ERBB2 c.2689C>G ;(p.R897G)

Variant ID: 17-37881619-C-G

NM_004448.2(ERBB2):c.2689C>G;(p.R897G)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Comprehensive omic characterization of breast cancer in Mexican-Hispanic women.

Nature Communications
Romero-Cordoba, Sandra L SL; Salido-Guadarrama, Ivan I; Rebollar-Vega, Rosa R; Bautista-Piña, Veronica V; Dominguez-Reyes, Carlos C; Tenorio-Torres, Alberto A; Villegas-Carlos, Felipe F; Fernández-López, Juan C JC; Uribe-Figueroa, Laura L; Alfaro-Ruiz, Luis L; Hidalgo-Miranda, Alfredo A
Publication Date: 2021-04-14

Variant appearance in text: ERBB2: R897G
PubMed Link: 33854067
Variant Present in the following documents:
  • 41467_2021_22478_MOESM8_ESM.xlsx, sheet 9
View BVdb publication page



Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.

Nature Communications
Vandekerkhove, Gillian G; Lavoie, Jean-Michel JM; Annala, Matti M; Murtha, Andrew J AJ; Sundahl, Nora N; Walz, Simon S; Sano, Takeshi T; Taavitsainen, Sinja S; Ritch, Elie E; Fazli, Ladan L; Hurtado-Coll, Antonio A; Wang, Gang G; Nykter, Matti M; Black, Peter C PC; Todenhöfer, Tilman T; Ost, Piet P; Gibb, Ewan A EA; Chi, Kim N KN; Eigl, Bernhard J BJ; Wyatt, Alexander W AW
Publication Date: 2021-01-08

Variant appearance in text: ERBB2: R897G
PubMed Link: 33420073
Variant Present in the following documents:
  • 41467_2020_20493_MOESM3_ESM.xlsx, sheet 7
  • 41467_2020_20493_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non-inflammatory breast cancers.

Molecular Oncology
Bertucci, François F; Rypens, Charlotte C; Finetti, Pascal P; Guille, Arnaud A; Adélaïde, José J; Monneur, Audrey A; Carbuccia, Nadine N; Garnier, Séverine S; Dirix, Piet P; Gonçalves, Anthony A; Vermeulen, Peter P; Debeb, Bisrat G BG; Wang, Xiaoping X; Dirix, Luc L; Ueno, Naoto T NT; Viens, Patrice P; Cristofanilli, Massimo M; Chaffanet, Max M; Birnbaum, Daniel D; Van Laere, Steven S
Publication Date: 2020-03

Variant appearance in text: ERBB2: R897G
PubMed Link: 31854063
Variant Present in the following documents:
  • MOL2-14-504-s010.xlsx, sheet 1
View BVdb publication page



The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.

Biomolecules
Shin, Jung Won JW; Kim, Soohyun S; Ha, Suji S; Choi, Byungsan B; Kim, Seongyeong S; Im, Seock-Ah SA; Yoon, Tae-Young TY; Chung, Junho J
Publication Date: 2019-10-19

Variant appearance in text: HER2: R897G
PubMed Link: 31635022
Variant Present in the following documents:
  • Main text
  • biomolecules-09-00629.pdf
View BVdb publication page



Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines.

Molecular Oncology
Keller, Simone S; Zwingenberger, Gwen G; Ebert, Karolin K; Hasenauer, Jan J; Wasmuth, Jacqueline J; Maier, Dieter D; Haffner, Ivonne I; Schierle, Katrin K; Weirich, Gregor G; Luber, Birgit B
Publication Date: 2018-04

Variant appearance in text: ERBB2: R897G
PubMed Link: 29325228
Variant Present in the following documents:
  • MOL2-12-441-s001.pdf
View BVdb publication page



HER2 somatic mutations are associated with poor survival in HER2-negative breast cancers.

Cancer Science
Wang, Tonghui T; Xu, Ye Y; Sheng, Shuyan S; Yuan, Hua H; Ouyang, Tao T; Li, Jinfeng J; Wang, Tianfeng T; Fan, Zhaoqing Z; Fan, Tie T; Lin, Benyao B; Xie, Yuntao Y
Publication Date: 2017-04

Variant appearance in text: HER2: R897G
PubMed Link: 28164408
Variant Present in the following documents:
  • Main text
  • CAS-108-671.pdf
View BVdb publication page



Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer.

Oncotarget
Arienti, Chiara C; Zanoni, Michele M; Pignatta, Sara S; Del Rio, Alberto A; Carloni, Silvia S; Tebaldi, Michela M; Tedaldi, Gianluca G; Tesei, Anna A
Publication Date: 2016-04-05

Variant appearance in text: HER2: R897G
PubMed Link: 26919099
Variant Present in the following documents:
  • Main text
  • oncotarget-07-18424.pdf
View BVdb publication page