Type 2 Diabetes-Related Variants Influence the Risk of Developing Prostate Cancer: A Population-Based Case-Control Study and Meta-Analysis.
Cancers
Sánchez-Maldonado, José Manuel JM; Collado, Ricardo R; Cabrera-Serrano, Antonio José AJ; Ter Horst, Rob R; Gálvez-Montosa, Fernando F; Robles-Fernández, Inmaculada I; Arenas-Rodríguez, Verónica V; Cano-Gutiérrez, Blanca B; Bakker, Olivier O; Bravo-Fernández, María Inmaculada MI; García-Verdejo, Francisco José FJ; López, José Antonio López JAL; Olivares-Ruiz, Jesús J; López-Nevot, Miguel Ángel MÁ; Fernández-Puerta, Laura L; Cózar-Olmo, José Manuel JM; Li, Yang Y; Netea, Mihai G MG; Jurado, Manuel M; Lorente, Jose Antonio JA; Sánchez-Rovira, Pedro P; Álvarez-Cubero, María Jesús MJ; Sainz, Juan J
A comprehensive analysis of the expression, epigenetic and genetic changes of HNF1B and ECI2 in 122 cases of high-grade serous ovarian carcinoma.
Oncology Letters
Němejcová, Kristýna K; Bártů, Michaela M; Hojný, Jan J; Hájková, Nikola N; Michálková, Romana R; Krkavcová, Eva E; Stružinská, Ivana I; Bui, Hiep Quang HQ; Dundr, Pavel P; Cibula, David D; Jirsová, Kateřina K
Analysis of expression, epigenetic, and genetic changes of HNF1B in 130 kidney tumours.
Scientific Reports
Bártů, Michaela M; Hojný, Jan J; Hájková, Nikola N; Michálková, Romana R; Krkavcová, Eva E; Hadravský, Ladislav L; Kleissnerová, Lenka L; Bui, Quang Hiep QH; Stružinská, Ivana I; Němejcová, Kristýna K; Čapoun, Otakar O; Šlemendová, Monika M; Dundr, Pavel P
A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease.
Esc Heart Failure
Molvin, John J; Jujic, Amra A; Nilsson, Peter M PM; Leosdottir, Margret M; Lindblad, Ulf U; Daka, Bledar B; Bennet, Louise L; Råstam, Lennart L; Lyssenko, Valeriya V; Magnusson, Martin M
Dietary and genetic risk scores and incidence of type 2 diabetes.
Genes & Nutrition
Ericson, Ulrika U; Hindy, George G; Drake, Isabel I; Schulz, Christina-Alexandra CA; Brunkwall, Louise L; Hellstrand, Sophie S; Almgren, Peter P; Orho-Melander, Marju M
Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.
Scientific Reports
Tsui, Nancy B Y NBY; Cheng, Gregory G; Chung, Teresa T; Lam, Christopher W K CWK; Yee, Anita A; Chung, Peter K C PKC; Kwan, Tsz-Ki TK; Ko, Elaine E; He, Daihai D; Wong, Wing-Tak WT; Lau, Johnson Y N JYN; Lau, Lok Ting LT; Fok, Manson M
Identification of Pleiotropic Cancer Susceptibility Variants from Genome-Wide Association Studies Reveals Functional Characteristics.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Wu, Yi-Hsuan YH; Graff, Rebecca E RE; Passarelli, Michael N MN; Hoffman, Joshua D JD; Ziv, Elad E; Hoffmann, Thomas J TJ; Witte, John S JS
Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.
The Journal Of Clinical Endocrinology And Metabolism
Billings, Liana K LK; Jablonski, Kathleen A KA; Warner, A Sofia AS; Cheng, Yu-Chien YC; McAteer, Jarred B JB; Tipton, Laura L; Shuldiner, Alan R AR; Ehrmann, David A DA; Manning, Alisa K AK; Dabelea, Dana D; Franks, Paul W PW; Kahn, Steven E SE; Pollin, Toni I TI; Knowler, William C WC; Altshuler, David D; Florez, Jose C JC; ,
HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer.
Oncotarget
Ross-Adams, Helen H; Ball, Stephen S; Lawrenson, Kate K; Halim, Silvia S; Russell, Roslin R; Wells, Claire C; Strand, Siri H SH; Ørntoft, Torben F TF; Larson, Melissa M; Armasu, Sebastian S; Massie, Charles E CE; Asim, Mohammad M; Mortensen, Martin M MM; Borre, Michael M; Woodfine, Kathryn K; Warren, Anne Y AY; Lamb, Alastair D AD; Kay, Jonathan J; Whitaker, Hayley H; Ramos-Montoya, Antonio A; Murrell, Adele A; Sørensen, Karina D KD; Fridley, Brooke L BL; Goode, Ellen L EL; Gayther, Simon A SA; Masters, John J; Neal, David E DE; Mills, Ian G IG
Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci.
American Journal Of Epidemiology
Clyde, Merlise A MA; Palmieri Weber, Rachel R; Iversen, Edwin S ES; Poole, Elizabeth M EM; Doherty, Jennifer A JA; Goodman, Marc T MT; Ness, Roberta B RB; Risch, Harvey A HA; Rossing, Mary Anne MA; Terry, Kathryn L KL; Wentzensen, Nicolas N; Whittemore, Alice S AS; Anton-Culver, Hoda H; Bandera, Elisa V EV; Berchuck, Andrew A; Carney, Michael E ME; Cramer, Daniel W DW; Cunningham, Julie M JM; Cushing-Haugen, Kara L KL; Edwards, Robert P RP; Fridley, Brooke L BL; Goode, Ellen L EL; Lurie, Galina G; McGuire, Valerie V; Modugno, Francesmary F; Moysich, Kirsten B KB; Olson, Sara H SH; Pearce, Celeste Leigh CL; Pike, Malcolm C MC; Rothstein, Joseph H JH; Sellers, Thomas A TA; Sieh, Weiva W; Stram, Daniel D; Thompson, Pamela J PJ; Vierkant, Robert A RA; Wicklund, Kristine G KG; Wu, Anna H AH; Ziogas, Argyrios A; Tworoger, Shelley S SS; Schildkraut, Joellen M JM; ,
Ryland, Georgina L GL; Doyle, Maria A MA; Goode, David D; Boyle, Samantha E SE; Choong, David Y H DY; Rowley, Simone M SM; Li, Jason J; , ; Bowtell, David D L DD; Tothill, Richard W RW; Campbell, Ian G IG; Gorringe, Kylie L KL
Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.
Human Molecular Genetics
Coetzee, Simon G SG; Shen, Howard C HC; Hazelett, Dennis J DJ; Lawrenson, Kate K; Kuchenbaecker, Karoline K; Tyrer, Jonathan J; Rhie, Suhn K SK; Levanon, Keren K; Karst, Alison A; Drapkin, Ronny R; Ramus, Susan J SJ; , ; Couch, Fergus J FJ; Offit, Kenneth K; Chenevix-Trench, Georgia G; Monteiro, Alvaro N A AN; Antoniou, Antonis A; Freedman, Matthew M; Coetzee, Gerhard A GA; Pharoah, Paul D P PD; Noushmehr, Houtan H; Gayther, Simon A SA; ,
Identification of six new susceptibility loci for invasive epithelial ovarian cancer.
Nature Genetics
Kuchenbaecker, Karoline B KB; Ramus, Susan J SJ; Tyrer, Jonathan J; Lee, Andrew A; Shen, Howard C HC; Beesley, Jonathan J; Lawrenson, Kate K; McGuffog, Lesley L; Healey, Sue S; Lee, Janet M JM; Spindler, Tassja J TJ; Lin, Yvonne G YG; Pejovic, Tanja T; Bean, Yukie Y; Li, Qiyuan Q; Coetzee, Simon S; Hazelett, Dennis D; Miron, Alexander A; Southey, Melissa M; Terry, Mary Beth MB; Goldgar, David E DE; Buys, Saundra S SS; Janavicius, Ramunas R; Dorfling, Cecilia M CM; van Rensburg, Elizabeth J EJ; Neuhausen, Susan L SL; Ding, Yuan Chun YC; Hansen, Thomas V O TV; Jønson, Lars L; Gerdes, Anne-Marie AM; Ejlertsen, Bent B; Barrowdale, Daniel D; Dennis, Joe J; Benitez, Javier J; Osorio, Ana A; Garcia, Maria Jose MJ; Komenaka, Ian I; Weitzel, Jeffrey N JN; Ganschow, Pamela P; Peterlongo, Paolo P; Bernard, Loris L; Viel, Alessandra A; Bonanni, Bernardo B; Peissel, Bernard B; Manoukian, Siranoush S; Radice, Paolo P; Papi, Laura L; Ottini, Laura L; Fostira, Florentia F; Konstantopoulou, Irene I; Garber, Judy J; 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Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Human Molecular Genetics
Painter, Jodie N JN; O'Mara, Tracy A TA; Batra, Jyotsna J; Cheng, Timothy T; Lose, Felicity A FA; Dennis, Joe J; Michailidou, Kyriaki K; Tyrer, Jonathan P JP; Ahmed, Shahana S; Ferguson, Kaltin K; Healey, Catherine S CS; Kaufmann, Susanne S; Hillman, Kristine M KM; Walpole, Carina C; Moya, Leire L; Pollock, Pamela P; Jones, Angela A; Howarth, Kimberley K; Martin, Lynn L; Gorman, Maggie M; Hodgson, Shirley S; , ; , ; De Polanco, Ma Magdalena Echeverry MM; Sans, Monica M; Carracedo, Angel A; Castellvi-Bel, Sergi S; Rojas-Martinez, Augusto A; Santos, Erika E; Teixeira, Manuel R MR; Carvajal-Carmona, Luis L; Shu, Xiao-Ou XO; Long, Jirong J; Zheng, Wei W; Xiang, Yong-Bing YB; , ; Montgomery, Grant W GW; Webb, Penelope M PM; Scott, Rodney J RJ; McEvoy, Mark M; Attia, John J; Holliday, Elizabeth E; Martin, Nicholas G NG; Nyholt, Dale R DR; Henders, Anjali K AK; Fasching, Peter A PA; Hein, Alexander A; Beckmann, Matthias W MW; Renner, Stefan P SP; Dörk, Thilo T; Hillemanns, Peter P; Dürst, Matthias M; Runnebaum, Ingo I; Lambrechts, Diether D; Coenegrachts, Lieve L; Schrauwen, Stefanie S; Amant, Frederic F; Winterhoff, Boris B; Dowdy, Sean C SC; Goode, Ellen L EL; Teoman, Attila A; Salvesen, Helga B HB; Trovik, Jone J; Njolstad, Tormund S TS; Werner, Henrica M J HM; Ashton, Katie K; Proietto, Tony T; Otton, Geoffrey G; Tzortzatos, Gerasimos G; Mints, Miriam M; Tham, Emma E; , ; Hall, Per P; Czene, Kamila K; Liu, Jianjun J; Li, Jingmei J; Hopper, John L JL; Southey, Melissa C MC; , ; Ekici, Arif B AB; Ruebner, Matthias M; Johnson, Nicola N; Peto, Julian J; Burwinkel, Barbara B; Marme, Frederik F; Brenner, Hermann H; Dieffenbach, Aida K AK; Meindl, Alfons A; Brauch, Hiltrud H; , ; Lindblom, Annika A; Depreeuw, Jeroen J; Moisse, Matthieu M; Chang-Claude, Jenny J; Rudolph, Anja A; Couch, Fergus J FJ; Olson, Janet E JE; Giles, Graham G GG; Bruinsma, Fiona F; Cunningham, Julie M JM; Fridley, Brooke L BL; Børresen-Dale, Anne-Lise AL; Kristensen, Vessela N VN; Cox, Angela A; Swerdlow, Anthony J AJ; Orr, Nicholas N; Bolla, Manjeet K MK; Wang, Qin Q; Weber, Rachel Palmieri RP; Chen, Zhihua Z; Shah, Mitul M; French, Juliet D JD; Pharoah, Paul D P PD; Dunning, Alison M AM; Tomlinson, Ian I; Easton, Douglas F DF; Edwards, Stacey L SL; Thompson, Deborah J DJ; Spurdle, Amanda B AB
Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent.
Plos One
Hassanali, Neelam N; De Silva, N Maneka G NM; Robertson, Neil N; Rayner, N William NW; Barrett, Amy A; Bennett, Amanda J AJ; Groves, Christopher J CJ; Matthews, David R DR; Katulanda, Prasad P; Frayling, Timothy M TM; McCarthy, Mark I MI
RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation.
Plos One
Haney, Steven S; Zhao, Juan J; Tiwari, Shiwani S; Eng, Kurt K; Guey, Lin T LT; Tien, Eric E
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Nature Genetics
Pharoah, Paul D P PD; Tsai, Ya-Yu YY; Ramus, Susan J SJ; Phelan, Catherine M CM; Goode, Ellen L EL; Lawrenson, Kate K; Buckley, Melissa M; Fridley, Brooke L BL; Tyrer, Jonathan P JP; Shen, Howard H; Weber, Rachel R; Karevan, Rod R; Larson, Melissa C MC; Song, Honglin H; Tessier, Daniel C DC; Bacot, François F; Vincent, Daniel D; Cunningham, Julie M JM; Dennis, Joe J; Dicks, Ed E; , ; , ; Aben, Katja K KK; Anton-Culver, Hoda H; Antonenkova, Natalia N; Armasu, Sebastian M SM; Baglietto, Laura L; Bandera, Elisa V EV; Beckmann, Matthias W MW; Birrer, Michael J MJ; Bloom, Greg G; Bogdanova, Natalia N; Brenton, James D JD; Brinton, Louise A LA; Brooks-Wilson, Angela A; Brown, Robert R; Butzow, Ralf R; Campbell, Ian I; Carney, Michael E ME; Carvalho, Renato S RS; Chang-Claude, Jenny J; Chen, Y Anne YA; Chen, Zhihua Z; Chow, Wong-Ho WH; Cicek, Mine S MS; Coetzee, Gerhard G; Cook, Linda S LS; Cramer, Daniel W DW; Cybulski, Cezary C; Dansonka-Mieszkowska, Agnieszka A; Despierre, Evelyn E; Doherty, Jennifer A JA; Dörk, Thilo T; du Bois, Andreas A; Dürst, Matthias M; Eccles, Diana D; Edwards, Robert R; Ekici, Arif B AB; Fasching, Peter A PA; Fenstermacher, David D; Flanagan, James J; Gao, Yu-Tang YT; Garcia-Closas, Montserrat M; Gentry-Maharaj, Aleksandra A; Giles, Graham G; Gjyshi, Anxhela A; Gore, Martin M; Gronwald, Jacek J; Guo, Qi Q; Halle, Mari K MK; Harter, Philipp P; Hein, Alexander A; Heitz, Florian F; Hillemanns, Peter P; Hoatlin, Maureen M; Høgdall, Estrid E; Høgdall, Claus K CK; Hosono, Satoyo S; Jakubowska, Anna A; Jensen, Allan A; Kalli, Kimberly R KR; Karlan, Beth Y BY; Kelemen, Linda E LE; Kiemeney, Lambertus A LA; Kjaer, Susanne Krüger SK; Konecny, Gottfried E GE; Krakstad, Camilla C; Kupryjanczyk, Jolanta J; Lambrechts, Diether D; Lambrechts, Sandrina S; Le, Nhu D ND; Lee, Nathan N; Lee, Janet J; Leminen, Arto A; Lim, Boon Kiong BK; Lissowska, Jolanta J; Lubiński, Jan J; Lundvall, Lene L; Lurie, Galina G; Massuger, Leon F A G LF; Matsuo, Keitaro K; McGuire, Valerie V; McLaughlin, John R JR; Menon, Usha U; Modugno, Francesmary F; Moysich, Kirsten B KB; Nakanishi, Toru T; Narod, Steven A SA; Ness, Roberta B RB; Nevanlinna, Heli H; Nickels, Stefan S; Noushmehr, Houtan H; Odunsi, Kunle K; Olson, Sara S; Orlow, Irene I; Paul, James J; Pejovic, Tanja T; Pelttari, Liisa M LM; Permuth-Wey, Jenny J; Pike, Malcolm C MC; Poole, Elizabeth M EM; Qu, Xiaotao X; Risch, Harvey A HA; Rodriguez-Rodriguez, Lorna L; Rossing, Mary Anne MA; Rudolph, Anja A; Runnebaum, Ingo I; Rzepecka, Iwona K IK; Salvesen, Helga B HB; Schwaab, Ira I; Severi, Gianluca G; Shen, Hui H; Shridhar, Vijayalakshmi V; Shu, Xiao-Ou XO; Sieh, Weiva W; Southey, Melissa C MC; Spellman, Paul P; Tajima, Kazuo K; Teo, Soo-Hwang SH; Terry, Kathryn L KL; Thompson, Pamela J PJ; Timorek, Agnieszka A; Tworoger, Shelley S SS; van Altena, Anne M AM; van den Berg, David D; Vergote, Ignace I; Vierkant, Robert A RA; Vitonis, Allison F AF; Wang-Gohrke, Shan S; Wentzensen, Nicolas N; Whittemore, Alice S AS; Wik, Elisabeth E; Winterhoff, Boris B; Woo, Yin Ling YL; Wu, Anna H AH; Yang, Hannah P HP; Zheng, Wei W; Ziogas, Argyrios A; Zulkifli, Famida F; Goodman, Marc T MT; Hall, Per P; Easton, Douglas F DF; Pearce, Celeste L CL; Berchuck, Andrew A; Chenevix-Trench, Georgia G; Iversen, Edwin E; Monteiro, Alvaro N A AN; Gayther, Simon A SA; Schildkraut, Joellen M JM; Sellers, Thomas A TA
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
Nature Communications
Shen, Hui H; Fridley, Brooke L BL; Song, Honglin H; Lawrenson, Kate K; Cunningham, Julie M JM; Ramus, Susan J SJ; Cicek, Mine S MS; Tyrer, Jonathan J; Stram, Douglas D; Larson, Melissa C MC; Köbel, Martin M; , ; Ziogas, Argyrios A; Zheng, Wei W; Yang, Hannah P HP; Wu, Anna H AH; Wozniak, Eva L EL; Woo, Yin Ling YL; Winterhoff, Boris B; Wik, Elisabeth E; Whittemore, Alice S AS; Wentzensen, Nicolas N; Weber, Rachel Palmieri RP; Vitonis, Allison F AF; Vincent, Daniel D; Vierkant, Robert A RA; Vergote, Ignace I; Van Den Berg, David D; Van Altena, Anne M AM; Tworoger, Shelley S SS; Thompson, Pamela J PJ; Tessier, Daniel C DC; Terry, Kathryn L KL; Teo, Soo-Hwang SH; Templeman, Claire C; Stram, Daniel O DO; Southey, Melissa C MC; Sieh, Weiva W; Siddiqui, Nadeem N; Shvetsov, Yurii B YB; Shu, Xiao-Ou XO; Shridhar, Viji V; Wang-Gohrke, Shan S; Severi, Gianluca G; Schwaab, Ira I; Salvesen, Helga B HB; Rzepecka, Iwona K IK; Runnebaum, Ingo B IB; Rossing, Mary Anne MA; Rodriguez-Rodriguez, Lorna L; Risch, Harvey A HA; Renner, Stefan P SP; Poole, Elizabeth M EM; Pike, Malcolm C MC; Phelan, Catherine M CM; Pelttari, Liisa M LM; Pejovic, Tanja T; Paul, James J; Orlow, Irene I; Omar, Siti Zawiah SZ; Olson, Sara H SH; Odunsi, Kunle K; Nickels, Stefan S; Nevanlinna, Heli H; Ness, Roberta B RB; Narod, Steven A SA; Nakanishi, Toru T; Moysich, Kirsten B KB; Monteiro, Alvaro N A AN; Moes-Sosnowska, Joanna J; Modugno, Francesmary F; Menon, Usha U; McLaughlin, John R JR; McGuire, Valerie V; Matsuo, Keitaro K; Adenan, Noor Azmi Mat NA; Massuger, Leon F A G LF; Lurie, Galina G; Lundvall, Lene L; Lubiński, Jan J; Lissowska, Jolanta J; Levine, Douglas A DA; Leminen, Arto A; Lee, Alice W AW; Le, Nhu D ND; Lambrechts, Sandrina S; Lambrechts, Diether D; Kupryjanczyk, Jolanta J; Krakstad, Camilla C; Konecny, Gottfried E GE; Kjaer, Susanne Krüger SK; Kiemeney, Lambertus A LA; Kelemen, Linda E LE; Keeney, Gary L GL; Karlan, Beth Y BY; Karevan, Rod R; Kalli, Kimberly R KR; Kajiyama, Hiroaki H; Ji, Bu-Tian BT; Jensen, Allan A; Jakubowska, Anna A; Iversen, Edwin E; Hosono, Satoyo S; Høgdall, Claus K CK; Høgdall, Estrid E; Hoatlin, Maureen M; Hillemanns, Peter P; Heitz, Florian F; Hein, Rebecca R; Harter, Philipp P; Halle, Mari K MK; Hall, Per P; Gronwald, Jacek J; Gore, Martin M; Goodman, Marc T MT; Giles, Graham G GG; Gentry-Maharaj, Aleksandra A; Garcia-Closas, Montserrat M; Flanagan, James M JM; Fasching, Peter A PA; Ekici, Arif B AB; Edwards, Robert R; Eccles, Diana D; Easton, Douglas F DF; Dürst, Matthias M; du Bois, Andreas A; Dörk, Thilo T; Doherty, Jennifer A JA; Despierre, Evelyn E; Dansonka-Mieszkowska, Agnieszka A; Cybulski, Cezary C; Cramer, Daniel W DW; Cook, Linda S LS; Chen, Xiaoqing X; Charbonneau, Bridget B; Chang-Claude, Jenny J; Campbell, Ian I; Butzow, Ralf R; Bunker, Clareann H CH; Brueggmann, Doerthe D; Brown, Robert R; Brooks-Wilson, Angela A; Brinton, Louise A LA; Bogdanova, Natalia N; Block, Matthew S MS; Benjamin, Elizabeth E; Beesley, Jonathan J; Beckmann, Matthias W MW; Bandera, Elisa V EV; Baglietto, Laura L; Bacot, François F; Armasu, Sebastian M SM; Antonenkova, Natalia N; Anton-Culver, Hoda H; Aben, Katja K KK; Liang, Dong D; Wu, Xifeng X; Lu, Karen K; Hildebrandt, Michelle A T MA; , ; , ; Schildkraut, Joellen M JM; Sellers, Thomas A TA; Huntsman, David D; Berchuck, Andrew A; Chenevix-Trench, Georgia G; Gayther, Simon A SA; Pharoah, Paul D P PD; Laird, Peter W PW; Goode, Ellen L EL; Pearce, Celeste Leigh CL
Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.
Journal Of Hypertension
de Miguel-Yanes, Jose M JM; Porneala, Bianca B; Pencina, Michael J MJ; Fox, Caroline S CS; Florez, Jose C JC; Siscovick, David S DS; Dupuis, Josée J; Meigs, James B JB
Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium.
American Journal Of Epidemiology
Machiela, Mitchell J MJ; Lindström, Sara S; Allen, Naomi E NE; Haiman, Christopher A CA; Albanes, Demetrius D; Barricarte, Aurelio A; Berndt, Sonja I SI; Bueno-de-Mesquita, H Bas HB; Chanock, Stephen S; Gaziano, J Michael JM; Gapstur, Susan M SM; Giovannucci, Edward E; Henderson, Brian E BE; Jacobs, Eric J EJ; Kolonel, Laurence N LN; Krogh, Vittorio V; Ma, Jing J; Stampfer, Meir J MJ; Stevens, Victoria L VL; Stram, Daniel O DO; Tjønneland, Anne A; Travis, Ruth R; Willett, Walter C WC; Hunter, David J DJ; Le Marchand, Loic L; Kraft, Peter P
Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children.
Bmc Medical Genetics
Bonilla, Carolina C; Lawlor, Debbie A DA; Ben-Shlomo, Yoav Y; Ness, Andrew R AR; Gunnell, David D; Ring, Susan M SM; Smith, George Davey GD; Lewis, Sarah J SJ
A genotype risk score predicts type 2 diabetes from young adulthood: the CARDIA study.
Diabetologia
Vassy, J L JL; Durant, N H NH; Kabagambe, E K EK; Carnethon, M R MR; Rasmussen-Torvik, L J LJ; Fornage, M M; Lewis, C E CE; Siscovick, D S DS; Meigs, J B JB
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
Plos Genetics
Perry, John R B JR; Voight, Benjamin F BF; Yengo, Loïc L; Amin, Najaf N; Dupuis, Josée J; Ganser, Martha M; Grallert, Harald H; Navarro, Pau P; Li, Man M; Qi, Lu L; Steinthorsdottir, Valgerdur V; Scott, Robert A RA; Almgren, Peter P; Arking, Dan E DE; Aulchenko, Yurii Y; Balkau, Beverley B; Benediktsson, Rafn R; Bergman, Richard N RN; Boerwinkle, Eric E; Bonnycastle, Lori L; Burtt, Noël P NP; Campbell, Harry H; Charpentier, Guillaume G; Collins, Francis S FS; Gieger, Christian C; Green, Todd T; Hadjadj, Samy S; Hattersley, Andrew T AT; Herder, Christian C; Hofman, Albert A; Johnson, Andrew D AD; Kottgen, Anna A; Kraft, Peter P; Labrune, Yann Y; Langenberg, Claudia C; Manning, Alisa K AK; Mohlke, Karen L KL; Morris, Andrew P AP; Oostra, Ben B; Pankow, James J; Petersen, Ann-Kristin AK; Pramstaller, Peter P PP; Prokopenko, Inga I; Rathmann, Wolfgang W; Rayner, William W; Roden, Michael M; Rudan, Igor I; Rybin, Denis D; Scott, Laura J LJ; Sigurdsson, Gunnar G; Sladek, Rob R; Thorleifsson, Gudmar G; Thorsteinsdottir, Unnur U; Tuomilehto, Jaakko J; Uitterlinden, Andre G AG; Vivequin, Sidonie S; Weedon, Michael N MN; Wright, Alan F AF; , ; , ; , ; Hu, Frank B FB; Illig, Thomas T; Kao, Linda L; Meigs, James B JB; Wilson, James F JF; Stefansson, Kari K; van Duijn, Cornelia C; Altschuler, David D; Morris, Andrew D AD; Boehnke, Michael M; McCarthy, Mark I MI; Froguel, Philippe P; Palmer, Colin N A CN; Wareham, Nicholas J NJ; Groop, Leif L; Frayling, Timothy M TM; Cauchi, Stéphane S
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
American Journal Of Human Genetics
Saxena, Richa R; Elbers, Clara C CC; Guo, Yiran Y; Peter, Inga I; Gaunt, Tom R TR; Mega, Jessica L JL; Lanktree, Matthew B MB; Tare, Archana A; Castillo, Berta Almoguera BA; Li, Yun R YR; Johnson, Toby T; Bruinenberg, Marcel M; Gilbert-Diamond, Diane D; Rajagopalan, Ramakrishnan R; Voight, Benjamin F BF; Balasubramanyam, Ashok A; Barnard, John J; Bauer, Florianne F; Baumert, Jens J; Bhangale, Tushar T; Böhm, Bernhard O BO; Braund, Peter S PS; Burton, Paul R PR; Chandrupatla, Hareesh R HR; Clarke, Robert R; Cooper-DeHoff, Rhonda M RM; Crook, Errol D ED; Davey-Smith, George G; Day, Ian N IN; de Boer, Anthonius A; de Groot, Mark C H MC; Drenos, Fotios F; Ferguson, Jane J; Fox, Caroline S CS; Furlong, Clement E CE; Gibson, Quince Q; Gieger, Christian C; Gilhuijs-Pederson, Lisa A LA; Glessner, Joseph T JT; Goel, Anuj A; Gong, Yan Y; Grant, Struan F A SF; Grobbee, Diederick E DE; Hastie, Claire C; Humphries, Steve E SE; Kim, Cecilia E CE; Kivimaki, Mika M; Kleber, Marcus M; Meisinger, Christa C; Kumari, Meena M; Langaee, Taimour Y TY; Lawlor, Debbie A DA; Li, Mingyao M; Lobmeyer, Maximilian T MT; Maitland-van der Zee, Anke-Hilse AH; Meijs, Matthijs F L MF; Molony, Cliona M CM; Morrow, David A DA; Murugesan, Gurunathan G; Musani, Solomon K SK; Nelson, Christopher P CP; Newhouse, Stephen J SJ; O'Connell, Jeffery R JR; Padmanabhan, Sandosh S; Palmen, Jutta J; Patel, Sanjey R SR; Pepine, Carl J CJ; Pettinger, Mary M; Price, Thomas S TS; Rafelt, Suzanne S; Ranchalis, Jane J; Rasheed, Asif A; Rosenthal, Elisabeth E; Ruczinski, Ingo I; Shah, Sonia S; Shen, Haiqing H; Silbernagel, Günther G; Smith, Erin N EN; Spijkerman, Annemieke W M AW; Stanton, Alice A; Steffes, Michael W MW; Thorand, Barbara B; Trip, Mieke M; van der Harst, Pim P; van der A, Daphne L DL; van Iperen, Erik P A EP; van Setten, Jessica J; van Vliet-Ostaptchouk, Jana V JV; Verweij, Niek N; Wolffenbuttel, Bruce H R BH; Young, Taylor T; Zafarmand, M Hadi MH; Zmuda, Joseph M JM; , ; , ; Boehnke, Michael M; Altshuler, David D; McCarthy, Mark M; Kao, W H Linda WH; Pankow, James S JS; Cappola, Thomas P TP; Sever, Peter P; Poulter, Neil N; Caulfield, Mark M; Dominiczak, Anna A; Shields, Denis C DC; Bhatt, Deepak L DL; Bhatt, Deepak D; Zhang, Li L; Curtis, Sean P SP; Danesh, John J; Casas, Juan P JP; van der Schouw, Yvonne T YT; Onland-Moret, N Charlotte NC; Doevendans, Pieter A PA; Dorn, Gerald W GW; Farrall, Martin M; FitzGerald, Garret A GA; Hamsten, Anders A; Hegele, Robert R; Hingorani, Aroon D AD; Hofker, Marten H MH; Huggins, Gordon S GS; Illig, Thomas T; Jarvik, Gail P GP; Johnson, Julie A JA; Klungel, Olaf H OH; Knowler, William C WC; Koenig, Wolfgang W; März, Winfried W; Meigs, James B JB; Melander, Olle O; Munroe, Patricia B PB; Mitchell, Braxton D BD; Bielinski, Susan J SJ; Rader, Daniel J DJ; Reilly, Muredach P MP; Rich, Stephen S SS; Rotter, Jerome I JI; Saleheen, Danish D; Samani, Nilesh J NJ; Schadt, Eric E EE; Shuldiner, Alan R AR; Silverstein, Roy R; Kottke-Marchant, Kandice K; Talmud, Philippa J PJ; Watkins, Hugh H; Asselbergs, Folkert W FW; Asselbergs, Folkert F; de Bakker, Paul I W PI; McCaffery, Jeanne J; Wijmenga, Cisca C; Sabatine, Marc S MS; Wilson, James G JG; Reiner, Alex A; Bowden, Donald W DW; Hakonarson, Hakon H; Siscovick, David S DS; Keating, Brendan J BJ
Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.
Diabetologia
Gupta, V V; Vinay, D G DG; Rafiq, S S; Kranthikumar, M V MV; Janipalli, C S CS; Giambartolomei, C C; Evans, D M DM; Mani, K R KR; Sandeep, M N MN; Taylor, A E AE; Kinra, S S; Sullivan, R M RM; Bowen, L L; Timpson, N J NJ; Smith, G D GD; Dudbridge, F F; Prabhakaran, D D; Ben-Shlomo, Y Y; Reddy, K S KS; Ebrahim, S S; Chandak, G R GR; ,
Large-scale fine mapping of the HNF1B locus and prostate cancer risk.
Human Molecular Genetics
Berndt, Sonja I SI; Sampson, Joshua J; Yeager, Meredith M; Jacobs, Kevin B KB; Wang, Zhaoming Z; Hutchinson, Amy A; Chung, Charles C; Orr, Nick N; Wacholder, Sholom S; Chatterjee, Nilanjan N; Yu, Kai K; Kraft, Peter P; Feigelson, Heather Spencer HS; Thun, Michael J MJ; Diver, W Ryan WR; Albanes, Demetrius D; Virtamo, Jarmo J; Weinstein, Stephanie S; Schumacher, Fredrick R FR; Cancel-Tassin, Geraldine G; Cussenot, Olivier O; Valeri, Antoine A; Andriole, Gerald L GL; Crawford, E David ED; Haiman, Christopher C; Henderson, Brian B; Kolonel, Laurence L; Le Marchand, Loic L; Siddiq, Afshan A; Riboli, Elio E; Travis, Ruth C RC; Kaaks, Rudolf R; Isaacs, William W; Isaacs, Sarah S; Wiley, Kathleen E KE; Gronberg, Henrik H; Wiklund, Fredrik F; Stattin, Pär P; Xu, Jianfeng J; Zheng, S Lilly SL; Sun, Jielin J; Vatten, Lars J LJ; Hveem, Kristian K; Njølstad, Inger I; Gerhard, Daniela S DS; Tucker, Margaret M; Hayes, Richard B RB; Hoover, Robert N RN; Fraumeni, Joseph F JF; Hunter, David J DJ; Thomas, Gilles G; Chanock, Stephen J SJ
Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.
Diabetes
Stančáková, Alena A; Paananen, Jussi J; Soininen, Pasi P; Kangas, Antti J AJ; Bonnycastle, Lori L LL; Morken, Mario A MA; Collins, Francis S FS; Jackson, Anne U AU; Boehnke, Michael L ML; Kuusisto, Johanna J; Ala-Korpela, Mika M; Laakso, Markku M
Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program.
Diabetes
Hivert, Marie-France MF; Jablonski, Kathleen A KA; Perreault, Leigh L; Saxena, Richa R; McAteer, Jarred B JB; Franks, Paul W PW; Hamman, Richard F RF; Kahn, Steven E SE; Haffner, Steven S; , ; Meigs, James B JB; Altshuler, David D; Knowler, William C WC; Florez, Jose C JC; ,
Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study.
Aging
Mooijaart, Simon P SP; van Heemst, Diana D; Noordam, Raymond R; Rozing, Maarten P MP; Wijsman, Carolien A CA; de Craen, Anton J M AJ; Westendorp, Rudi G J RG; Beekman, Marian M; Slagboom, P Eline PE
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.
Plos One
Bell, Christopher G CG; Finer, Sarah S; Lindgren, Cecilia M CM; Wilson, Gareth A GA; Rakyan, Vardhman K VK; Teschendorff, Andrew E AE; Akan, Pelin P; Stupka, Elia E; Down, Thomas A TA; Prokopenko, Inga I; Morison, Ian M IM; Mill, Jonathan J; Pidsley, Ruth R; , ; Deloukas, Panos P; Frayling, Timothy M TM; Hattersley, Andrew T AT; McCarthy, Mark I MI; Beck, Stephan S; Hitman, Graham A GA
Impact of positive family history and genetic risk variants on the incidence of diabetes: the Finnish Diabetes Prevention Study.
Diabetes Care
Uusitupa, Matti I MI; Stancáková, Alena A; Peltonen, Markku M; Eriksson, Johan G JG; Lindström, Jaana J; Aunola, Sirkka S; Ilanne-Parikka, Pirjo P; Keinänen-Kiukaanniemi, Sirkka S; Tuomilehto, Jaakko J; Laakso, Markku M
Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose.
Genetic Epidemiology
Rasmussen-Torvik, Laura J LJ; Alonso, Alvaro A; Li, Man M; Kao, Wen W; Köttgen, Anna A; Yan, Yu Y; Couper, David D; Boerwinkle, Eric E; Bielinski, Suzette J SJ; Pankow, James S JS
Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program.
Diabetes
Jablonski, Kathleen A KA; McAteer, Jarred B JB; de Bakker, Paul I W PI; Franks, Paul W PW; Pollin, Toni I TI; Hanson, Robert L RL; Saxena, Richa R; Fowler, Sarah S; Shuldiner, Alan R AR; Knowler, William C WC; Altshuler, David D; Florez, Jose C JC; ,
Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.
Bmc Medical Genomics
Parikh, Hemang H; Lyssenko, Valeriya V; Groop, Leif C LC
Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function.
Diabetes
Simonis-Bik, Annemarie M AM; Nijpels, Giel G; van Haeften, Timon W TW; Houwing-Duistermaat, Jeanine J JJ; Boomsma, Dorret I DI; Reiling, Erwin E; van Hove, Els C EC; Diamant, Michaela M; Kramer, Mark H H MH; Heine, Robert J RJ; Maassen, J Antonie JA; Slagboom, P Eline PE; Willemsen, Gonneke G; Dekker, Jacqueline M JM; Eekhoff, Elisabeth M EM; de Geus, Eco J EJ; 't Hart, Leen M LM