ERBB2 c.3458G>A ;(p.R1153Q)

Variant ID: 17-37883987-G-A

NM_004448.2(ERBB2):c.3458G>A;(p.R1153Q)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Systematic assessment and optimizing algorithm of tumor mutational burden calculation and their implications in clinical decision-making.

Frontiers In Oncology
Sun, Daqiang D; Xu, Meilin M; Pan, Chaohu C; Tang, Hongzhen H; Wang, Peng P; Wu, Dongfang D; Luo, Haitao H
Publication Date: 2022

Variant appearance in text: ERBB2: 3458G>A
PubMed Link: 36425562
Variant Present in the following documents:
  • Table_3.xlsx, sheet 1
View BVdb publication page



Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria.

American Journal Of Human Genetics
Pejaver, Vikas V; Byrne, Alicia B AB; Feng, Bing-Jian BJ; Pagel, Kymberleigh A KA; Mooney, Sean D SD; Karchin, Rachel R; O'Donnell-Luria, Anne A; Harrison, Steven M SM; Tavtigian, Sean V SV; Greenblatt, Marc S MS; Biesecker, Leslie G LG; Radivojac, Predrag P; Brenner, Steven E SE; ,
Publication Date: 2022-12-01

Variant appearance in text: ERBB2: R1153Q; rs758365405
PubMed Link: 36413997
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer.

Npj Breast Cancer
Bortolini Silveira, Amanda A; Bidard, François-Clément FC; Tanguy, Marie-Laure ML; Girard, Elodie E; Trédan, Olivier O; Dubot, Coraline C; Jacot, William W; Goncalves, Anthony A; Debled, Marc M; Levy, Christelle C; Ferrero, Jean-Marc JM; Jouannaud, Christelle C; Rios, Maria M; Mouret-Reynier, Marie-Ange MA; Dalenc, Florence F; Hego, Caroline C; Rampanou, Aurore A; Albaud, Benoit B; Baulande, Sylvain S; Berger, Frédérique F; Lemonnier, Jérôme J; Renault, Shufang S; Desmoulins, Isabelle I; Proudhon, Charlotte C; Pierga, Jean-Yves JY
Publication Date: 2021-09-09

Variant appearance in text: ERBB2: 3458G>A; R1153Q
PubMed Link: 34504096
Variant Present in the following documents:
  • 41523_2021_319_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Genomic profile of advanced breast cancer in circulating tumour DNA.

Nature Communications
Kingston, Belinda B; Cutts, Rosalind J RJ; Bye, Hannah H; Beaney, Matthew M; Walsh-Crestani, Giselle G; Hrebien, Sarah S; Swift, Claire C; Kilburn, Lucy S LS; Kernaghan, Sarah S; Moretti, Laura L; Wilkinson, Katie K; Wardley, Andrew M AM; Macpherson, Iain R IR; Baird, Richard D RD; Roylance, Rebecca R; Reis-Filho, Jorge S JS; Hubank, Michael M; Faull, Iris I; Banks, Kimberly C KC; Lanman, Richard B RB; Garcia-Murillas, Isaac I; Bliss, Judith M JM; Ring, Alistair A; Turner, Nicholas C NC
Publication Date: 2021-04-23

Variant appearance in text: HER2: R1153Q
PubMed Link: 33893289
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pure high-grade papillary urothelial bladder cancer: a luminal-like subgroup with potential for targeted therapy.

Cellular Oncology (Dordrecht)
Schnitzler, Tician T; Ortiz-Brüchle, Nadina N; Schneider, Ursula U; Lurje, Isabella I; Guricova, Karolina K; Buchner, Alexander A; Schulz, Gerald Bastian GB; Heidenreich, Axel A; Gaisa, Nadine Therese NT; Knüchel, Ruth R; Garczyk, Stefan S
Publication Date: 2020-10

Variant appearance in text: ERBB2: 3458G>A; Arg1153Gln; rs758365405
PubMed Link: 32445084
Variant Present in the following documents:
  • 13402_2020_524_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



HER2 exon 27 mutations predict worse survival of breast cancer patients, especially in HER2-negative patients.

Cancer Medicine
Si, Pilei P; Chen, Tao T; Fang, Bin B; Yao, Jiabing J; Liu, Gaoxiu G; Chen, Haijun H; Zhai, Baoping B; Li, Wentao W
Publication Date: 2017-12

Variant appearance in text: HER2: R1153Q
PubMed Link: 29072371
Variant Present in the following documents:
  • Main text
  • CAM4-6-2832.pdf
View BVdb publication page



Genomic characterization of HER2-positive breast cancer and response to neoadjuvant trastuzumab and chemotherapy-results from the ACOSOG Z1041 (Alliance) trial.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Lesurf, R R; Griffith, O L OL; Griffith, M M; Hundal, J J; Trani, L L; Watson, M A MA; Aft, R R; Ellis, M J MJ; Ota, D D; Suman, V J VJ; Meric-Bernstam, F F; Leitch, A M AM; Boughey, J C JC; Unzeitig, G G; Buzdar, A U AU; Hunt, K K KK; Mardis, E R ER
Publication Date: 2017-05-01

Variant appearance in text: ERBB2: R1153Q
PubMed Link: 28453704
Variant Present in the following documents:
  • Main text
View BVdb publication page