ERBB2 c.2258A>T ;(p.K753I)

Variant ID: 17-37880214-A-T

NM_004448.2(ERBB2):c.2258A>T;(p.K753I)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies.

Frontiers In Oncology
Bergado-Báez, Gretchen G; Gonzalez Suarez, Narjara N; García, Lisset Chao LC; Pérez-Martínez, Dayana D; Hernández-Fernández, Diana Rosa DR; Fundora-Barrios, Talia T; Rodríguez-Álvarez, Antonio A; Díaz-Ordaz, Geidy Diana GD; Lindzen, Moshit M; Yarden, Yosef Y; Sánchez-Ramírez, Belinda B
Publication Date: 2022

Variant appearance in text: HER2: K753I
PubMed Link: 36408164
Variant Present in the following documents:
  • Main text
  • fonc-12-951267.pdf
View BVdb publication page



Case Report: Effective Treatment With Pyrotinib and Capecitabine in a Heavily Pretreated Locally Advanced Breast Cancer Harboring Both HER2 Overexpression and Mutant.

Frontiers In Oncology
Gao, Zhichao Z; Xu, Junnan J; Wang, Yan Y; Wu, Jie J; Sun, Tao T
Publication Date: 2021

Variant appearance in text: HER2: K753I
PubMed Link: 34722261
Variant Present in the following documents:
  • Main text
  • fonc-11-715554.pdf
View BVdb publication page



Somatic Mutations in HER2 and Implications for Current Treatment Paradigms in HER2-Positive Breast Cancer.

Journal Of Oncology
Gaibar, Maria M; Beltrán, Laura L; Romero-Lorca, Alicia A; Fernández-Santander, Ana A; Novillo, Apolonia A
Publication Date: 2020

Variant appearance in text: HER2: K753I
PubMed Link: 32256585
Variant Present in the following documents:
  • Main text
  • JO2020-6375956.pdf
View BVdb publication page