Publications:

---

miR-146a-5p Promotes Angiogenesis and Confers Trastuzumab Resistance in HER2+ Breast Cancer.

Cancers

Cabello, Paula P; Torres-Ruiz, Sandra S; Adam-Artigues, Anna A; Forés-Martos, Jaume J; Martínez, María Teresa MT; Hernando, Cristina C; Zazo, Sandra S; Madoz-Gúrpide, Juan J; Rovira, Ana A; Burgués, Octavio O; Rojo, Federico F; Albanell, Joan J; Lluch, Ana A; Bermejo, Begoña B; Cejalvo, Juan Miguel JM; Eroles, Pilar P

Publication Date: 2023-04-04

Variant appearance in text: HER2: H1047R

PubMed Link: 37046799

Variant Present in the following documents:

• cancers-15-02138.pdf

View BVdb publication page

---

Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine

Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M

Publication Date: 2023-04-11

Variant appearance in text: ERBB2: H1047R

PubMed Link: 37039257

Variant Present in the following documents:

• CAM4-12-11686-s002.xlsx, sheet 1

View BVdb publication page

---

Anti-tumor effects of low-dose metronomic vinorelbine in combination with alpelisib in breast cancer cells.

Excli Journal

Krajnak, Slavomir S; Trier, Jannis Patrik JP; Heinzmann, Pauline Friederike PF; Anic, Katharina K; Heimes, Anne-Sophie AS; Loewe, Amelie A; Schmidt, Marcus M; Battista, Marco Johannes MJ; Hasenburg, Annette A; Brenner, Walburgis W

Publication Date: 2023

Variant appearance in text: HER2: H1047R

PubMed Link: 36998707

Variant Present in the following documents:

• EXCLI-22-114.pdf

View BVdb publication page

---

Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: ERBB2: H1047R

PubMed Link: 36950276

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Phosphoinositide 3-Kinase (PI3K) Inhibitors and Breast Cancer: An Overview of Current Achievements.

Cancers

Bertucci, Alexandre A; Bertucci, François F; Gonçalves, Anthony A

Publication Date: 2023-02-23

Variant appearance in text: HER2: H1047R

PubMed Link: 36900211

Variant Present in the following documents:

• cancers-15-01416.pdf

View BVdb publication page

---

Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer.

Cellular And Molecular Life Sciences : Cmls

Hany, Dina D; Zoetemelk, Marloes M; Bhattacharya, Kaushik K; Nowak-Sliwinska, Patrycja P; Picard, Didier D

Publication Date: 2023-03-03

Variant appearance in text: HER2: H1047R

PubMed Link: 36869202

Variant Present in the following documents:

• 18_2023_4730_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

---

Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.

Jama Network Open

Naito, Yoichi Y; Sunami, Kuniko K; Kage, Hidenori H; Komine, Keigo K; Amano, Toraji T; Imai, Mitsuho M; Koyama, Takafumi T; Ennishi, Daisuke D; Kanai, Masashi M; Kenmotsu, Hirotsugu H; Maeda, Takahiro T; Morita, Sachi S; Sakai, Daisuke D; Watanabe, Kousuke K; Shirota, Hidekazu H; Kinoshita, Ichiro I; Yoshioka, Masashiro M; Mamesaya, Nobuaki N; Ito, Mamoru M; Kohsaka, Shinji S; Saigusa, Yusuke Y; Yamamoto, Kouji K; Hirata, Makoto M; Tsuchihara, Katsuya K; Yoshino, Takayuki T

Publication Date: 2022-12-01

Variant appearance in text: ERBB2: H1047R

PubMed Link: 36469316

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Molecular Basis and Rationale for the Use of Targeted Agents and Immunotherapy in Sinonasal Cancers.

Journal Of Clinical Medicine

Esposito, Andrea A; Stucchi, Erika E; Baronchelli, Maria M; Di Mauro, Pierluigi P; Ferrari, Marco M; Lorini, Luigi L; Gurizzan, Cristina C; London, Nyall Robert Jr NRJ; Hermsen, Mario M; Lechner, Matt M; Bossi, Paolo P

Publication Date: 2022-11-16

Variant appearance in text: ERBB2: H1047R

PubMed Link: 36431263

Variant Present in the following documents:

• jcm-11-06787.pdf

View BVdb publication page

---

First-in-human phase Ia study of the PI3Kα inhibitor CYH33 in patients with solid tumors.

Nature Communications

Wei, Xiao-Li XL; Liu, Fu-Rong FR; Liu, Ji-Hong JH; Zhao, Hong-Yun HY; Zhang, Yang Y; Wang, Zhi-Qiang ZQ; Qiu, Miao-Zhen MZ; Xu, Fei F; Yu, Qiu-Qiong QQ; Du, Yi-Wu YW; Shi, Yan-Xia YX; Wang, De-Sheng DS; Wang, Feng-Hua FH; Xu, Rui-Hua RH

Publication Date: 2022-11-16

Variant appearance in text: HER2: H1047R

PubMed Link: 36385120

Variant Present in the following documents:

• Main text
• 41467_2022_Article_34782.pdf

View BVdb publication page

---

Generation of a tree shrew breast cancer model using lentivirus expressing PIK3CA- H1047R.

Zoological Research

Zeng, Li L; Zhang, Hong-Yan HY; Yang, Chuan-Yu CY; Cheng, Zhuo Z; Jiang, Qiu-Yun QY; Luo, Yao Y; Li, Yi Y; Li, Fu-Bing FB; Chen, Ce-Shi CS

Publication Date: 2023-01-18

Variant appearance in text: HER-2: H1047R

PubMed Link: 36376241

Variant Present in the following documents:

• zr-44-1-94-S1.pdf

View BVdb publication page

---

A comparison of DNA sequencing and gene expression profiling to assist tissue of origin diagnosis in cancer of unknown primary.

The Journal Of Pathology

Posner, Atara A; Prall, Owen Wj OW; Sivakumaran, Tharani T; Etemadamoghadam, Dariush D; Thio, Niko N; Pattison, Andrew A; Balachander, Shiva S; Fisher, Krista K; Webb, Samantha S; Wood, Colin C; DeFazio, Anna A; Wilcken, Nicholas N; Gao, Bo B; Karapetis, Christos S CS; Singh, Madhu M; Collins, Ian M IM; Richardson, Gary G; Steer, Christopher C; Warren, Mark M; Karanth, Narayan N; Wright, Gavin G; Williams, Scott S; George, Joshy J; Hicks, Rodney J RJ; Boussioutas, Alex A; Gill, Anthony J AJ; Solomon, Benjamin J BJ; Xu, Huiling H; Fellowes, Andrew A; Fox, Stephen B SB; Schofield, Penelope P; Bowtell, David D; Mileshkin, Linda L; Tothill, Richard W RW

Publication Date: 2022-10-26

Variant appearance in text: HER2: His1047Arg

PubMed Link: 36287571

Variant Present in the following documents:

• PATH-259-81-s013.xlsx, sheet 2
• PATH-259-81-s011.xlsx, sheet 2

View BVdb publication page

---

Tinengotinib (TT-00420), a Novel Spectrum-Selective Small Molecule Kinase Inhibitor, Is Highly Active Against Triple Negative Breast Cancer.

Molecular Cancer Therapeutics

Peng, Peng P; Qiang, Xiaoyan X; Li, Guoyu G; Li, Lin L; Ni, Shumao S; Yu, Qi Q; Sourd, Laura L; Marangoni, Elisabetta E; Hu, Chao C; Wang, Dong D; Wu, Di D; Wu, Frank F

Publication Date: 2022-10-12

Variant appearance in text: HER2: H1047R

PubMed Link: 36223547

Variant Present in the following documents:

• 205.pdf

View BVdb publication page

---

Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer.

British Journal Of Cancer

Fernandez-Garcia, Daniel D; Nteliopoulos, Georgios G; Hastings, Robert K RK; Rushton, Amelia A; Page, Karen K; Allsopp, Rebecca C RC; Ambasager, Bana B; Gleason, Kelly K; Guttery, David S DS; Ali, Simak S; Charles Coombes, R R; Shaw, Jacqueline A JA

Publication Date: 2022-11

Variant appearance in text: ERBB2: H1047R

PubMed Link: 36088510

Variant Present in the following documents:

• 41416_2022_1962_MOESM2_ESM.xlsx, sheet 5

View BVdb publication page

---

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications

Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A

Publication Date: 2022-07-13

Variant appearance in text: ERBB2: 3140A>G; His1047Arg

PubMed Link: 35831314

Variant Present in the following documents:

• 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

---

Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications

Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ

Publication Date: 2022-05-13

Variant appearance in text: ERBB2: H1047R

PubMed Link: 35562349

Variant Present in the following documents:

• 41467_2022_30342_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

---

Analysis of PIK3CA Mutation Concordance and Frequency in Primary and Different Distant Metastatic Sites in Breast Cancer.

Cancer Research And Treatment

Park, Jieun J; Cho, Soo Youn SY; Chang, Eun Sol ES; Sung, Minjung M; Song, Ji-Young JY; Jung, Kyungsoo K; Kim, Sung-Su SS; Shin, Young Kee YK; Choi, Yoon-La YL

Publication Date: 2022-04-20

Variant appearance in text: HER2: H1047R

PubMed Link: 35468270

Variant Present in the following documents:

• crt-2022-001-S2-Table.pdf

View BVdb publication page

---

Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα.

Journal Of The American Chemical Society

Borsari, Chiara C; Keles, Erhan E; McPhail, Jacob A JA; Schaefer, Alexander A; Sriramaratnam, Rohitha R; Goch, Wojciech W; Schaefer, Thorsten T; De Pascale, Martina M; Bal, Wojciech W; Gstaiger, Matthias M; Burke, John E JE; Wymann, Matthias P MP

Publication Date: 2022-04-13

Variant appearance in text: HER2: H1047R

PubMed Link: 35353516

Variant Present in the following documents:

• ja1c13568.pdf

View BVdb publication page

---

The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: ERBB2: His1047Arg

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

---

Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases.

Cancers

Lim, Malcolm M; Nguyen, Tam H TH; Niland, Colleen C; Reid, Lynne E LE; Jat, Parmjit S PS; Saunus, Jodi M JM; Lakhani, Sunil R SR

Publication Date: 2022-01-21

Variant appearance in text: HER2: H1047R

PubMed Link: 35158800

Variant Present in the following documents:

• cancers-14-00533.pdf

View BVdb publication page

---

Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases.

Cancers

Lim, Malcolm M; Nguyen, Tam H TH; Niland, Colleen C; Reid, Lynne E LE; Jat, Parmjit S PS; Saunus, Jodi M JM; Lakhani, Sunil R SR

Publication Date: 2022-01-21

Variant appearance in text: HER2: H1047R

PubMed Link: 35158800

Variant Present in the following documents:

• cancers-14-00533.pdf

View BVdb publication page

---

How Lineage Tracing Studies Can Unveil Tumor Heterogeneity in Breast Cancer.

Biomedicines

Vinuesa-Pitarch, Elena E; Ortega-Álvarez, Daniel D; Rodilla, Verónica V

Publication Date: 2021-12-21

Variant appearance in text: HER2: H1047R

PubMed Link: 35052683

Variant Present in the following documents:

• Main text

View BVdb publication page

---

How Lineage Tracing Studies Can Unveil Tumor Heterogeneity in Breast Cancer.

Biomedicines

Vinuesa-Pitarch, Elena E; Ortega-Álvarez, Daniel D; Rodilla, Verónica V

Publication Date: 2021-12-21

Variant appearance in text: HER2: H1047R

PubMed Link: 35052683

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Fitzpatrick, Amanda A; Iravani, Marjan M; Mills, Adam A; Childs, Lucy L; Alaguthurai, Thanussuyah T; Clifford, Angela A; Garcia-Murillas, Isaac I; Van Laere, Steven S; Dirix, Luc L; Harries, Mark M; Okines, Alicia A; Turner, Nicholas C NC; Haider, Syed S; Tutt, Andrew N J ANJ; Isacke, Clare M CM

Publication Date: 2022-03-15

Variant appearance in text: ERBB2: H1047R

PubMed Link: 34921020

Variant Present in the following documents:

• 1180.pdf

View BVdb publication page

---

Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms.

Nature Cancer

Lehtiö, Janne J; Arslan, Taner T; Siavelis, Ioannis I; Pan, Yanbo Y; Socciarelli, Fabio F; Berkovska, Olena O; Umer, Husen M HM; Mermelekas, Georgios G; Pirmoradian, Mohammad M; Jönsson, Mats M; Brunnström, Hans H; Brustugun, Odd Terje OT; Purohit, Krishna Pinganksha KP; Cunningham, Richard R; Foroughi Asl, Hassan H; Isaksson, Sofi S; Arbajian, Elsa E; Aine, Mattias M; Karlsson, Anna A; Kotevska, Marija M; Gram Hansen, Carsten C; Drageset Haakensen, Vilde V; Helland, Åslaug Å; Tamborero, David D; Johansson, Henrik J HJ; Branca, Rui M RM; Planck, Maria M; Staaf, Johan J; Orre, Lukas M LM

Publication Date: 2021-11

Variant appearance in text: ERBB2: 3140A>G; His1047Arg

PubMed Link: 34870237

Variant Present in the following documents:

• EMS133264-supplement-Supplementary_Tables.xlsx, sheet 9

View BVdb publication page

---

Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Clinicopathologic Analysis with Evaluation of the E-Cadherin/β-Catenin Complex and Associated Genetic Alterations.

Case Reports In Pathology

Del Valle Estopinal, Maria M; Middleton, Lavinia P LP; Esmaeli, Bita B; Patel, Keyur P KP; Nowroozizadeh, Sara S; Williams, Michelle D MD

Publication Date: 2021

Variant appearance in text: ERBB2: 3140A>G; H1047R

PubMed Link: 34804623

Variant Present in the following documents:

• CRIPA2021-6628150.pdf

View BVdb publication page

---

Oncomine™ Comprehensive Assay v3 vs. Oncomine™ Comprehensive Assay Plus.

Cancers

Vestergaard, Lau K LK; Oliveira, Douglas N P DNP; Poulsen, Tim S TS; Høgdall, Claus K CK; Høgdall, Estrid V EV

Publication Date: 2021-10-18

Variant appearance in text: ERBB2: H1047R

PubMed Link: 34680378

Variant Present in the following documents:

• Main text
• cancers-13-05230.pdf

View BVdb publication page

---

Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action.

Nature Communications

Kast, Florian F; Schwill, Martin M; Stüber, Jakob C JC; Pfundstein, Svende S; Nagy-Davidescu, Gabriela G; Rodríguez, Josep M Monné JMM; Seehusen, Frauke F; Richter, Christian P CP; Honegger, Annemarie A; Hartmann, Karen Patricia KP; Weber, Thomas G TG; Kroener, Felix F; Ernst, Patrick P; Piehler, Jacob J; Plückthun, Andreas A

Publication Date: 2021-06-18

Variant appearance in text: ERBB2: H1047R

PubMed Link: 34145240

Variant Present in the following documents:

• 41467_2021_Article_23948.pdf

View BVdb publication page

---

Recent Advances in Implantation-Based Genetic Modeling of Biliary Carcinogenesis in Mice.

Cancers

Izumiya, Masashi M; Kato, Shingo S; Hippo, Yoshitaka Y

Publication Date: 2021-05-11

Variant appearance in text: ERBB2: H1047R

PubMed Link: 34064809

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity.

Scientific Reports

Phung, Tanya N TN; Webster, Timothy H TH; Lenkiewicz, Elizabeth E; Malasi, Smriti S; Andreozzi, Mariacarla M; McCullough, Ann E AE; Anderson, Karen S KS; Pockaj, Barbara A BA; Wilson, Melissa A MA; Barrett, Michael T MT

Publication Date: 2021-05-19

Variant appearance in text: ERBB2: H1047R

PubMed Link: 34011996

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Precision modeling of gall bladder cancer patients in mice based on orthotopic implantation of organoid-derived tumor buds.

Oncogenesis

Kato, Shingo S; Fushimi, Kentaro K; Yabuki, Yuichiro Y; Maru, Yoshiaki Y; Hasegawa, Sho S; Matsuura, Tetsuya T; Kurotaki, Daisuke D; Suzuki, Akihiro A; Kobayashi, Noritoshi N; Yoneda, Masato M; Higurashi, Takuma T; Enaka, Makiko M; Tamura, Tomohiko T; Hippo, Yoshitaka Y; Nakajima, Atsushi A

Publication Date: 2021-04-17

Variant appearance in text: ERBB2: H1047R

PubMed Link: 33866327

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Dual inhibition of TGFβ and AXL as a novel therapy for human colorectal adenocarcinoma with mesenchymal phenotype.

Medical Oncology (Northwood, London, England)

Ciardiello, Davide D; Blauensteiner, Bernadette B; Matrone, Nunzia N; Belli, Valentina V; Mohr, Thomas T; Vitiello, Pietro Paolo PP; Martini, Giulia G; Poliero, Luca L; Cardone, Claudia C; Napolitano, Stefania S; De Falco, Vincenzo V; Giunta, Emilio Francesco EF; Ciaramella, Vincenza V; Corte, Carminia Della CD; Barra, Giusi G; Selvaggi, Francesco F; Franco, Renato R; Marino, Federica Zito FZ; Cuomo, Antonio A; Morgillo, Floriana F; Troiani, Teresa T; Sibilia, Maria M; Ciardiello, Fortunato F; Martinelli, Erika E

Publication Date: 2021-02-11

Variant appearance in text: HER2: H1047R

PubMed Link: 33570712

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Development and validation of a multigene variant profiling assay to guide targeted and immuno therapy selection in solid tumors.

Plos One

Akolkar, Dadasaheb D; Patil, Darshana D; Srivastava, Navin N; Patil, Revati R; Datta, Vineet V; Apurwa, Sachin S; Yashwante, Nitin N; Dhasarathan, Raja R; Gosavi, Rahul R; John, Jinumary J; Khan, Shabishta S; Jadhav, Ninad N; Mene, Priti P; Ahire, Dhanashri D; Pawar, Sushant S; Bodke, Harshal H; Sahoo, Subhraline S; Nile, Arun A; Saindane, Dinesh D; Darokar, Harshal H; Devhare, Pradip P; Srinivasan, Ajay A; Datar, Rajan R

Publication Date: 2021

Variant appearance in text: ERBB2: H1047R

PubMed Link: 33556149

Variant Present in the following documents:

• pone.0246048.s006.xlsx, sheet 1

View BVdb publication page

---

The mutational repertoire of uterine sarcomas and carcinosarcomas in a Brazilian cohort: A preliminary study.

Clinics (Sao Paulo, Brazil)

da Costa, Leonardo Tomiatti LT; Dos Anjos, Laura Gonzalez LG; Kagohara, Luciane Tsukamoto LT; Torrezan, Giovana Tardin GT; De Paula, Claudia A Andrade CAA; Baracat, Edmund Chada EC; Carraro, Dirce Maria DM; Carvalho, Katia Candido KC

Publication Date: 2021

Variant appearance in text: HER2: His1047Arg

PubMed Link: 33503190

Variant Present in the following documents:

• cln-76-2324.pdf

View BVdb publication page

---

Genomic Landscape and Targeted Treatment of Gallbladder Cancer: Results of a First Ongoing Prospective Study.

South Asian Journal Of Cancer

Patel, Amol A; Soneji, Dharmesh D; Singh, Harinder Pal HP; Kumar, Manish M; Bandyopadhyay, Arnab A; Mathur, Ankit A; Sharma, Anuj A; Gahlot, Gaurav Prakash Singh GPS; Ms, Shivashankara S; Guleria, Bhupesh B; Nair, Rajesh R; Bhuva, Dipen D; Pandalanghat, Suresh S

Publication Date: 2020-06

Variant appearance in text: ERBB2: H1047R

PubMed Link: 33354548

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Methodological Advancements for Investigating Intra-tumoral Heterogeneity in Breast Cancer at the Bench and Bedside.

Journal Of Mammary Gland Biology And Neoplasia

Baek, Mokryun M; Chang, Jeffrey T JT; Echeverria, Gloria V GV

Publication Date: 2020-12

Variant appearance in text: HER2: H1047R

PubMed Link: 33300087

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Mass Spectrometry as a Highly Sensitive Method for Specific Circulating Tumor DNA Analysis in NSCLC: A Comparison Study.

Cancers

Lamy, Pierre-Jean PJ; van der Leest, Paul P; Lozano, Nicolas N; Becht, Catherine C; Duboeuf, Frédérique F; Groen, Harry J M HJM; Hilgers, Werner W; Pourel, Nicolas N; Rifaela, Naomi N; Schuuring, Ed E; Alix-Panabières, Catherine C

Publication Date: 2020-10-16

Variant appearance in text: ERBB2: 3140A>G

PubMed Link: 33081150

Variant Present in the following documents:

• cancers-12-03002-s001.pdf

View BVdb publication page

---

Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants.

Communications Biology

Inagaki-Kawata, Yukiko Y; Yoshida, Kenichi K; Kawaguchi-Sakita, Nobuko N; Kawashima, Masahiro M; Nishimura, Tomomi T; Senda, Noriko N; Shiozawa, Yusuke Y; Takeuchi, Yasuhide Y; Inoue, Yoshikage Y; Sato-Otsubo, Aiko A; Fujii, Yoichi Y; Nannya, Yasuhito Y; Suzuki, Eiji E; Takada, Masahiro M; Tanaka, Hiroko H; Shiraishi, Yuichi Y; Chiba, Kenichi K; Kataoka, Yuki Y; Torii, Masae M; Yoshibayashi, Hiroshi H; Yamagami, Kazuhiko K; Okamura, Ryuji R; Moriguchi, Yoshio Y; Kato, Hironori H; Tsuyuki, Shigeru S; Yamauchi, Akira A; Suwa, Hirofumi H; Inamoto, Takashi T; Miyano, Satoru S; Ogawa, Seishi S; Toi, Masakazu M

Publication Date: 2020-10-16

Variant appearance in text: ERBB2: H1047R

PubMed Link: 33067557

Variant Present in the following documents:

• 42003_2020_1301_MOESM1_ESM.pdf

View BVdb publication page

---

Deep phylogeny of cancer drivers and compensatory mutations.

Communications Biology

Rochman, Nash D ND; Wolf, Yuri I YI; Koonin, Eugene V EV

Publication Date: 2020-10-02

Variant appearance in text: HER2: H1047R

PubMed Link: 33009502

Variant Present in the following documents:

• 42003_2020_1276_MOESM14_ESM.xlsx, sheet 1

View BVdb publication page

---

Landscape of circulating tumour DNA in metastatic breast cancer.

Ebiomedicine

Davis, Andrew A AA; Jacob, Saya S; Gerratana, Lorenzo L; Shah, Ami N AN; Wehbe, Firas F; Katam, Neelima N; Zhang, Qiang Q; Flaum, Lisa L; Siziopikou, Kalliopi P KP; Platanias, Leonidas C LC; Gradishar, William J WJ; Behdad, Amir A; Cristofanilli, Massimo M

Publication Date: 2020-08

Variant appearance in text: ERBB2: H1047R

PubMed Link: 32707446

Variant Present in the following documents:

• main.pdf

View BVdb publication page

---

Genetic mutation profile of Chinese HER2-positive breast cancers and genetic predictors of responses to Neoadjuvant anti-HER2 therapy.

Breast Cancer Research And Treatment

Li, Kai K; Liao, Ning N; Chen, Bo B; Zhang, Guochun G; Wang, Yulei Y; Guo, Liping L; Wei, Guangnan G; Jia, Minghan M; Wen, Lingzhu L; Ren, Chongyang C; Cao, Li L; Mok, Hsiaopei H; Li, Cheukfai C; Lin, Jiali J; Chen, Xiaoqing X; Zhang, Zhou Z; Hou, Ting T; Li, Min M; Liu, Jing J; Balch, Charles M CM; Liao, Ning N

Publication Date: 2020-09

Variant appearance in text: HER2: H1047R

PubMed Link: 32638235

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2- Metastatic Breast Cancer.

International Journal Of Breast Cancer

Anderson, Elizabeth J EJ; Mollon, Lea E LE; Dean, Joni L JL; Warholak, Terri L TL; Aizer, Ayal A; Platt, Emma A EA; Tang, Derek H DH; Davis, Lisa E LE

Publication Date: 2020

Variant appearance in text: HER2: H1047R

PubMed Link: 32637176

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Evaluation of circulating tumor DNA as a biomarker in pancreatic cancer with liver metastasis.

Plos One

Uesato, Yasunori Y; Sasahira, Naoki N; Ozaka, Masato M; Sasaki, Takashi T; Takatsuki, Mitsuhisa M; Zembutsu, Hitoshi H

Publication Date: 2020

Variant appearance in text: ERBB2: H1047R

PubMed Link: 32614932

Variant Present in the following documents:

• pone.0235623.s001.xlsx, sheet 1

View BVdb publication page

---

Identification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and Prognostic Purposes: A Computational Approach.

Cancer Informatics

D'Afonseca, Vívian V; Arencibia, Ariel D AD; Echeverría-Vega, Alex A; Cerpa, Leslie L; Cayún, Juan P JP; Varela, Nelson M NM; Salazar, Marcela M; Quiñones, Luis A LA

Publication Date: 2020

Variant appearance in text: ERBB2: H1047R

PubMed Link: 32546937

Variant Present in the following documents:

• 10.1177_1176935120922154.pdf

View BVdb publication page

---

Clinical Multigene Panel Sequencing Identifies Distinct Mutational Association Patterns in Metastatic Colorectal Cancer.

Frontiers In Oncology

Belardinilli, Francesca F; Capalbo, Carlo C; Malapelle, Umberto U; Pisapia, Pasquale P; Raimondo, Domenico D; Milanetti, Edoardo E; Yasaman, Mahdavian M; Liccardi, Carlotta C; Paci, Paola P; Sibilio, Pasquale P; Pepe, Francesco F; Bonfiglio, Caterina C; Mezi, Silvia S; Magri, Valentina V; Coppa, Anna A; Nicolussi, Arianna A; Gradilone, Angela A; Petroni, Marialaura M; Di Giulio, Stefano S; Fabretti, Francesca F; Infante, Paola P; Coni, Sonia S; Canettieri, Gianluca G; Troncone, Giancarlo G; Giannini, Giuseppe G

Publication Date: 2020

Variant appearance in text: ERBB2: H1047R

PubMed Link: 32457828

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

---

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer.

Nature Genetics

Wagner, Alex H AH; Walsh, Brian B; Mayfield, Georgia G; Tamborero, David D; Sonkin, Dmitriy D; Krysiak, Kilannin K; Deu-Pons, Jordi J; Duren, Ryan P RP; Gao, Jianjiong J; McMurry, Julie J; Patterson, Sara S; Del Vecchio Fitz, Catherine C; Pitel, Beth A BA; Sezerman, Ozman U OU; Ellrott, Kyle K; Warner, Jeremy L JL; Rieke, Damian T DT; Aittokallio, Tero T; Cerami, Ethan E; Ritter, Deborah I DI; Schriml, Lynn M LM; Freimuth, Robert R RR; Haendel, Melissa M; Raca, Gordana G; Madhavan, Subha S; Baudis, Michael M; Beckmann, Jacques S JS; Dienstmann, Rodrigo R; Chakravarty, Debyani D; Li, Xuan Shirley XS; Mockus, Susan S; Elemento, Olivier O; Schultz, Nikolaus N; Lopez-Bigas, Nuria N; Lawler, Mark M; Goecks, Jeremy J; Griffith, Malachi M; Griffith, Obi L OL; Margolin, Adam A AA; ,

Publication Date: 2020-04

Variant appearance in text: ERBB2: H1047R

PubMed Link: 32246132

Variant Present in the following documents:

• Main text
• 41588_2020_Article_603.pdf

View BVdb publication page

---

LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype.

Frontiers In Oncology

Cao, Canhui C; Lin, Shitong S; Zhi, Wenhua W; Lazare, Cordelle C; Meng, Yifan Y; Wu, Ping P; Gao, Peipei P; Wei, Juncheng J; Wu, Peng P

Publication Date: 2020

Variant appearance in text: ERBB2: H1047R

PubMed Link: 32211324

Variant Present in the following documents:

• Table_1.xls, sheet 6

View BVdb publication page

---

Breast cancer organoids from a patient with giant papillary carcinoma as a high-fidelity model.

Cancer Cell International

Li, Xuelu X; Pan, Bo B; Song, Xiaoqing X; Li, Ning N; Zhao, Dongyi D; Li, Man M; Zhao, Zuowei Z

Publication Date: 2020

Variant appearance in text: HER2: H1047R

PubMed Link: 32206037

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Comprehensive pharmacogenomic characterization of gastric cancer.

Genome Medicine

Sa, Jason K JK; Hong, Jung Yong JY; Lee, In-Kyoung IK; Kim, Ju-Sun JS; Sim, Moon-Hee MH; Kim, Ha Jung HJ; An, Ji Yeong JY; Sohn, Tae Sung TS; Lee, Joon Ho JH; Bae, Jae Moon JM; Kim, Sung S; Kim, Kyoung-Mee KM; Kim, Seung Tae ST; Park, Se Hoon SH; Park, Joon Oh JO; Lim, Ho Yeong HY; Kang, Won Ki WK; Her, Nam-Gu NG; Lee, Yeri Y; Cho, Hee Jin HJ; Shin, Yong Jae YJ; Kim, Misuk M; Koo, Harim H; Kim, Mirinae M; Seo, Yun Jee YJ; Kim, Ja Yeon JY; Choi, Min-Gew MG; Nam, Do-Hyun DH; Lee, Jeeyun J

Publication Date: 2020-02-18

Variant appearance in text: ERBB2: H1047R

PubMed Link: 32070411

Variant Present in the following documents:

• 13073_2020_717_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

---

Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer.

Therapeutic Advances In Medical Oncology

Canonici, Alexandra A; Browne, Alacoque L AL; Ibrahim, Mohamed F K MFK; Fanning, Kevin P KP; Roche, Sandra S; Conlon, Neil T NT; O'Neill, Fiona F; Meiller, Justine J; Cremona, Mattia M; Morgan, Clare C; Hennessy, Bryan T BT; Eustace, Alex J AJ; Solca, Flavio F; O'Donovan, Norma N; Crown, John J

Publication Date: 2020

Variant appearance in text: HER2: H1047R

PubMed Link: 32064003

Variant Present in the following documents:

• Main text
• 10.1177_1758835919897546.pdf

View BVdb publication page

---

Development and validation of a targeted gene sequencing panel for application to disparate cancers.

Scientific Reports

McCabe, Mark J MJ; Gauthier, Marie-Emilie A MA; Chan, Chia-Ling CL; Thompson, Tanya J TJ; De Sousa, Sunita M C SMC; Puttick, Clare C; Grady, John P JP; Gayevskiy, Velimir V; Tao, Jiang J; Ying, Kevin K; Cipponi, Arcadi A; Deng, Niantao N; Swarbrick, Alex A; Thomas, Melissa L ML; Lord, Reginald V RV; Johns, Amber L AL; Kohonen-Corish, Maija M; O'Toole, Sandra A SA; Clark, Jonathan J; Mueller, Simon A SA; Gupta, Ruta R; McCormack, Ann I AI; Dinger, Marcel E ME; Cowley, Mark J MJ; ,

Publication Date: 2019-11-19

Variant appearance in text: ERBB2: H1047R

PubMed Link: 31745186

Variant Present in the following documents:

• Main text
• 41598_2019_Article_52000.pdf

View BVdb publication page

---

Mutation profiling of cancer drivers in Brazilian colorectal cancer.

Scientific Reports

Dos Santos, Wellington W; Sobanski, Thais T; de Carvalho, Ana Carolina AC; Evangelista, Adriane Feijó AF; Matsushita, Marcus M; Berardinelli, Gustavo Nóriz GN; de Oliveira, Marco Antonio MA; Reis, Rui Manuel RM; Guimarães, Denise Peixoto DP

Publication Date: 2019-09-23

Variant appearance in text: ERBB2: His1047Arg

PubMed Link: 31548566

Variant Present in the following documents:

• 41598_2019_49611_MOESM1_ESM.pdf

View BVdb publication page

---

Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress.

Redox Biology

Wang, Yang Y; Li, Juan J; Gao, Ya Y; Luo, Yue Y; Luo, Hong H; Wang, Liang L; Yi, Yong Y; Yuan, Zengqiang Z; Jim Xiao, Zhi-Xiong ZX

Publication Date: 2019-09

Variant appearance in text: HER2: H1047R

PubMed Link: 31212215

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Challenges of Providing Concordant Interpretation of Somatic Variants in Non-Small Cell Lung Cancer: A Multicenter Study.

Journal Of Cancer

Gao, Peng P; Zhang, Rui R; Li, Ziyang Z; Ding, Jiansheng J; Xie, Jiehong J; Li, Jinming J

Publication Date: 2019

Variant appearance in text: ERBB2: 3140A>G; His1047Arg

PubMed Link: 31205538

Variant Present in the following documents:

• jcav10p1814s1.xls, sheet 10

View BVdb publication page

---

Role of Integrins in Resistance to Therapies Targeting Growth Factor Receptors in Cancer.

Cancers

Cruz da Silva, Elisabete E; Dontenwill, Monique M; Choulier, Laurence L; Lehmann, Maxime M

Publication Date: 2019-05-17

Variant appearance in text: HER2: H1047R

PubMed Link: 31109009

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Eich, Marie-Lisa ML; Rodriguez Pena, Maria Del Carmen MDC; Springer, Simeon U SU; Taheri, Diana D; Tregnago, Aline C AC; Salles, Daniela C DC; Bezerra, Stephania Martins SM; Cunha, Isabela W IW; Fujita, Kazutoshi K; Ertoy, Dilek D; Bivalacqua, Trinity J TJ; Tomasetti, Cristian C; Papadopoulos, Nickolas N; Kinzler, Ken W KW; Vogelstein, Bert B; Netto, George J GJ

Publication Date: 2019-10

Variant appearance in text: ERBB2: H1047R

PubMed Link: 31028363

Variant Present in the following documents:

• NIHMS1525315-supplement-2.xlsx, sheet 1

View BVdb publication page

---

Application of cell-free DNA for genomic tumor profiling: a feasibility study.

Oncotarget

Ahlborn, Lise B LB; Rohrberg, Kristoffer S KS; Gabrielaite, Migle M; Tuxen, Ida V IV; Yde, Christina W CW; Spanggaard, Iben I; Santoni-Rugiu, Eric E; Nielsen, Finn C FC; Lassen, Ulrik U; Mau-Sorensen, Morten M; Østrup, Olga O

Publication Date: 2019-02-15

Variant appearance in text: ERBB2: H1047R

PubMed Link: 30858924

Variant Present in the following documents:

• oncotarget-10-1388-s002.xls, sheet 5

View BVdb publication page

---

Chronological occurrence of PI3KCA mutations in breast cancer liver metastases after repeat partial liver resection.

Bmc Cancer

Ruiz, Aldrick A; Sebagh, Mylène M; Saffroy, Raphaël R; Allard, Marc-Antoine MA; Bosselut, Nelly N; Hardoin, Giulia G; Vasseur, Julie J; Hamelin, Jocelyne J; Adam, René R; Morère, Jean-François JF; Lemoine, Antoinette A

Publication Date: 2019-02-22

Variant appearance in text: HER2: H1047R

PubMed Link: 30795751

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines.

Slas Discovery : Advancing Life Sciences R & D

Warchal, Scott J SJ; Dawson, John C JC; Carragher, Neil O NO

Publication Date: 2019-03

Variant appearance in text: HER2: H1047R

PubMed Link: 30694704

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genomic alterations at the basis of treatment resistance in metastatic breast cancer: clinical applications.

Oncotarget

Toss, Angela A; Piacentini, Federico F; Cortesi, Laura L; Artuso, Lucia L; Bernardis, Isabella I; Parenti, Sandra S; Tenedini, Elena E; Ficarra, Guido G; Maiorana, Antonino A; Iannone, Anna A; Omarini, Claudia C; Moscetti, Luca L; Cristofanilli, Massimo M; Federico, Massimo M; Tagliafico, Enrico E

Publication Date: 2018-08-03

Variant appearance in text: ERBB2: 3140A>G

PubMed Link: 30167082

Variant Present in the following documents:

• Main text
• oncotarget-09-31606.pdf

View BVdb publication page

---

The Dilemma of HER2 Double-equivocal Breast Carcinomas: Genomic Profiling and Implications for Treatment.

The American Journal Of Surgical Pathology

Marchiò, Caterina C; Dell'Orto, Patrizia P; Annaratone, Laura L; Geyer, Felipe C FC; Venesio, Tiziana T; Berrino, Enrico E; Verdun di Cantogno, Ludovica L; Garofoli, Andrea A; Rangel, Nelson N; Casorzo, Laura L; dell'Aglio, Carmine C; Gugliotta, Patrizia P; Trisolini, Elena E; Beano, Alessandra A; Pietribiasi, Francesca F; Orlassino, Renzo R; Cassoni, Paola P; Pich, Achille A; Montemurro, Filippo F; Mottolese, Marcella M; Vincent-Salomon, Anne A; Penault-Llorca, Frédérique F; Medico, Enzo E; Ng, Charlotte K Y CKY; Viale, Giuseppe G; Sapino, Anna A

Publication Date: 2018-09

Variant appearance in text: HER2: 3140A>G

PubMed Link: 29975246

Variant Present in the following documents:

• pas-42-1190.pdf

View BVdb publication page

---

Trastuzumab upregulates PD-L1 as a potential mechanism of trastuzumab resistance through engagement of immune effector cells and stimulation of IFNγ secretion.

Cancer Letters

Chaganty, Bharat K R BKR; Qiu, Songbo S; Gest, Anneliese A; Lu, Yang Y; Ivan, Cristina C; Calin, George A GA; Weiner, Louis M LM; Fan, Zhen Z

Publication Date: 2018-08-28

Variant appearance in text: HER2: H1047R

PubMed Link: 29746929

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A robust targeted sequencing approach for low input and variable quality DNA from clinical samples.

Npj Genomic Medicine

So, Austin P AP; Vilborg, Anna A; Bouhlal, Yosr Y; Koehler, Ryan T RT; Grimes, Susan M SM; Pouliot, Yannick Y; Mendoza, Daniel D; Ziegle, Janet J; Stein, Jason J; Goodsaid, Federico F; Lucero, Michael Y MY; De La Vega, Francisco M FM; Ji, Hanlee P HP

Publication Date: 2018

Variant appearance in text: ERBB2: H1047R

PubMed Link: 29354287

Variant Present in the following documents:

• 41525_2017_41_MOESM1_ESM.pdf

View BVdb publication page

---

Targeting bromodomain and extraterminal proteins in breast cancer.

Pharmacological Research

Sahni, Jennifer M JM; Keri, Ruth A RA

Publication Date: 2018-03

Variant appearance in text: HER2: H1047R

PubMed Link: 29154989

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Circulating cell-free DNA and circulating tumor cells, the "liquid biopsies" in ovarian cancer.

Journal Of Ovarian Research

Cheng, Xianliang X; Zhang, Lei L; Chen, Yajuan Y; Qing, Chen C

Publication Date: 2017-11-13

Variant appearance in text: HER2: H1047R

PubMed Link: 29132396

Variant Present in the following documents:

• Main text

View BVdb publication page

---

An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression.

Journal Of The National Cancer Institute

Schwarz, Luis J LJ; Hutchinson, Katherine E KE; Rexer, Brent N BN; Estrada, Mónica Valeria MV; Gonzalez Ericsson, Paula I PI; Sanders, Melinda E ME; Dugger, Teresa C TC; Formisano, Luigi L; Guerrero-Zotano, Angel A; Red-Brewer, Monica M; Young, Christian D CD; Lantto, Johan J; Pedersen, Mikkel W MW; Kragh, Michael M; Horak, Ivan D ID; Arteaga, Carlos L CL

Publication Date: 2017-11-01

Variant appearance in text: HER2: H1047R

PubMed Link: 29059433

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Predicting ligand-dependent tumors from multi-dimensional signaling features.

Npj Systems Biology And Applications

Hass, Helge H; Masson, Kristina K; Wohlgemuth, Sibylle S; Paragas, Violette V; Allen, John E JE; Sevecka, Mark M; Pace, Emily E; Timmer, Jens J; Stelling, Joerg J; MacBeath, Gavin G; Schoeberl, Birgit B; Raue, Andreas A

Publication Date: 2017

Variant appearance in text: HER2: H1047R

PubMed Link: 28944080

Variant Present in the following documents:

• Main text
• 41540_2017_Article_30.pdf

View BVdb publication page

---