ERBB2 c.40_41delinsTA ;(p.A14Y)

Variant ID: 17-37856531-GC-TA

NM_004448.2(ERBB2):c.40_41delinsTA;(p.A14Y)

This variant was identified in 23 publications

View GRCh38 version.




Publications:


Increased expression of SYCP2 predicts poor prognosis in patients suffering from breast carcinoma.

Frontiers In Genetics
Zheng, Hongyan H; Guo, Xiaorong X; Li, Nan N; Qin, Luyao L; Li, Xiaoqing X; Lou, Ge G
Publication Date: 2022

Variant appearance in text: HER-2: A14Y
PubMed Link: 36159998
Variant Present in the following documents:
  • DataSheet7.xlsx, sheet 1
View BVdb publication page



ZNF703 promotes triple-negative breast cancer cells through cell-cycle signaling and associated with poor prognosis.

Bmc Cancer
Zhang, Xi X; Mu, Xin X; Huang, Ou O; Wang, Zhitang Z; Chen, Jialin J; Chen, Debo D; Wang, Gen G
Publication Date: 2022-03-02

Variant appearance in text: HER2: A14Y
PubMed Link: 35236318
Variant Present in the following documents:
  • 12885_2022_Article_9286.pdf
View BVdb publication page



An Efficient Algorithm for the Detection of Outliers in Mislabeled Omics Data.

Computational And Mathematical Methods In Medicine
Sun, Hongwei H; Wang, Jiu J; Zhang, Zhongwen Z; Hu, Naibao N; Wang, Tong T
Publication Date: 2021

Variant appearance in text: HER2: A14Y
PubMed Link: 34976114
Variant Present in the following documents:
  • Main text
  • CMMM2021-9436582.pdf
View BVdb publication page



AMPD1 Is Associated With the Immune Response and Serves as a Prognostic Marker in HER2-Positive Breast Cancer.

Frontiers In Oncology
Wang, Long L; Zhang, Xue X; Wang, Mengxue M; Li, Yunhai Y; Xu, Jiali J; Wei, Jiaying J; Li, Hongzhong H; Ren, Guosheng G; Yin, Xuedong X
Publication Date: 2021

Variant appearance in text: HER2: A14Y
PubMed Link: 34900696
Variant Present in the following documents:
  • Table_2.xlsx, sheet 3
View BVdb publication page



Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes.

Nature Communications
Lehmann, Brian D BD; Colaprico, Antonio A; Silva, Tiago C TC; Chen, Jianjiao J; An, Hanbing H; Ban, Yuguang Y; Huang, Hanchen H; Wang, Lily L; James, Jamaal L JL; Balko, Justin M JM; Gonzalez-Ericsson, Paula I PI; Sanders, Melinda E ME; Zhang, Bing B; Pietenpol, Jennifer A JA; Chen, X Steven XS
Publication Date: 2021-11-01

Variant appearance in text: HER2: A14Y
PubMed Link: 34725325
Variant Present in the following documents:
  • 41467_2021_26502_MOESM4_ESM.xlsx, sheet 2
View BVdb publication page



CXCL10 potentiates immune checkpoint blockade therapy in homologous recombination-deficient tumors.

Theranostics
Shi, Zhiwen Z; Shen, Jianfeng J; Qiu, Junjun J; Zhao, Qingguo Q; Hua, Keqin K; Wang, Hongyan H
Publication Date: 2021

Variant appearance in text: HER2: A14Y
PubMed Link: 34158843
Variant Present in the following documents:
  • thnov11p7175s1.xlsx, sheet 1
View BVdb publication page



Stage-specific protein-domain mutational profile of invasive ductal breast cancer.

Bmc Medical Genomics
Yu, Ting T; Choi, Kwok Pui KP; Chen, Ee Sin ES; Zhang, Louxin L
Publication Date: 2020-10-22

Variant appearance in text: HER2: A14Y
PubMed Link: 33087126
Variant Present in the following documents:
  • 12920_2020_777_MOESM8_ESM.xlsx, sheet 2
  • 12920_2020_777_MOESM3_ESM.xlsx, sheet 2
View BVdb publication page



High expression of MKK3 is associated with worse clinical outcomes in African American breast cancer patients.

Journal Of Translational Medicine
Yang, Xuan X; Amgad, Mohamed M; Cooper, Lee A D LAD; Du, Yuhong Y; Fu, Haian H; Ivanov, Andrey A AA
Publication Date: 2020-09-01

Variant appearance in text: HER2: A14Y
PubMed Link: 32873298
Variant Present in the following documents:
  • 12967_2020_2502_MOESM1_ESM.xlsx, sheet 8
View BVdb publication page



ClpP regulates breast cancer cell proliferation, invasion and apoptosis by modulating the Src/PI3K/Akt signaling pathway.

Peerj
Luo, Juan J; Zeng, Beilei B; Tao, Chunfang C; Lu, Mengqi M; Ren, Guosheng G
Publication Date: 2020

Variant appearance in text: HER2: A14Y
PubMed Link: 32195060
Variant Present in the following documents:
  • peerj-08-8754-s033.xlsx, sheet 1
View BVdb publication page



Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform.

Plos Biology
Blatti, Charles C; Emad, Amin A; Berry, Matthew J MJ; Gatzke, Lisa L; Epstein, Milt M; Lanier, Daniel D; Rizal, Pramod P; Ge, Jing J; Liao, Xiaoxia X; Sobh, Omar O; Lambert, Mike M; Post, Corey S CS; Xiao, Jinfeng J; Groves, Peter P; Epstein, Aidan T AT; Chen, Xi X; Srinivasan, Subhashini S; Lehnert, Erik E; Kalari, Krishna R KR; Wang, Liewei L; Weinshilboum, Richard M RM; Song, Jun S JS; Jongeneel, C Victor CV; Han, Jiawei J; Ravaioli, Umberto U; Sobh, Nahil N; Bushell, Colleen B CB; Sinha, Saurabh S
Publication Date: 2020-01

Variant appearance in text: ERBB2: A14Y
PubMed Link: 31971940
Variant Present in the following documents:
  • pbio.3000583.s006.xlsx, sheet 13
View BVdb publication page



NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers.

Molecular Oncology
Bertucci, François F; Rypens, Charlotte C; Finetti, Pascal P; Guille, Arnaud A; Adélaïde, José J; Monneur, Audrey A; Carbuccia, Nadine N; Garnier, Séverine S; Dirix, Piet P; Gonçalves, Anthony A; Vermeulen, Peter P; Debeb, Bisrat G BG; Wang, Xiaoping X; Dirix, Luc L; Ueno, Naoto T NT; Viens, Patrice P; Cristofanilli, Massimo M; Chaffanet, Max M; Birnbaum, Daniel D; Van Laere, Steven S
Publication Date: 2020-03

Variant appearance in text: ERBB2: A14Y
PubMed Link: 31854063
Variant Present in the following documents:
  • MOL2-14-504-s010.xlsx, sheet 1
View BVdb publication page



Exploring the Pathological Mechanism of Bladder Cancer Based on Tumor Mutational Burden Analysis.

Biomed Research International
Ma, Yao Y; Feng, Xiao-Fei XF; Yang, Wan-Xia WX; You, Chong-Ge CG
Publication Date: 2019

Variant appearance in text: ERBB2: A14Y
PubMed Link: 31534952
Variant Present in the following documents:
  • BMRI2019-1093815.pdf
View BVdb publication page



Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling.

Nature Communications
Robinson, Brian D BD; Vlachostergios, Panagiotis J PJ; Bhinder, Bhavneet B; Liu, Weisi W; Li, Kailyn K; Moss, Tyler J TJ; Bareja, Rohan R; Park, Kyung K; Tavassoli, Peyman P; Cyrta, Joanna J; Tagawa, Scott T ST; Nanus, David M DM; Beltran, Himisha H; Molina, Ana M AM; Khani, Francesca F; Miguel Mosquera, Juan J; Xylinas, Evanguelos E; Shariat, Shahrokh F SF; Scherr, Douglas S DS; Rubin, Mark A MA; Lerner, Seth P SP; Matin, Surena F SF; Elemento, Olivier O; Faltas, Bishoy M BM
Publication Date: 2019-07-05

Variant appearance in text: ERBB2: A14Y
PubMed Link: 31278255
Variant Present in the following documents:
  • 41467_2019_10873_MOESM3_ESM.xlsx, sheet 18
View BVdb publication page



Robust identification of target genes and outliers in triple-negative breast cancer data.

Statistical Methods In Medical Research
Segaert, Pieter P; Lopes, Marta B MB; Casimiro, Sandra S; Vinga, Susana S; Rousseeuw, Peter J PJ
Publication Date: 2019

Variant appearance in text: HER2: A14Y
PubMed Link: 30146936
Variant Present in the following documents:
  • Main text
  • 10.1177_0962280218794722.pdf
View BVdb publication page



Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine
Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L
Publication Date: 2018-07-27

Variant appearance in text: HER-2: A14Y
PubMed Link: 30053901
Variant Present in the following documents:
  • 13073_2018_564_MOESM2_ESM.xlsx, sheet 10
View BVdb publication page



Pathway-based dissection of the genomic heterogeneity of cancer hallmarks' acquisition with SLAPenrich.

Scientific Reports
Iorio, Francesco F; Garcia-Alonso, Luz L; Brammeld, Jonathan S JS; Martincorena, Iňigo I; Wille, David R DR; McDermott, Ultan U; Saez-Rodriguez, Julio J
Publication Date: 2018-04-30

Variant appearance in text: ERBB2: A14Y
PubMed Link: 29713020
Variant Present in the following documents:
  • 41598_2018_25076_MOESM8_ESM.xlsx, sheet 1
View BVdb publication page



Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma.

Scientific Reports
Bjørklund, Sunniva Stordal SS; Panda, Anshuman A; Kumar, Surendra S; Seiler, Michael M; Robinson, Doug D; Gheeya, Jinesh J; Yao, Ming M; Alnæs, Grethe I Grenaker GIG; Toppmeyer, Deborah D; Riis, Margit M; Naume, Bjørn B; Børresen-Dale, Anne-Lise AL; Kristensen, Vessela N VN; Ganesan, Shridar S; Bhanot, Gyan G
Publication Date: 2017-07-17

Variant appearance in text: HER2: A14Y
PubMed Link: 28717182
Variant Present in the following documents:
  • 41598_2017_5537_MOESM1_ESM.pdf
View BVdb publication page



Her2 alterations in muscle-invasive bladder cancer: Patient selection beyond protein expression for targeted therapy.

Scientific Reports
Kiss, Bernhard B; Wyatt, Alexander W AW; Douglas, James J; Skuginna, Veronika V; Mo, Fan F; Anderson, Shawn S; Rotzer, Diana D; Fleischmann, Achim A; Genitsch, Vera V; Hayashi, Tetsutaro T; Neuenschwander, Maja M; Buerki, Christine C; Davicioni, Elai E; Collins, Colin C; Thalmann, George N GN; Black, Peter C PC; Seiler, Roland R
Publication Date: 2017-02-16

Variant appearance in text: ERBB2: A14Y
PubMed Link: 28205537
Variant Present in the following documents:
View BVdb publication page



Expression of human endogenous retrovirus-K is strongly associated with the basal-like breast cancer phenotype.

Scientific Reports
Johanning, Gary L GL; Malouf, Gabriel G GG; Zheng, Xiaofeng X; Esteva, Francisco J FJ; Weinstein, John N JN; Wang-Johanning, Feng F; Su, Xiaoping X
Publication Date: 2017-02-06

Variant appearance in text: HER2: A14Y
PubMed Link: 28165048
Variant Present in the following documents:
  • srep41960-s2.xls, sheet 1
  • srep41960-s1.xls, sheet 1
View BVdb publication page



Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer.

Bmc Genomics
Jiang, Guanglong G; Zhang, Shijun S; Yazdanparast, Aida A; Li, Meng M; Pawar, Aniruddha Vikram AV; Liu, Yunlong Y; Inavolu, Sai Mounika SM; Cheng, Lijun L
Publication Date: 2016-08-22

Variant appearance in text: HER2: A14Y
PubMed Link: 27556158
Variant Present in the following documents:
  • 12864_2016_2911_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Transcriptome sequencing uncovers a three-long noncoding RNA signature in predicting breast cancer survival.

Scientific Reports
Guo, Wenna W; Wang, Qiang Q; Zhan, Yueping Y; Chen, Xijia X; Yu, Qi Q; Zhang, Jiawei J; Wang, Yi Y; Xu, Xin-Jian XJ; Zhu, Liucun L
Publication Date: 2016-06-24

Variant appearance in text: HER2: A14Y
PubMed Link: 27338266
Variant Present in the following documents:
  • srep27931-s1.pdf
View BVdb publication page



Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection.

Plos One
Lehmann, Brian D BD; Jovanović, Bojana B; Chen, Xi X; Estrada, Monica V MV; Johnson, Kimberly N KN; Shyr, Yu Y; Moses, Harold L HL; Sanders, Melinda E ME; Pietenpol, Jennifer A JA
Publication Date: 2016

Variant appearance in text: HER2: A14Y
PubMed Link: 27310713
Variant Present in the following documents:
  • pone.0157368.s008.xlsx, sheet 2
View BVdb publication page



Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value.

Bmc Cancer
Lehmann, Brian David BD; Ding, Yan Y; Viox, Daniel Joseph DJ; Jiang, Ming M; Zheng, Yi Y; Liao, Wang W; Chen, Xi X; Xiang, Wei W; Yi, Yajun Y
Publication Date: 2015-03-26

Variant appearance in text: HER2: A14Y
PubMed Link: 25886164
Variant Present in the following documents:
  • 12885_2015_1102_MOESM1_ESM.pdf
View BVdb publication page