SLC6A4 c.-220-881C>T

Variant ID: 17-28550814-G-A

NM_001045.6(SLC6A4):c.-220-881C>T

This variant was identified in 24 publications

View GRCh38 version.




Publications:


Emotional dysregulation, alexithymia and neuroticism: a systematic review on the genetic basis of a subset of psychological traits.

Psychiatric Genetics
Castellini, Giovanni G; Merola, Giuseppe Pierpaolo GP; Baccaredda, Ottone Boy OB; Pecoraro, Vincenzo V; Bozza, Bernardo B; Cassioli, Emanuele E; Rossi, Eleonora E; Bessi, Valentina V; Sorbi, Sandro S; Nacmias, Benedetta B; Ricca, Valdo V
Publication Date: 2022-12-20

Variant appearance in text: rs2020936
PubMed Link: 36729042
Variant Present in the following documents:
  • Main text
  • pg-33-79.pdf
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The alternative serotonin transporter promoter P2 impacts gene function in females with irritable bowel syndrome.

Journal Of Cellular And Molecular Medicine
Mohr, Sandra S; Fritz, Nikola N; Hammer, Christian C; Martínez, Cristina C; Berens, Sabrina S; Schmitteckert, Stefanie S; Wahl, Verena V; Schmidt, Malin M; Houghton, Lesley A LA; Goebel-Stengel, Miriam M; Kabisch, Maria M; Götze, Dorothea D; Milovač, Irina I; D'Amato, Mauro M; Zheng, Tenghao T; Röth, Ralph R; Mönnikes, Hubert H; Engel, Felicitas F; Gauss, Annika A; Tesarz, Jonas J; Raithel, Martin M; Andresen, Viola V; Frieling, Thomas T; Keller, Jutta J; Pehl, Christian C; Stein-Thöringer, Christoph C; Clarke, Gerard G; Kennedy, Paul J PJ; Cryan, John F JF; Dinan, Timothy G TG; Quigley, Eamonn M M EMM; Spiller, Robin R; Beltrán, Caroll C; Madrid, Ana María AM; Torres, Verónica V; Pérez de Arce, Edith E; Herzog, Wolfgang W; Mayer, Emeran A EA; Sayuk, Gregory G; Gazouli, Maria M; Karamanolis, George G; Kapur-Pojskič, Lejla L; Bustamante, Mariona M; Rabionet, Raquel R; Estivil, Xavier X; Franke, André A; Lieb, Wolfgang W; Boeckxstaens, Guy G; Wouters, Mira M MM; Simrén, Magnus M; Rappold, Gudrun A GA; Vicario, Maria M; Santos, Javier J; Schaefert, Rainer R; Lorenzo-Bermejo, Justo J; Niesler, Beate B
Publication Date: 2021-08

Variant appearance in text: rs2020936
PubMed Link: 34165249
Variant Present in the following documents:
  • Main text
  • JCMM-25-8047.pdf
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Abdominal pain in patients with inflammatory bowel disease: association with single-nucleotide polymorphisms prevalent in irritable bowel syndrome and clinical management.

Bmc Gastroenterology
Ledergerber, Martina M; Lang, Brian M BM; Heinrich, Henriette H; Biedermann, Luc L; Begré, Stefan S; Zeitz, Jonas J; Krupka, Niklas N; Rickenbacher, Andreas A; Turina, Matthias M; Greuter, Thomas T; Schreiner, Philipp P; Roth, René R; Siebenhüner, Alexander A; Vavricka, Stephan R SR; Rogler, Gerhard G; Beerenwinkel, Niko N; Misselwitz, Benjamin B; ,
Publication Date: 2021-02-05

Variant appearance in text: rs2020936
PubMed Link: 33546600
Variant Present in the following documents:
  • Main text
  • 12876_2021_Article_1622.pdf
View BVdb publication page



Genetic Variation and Autism: A Field Synopsis and Systematic Meta-Analysis.

Brain Sciences
Lee, Jinhee J; Son, Min Ji MJ; Son, Chei Yun CY; Jeong, Gwang Hun GH; Lee, Keum Hwa KH; Lee, Kwang Seob KS; Ko, Younhee Y; Kim, Jong Yeob JY; Lee, Jun Young JY; Radua, Joaquim J; Eisenhut, Michael M; Gressier, Florence F; Koyanagi, Ai A; Stubbs, Brendon B; Solmi, Marco M; Rais, Theodor B TB; Kronbichler, Andreas A; Dragioti, Elena E; Vasconcelos, Daniel Fernando Pereira DFP; Silva, Felipe Rodolfo Pereira da FRPD; Tizaoui, Kalthoum K; Brunoni, André Russowsky AR; Carvalho, Andre F AF; Cargnin, Sarah S; Terrazzino, Salvatore S; Stickley, Andrew A; Smith, Lee L; Thompson, Trevor T; Shin, Jae Il JI; Fusar-Poli, Paolo P
Publication Date: 2020-09-30

Variant appearance in text: rs2020936
PubMed Link: 33007889
Variant Present in the following documents:
  • Main text
  • brainsci-10-00692.pdf
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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs2020936
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
View BVdb publication page



Genetic profile and patient-reported outcomes in chronic obstructive pulmonary disease: A systematic review.

Plos One
Melro, Hélder H; Gomes, Jorge J; Moura, Gabriela G; Marques, Alda A
Publication Date: 2018

Variant appearance in text: rs2020936
PubMed Link: 29927965
Variant Present in the following documents:
  • Main text
  • pone.0198920.pdf
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Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders.

Neural Plasticity
Jeanneteau, Freddy F; Arango-Lievano, Margarita M
Publication Date: 2016

Variant appearance in text: rs2020936
PubMed Link: 26885402
Variant Present in the following documents:
  • Main text
  • NP2016-3985063.pdf
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A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.

Molecular Autism
Warrier, Varun V; Chee, Vivienne V; Smith, Paula P; Chakrabarti, Bhismadev B; Baron-Cohen, Simon S
Publication Date: 2015

Variant appearance in text: rs2020936
PubMed Link: 26322220
Variant Present in the following documents:
  • Main text
  • 13229_2015_Article_41.pdf
  • 13229_2015_41_MOESM1_ESM.pdf
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Validation of candidate anxiety disorder genes using a carbon dioxide challenge task.

Biological Psychology
Savage, Jeanne E JE; McMichael, Omari O; Gorlin, Eugenia I EI; Beadel, Jessica R JR; Teachman, Bethany B; Vladimirov, Vladimir I VI; Hettema, John M JM; Roberson-Nay, Roxann R
Publication Date: 2015-07

Variant appearance in text: rs2020936
PubMed Link: 25913301
Variant Present in the following documents:
  • Main text
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Direct, indirect and pleiotropic effects of candidate genes on internalizing disorder psychopathology.

Psychological Medicine
Hettema, J M JM; Chen, X X; Sun, C C; Brown, T A TA
Publication Date: 2015-07

Variant appearance in text: rs2020936
PubMed Link: 25702797
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association study of serotonin transporter SLC6A4 gene with Chinese Han irritable bowel syndrome.

Plos One
Yuan, Jing J; Kang, ChuanYuan C; Wang, Min M; Wang, Qiang Q; Li, PeiKai P; Liu, Hua H; Hou, Yu Y; Su, Ping P; Yang, Fan F; Wei, YuJun Y; Yang, JianZhong J
Publication Date: 2014

Variant appearance in text: rs2020936
PubMed Link: 24392134
Variant Present in the following documents:
  • Main text
  • pone.0084414.pdf
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Evidence for single nucleotide polymorphisms and their association with bipolar disorder.

Neuropsychiatric Disease And Treatment
Szczepankiewicz, Aleksandra A
Publication Date: 2013

Variant appearance in text: rs2020936
PubMed Link: 24143106
Variant Present in the following documents:
  • Main text
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A preliminary examination of how serotonergic polymorphisms influence brain response following an adolescent cannabis intervention.

Psychiatry Research
Feldstein Ewing, Sarah W SW; Mead, Hilary K HK; Yezhuvath, Uma U; Dewitt, Sam S; Hutchison, Kent E KE; Filbey, Francesca M FM
Publication Date: 2012-11-30

Variant appearance in text: rs2020936
PubMed Link: 23217578
Variant Present in the following documents:
  • Main text
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Serotonin transporter gene (SLC6A4) variations are associated with poor survival in colorectal cancer patients.

Plos One
Savas, Sevtap S; Hyde, Angela A; Stuckless, Susan N SN; Parfrey, Patrick P; Younghusband, H Banfield HB; Green, Roger R
Publication Date: 2012

Variant appearance in text: rs2020936
PubMed Link: 22911682
Variant Present in the following documents:
  • Main text
  • pone.0038953.pdf
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Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder.

Bmc Psychiatry
Morey, Rajendra A RA; Hariri, Ahmad R AR; Gold, Andrea L AL; Hauser, Michael A MA; Munger, Heidi J HJ; Dolcos, Florin F; McCarthy, Gregory G
Publication Date: 2011-05-05

Variant appearance in text: rs2020936
PubMed Link: 21545724
Variant Present in the following documents:
  • Main text
  • 1471-244X-11-76.pdf
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Genetic influences on attention deficit hyperactivity disorder symptoms from age 2 to 3: a quantitative and molecular genetic investigation.

Bmc Psychiatry
Ilott, Nicholas E NE; Saudino, Kimberly J KJ; Asherson, Philip P
Publication Date: 2010-12-01

Variant appearance in text: rs2020936
PubMed Link: 21122117
Variant Present in the following documents:
  • Main text
  • 1471-244X-10-102.pdf
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A genetic study of ADHD and activity level in infancy.

Genes, Brain, And Behavior
Ilott, N N; Saudino, K J KJ; Wood, A A; Asherson, P P
Publication Date: 2010-04

Variant appearance in text: rs2020936
PubMed Link: 20039948
Variant Present in the following documents:
  • Main text
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Serotonin transporter gene, depressive symptoms, and interleukin-6.

Circulation. Cardiovascular Genetics
Su, Shaoyong S; Zhao, Jinying J; Bremner, J Douglas JD; Miller, Andrew H AH; Tang, Weining W; Bouzyk, Mark M; Snieder, Harold H; Novik, Olga O; Afzal, Nadeem N; Goldberg, Jack J; Vaccarino, Viola V
Publication Date: 2009-12

Variant appearance in text: rs2020936
PubMed Link: 20031642
Variant Present in the following documents:
  • Main text
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Accurate, Large-Scale Genotyping of 5HTTLPR and Flanking Single Nucleotide Polymorphisms in an Association Study of Depression, Anxiety, and Personality Measures.

Biological Psychiatry
Wray, Naomi R NR; James, Michael R MR; Gordon, Scott D SD; Dumenil, Troy T; Ryan, Leanne L; Coventry, William L WL; Statham, Dixie J DJ; Pergadia, Michele L ML; Madden, Pamela A F PA; Heath, Andrew C AC; Montgomery, Grant W GW; Martin, Nicholas G NG
Publication Date: 2009-09-01

Variant appearance in text: rs2020936
PubMed Link: 19541292
Variant Present in the following documents:
  • Main text
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Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Terracciano, Antonio A; Balaci, Lenuta L; Thayer, Jason J; Scally, Matthew M; Kokinos, Sarah S; Ferrucci, Luigi L; Tanaka, Toshiko T; Zonderman, Alan B AB; Sanna, Serena S; Olla, Nazario N; Zuncheddu, Maria Antonietta MA; Naitza, Silvia S; Busonero, Fabio F; Uda, Manuela M; Schlessinger, David D; Abecasis, Gonçalo R GR; Costa, Paul T PT
Publication Date: 2009-12-05

Variant appearance in text: rs2020936
PubMed Link: 19199283
Variant Present in the following documents:
  • Main text
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Serotonin transporter polymorphisms in patients with portopulmonary hypertension.

Chest
Roberts, Kari E KE; Fallon, Michael B MB; Krowka, Michael J MJ; Benza, Raymond L RL; Knowles, James A JA; Badesch, David B DB; Brown, Robert S RS; Taichman, Darren B DB; Trotter, James J; Zacks, Steven S; Horn, Evelyn M EM; Kawut, Steven M SM; ,
Publication Date: 2009-06

Variant appearance in text: rs2020936
PubMed Link: 19141529
Variant Present in the following documents:
  • Main text
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Panic disorder is associated with the serotonin transporter gene (SLC6A4) but not the promoter region (5-HTTLPR).

Molecular Psychiatry
Strug, L J LJ; Suresh, R R; Fyer, A J AJ; Talati, A A; Adams, P B PB; Li, W W; Hodge, S E SE; Gilliam, T C TC; Weissman, M M MM
Publication Date: 2010-02

Variant appearance in text: rs2020936
PubMed Link: 18663369
Variant Present in the following documents:
  • Main text
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Molecular genetics of the platelet serotonin system in first-degree relatives of patients with autism.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Cross, Sarah S; Kim, Soo-Jeong SJ; Weiss, Lauren A LA; Delahanty, Ryan J RJ; Sutcliffe, James S JS; Leventhal, Bennett L BL; Cook, Edwin H EH; Veenstra-Vanderweele, Jeremy J
Publication Date: 2008-01

Variant appearance in text: rs2020936
PubMed Link: 17406648
Variant Present in the following documents:
  • Main text
View BVdb publication page