ERBB2 c.2524G>T ;(p.V842L)

Variant ID: 17-37881332-G-T

NM_004448.2(ERBB2):c.2524G>T;(p.V842L)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.

Cancer Research
Ishiyama, Noboru N; O'Connor, Matthew M; Salomatov, Andrei A; Romashko, Darlene D; Thakur, Shalabh S; Mentes, Ahmet A; Hopkins, Julia F JF; Frampton, Garrett M GM; Albacker, Lee A LA; Kohlmann, Anna A; Roberts, Christopher C; Buck, Elizabeth E
Publication Date: 2022-05-03

Variant appearance in text: HER2: V842L
PubMed Link: 35503682
Variant Present in the following documents:
  • Main text
  • 1531.pdf
View BVdb publication page



Prolonged Response to HER2-Directed Therapy in a Patient With HER2-Amplified, Rapidly Progressive Metastatic Colorectal Cancer.

Journal Of The National Comprehensive Cancer Network : Jnccn
Parikh, Aparna A; Atreya, Chloe C; Korn, W Michael WM; Venook, Alan P AP
Publication Date: 2017-01

Variant appearance in text: HER2: V842L
PubMed Link: 28040715
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic profiling of patient-derived colon cancer xenograft models.

Medicine
Lee, Won-Suk WS; Kim, Hye-Youn HY; Seok, Jae Yeon JY; Jang, Ho Hee HH; Park, Yeon Ho YH; Kim, So-Young SY; Shin, Dong Bok DB; Hong, Suntaek S
Publication Date: 2014-12

Variant appearance in text: HER2: V842l
PubMed Link: 25526474
Variant Present in the following documents:
  • Main text
  • medi-93-e298.pdf
View BVdb publication page