ERBB2 c.2132A>T ;(p.Q711L)

Variant ID: 17-37879837-A-T

NM_004448.2(ERBB2):c.2132A>T;(p.Q711L)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


A small molecule inhibitor of HER3: a proof-of-concept study.

The Biochemical Journal
Colomba, Audrey A; Fitzek, Martina M; George, Roger R; Weitsman, Gregory G; Roberts, Selene S; Zanetti-Domingues, Laura L; Hirsch, Michael M; Rolfe, Daniel J DJ; Mehmood, Shahid S; Madin, Andrew A; Claus, Jeroen J; Kjaer, Svend S; Snijders, Ambrosius P AP; Ng, Tony T; Martin-Fernandez, Marisa M; Smith, David M DM; Parker, Peter J PJ
Publication Date: 2020-09-18

Variant appearance in text: HER2: Q711L
PubMed Link: 32815546
Variant Present in the following documents:
  • Main text
  • BCJ-477-3329.pdf
View BVdb publication page



Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 protein.

The Journal Of Biological Chemistry
Aertgeerts, Kathleen K; Skene, Robert R; Yano, Jason J; Sang, Bi-Ching BC; Zou, Hua H; Snell, Gyorgy G; Jennings, Andy A; Iwamoto, Keiji K; Habuka, Noriyuki N; Hirokawa, Aki A; Ishikawa, Tomoyasu T; Tanaka, Toshimasa T; Miki, Hiroshi H; Ohta, Yoshikazu Y; Sogabe, Satoshi S
Publication Date: 2011-05-27

Variant appearance in text: HER2: Q711L
PubMed Link: 21454582
Variant Present in the following documents:
  • Main text
View BVdb publication page