ERBB2 c.2278T>G ;(p.S760A)

Variant ID: 17-37880234-T-G

NM_004448.2(ERBB2):c.2278T>G;(p.S760A)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets.

Breast Cancer Research : Bcr
Kurozumi, Sasagu S; Alsaleem, Mansour M; Monteiro, CĂ­ntia J CJ; Bhardwaj, Kartikeya K; Joosten, Stacey E P SEP; Fujii, Takaaki T; Shirabe, Ken K; Green, Andrew R AR; Ellis, Ian O IO; Rakha, Emad A EA; Mongan, Nigel P NP; Heery, David M DM; Zwart, Wilbert W; Oesterreich, Steffi S; Johnston, Simon J SJ
Publication Date: 2020-08-11

Variant appearance in text: HER2: S760A
PubMed Link: 32782013
Variant Present in the following documents:
  • Main text
  • 13058_2020_Article_1324.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: ERBB2: S760A
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
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Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls
Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R
Publication Date: 2019-07

Variant appearance in text: HER2: S760A
PubMed Link: 30982079
Variant Present in the following documents:
  • Main text
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: ERBB2: S760A
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Activating HER2 mutations in HER2 gene amplification negative breast cancer.

Cancer Discovery
Bose, Ron R; Kavuri, Shyam M SM; Searleman, Adam C AC; Shen, Wei W; Shen, Dong D; Koboldt, Daniel C DC; Monsey, John J; Goel, Nicholas N; Aronson, Adam B AB; Li, Shunqiang S; Ma, Cynthia X CX; Ding, Li L; Mardis, Elaine R ER; Ellis, Matthew J MJ
Publication Date: 2013-02

Variant appearance in text: HER2: S760A
PubMed Link: 23220880
Variant Present in the following documents:
  • Main text
View BVdb publication page