Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score.
Prostate Cancer And Prostatic Diseases
Huynh-Le, Minh-Phuong MP; Karunamuni, Roshan R; Fan, Chun Chieh CC; Asona, Lui L; Thompson, Wesley K WK; Martinez, Maria Elena ME; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z; Muir, Kenneth R KR; Lophatananon, Artitaya A; Schleutker, Johanna J; Pashayan, Nora N; Batra, Jyotsna J; Grönberg, Henrik H; Neal, David E DE; Nordestgaard, Børge G BG; Tangen, Catherine M CM; MacInnis, Robert J RJ; Wolk, Alicja A; Albanes, Demetrius D; Haiman, Christopher A CA; Travis, Ruth C RC; Blot, William J WJ; Stanford, Janet L JL; Mucci, Lorelei A LA; West, Catharine M L CML; Nielsen, Sune F SF; Kibel, Adam S AS; Cussenot, Olivier O; Berndt, Sonja I SI; Koutros, Stella S; Sørensen, Karina Dalsgaard KD; Cybulski, Cezary C; Grindedal, Eli Marie EM; Menegaux, Florence F; Park, Jong Y JY; Ingles, Sue A SA; Maier, Christiane C; Hamilton, Robert J RJ; Rosenstein, Barry S BS; Lu, Yong-Jie YJ; Watya, Stephen S; Vega, Ana A; Kogevinas, Manolis M; Wiklund, Fredrik F; Penney, Kathryn L KL; Huff, Chad D CD; Teixeira, Manuel R MR; Multigner, Luc L; Leach, Robin J RJ; Brenner, Hermann H; John, Esther M EM; Kaneva, Radka R; Logothetis, Christopher J CJ; Neuhausen, Susan L SL; De Ruyck, Kim K; Ost, Piet P; Razack, Azad A; Newcomb, Lisa F LF; Fowke, Jay H JH; Gamulin, Marija M; Abraham, Aswin A; Claessens, Frank F; Castelao, Jose Esteban JE; Townsend, Paul A PA; Crawford, Dana C DC; Petrovics, Gyorgy G; van Schaik, Ron H N RHN; Parent, Marie-Élise MÉ; Hu, Jennifer J JJ; Zheng, Wei W; , ; , ; , ; , ; , ; , ; , ; Mills, Ian G IG; Andreassen, Ole A OA; Dale, Anders M AM; Seibert, Tyler M TM
Pharmacogenetic association of diabetes-associated genetic risk score with rapid progression of coronary artery calcification following treatment with HMG-CoA-reductase inhibitors -results of the Heinz Nixdorf Recall Study.
Naunyn-Schmiedeberg'S Archives Of Pharmacology
Pechlivanis, Sonali S; Jung, Dominik D; Moebus, Susanne S; Lehmann, Nils N; Mahabadi, Amir A AA; Hoffmann, Per P; Erbel, Raimund R; Nöthen, Markus M MM; Bachmann, Hagen S HS
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations.
Nature Communications
Huynh-Le, Minh-Phuong MP; Fan, Chun Chieh CC; Karunamuni, Roshan R; Thompson, Wesley K WK; Martinez, Maria Elena ME; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z; Muir, Kenneth K; Schleutker, Johanna J; Pashayan, Nora N; Batra, Jyotsna J; Grönberg, Henrik H; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Martin, Richard M RM; Nielsen, Sune F SF; Nordestgaard, Børge G BG; Wiklund, Fredrik F; Tangen, Catherine M CM; Giles, Graham G GG; Wolk, Alicja A; Albanes, Demetrius D; Travis, Ruth C RC; Blot, William J WJ; Zheng, Wei W; Sanderson, Maureen M; Stanford, Janet L JL; Mucci, Lorelei A LA; West, Catharine M L CML; Kibel, Adam S AS; Cussenot, Olivier O; Berndt, Sonja I SI; Koutros, Stella S; Sørensen, Karina Dalsgaard KD; Cybulski, Cezary C; Grindedal, Eli Marie EM; Menegaux, Florence F; Khaw, Kay-Tee KT; Park, Jong Y JY; Ingles, Sue A SA; Maier, Christiane C; Hamilton, Robert J RJ; Thibodeau, Stephen N SN; Rosenstein, Barry S BS; Lu, Yong-Jie YJ; Watya, Stephen S; Vega, Ana A; Kogevinas, Manolis M; Penney, Kathryn L KL; Huff, Chad C; Teixeira, Manuel R MR; Multigner, Luc L; Leach, Robin J RJ; Cannon-Albright, Lisa L; Brenner, Hermann H; John, Esther M EM; Kaneva, Radka R; Logothetis, Christopher J CJ; Neuhausen, Susan L SL; De Ruyck, Kim K; Pandha, Hardev H; Razack, Azad A; Newcomb, Lisa F LF; Fowke, Jay H JH; Gamulin, Marija M; Usmani, Nawaid N; Claessens, Frank F; Gago-Dominguez, Manuela M; Townsend, Paul A PA; Bush, William S WS; Roobol, Monique J MJ; Parent, Marie-Élise MÉ; Hu, Jennifer J JJ; Mills, Ian G IG; Andreassen, Ole A OA; Dale, Anders M AM; Seibert, Tyler M TM; , ; , ; , ; , ; , ; , ; ,
Heritability and genome-wide association study of benign prostatic hyperplasia (BPH) in the eMERGE network.
Scientific Reports
Hellwege, Jacklyn N JN; Stallings, Sarah S; Torstenson, Eric S ES; Carroll, Robert R; Borthwick, Kenneth M KM; Brilliant, Murray H MH; Crosslin, David D; Gordon, Adam A; Hripcsak, George G; Jarvik, Gail P GP; Linneman, James G JG; Devi, Parimala P; Peissig, Peggy L PL; Sleiman, Patrick A M PAM; Hakonarson, Hakon H; Ritchie, Marylyn D MD; Verma, Shefali Setia SS; Shang, Ning N; Denny, Josh C JC; Roden, Dan M DM; Velez Edwards, Digna R DR; Edwards, Todd L TL
Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.
Nature Communications
Gudmundsson, Julius J; Sigurdsson, Jon K JK; Stefansdottir, Lilja L; Agnarsson, Bjarni A BA; Isaksson, Helgi J HJ; Stefansson, Olafur A OA; Gudjonsson, Sigurjon A SA; Gudbjartsson, Daniel F DF; Masson, Gisli G; Frigge, Michael L ML; Stacey, Simon N SN; Sulem, Patrick P; Halldorsson, Gisli H GH; Tragante, Vinicius V; Holm, Hilma H; Eyjolfsson, Gudmundur I GI; Sigurdardottir, Olof O; Olafsson, Isleifur I; Jonsson, Thorvaldur T; Jonsson, Eirikur E; Barkardottir, Rosa B RB; Hilmarsson, Rafn R; Asselbergs, Folkert W FW; Geirsson, Gudmundur G; Thorsteinsdottir, Unnur U; Rafnar, Thorunn T; Thorleifsson, Gudmar G; Stefansson, Kari K
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
Nature Communications
Dadaev, Tokhir T; Saunders, Edward J EJ; Newcombe, Paul J PJ; Anokian, Ezequiel E; Leongamornlert, Daniel A DA; Brook, Mark N MN; Cieza-Borrella, Clara C; Mijuskovic, Martina M; Wakerell, Sarah S; Olama, Ali Amin Al AAA; Schumacher, Fredrick R FR; Berndt, Sonja I SI; Benlloch, Sara S; Ahmed, Mahbubl M; Goh, Chee C; Sheng, Xin X; Zhang, Zhuo Z; Muir, Kenneth K; Govindasami, Koveela K; Lophatananon, Artitaya A; Stevens, Victoria L VL; Gapstur, Susan M SM; Carter, Brian D BD; Tangen, Catherine M CM; Goodman, Phyllis P; Thompson, Ian M IM; Batra, Jyotsna J; Chambers, Suzanne S; Moya, Leire L; Clements, Judith J; Horvath, Lisa L; Tilley, Wayne W; Risbridger, Gail G; Gronberg, Henrik H; Aly, Markus M; Nordström, Tobias T; Pharoah, Paul P; Pashayan, Nora N; Schleutker, Johanna J; Tammela, Teuvo L J TLJ; Sipeky, Csilla C; Auvinen, Anssi A; Albanes, Demetrius D; Weinstein, Stephanie S; Wolk, Alicja A; Hakansson, Niclas N; West, Catharine C; Dunning, Alison M AM; Burnet, Neil N; Mucci, Lorelei L; Giovannucci, Edward E; Andriole, Gerald G; Cussenot, Olivier O; Cancel-Tassin, Géraldine G; Koutros, Stella S; Freeman, Laura E Beane LEB; Sorensen, Karina Dalsgaard KD; Orntoft, Torben Falck TF; Borre, Michael M; Maehle, Lovise L; Grindedal, Eli Marie EM; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Martin, Richard M RM; Travis, Ruth C RC; Key, Tim J TJ; Hamilton, Robert J RJ; Fleshner, Neil E NE; Finelli, Antonio A; Ingles, Sue Ann SA; Stern, Mariana C MC; Rosenstein, Barry B; Kerns, Sarah S; Ostrer, Harry H; Lu, Yong-Jie YJ; Zhang, Hong-Wei HW; Feng, Ninghan N; Mao, Xueying X; Guo, Xin X; Wang, Guomin G; Sun, Zan Z; Giles, Graham G GG; Southey, Melissa C MC; MacInnis, Robert J RJ; FitzGerald, Liesel M LM; Kibel, Adam S AS; Drake, Bettina F BF; Vega, Ana A; Gómez-Caamaño, Antonio A; Fachal, Laura L; Szulkin, Robert R; Eklund, Martin M; Kogevinas, Manolis M; Llorca, Javier J; Castaño-Vinyals, Gemma G; Penney, Kathryn L KL; Stampfer, Meir M; Park, Jong Y JY; Sellers, Thomas A TA; Lin, Hui-Yi HY; Stanford, Janet L JL; Cybulski, Cezary C; Wokolorczyk, Dominika D; Lubinski, Jan J; Ostrander, Elaine A EA; Geybels, Milan S MS; Nordestgaard, Børge G BG; Nielsen, Sune F SF; Weisher, Maren M; Bisbjerg, Rasmus R; Røder, Martin Andreas MA; Iversen, Peter P; Brenner, Hermann H; Cuk, Katarina K; Holleczek, Bernd B; Maier, Christiane C; Luedeke, Manuel M; Schnoeller, Thomas T; Kim, Jeri J; Logothetis, Christopher J CJ; John, Esther M EM; Teixeira, Manuel R MR; Paulo, Paula P; Cardoso, Marta M; Neuhausen, Susan L SL; Steele, Linda L; Ding, Yuan Chun YC; De Ruyck, Kim K; De Meerleer, Gert G; Ost, Piet P; Razack, Azad A; Lim, Jasmine J; Teo, Soo-Hwang SH; Lin, Daniel W DW; Newcomb, Lisa F LF; Lessel, Davor D; Gamulin, Marija M; Kulis, Tomislav T; Kaneva, Radka R; Usmani, Nawaid N; Slavov, Chavdar C; Mitev, Vanio V; Parliament, Matthew M; Singhal, Sandeep S; Claessens, Frank F; Joniau, Steven S; Van den Broeck, Thomas T; Larkin, Samantha S; Townsend, Paul A PA; Aukim-Hastie, Claire C; Gago-Dominguez, Manuela M; Castelao, Jose Esteban JE; Martinez, Maria Elena ME; Roobol, Monique J MJ; Jenster, Guido G; van Schaik, Ron H N RHN; Menegaux, Florence F; Truong, Thérèse T; Koudou, Yves Akoli YA; Xu, Jianfeng J; Khaw, Kay-Tee KT; Cannon-Albright, Lisa L; Pandha, Hardev H; Michael, Agnieszka A; Kierzek, Andrzej A; Thibodeau, Stephen N SN; McDonnell, Shannon K SK; Schaid, Daniel J DJ; Lindstrom, Sara S; Turman, Constance C; Ma, Jing J; Hunter, David J DJ; Riboli, Elio E; Siddiq, Afshan A; Canzian, Federico F; Kolonel, Laurence N LN; Le Marchand, Loic L; Hoover, Robert N RN; Machiela, Mitchell J MJ; Kraft, Peter P; , ; Freedman, Matthew M; Wiklund, Fredrik F; Chanock, Stephen S; Henderson, Brian E BE; Easton, Douglas F DF; Haiman, Christopher A CA; Eeles, Rosalind A RA; Conti, David V DV; Kote-Jarai, Zsofia Z
Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.
Bmj (Clinical Research Ed.)
Seibert, Tyler M TM; Fan, Chun Chieh CC; Wang, Yunpeng Y; Zuber, Verena V; Karunamuni, Roshan R; Parsons, J Kellogg JK; Eeles, Rosalind A RA; Easton, Douglas F DF; Kote-Jarai, ZSofia Z; Al Olama, Ali Amin AA; Garcia, Sara Benlloch SB; Muir, Kenneth K; Grönberg, Henrik H; Wiklund, Fredrik F; Aly, Markus M; Schleutker, Johanna J; Sipeky, Csilla C; Tammela, Teuvo Lj TL; Nordestgaard, Børge G BG; Nielsen, Sune F SF; Weischer, Maren M; Bisbjerg, Rasmus R; Røder, M Andreas MA; Iversen, Peter P; Key, Tim J TJ; Travis, Ruth C RC; Neal, David E DE; Donovan, Jenny L JL; Hamdy, Freddie C FC; Pharoah, Paul P; Pashayan, Nora N; Khaw, Kay-Tee KT; Maier, Christiane C; Vogel, Walther W; Luedeke, Manuel M; Herkommer, Kathleen K; Kibel, Adam S AS; Cybulski, Cezary C; Wokolorczyk, Dominika D; Kluzniak, Wojciech W; Cannon-Albright, Lisa L; Brenner, Hermann H; Cuk, Katarina K; Saum, Kai-Uwe KU; Park, Jong Y JY; Sellers, Thomas A TA; Slavov, Chavdar C; Kaneva, Radka R; Mitev, Vanio V; Batra, Jyotsna J; Clements, Judith A JA; Spurdle, Amanda A; Teixeira, Manuel R MR; Paulo, Paula P; Maia, Sofia S; Pandha, Hardev H; Michael, Agnieszka A; Kierzek, Andrzej A; Karow, David S DS; Mills, Ian G IG; Andreassen, Ole A OA; Dale, Anders M AM; ,
Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21.
Human Genetics
Teerlink, Craig C CC; Leongamornlert, Daniel D; Dadaev, Tokhir T; Thomas, Alun A; Farnham, James J; Stephenson, Robert A RA; Riska, Shaun S; McDonnell, Shannon K SK; Schaid, Daniel J DJ; Catalona, William J WJ; Zheng, S Lilly SL; Cooney, Kathleen A KA; Ray, Anna M AM; Zuhlke, Kimberly A KA; Lange, Ethan M EM; Giles, Graham G GG; Southey, Melissa C MC; Fitzgerald, Liesel M LM; Rinckleb, Antje A; Luedeke, Manuel M; Maier, Christiane C; Stanford, Janet L JL; Ostrander, Elaine A EA; Kaikkonen, Elina M EM; Sipeky, Csilla C; Tammela, Teuvo T; Schleutker, Johanna J; Wiley, Kathleen E KE; Isaacs, Sarah D SD; Walsh, Patrick C PC; Isaacs, William B WB; Xu, Jianfeng J; Cancel-Tassin, Geraldine G; Cussenot, Olivier O; Mandal, Diptasri D; Laurie, Cecelia C; Laurie, Cathy C; , ; , ; Thibodeau, Stephen N SN; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z; Cannon-Albright, Lisa L
GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer.
Human Molecular Genetics
Chen, Maxine M MM; O'Mara, Tracy A TA; Thompson, Deborah J DJ; Painter, Jodie N JN; , ; Attia, John J; Black, Amanda A; Brinton, Louise L; Chanock, Stephen S; Chen, Chu C; Cheng, Timothy Ht TH; Cook, Linda S LS; Crous-Bou, Marta M; Doherty, Jennifer J; Friedenreich, Christine M CM; Garcia-Closas, Montserrat M; Gaudet, Mia M MM; Gorman, Maggie M; Haiman, Christopher C; Hankinson, Susan E SE; Hartge, Patricia P; Henderson, Brian E BE; Hodgson, Shirley S; Holliday, Elizabeth G EG; Horn-Ross, Pamela L PL; Hunter, David J DJ; Le Marchand, Loic L; Liang, Xiaolin X; Lissowska, Jolanta J; Long, Jirong J; Lu, Lingeng L; Magliocco, Anthony M AM; Martin, Lynn L; McEvoy, Mark M; , ; Olson, Sara H SH; Orlow, Irene I; Pooler, Loreall L; Prescott, Jennifer J; Rastogi, Radhai R; Rebbeck, Timothy R TR; Risch, Harvey H; Sacerdote, Carlotta C; Schumacher, Frederick F; Wendy Setiawan, Veronica V; Scott, Rodney J RJ; Sheng, Xin X; Shu, Xiao-Ou XO; Turman, Constance C; Van Den Berg, David D; Wang, Zhaoming Z; Weiss, Noel S NS; Wentzensen, Nicholas N; Xia, Lucy L; Xiang, Yong-Bing YB; Yang, Hannah P HP; Yu, Herbert H; Zheng, Wei W; Pharoah, Paul D P PD; Dunning, Alison M AM; Tomlinson, Ian I; Easton, Douglas F DF; Kraft, Peter P; Spurdle, Amanda B AB; De Vivo, Immaculata I
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Nature Genetics
Gaulton, Kyle J KJ; Ferreira, Teresa T; Lee, Yeji Y; Raimondo, Anne A; Mägi, Reedik R; Reschen, Michael E ME; Mahajan, Anubha A; Locke, Adam A; Rayner, N William NW; Robertson, Neil N; Scott, Robert A RA; Prokopenko, Inga I; Scott, Laura J LJ; Green, Todd T; Sparso, Thomas T; Thuillier, Dorothee D; Yengo, Loic L; Grallert, Harald H; Wahl, Simone S; Frånberg, Mattias M; Strawbridge, Rona J RJ; Kestler, Hans H; Chheda, Himanshu H; Eisele, Lewin L; Gustafsson, Stefan S; Steinthorsdottir, Valgerdur V; Thorleifsson, Gudmar G; Qi, Lu L; Karssen, Lennart C LC; van Leeuwen, Elisabeth M EM; Willems, Sara M SM; Li, Man M; Chen, Han H; Fuchsberger, Christian C; Kwan, Phoenix P; Ma, Clement C; Linderman, Michael M; Lu, Yingchang Y; Thomsen, Soren K SK; Rundle, Jana K JK; Beer, Nicola L NL; van de Bunt, Martijn M; Chalisey, Anil A; Kang, Hyun Min HM; Voight, Benjamin F BF; Abecasis, Gonçalo R GR; Almgren, Peter P; Baldassarre, Damiano D; Balkau, Beverley B; Benediktsson, Rafn R; Blüher, Matthias M; Boeing, Heiner H; Bonnycastle, Lori L LL; Bottinger, Erwin P EP; Burtt, Noël P NP; Carey, Jason J; Charpentier, Guillaume G; Chines, Peter S PS; Cornelis, Marilyn C MC; Couper, David J DJ; Crenshaw, Andrew T AT; van Dam, Rob M RM; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Eriksson, Johan G JG; Esko, Tonu T; Eury, Elodie E; Fadista, João J; Flannick, Jason J; Fontanillas, Pierre P; Fox, Caroline C; Franks, Paul W PW; Gertow, Karl K; Gieger, Christian C; Gigante, Bruna B; Gottesman, Omri O; Grant, George B GB; Grarup, Niels N; Groves, Christopher J CJ; Hassinen, Maija M; Have, Christian T CT; Herder, Christian C; Holmen, Oddgeir L OL; Hreidarsson, Astradur B AB; Humphries, Steve E SE; Hunter, David J DJ; Jackson, Anne U AU; Jonsson, Anna A; Jørgensen, Marit E ME; Jørgensen, Torben T; Kao, Wen-Hong L WH; Kerrison, Nicola D ND; Kinnunen, Leena L; Klopp, Norman N; Kong, Augustine A; Kovacs, Peter P; Kraft, Peter P; Kravic, Jasmina J; Langford, Cordelia C; Leander, Karin K; Liang, Liming L; Lichtner, Peter P; Lindgren, Cecilia M CM; Lindholm, Eero E; Linneberg, Allan A; Liu, Ching-Ti CT; Lobbens, Stéphane S; Luan, Jian'an J; Lyssenko, Valeriya V; Männistö, Satu S; McLeod, Olga O; Meyer, Julia J; Mihailov, Evelin E; Mirza, Ghazala G; Mühleisen, Thomas W TW; Müller-Nurasyid, Martina M; Navarro, Carmen C; Nöthen, Markus M MM; Oskolkov, Nikolay N NN; Owen, Katharine R KR; Palli, Domenico D; Pechlivanis, Sonali S; Peltonen, Leena L; Perry, John R B JR; Platou, Carl G P CG; Roden, Michael M; Ruderfer, Douglas D; Rybin, Denis D; van der Schouw, Yvonne T YT; Sennblad, Bengt B; Sigurðsson, Gunnar G; Stančáková, Alena A; Steinbach, Gerald G; Storm, Petter P; Strauch, Konstantin K; Stringham, Heather M HM; Sun, Qi Q; Thorand, Barbara B; Tikkanen, Emmi E; Tonjes, Anke A; Trakalo, Joseph J; Tremoli, Elena E; Tuomi, Tiinamaija T; Wennauer, Roman R; Wiltshire, Steven S; Wood, Andrew R AR; Zeggini, Eleftheria E; Dunham, Ian I; Birney, Ewan E; Pasquali, Lorenzo L; Ferrer, Jorge J; Loos, Ruth J F RJ; Dupuis, Josée J; Florez, Jose C JC; Boerwinkle, Eric E; Pankow, James S JS; van Duijn, Cornelia C; Sijbrands, Eric E; Meigs, James B JB; Hu, Frank B FB; Thorsteinsdottir, Unnur U; Stefansson, Kari K; Lakka, Timo A TA; Rauramaa, Rainer R; Stumvoll, Michael M; Pedersen, Nancy L NL; Lind, Lars L; Keinanen-Kiukaanniemi, Sirkka M SM; Korpi-Hyövälti, Eeva E; Saaristo, Timo E TE; Saltevo, Juha J; Kuusisto, Johanna J; Laakso, Markku M; Metspalu, Andres A; Erbel, Raimund R; Jöcke, Karl-Heinz KH; Moebus, Susanne S; Ripatti, Samuli S; Salomaa, Veikko V; Ingelsson, Erik E; Boehm, Bernhard O BO; Bergman, Richard N RN; Collins, Francis S FS; Mohlke, Karen L KL; Koistinen, Heikki H; Tuomilehto, Jaakko J; Hveem, Kristian K; Njølstad, Inger I; Deloukas, Panagiotis P; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; de Faire, Ulf U; Hamsten, Anders A; Illig, Thomas T; Peters, Annette A; Cauchi, Stephane S; Sladek, Rob R; Froguel, Philippe P; Hansen, Torben T; Pedersen, Oluf O; Morris, Andrew D AD; Palmer, Collin N A CN; Kathiresan, Sekar S; Melander, Olle O; Nilsson, Peter M PM; Groop, Leif C LC; Barroso, Inês I; Langenberg, Claudia C; Wareham, Nicholas J NJ; O'Callaghan, Christopher A CA; Gloyn, Anna L AL; Altshuler, David D; Boehnke, Michael M; Teslovich, Tanya M TM; McCarthy, Mark I MI; Morris, Andrew P AP; ,
Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis.
Journal Of The National Cancer Institute
Nead, Kevin T KT; Sharp, Stephen J SJ; Thompson, Deborah J DJ; Painter, Jodie N JN; Savage, David B DB; Semple, Robert K RK; Barker, Adam A; , ; Perry, John R B JR; Attia, John J; Dunning, Alison M AM; Easton, Douglas F DF; Holliday, Elizabeth E; Lotta, Luca A LA; O'Mara, Tracy T; McEvoy, Mark M; Pharoah, Paul D P PD; Scott, Rodney J RJ; Spurdle, Amanda B AB; Langenberg, Claudia C; Wareham, Nicholas J NJ; Scott, Robert A RA
A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.
Nature Communications
Ahmad, Omar S OS; Morris, John A JA; Mujammami, Muhammad M; Forgetta, Vincenzo V; Leong, Aaron A; Li, Rui R; Turgeon, Maxime M; Greenwood, Celia M T CM; Thanassoulis, George G; Meigs, James B JB; Sladek, Robert R; Richards, J Brent JB
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Human Molecular Genetics
Painter, Jodie N JN; O'Mara, Tracy A TA; Batra, Jyotsna J; Cheng, Timothy T; Lose, Felicity A FA; Dennis, Joe J; Michailidou, Kyriaki K; Tyrer, Jonathan P JP; Ahmed, Shahana S; Ferguson, Kaltin K; Healey, Catherine S CS; Kaufmann, Susanne S; Hillman, Kristine M KM; Walpole, Carina C; Moya, Leire L; Pollock, Pamela P; Jones, Angela A; Howarth, Kimberley K; Martin, Lynn L; Gorman, Maggie M; Hodgson, Shirley S; , ; , ; De Polanco, Ma Magdalena Echeverry MM; Sans, Monica M; Carracedo, Angel A; Castellvi-Bel, Sergi S; Rojas-Martinez, Augusto A; Santos, Erika E; Teixeira, Manuel R MR; Carvajal-Carmona, Luis L; Shu, Xiao-Ou XO; Long, Jirong J; Zheng, Wei W; Xiang, Yong-Bing YB; , ; Montgomery, Grant W GW; Webb, Penelope M PM; Scott, Rodney J RJ; McEvoy, Mark M; Attia, John J; Holliday, Elizabeth E; Martin, Nicholas G NG; Nyholt, Dale R DR; Henders, Anjali K AK; Fasching, Peter A PA; Hein, Alexander A; Beckmann, Matthias W MW; Renner, Stefan P SP; Dörk, Thilo T; Hillemanns, Peter P; Dürst, Matthias M; Runnebaum, Ingo I; Lambrechts, Diether D; Coenegrachts, Lieve L; Schrauwen, Stefanie S; Amant, Frederic F; Winterhoff, Boris B; Dowdy, Sean C SC; Goode, Ellen L EL; Teoman, Attila A; Salvesen, Helga B HB; Trovik, Jone J; Njolstad, Tormund S TS; Werner, Henrica M J HM; Ashton, Katie K; Proietto, Tony T; Otton, Geoffrey G; Tzortzatos, Gerasimos G; Mints, Miriam M; Tham, Emma E; , ; Hall, Per P; Czene, Kamila K; Liu, Jianjun J; Li, Jingmei J; Hopper, John L JL; Southey, Melissa C MC; , ; Ekici, Arif B AB; Ruebner, Matthias M; Johnson, Nicola N; Peto, Julian J; Burwinkel, Barbara B; Marme, Frederik F; Brenner, Hermann H; Dieffenbach, Aida K AK; Meindl, Alfons A; Brauch, Hiltrud H; , ; Lindblom, Annika A; Depreeuw, Jeroen J; Moisse, Matthieu M; Chang-Claude, Jenny J; Rudolph, Anja A; Couch, Fergus J FJ; Olson, Janet E JE; Giles, Graham G GG; Bruinsma, Fiona F; Cunningham, Julie M JM; Fridley, Brooke L BL; Børresen-Dale, Anne-Lise AL; Kristensen, Vessela N VN; Cox, Angela A; Swerdlow, Anthony J AJ; Orr, Nicholas N; Bolla, Manjeet K MK; Wang, Qin Q; Weber, Rachel Palmieri RP; Chen, Zhihua Z; Shah, Mitul M; French, Juliet D JD; Pharoah, Paul D P PD; Dunning, Alison M AM; Tomlinson, Ian I; Easton, Douglas F DF; Edwards, Stacey L SL; Thompson, Deborah J DJ; Spurdle, Amanda B AB
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study.
Plos Medicine
Langenberg, Claudia C; Sharp, Stephen J SJ; Franks, Paul W PW; Scott, Robert A RA; Deloukas, Panos P; Forouhi, Nita G NG; Froguel, Philippe P; Groop, Leif C LC; Hansen, Torben T; Palla, Luigi L; Pedersen, Oluf O; Schulze, Matthias B MB; Tormo, Maria-Jose MJ; Wheeler, Eleanor E; Agnoli, Claudia C; Arriola, Larraitz L; Barricarte, Aurelio A; Boeing, Heiner H; Clarke, Geraldine M GM; Clavel-Chapelon, Françoise F; Duell, Eric J EJ; Fagherazzi, Guy G; Kaaks, Rudolf R; Kerrison, Nicola D ND; Key, Timothy J TJ; Khaw, Kay Tee KT; Kröger, Janine J; Lajous, Martin M; Morris, Andrew P AP; Navarro, Carmen C; Nilsson, Peter M PM; Overvad, Kim K; Palli, Domenico D; Panico, Salvatore S; Quirós, J Ramón JR; Rolandsson, Olov O; Sacerdote, Carlotta C; Sánchez, María-José MJ; Slimani, Nadia N; Spijkerman, Annemieke M W AM; Tumino, Rosario R; van der A, Daphne L DL; van der Schouw, Yvonne T YT; Barroso, Inês I; McCarthy, Mark I MI; Riboli, Elio E; Wareham, Nicholas J NJ
Polygenic type 2 diabetes prediction at the limit of common variant detection.
Diabetes
Vassy, Jason L JL; Hivert, Marie-France MF; Porneala, Bianca B; Dauriz, Marco M; Florez, Jose C JC; Dupuis, Josée J; Siscovick, David S DS; Fornage, Myriam M; Rasmussen-Torvik, Laura J LJ; Bouchard, Claude C; Meigs, James B JB
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Nature Genetics
Morris, Andrew P AP; Voight, Benjamin F BF; Teslovich, Tanya M TM; Ferreira, Teresa T; Segrè, Ayellet V AV; Steinthorsdottir, Valgerdur V; Strawbridge, Rona J RJ; Khan, Hassan H; Grallert, Harald H; Mahajan, Anubha A; Prokopenko, Inga I; Kang, Hyun Min HM; Dina, Christian C; Esko, Tonu T; Fraser, Ross M RM; Kanoni, Stavroula S; Kumar, Ashish A; Lagou, Vasiliki V; Langenberg, Claudia C; Luan, Jian'an J; Lindgren, Cecilia M CM; Müller-Nurasyid, Martina M; Pechlivanis, Sonali S; Rayner, N William NW; Scott, Laura J LJ; Wiltshire, Steven S; Yengo, Loic L; Kinnunen, Leena L; Rossin, Elizabeth J EJ; Raychaudhuri, Soumya S; Johnson, Andrew D AD; Dimas, Antigone S AS; Loos, Ruth J F RJ; Vedantam, Sailaja S; Chen, Han H; Florez, Jose C JC; Fox, Caroline C; Liu, Ching-Ti CT; Rybin, Denis D; Couper, David J DJ; Kao, Wen Hong L WH; Li, Man M; Cornelis, Marilyn C MC; Kraft, Peter P; Sun, Qi Q; van Dam, Rob M RM; Stringham, Heather M HM; Chines, Peter S PS; Fischer, Krista K; Fontanillas, Pierre P; Holmen, Oddgeir L OL; Hunt, Sarah E SE; Jackson, Anne U AU; Kong, Augustine A; Lawrence, Robert R; Meyer, Julia J; Perry, John R B JR; Platou, Carl G P CG; Potter, Simon S; Rehnberg, Emil E; Robertson, Neil N; Sivapalaratnam, Suthesh S; Stančáková, Alena A; Stirrups, Kathleen K; Thorleifsson, Gudmar G; Tikkanen, Emmi E; Wood, Andrew R AR; Almgren, Peter P; Atalay, Mustafa M; Benediktsson, Rafn R; Bonnycastle, Lori L LL; Burtt, Noël N; Carey, Jason J; Charpentier, Guillaume G; Crenshaw, Andrew T AT; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Emilsson, Valur V; Eury, Elodie E; Forsen, Tom T; Gertow, Karl K; Gigante, Bruna B; Grant, George B GB; Groves, Christopher J CJ; Guiducci, Candace C; Herder, Christian C; Hreidarsson, Astradur B AB; Hui, Jennie J; James, Alan A; Jonsson, Anna A; Rathmann, Wolfgang W; Klopp, Norman N; Kravic, Jasmina J; Krjutškov, Kaarel K; Langford, Cordelia C; Leander, Karin K; Lindholm, Eero E; Lobbens, Stéphane S; Männistö, Satu S; Mirza, Ghazala G; Mühleisen, Thomas W TW; Musk, Bill B; Parkin, Melissa M; Rallidis, Loukianos L; Saramies, Jouko J; Sennblad, Bengt B; Shah, Sonia S; Sigurðsson, Gunnar G; Silveira, Angela A; Steinbach, Gerald G; Thorand, Barbara B; Trakalo, Joseph J; Veglia, Fabrizio F; Wennauer, Roman R; Winckler, Wendy W; Zabaneh, Delilah D; Campbell, Harry H; van Duijn, Cornelia C; Uitterlinden, Andre G AG; Hofman, Albert A; Sijbrands, Eric E; Abecasis, Goncalo R GR; Owen, Katharine R KR; Zeggini, Eleftheria E; Trip, Mieke D MD; Forouhi, Nita G NG; Syvänen, Ann-Christine AC; Eriksson, Johan G JG; Peltonen, Leena L; Nöthen, Markus M MM; Balkau, Beverley B; Palmer, Colin N A CN; Lyssenko, Valeriya V; Tuomi, Tiinamaija T; Isomaa, Bo B; Hunter, David J DJ; Qi, Lu L; , ; , ; , ; , ; , ; Shuldiner, Alan R AR; Roden, Michael M; Barroso, Ines I; Wilsgaard, Tom T; Beilby, John J; Hovingh, Kees K; Price, Jackie F JF; Wilson, James F JF; Rauramaa, Rainer R; Lakka, Timo A TA; Lind, Lars L; Dedoussis, George G; Njølstad, Inger I; Pedersen, Nancy L NL; Khaw, Kay-Tee KT; Wareham, Nicholas J NJ; Keinanen-Kiukaanniemi, Sirkka M SM; Saaristo, Timo E TE; Korpi-Hyövälti, Eeva E; Saltevo, Juha J; Laakso, Markku M; Kuusisto, Johanna J; Metspalu, Andres A; Collins, Francis S FS; Mohlke, Karen L KL; Bergman, Richard N RN; Tuomilehto, Jaakko J; Boehm, Bernhard O BO; Gieger, Christian C; Hveem, Kristian K; Cauchi, Stephane S; Froguel, Philippe P; Baldassarre, Damiano D; Tremoli, Elena E; Humphries, Steve E SE; Saleheen, Danish D; Danesh, John J; Ingelsson, Erik E; Ripatti, Samuli S; Salomaa, Veikko V; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S; Peters, Annette A; Illig, Thomas T; de Faire, Ulf U; Hamsten, Anders A; Morris, Andrew D AD; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; Boerwinkle, Eric E; Melander, Olle O; Kathiresan, Sekar S; Nilsson, Peter M PM; Deloukas, Panos P; Thorsteinsdottir, Unnur U; Groop, Leif C LC; Stefansson, Kari K; Hu, Frank F; Pankow, James S JS; Dupuis, Josée J; Meigs, James B JB; Altshuler, David D; Boehnke, Michael M; McCarthy, Mark I MI; ,