variant Present in the following documents:

• Main text

View BVdb publication page

---