Publications:

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Synchronous intracellular delivery of EGFR-targeted antibody-drug conjugates by p38-mediated non-canonical endocytosis.

Scientific Reports

Takahashi, Jun-Ichiro JI; Nakamura, Shiori S; Onuma, Iimi I; Zhou, Yue Y; Yokoyama, Satoru S; Sakurai, Hiroaki H

Publication Date: 2022-07-07

Variant appearance in text: HER2: I682Q

PubMed Link: 35798841

Variant Present in the following documents:

• Main text
• 41598_2022_Article_15838.pdf

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Structure-function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting.

Nature Communications

Du, Zhenfang Z; Brown, Benjamin P BP; Kim, Soyeon S; Ferguson, Donna D; Pavlick, Dean C DC; Jayakumaran, Gowtham G; Benayed, Ryma R; Gallant, Jean-Nicolas JN; Zhang, Yun-Kai YK; Yan, Yingjun Y; Red-Brewer, Monica M; Ali, Siraj M SM; Schrock, Alexa B AB; Zehir, Ahmet A; Ladanyi, Marc M; Smith, Adam W AW; Meiler, Jens J; Lovly, Christine M CM

Publication Date: 2021-03-02

Variant appearance in text: HER2: I682Q

PubMed Link: 33654076

Variant Present in the following documents:

• 41467_2021_21613_MOESM2_ESM.pdf

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A Brief History of Single-Particle Tracking of the Epidermal Growth Factor Receptor.

Methods And Protocols

Clarke, David T DT; Martin-Fernandez, Marisa L ML

Publication Date: 2019-01-30

Variant appearance in text: HER2: I682Q

PubMed Link: 31164594

Variant Present in the following documents:

• Main text

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Structure and Dynamics of the EGF Receptor as Revealed by Experiments and Simulations and Its Relevance to Non-Small Cell Lung Cancer.

Cells

Martin-Fernandez, Marisa L ML; Clarke, David T DT; Roberts, Selene K SK; Zanetti-Domingues, Laura C LC; Gervasio, Francesco L FL

Publication Date: 2019-04-05

Variant appearance in text: HER2: I682Q

PubMed Link: 30959819

Variant Present in the following documents:

• cells-08-00316.pdf

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The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers.

Nature Communications

Zanetti-Domingues, Laura C LC; Korovesis, Dimitrios D; Needham, Sarah R SR; Tynan, Christopher J CJ; Sagawa, Shiori S; Roberts, Selene K SK; Kuzmanic, Antonija A; Ortiz-Zapater, Elena E; Jain, Purvi P; Roovers, Rob C RC; Lajevardipour, Alireza A; van Bergen En Henegouwen, Paul M P PMP; Santis, George G; Clayton, Andrew H A AHA; Clarke, David T DT; Gervasio, Francesco L FL; Shan, Yibing Y; Shaw, David E DE; Rolfe, Daniel J DJ; Parker, Peter J PJ; Martin-Fernandez, Marisa L ML

Publication Date: 2018-10-18

Variant appearance in text: HER2: I682Q

PubMed Link: 30337523

Variant Present in the following documents:

• Main text
• 41467_2018_Article_6632.pdf

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Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23.

Structure (London, England : 1993)

Liu, Lijun L; Thaker, Tarjani M TM; Freed, Daniel M DM; Frazier, Nicole N; Malhotra, Ketan K; Lemmon, Mark A MA; Jura, Natalia N

Publication Date: 2018-02-06

Variant appearance in text: HER2: I682Q

PubMed Link: 29358026

Variant Present in the following documents:

• Main text

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Molecular basis for multimerization in the activation of the epidermal growth factor receptor.

Elife

Huang, Yongjian Y; Bharill, Shashank S; Karandur, Deepti D; Peterson, Sean M SM; Marita, Morgan M; Shi, Xiaojun X; Kaliszewski, Megan J MJ; Smith, Adam W AW; Isacoff, Ehud Y EY; Kuriyan, John J

Publication Date: 2016-03-28

Variant appearance in text: HER2: I682Q

PubMed Link: 27017828

Variant Present in the following documents:

• Main text
• elife-14107.pdf

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Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor.

Molecular And Cellular Biology

Kovacs, Erika E; Das, Rahul R; Wang, Qi Q; Collier, Timothy S TS; Cantor, Aaron A; Huang, Yongjian Y; Wong, Kathryn K; Mirza, Amar A; Barros, Tiago T; Grob, Patricia P; Jura, Natalia N; Bose, Ron R; Kuriyan, John J

Publication Date: 2015-09-01

Variant appearance in text: HER2: I682Q

PubMed Link: 26124280

Variant Present in the following documents:

• Main text

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A structural perspective on the regulation of the epidermal growth factor receptor.

Annual Review Of Biochemistry

Kovacs, Erika E; Zorn, Julie Anne JA; Huang, Yongjian Y; Barros, Tiago T; Kuriyan, John J

Publication Date: 2015

Variant appearance in text: HER2: I682Q

PubMed Link: 25621509

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Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations.

Science Signaling

Littlefield, Peter P; Liu, Lijun L; Mysore, Venkatesh V; Shan, Yibing Y; Shaw, David E DE; Jura, Natalia N

Publication Date: 2014-12-02

Variant appearance in text: HER2: I682Q

PubMed Link: 25468994

Variant Present in the following documents:

• Main text

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Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Jura, Natalia N; Shan, Yibing Y; Cao, Xiaoxian X; Shaw, David E DE; Kuriyan, John J

Publication Date: 2009-12-22

Variant appearance in text: HER2: I682Q

PubMed Link: 20007378

Variant Present in the following documents:

• Main text

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Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.

Nature

Zhang, Xuewu X; Pickin, Kerry A KA; Bose, Ron R; Jura, Natalia N; Cole, Philip A PA; Kuriyan, John J

Publication Date: 2007-11-29

Variant appearance in text: ERBB2: I682Q

PubMed Link: 18046415

Variant Present in the following documents:

• Main text

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