Publications:

Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.

Cell Reports

Campbell, Marcia R MR; Ruiz-Saenz, Ana A; Peterson, Elliott E; Agnew, Christopher C; Ayaz, Pelin P; Garfinkle, Sam S; Littlefield, Peter P; Steri, Veronica V; Oeffinger, Julie J; Sampang, Maryjo M; Shan, Yibing Y; Shaw, David E DE; Jura, Natalia N; Moasser, Mark M MM

Publication Date: 2022-02-01

Variant appearance in text: HER2: I714Q

PubMed Link: 35108525

Variant Present in the following documents:

• nihms-1776708.pdf

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Single-molecule functional anatomy of endogenous HER2-HER3 heterodimers.

Elife

Choi, Byoungsan B; Cha, Minkwon M; Eun, Gee Sung GS; Lee, Dae Hee DH; Lee, Seul S; Ehsan, Muhammad M; Chae, Pil Seok PS; Heo, Won Do WD; Park, YongKeun Y; Yoon, Tae-Young TY

Publication Date: 2020-04-08

Variant appearance in text: HER2: I714Q

PubMed Link: 32267234

Variant Present in the following documents:

• Main text
• elife-53934.pdf

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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations.

Cancer Cell

Pahuja, Kanika Bajaj KB; Nguyen, Thong T TT; Jaiswal, Bijay S BS; Prabhash, Kumar K; Thaker, Tarjani M TM; Senger, Kate K; Chaudhuri, Subhra S; Kljavin, Noelyn M NM; Antony, Aju A; Phalke, Sameer S; Kumar, Prasanna P; Mravic, Marco M; Stawiski, Eric W EW; Vargas, Derek D; Durinck, Steffen S; Gupta, Ravi R; Khanna-Gupta, Arati A; Trabucco, Sally E SE; Sokol, Ethan S ES; Hartmaier, Ryan J RJ; Singh, Ashish A; Chougule, Anuradha A; Trivedi, Vaishakhi V; Dutt, Amit A; Patil, Vijay V; Joshi, Amit A; Noronha, Vanita V; Ziai, James J; Banavali, Sripad D SD; Ramprasad, Vedam V; DeGrado, William F WF; Bueno, Raphael R; Jura, Natalia N; Seshagiri, Somasekar S

Publication Date: 2018-11-12

Variant appearance in text: HER2: I714Q

PubMed Link: 30449325

Variant Present in the following documents:

• Main text

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Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface.

Elife

Claus, Jeroen J; Patel, Gargi G; Autore, Flavia F; Colomba, Audrey A; Weitsman, Gregory G; Soliman, Tanya N TN; Roberts, Selene S; Zanetti-Domingues, Laura C LC; Hirsch, Michael M; Collu, Francesca F; George, Roger R; Ortiz-Zapater, Elena E; Barber, Paul R PR; Vojnovic, Boris B; Yarden, Yosef Y; Martin-Fernandez, Marisa L ML; Cameron, Angus A; Fraternali, Franca F; Ng, Tony T; Parker, Peter J PJ

Publication Date: 2018-05-01

Variant appearance in text: HER2: I714Q

PubMed Link: 29712619

Variant Present in the following documents:

• Main text
• elife-32271.pdf

View BVdb publication page