Design and characterization of homogenous antibody-drug conjugates with a drug-to-antibody ratio of one prepared using an engineered antibody and a dual-maleimide pyrrolobenzodiazepine dimer.
Mabs
White, Jason B JB; Fleming, Ryan R; Masterson, Luke L; Ruddle, Ben T BT; Zhong, Haihong H; Fazenbaker, Christine C; Strout, Patrick P; Rosenthal, Kim K; Reed, Molly M; Muniz-Medina, Vanessa V; Howard, Philip P; Dixit, Rakesh R; Wu, Herren H; Hinrichs, Mary Jane MJ; Gao, Changshou C; Dimasi, Nazzareno N