Publications:

---

Unlocking the Resistance to Anti-HER2 Treatments in Breast Cancer: The Issue of HER2 Spatial Distribution.

Cancers

Giugliano, Federica F; Carnevale Schianca, Ambra A; Corti, Chiara C; Ivanova, Mariia M; Bianco, Nadia N; Dellapasqua, Silvia S; Criscitiello, Carmen C; Fusco, Nicola N; Curigliano, Giuseppe G; Munzone, Elisabetta E

Publication Date: 2023-02-22

Variant appearance in text: HER2: T798I

PubMed Link: 36900178

Variant Present in the following documents:

• cancers-15-01385.pdf

View BVdb publication page

---

Improving HER2 testing reproducibility in HER2-low breast cancer.

Cancer Drug Resistance (Alhambra, Calif.)

Sajjadi, Elham E; Venetis, Konstantinos K; Ivanova, Mariia M; Fusco, Nicola N

Publication Date: 2022

Variant appearance in text: HER2: T798I

PubMed Link: 36627898

Variant Present in the following documents:

• cdr-5-4-882.pdf

View BVdb publication page

---

The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: ERBB2: T798I

PubMed Link: 36222846

Variant Present in the following documents:

• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
• ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1

View BVdb publication page

---

Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021.

Journal Of Hematology & Oncology

Wu, Qing Q; Qian, Wei W; Sun, Xiaoli X; Jiang, Shaojie S

Publication Date: 2022-10-08

Variant appearance in text: HER2: T798I

PubMed Link: 36209184

Variant Present in the following documents:

• Main text
• 13045_2022_Article_1362.pdf

View BVdb publication page

---

AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery

Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,

Publication Date: 2022-09-02

Variant appearance in text: ERBB2: T798I

PubMed Link: 35819403

Variant Present in the following documents:

• cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1

View BVdb publication page

---

Understanding the activating mechanism of the immune system against COVID-19 by Traditional Indian Medicine: Network pharmacology approach.

Advances In Protein Chemistry And Structural Biology

Thirumal Kumar, D D; Shree Devi, M S MS; Udhaya Kumar, S S; Sherlin, Annie A; Mathew, Aishwarya A; Lakshmipriya, M M; Sathiyarajeswaran, P P; Gnanasambandan, R R; Siva, R R; Magesh, R R; George Priya Doss, C C

Publication Date: 2022

Variant appearance in text: ERBB2: T798I

PubMed Link: 35305722

Variant Present in the following documents:

• mmc09-01-9780323992275.pdf

View BVdb publication page

---

Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: ERBB2: T798I

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

View BVdb publication page

---

The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: ERBB2: Thr798Ile

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

---

Understanding Drug Sensitivity and Tackling Resistance in Cancer.

Cancer Research

Tyner, Jeffrey W JW; Haderk, Franziska F; Kumaraswamy, Anbarasu A; Baughn, Linda B LB; Van Ness, Brian B; Liu, Song S; Marathe, Himangi H; Alumkal, Joshi J JJ; Bivona, Trever G TG; Chan, Keith Syson KS; Druker, Brian J BJ; Hutson, Alan D AD; Nelson, Peter S PS; Sawyers, Charles L CL; Willey, Christopher D CD

Publication Date: 2022-04-15

Variant appearance in text: HER2: T798I

PubMed Link: 35195258

Variant Present in the following documents:

• 1448.pdf

View BVdb publication page

---

Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib.

Npj Breast Cancer

Shishido, Stephanie N SN; Masson, Rahul R; Xu, Liya L; Welter, Lisa L; Prabakar, Rishvanth Kaliappan RK; D' Souza, Anishka A; Spicer, Darcy D; Kang, Irene I; Jayachandran, Priya P; Hicks, James J; Lu, Janice J; Kuhn, Peter P

Publication Date: 2022-02-18

Variant appearance in text: HER2: T798I

PubMed Link: 35181666

Variant Present in the following documents:

• Main text
• 41523_2022_Article_390.pdf

View BVdb publication page

---

Role of ctDNA in Breast Cancer.

Cancers

Sant, Marta M; Bernat-Peguera, Adrià A; Felip, Eudald E; Margelí, Mireia M

Publication Date: 2022-01-09

Variant appearance in text: HER2: T798I

PubMed Link: 35053474

Variant Present in the following documents:

• Main text
• cancers-14-00310.pdf

View BVdb publication page

---

Role of ctDNA in Breast Cancer.

Cancers

Sant, Marta M; Bernat-Peguera, Adrià A; Felip, Eudald E; Margelí, Mireia M

Publication Date: 2022-01-09

Variant appearance in text: HER2: T798I

PubMed Link: 35053474

Variant Present in the following documents:

• Main text
• cancers-14-00310.pdf

View BVdb publication page

---

Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis.

Cell Death Discovery

Liao, Min M; Dong, Qiongye Q; Chen, Ruiqing R; Xu, Liqian L; Jiang, Yuxuan Y; Guo, Zhenxing Z; Xiao, Min M; He, Wei W; Cao, Changcai C; Hu, Ronghua R; Sun, Wanling W; Jiang, Hong H; Wang, Jianwei J

Publication Date: 2021-10-18

Variant appearance in text: ERBB2: T798I

PubMed Link: 34663800

Variant Present in the following documents:

• 41420_2021_697_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

Mutant HER2 needs mutant HER3 to be an effective oncogene.

Cell Reports. Medicine

Trenker, Raphael R; Diwanji, Devan D; Jura, Natalia N

Publication Date: 2021-08-17

Variant appearance in text: HER2: T798I

PubMed Link: 34467245

Variant Present in the following documents:

• main.pdf

View BVdb publication page

---

Clinical genomic profiling to identify actionable alterations for very early relapsed triple-negative breast cancer patients in the Chinese population.

Annals Of Medicine

Wang, Liye L; Zhai, Qinglian Q; Lu, Qianyi Q; Lee, Kaping K; Zheng, Qiufan Q; Hong, Ruoxi R; Wang, Shusen S

Publication Date: 2021-12

Variant appearance in text: ERBB2: T798I

PubMed Link: 34396843

Variant Present in the following documents:

• Main text

View BVdb publication page

---

miR-221 confers lapatinib resistance by negatively regulating p27kip1 in HER2-positive breast cancer.

Cancer Science

Huynh, Thanh Kieu TK; Huang, Chih-Hao CH; Chen, Jhen-Yu JY; Yao, Jin-Han JH; Yang, Yi-Shiang YS; Wei, Ya-Ling YL; Chen, Hsiao-Fan HF; Chen, Chia-Hung CH; Tu, Chih-Yen CY; Hsu, Yuan-Man YM; Liu, Liang-Chih LC; Huang, Wei-Chien WC

Publication Date: 2021-10

Variant appearance in text: HER2: T798I

PubMed Link: 34382727

Variant Present in the following documents:

• Main text
• CAS-112-4234.pdf

View BVdb publication page

---

Pim1 Kinase Inhibitors Exert Anti-Cancer Activity Against HER2-Positive Breast Cancer Cells Through Downregulation of HER2.

Frontiers In Pharmacology

Wang, Bo-Wei BW; Huang, Chih-Hao CH; Liu, Liang-Chih LC; Cheng, Fang-Ju FJ; Wei, Ya-Ling YL; Lin, Yueh-Ming YM; Wang, Yu-Fei YF; Wei, Ching-Ting CT; Chen, Yeh Y; Chen, Yun-Ju YJ; Huang, Wei-Chien WC

Publication Date: 2021

Variant appearance in text: HER2: T798I

PubMed Link: 34267653

Variant Present in the following documents:

• Main text
• fphar-12-614673.pdf

View BVdb publication page

---

EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance.

Cancers

Uribe, Mary Luz ML; Marrocco, Ilaria I; Yarden, Yosef Y

Publication Date: 2021-06-01

Variant appearance in text: HER2: T798I

PubMed Link: 34206026

Variant Present in the following documents:

• Main text
• cancers-13-02748.pdf

View BVdb publication page

---

Tyrosine Kinase Inhibitors Are Promising Therapeutic Tools for Cats with HER2-Positive Mammary Carcinoma.

Pharmaceutics

Gameiro, Andreia A; Almeida, Filipe F; Nascimento, Catarina C; Correia, Jorge J; Ferreira, Fernando F

Publication Date: 2021-03-06

Variant appearance in text: HER2: T798I

PubMed Link: 33800900

Variant Present in the following documents:

• Main text
• pharmaceutics-13-00346.pdf

View BVdb publication page

---

Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology

Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y

Publication Date: 2021-04-01

Variant appearance in text: ERBB2: T798I

PubMed Link: 33795819

Variant Present in the following documents:

• 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

---

Partial Response to Pyrotinib Plus Capecitabine in an Advanced Breast Cancer Patient with HER2 Amplification and R157W Mutation After Anti-HER2 Treatment: A Case Report and Literature Review.

Oncotargets And Therapy

Qu, Yanchun Y; Liu, Yufeng Y; Ding, Kailin K; Li, Yong Y; Hong, Xiaoyu X; Zhang, Haibo H

Publication Date: 2021

Variant appearance in text: HER2: T798I

PubMed Link: 33688205

Variant Present in the following documents:

• Main text
• ott-14-1581.pdf

View BVdb publication page

---

A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).

Ebiomedicine

Low, Joo-Leng JL; Lau, Dawn Pingxi DP; Zhang, Xiaoqian X; Kwang, Xue-Lin XL; Rohatgi, Neha N; Chan, Jane Vin JV; Chong, Fui-Teen FT; Wong, Stephen Qi Rong SQR; Leong, Hui-Sun HS; Thangavelu, Matan Thangavelu MT; Rikka, Shivaji S; Skanderup, Anders Martin Jacobsen AMJ; Tan, Daniel Shao Weng DSW; Periyasamy, Giridharan G; Koh, Judice Lie Yong JLY; Iyer, N Gopalakrishna NG; DasGupta, Ramanuj R

Publication Date: 2021-02

Variant appearance in text: ERBB2: T798I

PubMed Link: 33529999

Variant Present in the following documents:

• mmc2.xlsx, sheet 8

View BVdb publication page

---

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors.

British Journal Of Cancer

Conlon, Neil T NT; Kooijman, Jeffrey J JJ; van Gerwen, Suzanne J C SJC; Mulder, Winfried R WR; Zaman, Guido J R GJR; Diala, Irmina I; Eli, Lisa D LD; Lalani, Alshad S AS; Crown, John J; Collins, Denis M DM

Publication Date: 2021-03

Variant appearance in text: HER2: T798I

PubMed Link: 33473169

Variant Present in the following documents:

• Main text
• 41416_2020_Article_1257.pdf

View BVdb publication page

---

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors.

British Journal Of Cancer

Conlon, Neil T NT; Kooijman, Jeffrey J JJ; van Gerwen, Suzanne J C SJC; Mulder, Winfried R WR; Zaman, Guido J R GJR; Diala, Irmina I; Eli, Lisa D LD; Lalani, Alshad S AS; Crown, John J; Collins, Denis M DM

Publication Date: 2021-03

Variant appearance in text: HER2: T798I

PubMed Link: 33473169

Variant Present in the following documents:

• Main text
• 41416_2020_Article_1257.pdf

View BVdb publication page

---

Combining Neratinib with CDK4/6, mTOR, and MEK Inhibitors in Models of HER2-positive Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Zhao, Ming M; Scott, Stephen S; Evans, Kurt W KW; Yuca, Erkan E; Saridogan, Turcin T; Zheng, Xiaofeng X; Wang, Heping H; Korkut, Anil A; Cruz Pico, Christian X CX; Demirhan, Mehmet M; Kirby, Bryce B; Kopetz, Scott S; Diala, Irmina I; Lalani, Alshad S AS; Piha-Paul, Sarina S; Meric-Bernstam, Funda F

Publication Date: 2021-03-15

Variant appearance in text: ERBB2: T798I

PubMed Link: 33414137

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Attenuation of p53 mutant as an approach for treatment Her2-positive cancer.

Cell Death Discovery

Fedorova, Olga O; Daks, Alexandra A; Shuvalov, Oleg O; Kizenko, Alena A; Petukhov, Alexey A; Gnennaya, Yulia Y; Barlev, Nikolai N

Publication Date: 2020

Variant appearance in text: HER2: T798I

PubMed Link: 33083021

Variant Present in the following documents:

• 41420_2020_Article_337.pdf

View BVdb publication page

---

SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer.

Oncogene

Chen, Hao H; Libring, Sarah S; Ruddraraju, Kasi Viswanatharaju KV; Miao, Jinmin J; Solorio, Luis L; Zhang, Zhong-Yin ZY; Wendt, Michael K MK

Publication Date: 2020-12

Variant appearance in text: HER2: T798I

PubMed Link: 33033382

Variant Present in the following documents:

• 41388_2020_Article_1488.pdf

View BVdb publication page

---

ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia.

Leukemia

Joshi, Sunil K SK; Keck, Jamie M JM; Eide, Christopher A CA; Bottomly, Daniel D; Traer, Elie E; Tyner, Jeffrey W JW; McWeeney, Shannon K SK; Tognon, Cristina E CE; Druker, Brian J BJ

Publication Date: 2020-10

Variant appearance in text: ERBB2: T798I

PubMed Link: 32366937

Variant Present in the following documents:

• Main text
• 41375_2020_Article_844.pdf

View BVdb publication page

---

OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine.

Scientific Reports

López-Cortés, Andrés A; Paz-Y-Miño, César C; Guerrero, Santiago S; Cabrera-Andrade, Alejandro A; Barigye, Stephen J SJ; Munteanu, Cristian R CR; González-Díaz, Humberto H; Pazos, Alejandro A; Pérez-Castillo, Yunierkis Y; Tejera, Eduardo E

Publication Date: 2020-03-24

Variant appearance in text: ERBB2: T798I

PubMed Link: 32210335

Variant Present in the following documents:

• 41598_2020_62279_MOESM2_ESM.xlsx, sheet 40
• 41598_2020_62279_MOESM2_ESM.xlsx, sheet 33

View BVdb publication page

---

Identification of an Activating Mutation in the Extracellular Domain of HER2 Conferring Resistance to Pertuzumab.

Oncotargets And Therapy

Zhang, Ying Y; Wu, Shanshan S; Zhuang, Xinlei X; Weng, Gaoqi G; Fan, Jiansheng J; Yang, Xiaoyue X; Xu, Yingchun Y; Pan, Liqiang L; Hou, Tingjun T; Zhou, Zhan Z; Chen, Shuqing S

Publication Date: 2019

Variant appearance in text: HER2: T798I

PubMed Link: 31920346

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Monitoring treatment efficacy and resistance in breast cancer patients via circulating tumor DNA genomic profiling.

Molecular Genetics & Genomic Medicine

Chen, Zhanhong Z; Sun, Tian T; Yang, Ziyan Z; Zheng, Yabing Y; Yu, Ruoying R; Wu, Xue X; Yan, Junrong J; Shao, Yang W YW; Shao, Xiying X; Cao, Wenming W; Wang, Xiaojia X

Publication Date: 2020-02

Variant appearance in text: HER2: T798I

PubMed Link: 31867841

Variant Present in the following documents:

• MGG3-8-e1079.pdf

View BVdb publication page

---

Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer.

Cancer Discovery

Smyth, Lillian M LM; Piha-Paul, Sarina A SA; Won, Helen H HH; Schram, Alison M AM; Saura, Cristina C; Loi, Sherene S; Lu, Janice J; Shapiro, Geoffrey I GI; Juric, Dejan D; Mayer, Ingrid A IA; Arteaga, Carlos L CL; de la Fuente, Macarena I MI; Brufksy, Adam M AM; Spanggaard, Iben I; Mau-Sørensen, Morten M; Arnedos, Monica M; Moreno, Victor V; Boni, Valentina V; Sohn, Joohyuk J; Schwartzberg, Lee S LS; Gonzàlez-Farré, Xavier X; Cervantes, Andrés A; Bidard, François-Clement FC; Gorelick, Alexander N AN; Lanman, Richard B RB; Nagy, Rebecca J RJ; Ulaner, Gary A GA; Chandarlapaty, Sarat S; Jhaveri, Komal K; Gavrila, Elena I EI; Zimel, Catherine C; Selcuklu, S Duygu SD; Melcer, Myra M; Samoila, Aliaksandra A; Cai, Yanyan Y; Scaltriti, Maurizio M; Mann, Grace G; Xu, Feng F; Eli, Lisa D LD; Dujka, Melanie M; Lalani, Alshad S AS; Bryce, Richard R; Baselga, José J; Taylor, Barry S BS; Solit, David B DB; Meric-Bernstam, Funda F; Hyman, David M DM

Publication Date: 2020-02

Variant appearance in text: HER2: T798I

PubMed Link: 31806627

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A simple and flexible high-throughput method for the study of cardiomyocyte proliferation.

Scientific Reports

Neininger, Abigail C AC; Long, J Hunter JH; Baillargeon, Sophie M SM; Burnette, Dylan T DT

Publication Date: 2019-11-04

Variant appearance in text: ERBB2: T798I

PubMed Link: 31685907

Variant Present in the following documents:

• 41598_2019_52467_MOESM2_ESM.xls, sheet 1

View BVdb publication page

---

PLK1 targets NOTCH1 during DNA damage and mitotic progression.

The Journal Of Biological Chemistry

De Blasio, Carlo C; Zonfrilli, Azzurra A; Franchitto, Matteo M; Mariano, Germano G; Cialfi, Samantha S; Verma, Nagendra N; Checquolo, Saula S; Bellavia, Diana D; Palermo, Rocco R; Benelli, Dario D; Screpanti, Isabella I; Talora, Claudio C

Publication Date: 2019-11-22

Variant appearance in text: ERBB2: T798I

PubMed Link: 31597699

Variant Present in the following documents:

• supp_RA119.009881_153654_1_supp_400269_pyc513.xlsx, sheet 2

View BVdb publication page

---

Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer.

Cancers

Collins, Denis M DM; Conlon, Neil T NT; Kannan, Srinivasaraghavan S; Verma, Chandra S CS; Eli, Lisa D LD; Lalani, Alshad S AS; Crown, John J

Publication Date: 2019-05-28

Variant appearance in text: HER2: T798I

PubMed Link: 31141894

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Identification of Genetic Mutations in Cancer: Challenge and Opportunity in the New Era of Targeted Therapy.

Frontiers In Oncology

Jin, Jing J; Wu, Xu X; Yin, Jianhua J; Li, Mingxing M; Shen, Jing J; Li, Jing J; Zhao, Yueshui Y; Zhao, Qijie Q; Wu, Jingbo J; Wen, Qinglian Q; Cho, Chi Hin CH; Yi, Tao T; Xiao, Zhangang Z; Qu, Liping L

Publication Date: 2019

Variant appearance in text: HER2: T798I

PubMed Link: 31058077

Variant Present in the following documents:

• Main text
• fonc-09-00263.pdf

View BVdb publication page

---

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: ERBB2: T798I

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

---

Prevalence and role of HER2 mutations in cancer.

Pharmacology & Therapeutics

Cocco, Emiliano E; Lopez, Salvatore S; Santin, Alessandro D AD; Scaltriti, Maurizio M

Publication Date: 2019-07

Variant appearance in text: HER2: T798I

PubMed Link: 30951733

Variant Present in the following documents:

• Main text

View BVdb publication page

---

GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer.

Breast Cancer Research : Bcr

Vijay, Geraldine Vidhya GV; Zhao, Na N; Den Hollander, Petra P; Toneff, Mike J MJ; Joseph, Robiya R; Pietila, Mika M; Taube, Joseph H JH; Sarkar, Tapasree R TR; Ramirez-Pena, Esmeralda E; Werden, Steven J SJ; Shariati, Maryam M; Gao, Ruli R; Sobieski, Mary M; Stephan, Clifford C CC; Sphyris, Nathalie N; Miura, Noayuki N; Davies, Peter P; Chang, Jeffrey T JT; Soundararajan, Rama R; Rosen, Jeffrey M JM; Mani, Sendurai A SA

Publication Date: 2019-03-07

Variant appearance in text: ERBB2: T798I

PubMed Link: 30845991

Variant Present in the following documents:

• 13058_2019_1125_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

---

Human epidermal growth factor receptor targeted inhibitors for the treatment of ovarian cancer.

Cancer Biology & Medicine

Bonello, Maria M; Sims, Andrew Harvey AH; Langdon, Simon Peter SP

Publication Date: 2018-11

Variant appearance in text: HER2: T798I

PubMed Link: 30766749

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health.

Pharmacological Reviews

Cheng, Feixiong F; Liang, Han H; Butte, Atul J AJ; Eng, Charis C; Nussinov, Ruth R

Publication Date: 2019-01

Variant appearance in text: HER2: T798I

PubMed Link: 30545954

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Advances in HER2-Targeted Therapy: Novel Agents and Opportunities Beyond Breast and Gastric Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Meric-Bernstam, Funda F; Johnson, Amber M AM; Dumbrava, Ecaterina E Ileana EEI; Raghav, Kanwal K; Balaji, Kavitha K; Bhatt, Michelle M; Murthy, Rashmi K RK; Rodon, Jordi J; Piha-Paul, Sarina A SA

Publication Date: 2019-04-01

Variant appearance in text: HER2: T798I

PubMed Link: 30442682

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Receptor Tyrosine Kinase-Targeted Cancer Therapy.

International Journal Of Molecular Sciences

Yamaoka, Toshimitsu T; Kusumoto, Sojiro S; Ando, Koichi K; Ohba, Motoi M; Ohmori, Tohru T

Publication Date: 2018-11-06

Variant appearance in text: HER2: T798I

PubMed Link: 30404198

Variant Present in the following documents:

• Main text
• ijms-19-03491.pdf

View BVdb publication page

---

Cancer stem cells and HER2 positive breast cancer: The story so far.

Genes & Diseases

Shah, Deep D; Osipo, Clodia C

Publication Date: 2016-06

Variant appearance in text: HER2: T798I

PubMed Link: 30123819

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Personalized medicine in non-small cell lung cancer: a review from a pharmacogenomics perspective.

Acta Pharmaceutica Sinica. B

Jiang, Wenxiao W; Cai, Guiqing G; Hu, Peter C PC; Wang, Yue Y

Publication Date: 2018-07

Variant appearance in text: HER2: T798I

PubMed Link: 30109178

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports

Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS

Publication Date: 2018-04-03

Variant appearance in text: ERBB2: 2393C>T

PubMed Link: 29617658

Variant Present in the following documents:

• NIHMS958974-supplement-5.xlsx, sheet 1
• NIHMS958974-supplement-6.xlsx, sheet 1

View BVdb publication page

---

Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges.

Molecular Cancer

Butti, Ramesh R; Das, Sumit S; Gunasekaran, Vinoth Prasanna VP; Yadav, Amit Singh AS; Kumar, Dhiraj D; Kundu, Gopal C GC

Publication Date: 2018-02-19

Variant appearance in text: HER2: T798I

PubMed Link: 29455658

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genomic alterations of ERBB receptors in cancer: clinical implications.

Oncotarget

Mishra, Rosalin R; Hanker, Ariella B AB; Garrett, Joan T JT

Publication Date: 2017-12-26

Variant appearance in text: HER2: T798I

PubMed Link: 29371993

Variant Present in the following documents:

• Main text
• oncotarget-08-114371.pdf

View BVdb publication page

---

Activating HER2 mutations as emerging targets in multiple solid cancers.

Esmo Open

Connell, Claire M CM; Doherty, Gary J GJ

Publication Date: 2017

Variant appearance in text: HER2: T798I

PubMed Link: 29209536

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Molecular-Targeted Therapies for Epidermal Growth Factor Receptor and Its Resistance Mechanisms.

International Journal Of Molecular Sciences

Yamaoka, Toshimitsu T; Ohba, Motoi M; Ohmori, Tohru T

Publication Date: 2017-11-15

Variant appearance in text: HER2: T798I

PubMed Link: 29140271

Variant Present in the following documents:

• Main text
• ijms-18-02420.pdf

View BVdb publication page

---

Neratinib Efficacy and Circulating Tumor DNA Detection of HER2 Mutations in HER2 Nonamplified Metastatic Breast Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Ma, Cynthia X CX; Bose, Ron R; Gao, Feng F; Freedman, Rachel A RA; Telli, Melinda L ML; Kimmick, Gretchen G; Winer, Eric E; Naughton, Michael M; Goetz, Matthew P MP; Russell, Christy C; Tripathy, Debu D; Cobleigh, Melody M; Forero, Andres A; Pluard, Timothy J TJ; Anders, Carey C; Niravath, Polly Ann PA; Thomas, Shana S; Anderson, Jill J; Bumb, Caroline C; Banks, Kimberly C KC; Lanman, Richard B RB; Bryce, Richard R; Lalani, Alshad S AS; Pfeifer, John J; Hayes, Daniel F DF; Pegram, Mark M; Blackwell, Kimberly K; Bedard, Philippe L PL; Al-Kateb, Hussam H; Ellis, Matthew J C MJC

Publication Date: 2017-10-01

Variant appearance in text: HER2: T798I

PubMed Link: 28679771

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Precision medicine in breast cancer: reality or utopia?

Journal Of Translational Medicine

Bettaieb, Ali A; Paul, Catherine C; Plenchette, Stéphanie S; Shan, Jingxuan J; Chouchane, Lotfi L; Ghiringhelli, François F

Publication Date: 2017-06-17

Variant appearance in text: HER2: T798I

PubMed Link: 28623955

Variant Present in the following documents:

• Main text
• 12967_2017_Article_1239.pdf

View BVdb publication page

---