Publications:

The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.

Biomolecules

Shin, Jung Won JW; Kim, Soohyun S; Ha, Suji S; Choi, Byungsan B; Kim, Seongyeong S; Im, Seock-Ah SA; Yoon, Tae-Young TY; Chung, Junho J

Publication Date: 2019-10-19

Variant appearance in text: HER2: G776R

PubMed Link: 31635022

Variant Present in the following documents:

• Main text
• biomolecules-09-00629.pdf

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Clinical sequencing using a next-generation sequencing-based multiplex gene assay in patients with advanced solid tumors.

Cancer Science

Kou, Tadayuki T; Kanai, Masashi M; Yamamoto, Yoshihiro Y; Kamada, Mayumi M; Nakatsui, Masahiko M; Sakuma, Tomohiro T; Mochizuki, Hiroaki H; Hiroshima, Akinori A; Sugiyama, Aiko A; Nakamura, Eijiro E; Miyake, Hidehiko H; Minamiguchi, Sachiko S; Takaori, Kyoichi K; Matsumoto, Shigemi S; Haga, Hironori H; Seno, Hiroshi H; Kosugi, Shinji S; Okuno, Yasushi Y; Muto, Manabu M

Publication Date: 2017-07

Variant appearance in text: ERBB2: Gly776Arg

PubMed Link: 28440963

Variant Present in the following documents:

• Main text
• CAS-108-1440.pdf

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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research

Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U

Publication Date: 2017-04

Variant appearance in text: ERBB2: 2326G>C

PubMed Link: 28179366

Variant Present in the following documents:

• supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1

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HER2 somatic mutations are associated with poor survival in HER2-negative breast cancers.

Cancer Science

Wang, Tonghui T; Xu, Ye Y; Sheng, Shuyan S; Yuan, Hua H; Ouyang, Tao T; Li, Jinfeng J; Wang, Tianfeng T; Fan, Zhaoqing Z; Fan, Tie T; Lin, Benyao B; Xie, Yuntao Y

Publication Date: 2017-04

Variant appearance in text: HER2: G776R

PubMed Link: 28164408

Variant Present in the following documents:

• Main text
• CAS-108-671.pdf

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