Publications:

---

Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?

Frontiers In Pharmacology

Maslarinou, Anthi A; Manolopoulos, Vangelis G VG; Ragia, Georgia G

Publication Date: 2023

Variant appearance in text: rs1053004

PubMed Link: 37256234

Variant Present in the following documents:

• fphar-14-1184523.pdf

View BVdb publication page

---

Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo.

Ejhaem

Safa, Firas F; Rasmussen, Terri T; Lobelle-Rich, Patricia P; Collier, Stephanie S; Milligan, Nicholas N; Schmeig, John J; Schmid, Janet J; Wiewiorowski, Carol C; Totaro, Denise D; Brown, Theresa C TC; Satyavarapu, Ishwarya I; Badoo, Melody M; Ungerleider, Nathan N; Flemington, Erik K EK; Safah, Hana H; Saba, Nakhle S NS

Publication Date: 2022-11

Variant appearance in text: rs1053004

PubMed Link: 36467812

Variant Present in the following documents:

• JHA2-3-1326-s001.xlsx, sheet 1

View BVdb publication page

---

Pharmacogenetics Role of Genetic Variants in Immune-Related Factors: A Systematic Review Focusing on mCRC.

Pharmaceutics

Scarabel, Lucia L; Bignucolo, Alessia A; Toffoli, Giuseppe G; Cecchin, Erika E; De Mattia, Elena E

Publication Date: 2022-11-15

Variant appearance in text: rs1053004

PubMed Link: 36432658

Variant Present in the following documents:

• Main text
• pharmaceutics-14-02468.pdf

View BVdb publication page

---

Beneficial effects of mifepristone treatment in breast cancer patients selected by the progesterone receptor isoform ratio: Results from the MIPRA trial.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Elía, Andrés A; Saldain, Leo L; Vanzulli, Silvia I SI; Helguero, Luisa A LA; Lamb, Caroline A CA; Fabris, Victoria V; Pataccini, Gabriela G; Martínez-Vazquez, Paula P; Burruchaga, Javier J; Caillet-Bois, Ines I; Spengler, Eunice E; Acosta Haab, Gabriela G; Liguori, Marcos M; Castets, Alejandra A; Lovisi, Silvia S; Abascal, María F MF; Novaro, Virginia V; Sánchez, Jana J; Muñoz, Javier J; Belizán, Jose M JM; Abba, Martín C MC; Gass, Hugo H; Rojas, Paola P; Lanari, Claudia C

Publication Date: 2022-10-21

Variant appearance in text: rs1053004

PubMed Link: 36269797

Variant Present in the following documents:

• ccr-22-2060_supplementary_table_s5_suppts5.xlsx, sheet 1

View BVdb publication page

---

Tumor-Suppressive and Oncogenic Roles of microRNA-149-5p in Human Cancers.

International Journal Of Molecular Sciences

Shen, Yang Y; Zhao, Nan N; Zhao, Nan N; Hu, Xinyao X; He, Xiaoqin X; Xu, Yangtao Y; Chen, Jiayu J; Chen, Wenliang W; Liu, Xin X; Zhou, Zhuolin Z; Cao, Dedong D; Xu, Ximing X

Publication Date: 2022-09-16

Variant appearance in text: rs1053004

PubMed Link: 36142734

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Association of JAK/STAT genetic variants with cutaneous melanoma.

Frontiers In Oncology

Gomez, Gabriela Vilas Bôas GVB; Lourenço, Gustavo Jacob GJ; Monteiro, Lummy Maria Oliveira LMO; Rocha, Rafael Silva RS; Fernández, Kimberly Anne McGrail KAM; Recio, Juan Angel JA; Torricelli, Caroline C; Coser, Lilian Oliveira LO; Oliveira, Alexandre Leite Rodrigues ALR; Carron, Juliana J; Moraes, Aparecida Machado AM; Lima, Carmen Silvia Passos CSP

Publication Date: 2022

Variant appearance in text: rs1053004

PubMed Link: 35982955

Variant Present in the following documents:

• Main text
• fonc-12-943483.pdf
• DataSheet_1.pdf

View BVdb publication page

---

The use of pharmacogenetics to increase the safety of colorectal cancer patients treated with fluoropyrimidines.

Cancer Drug Resistance (Alhambra, Calif.)

De Mattia, Elena E; Roncato, Rossana R; Dalle Fratte, Chiara C; Ecca, Fabrizio F; Toffoli, Giuseppe G; Cecchin, Erika E

Publication Date: 2019

Variant appearance in text: rs1053004

PubMed Link: 35582139

Variant Present in the following documents:

• cdr-2-116.pdf

View BVdb publication page

---

Genetics and Functional Mechanisms of STAT3 Polymorphisms in Human Tuberculosis.

Frontiers In Cellular And Infection Microbiology

Wang, Feifei F; Huang, Guixian G; Shen, Ling L; Peng, Ying Y; Sha, Wei W; Chen, Zheng W ZW; Shen, Hongbo H

Publication Date: 2021

Variant appearance in text: rs1053004

PubMed Link: 34307193

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic Susceptibility to Acute Kidney Injury.

Journal Of Clinical Medicine

Ortega-Loubon, Christian C; Martínez-Paz, Pedro P; García-Morán, Emilio E; Tamayo-Velasco, Álvaro Á; López-Hernández, Francisco J FJ; Jorge-Monjas, Pablo P; Tamayo, Eduardo E

Publication Date: 2021-07-08

Variant appearance in text: rs1053004

PubMed Link: 34300206

Variant Present in the following documents:

• Main text
• jcm-10-03039.pdf

View BVdb publication page

---

STAT3 polymorphisms in North Africa and its implication in breast cancer.

Molecular Genetics & Genomic Medicine

Ziadi, Wafa W; Boussetta, Sami S; Elkamel, Sarra S; Pakstis, Andrew J AJ; Kidd, Kenneth K KK; Medimegh, Imen I; Ben Ammar Elgaaied, Amel A; Cherni, Lotfi L

Publication Date: 2021-08

Variant appearance in text: rs1053004

PubMed Link: 34251094

Variant Present in the following documents:

• Main text

View BVdb publication page

---

STAT3 polymorphisms in North Africa and its implication in breast cancer.

Molecular Genetics & Genomic Medicine

Ziadi, Wafa W; Boussetta, Sami S; Elkamel, Sarra S; Pakstis, Andrew J AJ; Kidd, Kenneth K KK; Medimegh, Imen I; Ben Ammar Elgaaied, Amel A; Cherni, Lotfi L

Publication Date: 2021-08

Variant appearance in text: rs1053004

PubMed Link: 34251094

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Multiomics dissection of molecular regulatory mechanisms underlying autoimmune-associated noncoding SNPs.

Jci Insight

Chen, Xiao-Feng XF; Guo, Ming-Rui MR; Duan, Yuan-Yuan YY; Jiang, Feng F; Wu, Hao H; Dong, Shan-Shan SS; Zhou, Xiao-Rong XR; Thynn, Hlaing Nwe HN; Liu, Cong-Cong CC; Zhang, Lin L; Guo, Yan Y; Yang, Tie-Lin TL

Publication Date: 2020-09-03

Variant appearance in text: rs1053004

PubMed Link: 32879140

Variant Present in the following documents:

• jciinsight-5-136477-s105.xlsx, sheet 5

View BVdb publication page

---

Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy.

Frontiers In Pharmacology

De Mattia, Elena E; Roncato, Rossana R; Palazzari, Elisa E; Toffoli, Giuseppe G; Cecchin, Erika E

Publication Date: 2020

Variant appearance in text: rs1053004

PubMed Link: 32625092

Variant Present in the following documents:

• fphar-11-00897.pdf

View BVdb publication page

---

Germline Polymorphisms in the Nuclear Receptors PXR and VDR as Novel Prognostic Markers in Metastatic Colorectal Cancer Patients Treated With FOLFIRI.

Frontiers In Oncology

De Mattia, Elena E; Polesel, Jerry J; Roncato, Rossana R; Labriet, Adrien A; Bignucolo, Alessia A; Dreussi, Eva E; Romanato, Loredana L; Guardascione, Michela M; Buonadonna, Angela A; D'Andrea, Mario M; Lévesque, Eric E; Jonker, Derek D; Couture, Félix F; Guillemette, Chantal C; Cecchin, Erika E; Toffoli, Giuseppe G

Publication Date: 2019

Variant appearance in text: rs1053004

PubMed Link: 31850208

Variant Present in the following documents:

• fonc-09-01312.pdf

View BVdb publication page

---

Polymorphisms of the TNF Gene and Three Susceptibility Loci Are Associated with Crohn's Disease and Perianal Fistula Crohn's Disease: A Study among the Han Population from South China.

Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research

Zhang, Min M; Wang, Xiaoyan X; Jiang, Xiaodong X; Yang, Xiangling X; Wen, Chuangyu C; Zhi, Min M; Gao, Xiang X; Hu, Pinjin P; Liu, Huanliang H

Publication Date: 2019-12-17

Variant appearance in text: rs1053004

PubMed Link: 31844038

Variant Present in the following documents:

• Main text

View BVdb publication page

---

PGG.SNV: understanding the evolutionary and medical implications of human single nucleotide variations in diverse populations.

Genome Biology

Zhang, Chao C; Gao, Yang Y; Ning, Zhilin Z; Lu, Yan Y; Zhang, Xiaoxi X; Liu, Jiaojiao J; Xie, Bo B; Xue, Zhe Z; Wang, Xiaoji X; Yuan, Kai K; Ge, Xueling X; Pan, Yuwen Y; Liu, Chang C; Tian, Lei L; Wang, Yuchen Y; Lu, Dongsheng D; Hoh, Boon-Peng BP; Xu, Shuhua S

Publication Date: 2019-10-22

Variant appearance in text: rs1053004

PubMed Link: 31640808

Variant Present in the following documents:

• 13059_2019_1838_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

---

Association between host TNF-α, TGF-β1, p53 polymorphisms, HBV X gene mutation, HBV viral load and the progression of HBV-associated chronic liver disease in Indonesian patients.

Biomedical Reports

Wungu, Citrawati Dyah Kencono CDK; Amin, Mochamad M; Ruslan, S Eriaty N SEN; Purwono, Priyo Budi PB; Kholili, Ulfa U; Maimunah, Ummi U; Setiawan, Poernomo Boedi PB; Lusida, Maria Inge MI; Soetjipto, Soetjipto S; Handajani, Retno R

Publication Date: 2019-10

Variant appearance in text: rs1053004

PubMed Link: 31565220

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Host Genetic Determinants of Hepatitis B Virus Infection.

Frontiers In Genetics

Zhang, Zhenhua Z; Wang, Changtai C; Liu, Zhongping Z; Zou, Guizhou G; Li, Jun J; Lu, Mengji M

Publication Date: 2019

Variant appearance in text: rs1053004

PubMed Link: 31475028

Variant Present in the following documents:

• Main text
• fgene-10-00696.pdf

View BVdb publication page

---

Association of SP1 rs1353058818 and STAT3 rs1053004 gene polymorphisms with human tongue squamous cell carcinoma.

Bioscience Reports

Lai, Heqing H; Xu, Guochao G; Meng, Haifeng H; Zhu, Haiying H

Publication Date: 2019-07-31

Variant appearance in text: rs1053004

PubMed Link: 31270251

Variant Present in the following documents:

• Main text

View BVdb publication page

---

STAT3 signaling pathway plays importantly genetic and functional roles in HCV infection.

Molecular Genetics & Genomic Medicine

Song, Yuzhu Y; Yang, Xianyao X; Shen, Yunsong Y; Wang, Yiqian Y; Xia, Xueshan X; Zhang, A-Mei AM

Publication Date: 2019-08

Variant appearance in text: rs1053004

PubMed Link: 31219249

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Association of STAT3 and STAT4 polymorphisms with susceptibility to chronic hepatitis B virus infection and risk of hepatocellular carcinoma: a meta-analysis.

Bioscience Reports

Shi, Han H; He, Hongyan H; Ojha, Suvash Chandra SC; Sun, Changfeng C; Fu, Juan J; Yan, Mao M; Deng, Cunliang C; Sheng, Yunjian Y

Publication Date: 2019-06-28

Variant appearance in text: rs1053004

PubMed Link: 31160486

Variant Present in the following documents:

• Main text
• bsr-39-bsr20190783.pdf

View BVdb publication page

---

Association between STAT3 rs1053004 polymorphism and cancer risk: a meta-analysis.

Molecular Biology Research Communications

Moazeni-Roodi, Abdolkarim A; Hashemi, Mohammad M

Publication Date: 2018-09

Variant appearance in text: rs1053004

PubMed Link: 30426029

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A Clinical-Genetic Score to Identify Surgically Resected Colorectal Cancer Patients Benefiting From an Adjuvant Fluoropyrimidine-Based Therapy.

Frontiers In Pharmacology

De Mattia, Elena E; Dreussi, Eva E; Montico, Marcella M; Gagno, Sara S; Zanusso, Chiara C; Quartuccio, Luca L; De Vita, Salvatore S; Guardascione, Michela M; Buonadonna, Angela A; D'Andrea, Mario M; Pella, Nicoletta N; Favaretto, Adolfo A; Mini, Enrico E; Nobili, Stefania S; Romanato, Loredana L; Cecchin, Erika E; Toffoli, Giuseppe G

Publication Date: 2018

Variant appearance in text: rs1053004

PubMed Link: 30337874

Variant Present in the following documents:

• fphar-09-01101.pdf

View BVdb publication page

---

Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients.

Frontiers In Pharmacology

De Mattia, Elena E; Cecchin, Erika E; Montico, Marcella M; Labriet, Adrien A; Guillemette, Chantal C; Dreussi, Eva E; Roncato, Rossana R; Bignucolo, Alessia A; Buonadonna, Angela A; D'Andrea, Mario M; Coppola, Luigi L; Lonardi, Sara S; Lévesque, Eric E; Jonker, Derek D; Couture, Félix F; Toffoli, Giuseppe G

Publication Date: 2018

Variant appearance in text: rs1053004

PubMed Link: 29706892

Variant Present in the following documents:

• Main text
• fphar-09-00367.pdf

View BVdb publication page

---

Association of polymorphism rs1053005 in STAT3 with chronic hepatitis B virus infection in Han Chinese population.

Bmc Medical Genetics

Li, Man M; Li, Fang F; Li, Na N; Sang, Jiao J; Fan, Xiude X; Deng, Huan H; Zhang, Xiaoge X; Han, Qunying Q; Lv, Yi Y; Liu, Zhengwen Z

Publication Date: 2018-04-02

Variant appearance in text: rs1053004

PubMed Link: 29609539

Variant Present in the following documents:

• Main text
• 12881_2018_Article_569.pdf

View BVdb publication page

---

Identification of EML4-ALK as an alternative fusion gene in epithelioid inflammatory myofibroblastic sarcoma.

Orphanet Journal Of Rare Diseases

Jiang, Quan Q; Tong, Han-Xing HX; Hou, Ying-Yong YY; Zhang, Yong Y; Li, Jing-Lei JL; Zhou, Yu-Hong YH; Xu, Jing J; Wang, Jiong-Yuan JY; Lu, Wei-Qi WQ

Publication Date: 2017-05-23

Variant appearance in text: rs1053004

PubMed Link: 28535796

Variant Present in the following documents:

• 13023_2017_647_MOESM1_ESM.xlsx, sheet 4

View BVdb publication page

---

Immune-related gene polymorphisms in pulmonary diseases.

Toxicology

Singh, Dhirendra P DP; Bagam, Prathyusha P; Sahoo, Malaya K MK; Batra, Sanjay S

Publication Date: 2017-05-15

Variant appearance in text: rs1053004

PubMed Link: 28366820

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A single nucleotide polymorphism in the 3'-UTR of STAT3 regulates its expression and reduces risk of pancreatic cancer in a Chinese population.

Oncotarget

Zhu, Beibei B; Zhu, Ying Y; Lou, Jiao J; Ke, Juntao J; Zhang, Yi Y; Li, Jiaoyuan J; Gong, Yajie Y; Yang, Yang Y; Tian, Jianbo J; Peng, Xiating X; Zou, Danyi D; Zhong, Rong R; Gong, Jing J; Chang, Jiang J; Li, Lu L; Miao, Xiaoping X

Publication Date: 2016-09-20

Variant appearance in text: rs1053004

PubMed Link: 27577070

Variant Present in the following documents:

• Main text
• oncotarget-07-62305.pdf

View BVdb publication page

---

Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population.

Oncotarget

Zhou, Fei F; Cheng, Lei L; Qiu, Li-Xin LX; Wang, Meng-Yun MY; Li, Jin J; Sun, Meng-Hong MH; Yang, Ya-Jun YJ; Wang, Jiu-Cun JC; Jin, Li L; Wang, Ya-Nong YN; Wei, Qing-Yi QY

Publication Date: 2016-05-10

Variant appearance in text: rs1053004

PubMed Link: 27049718

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Hepatitis B virus genotype, mutations, human leukocyte antigen polymorphisms and their interactions in hepatocellular carcinoma: a multi-centre case-control study.

Scientific Reports

Wen, Juan J; Song, Ci C; Jiang, Deke D; Jin, Tianbo T; Dai, Juncheng J; Zhu, Liguo L; An, Jiaze J; Liu, Yao Y; Ma, Shijie S; Qin, Na N; Liang, Cheng C; Chen, Jiaping J; Jiang, Yue Y; Yang, Linlin L; Liu, Jibin J; Liu, Li L; Geng, Tingting T; Chen, Chao C; Jiang, Jie J; Chen, Jianguo J; Zhu, Fengcai F; Zhu, Yefei Y; Yu, Long L; Shen, Hongbing H; Zhai, Xiangjun X; Xu, Jianfeng J; Hu, Zhibin Z

Publication Date: 2015-11-16

Variant appearance in text: rs1053004

PubMed Link: 26568165

Variant Present in the following documents:

• Main text
• srep16489.pdf

View BVdb publication page

---

Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans.

Gastroenterology

Huang, Chengrui C; Haritunians, Talin T; Okou, David T DT; Cutler, David J DJ; Zwick, Michael E ME; Taylor, Kent D KD; Datta, Lisa W LW; Maranville, Joseph C JC; Liu, Zhenqiu Z; Ellis, Shannon S; Chopra, Pankaj P; Alexander, Jonathan S JS; Baldassano, Robert N RN; Cross, Raymond K RK; Dassopoulos, Themistocles T; Dhere, Tanvi A TA; Duerr, Richard H RH; Hanson, John S JS; Hou, Jason K JK; Hussain, Sunny Z SZ; Isaacs, Kim L KL; Kachelries, Kelly E KE; Kader, Howard H; Kappelman, Michael D MD; Katz, Jeffrey J; Kellermayer, Richard R; Kirschner, Barbara S BS; Kuemmerle, John F JF; Kumar, Archana A; Kwon, John H JH; Lazarev, Mark M; Mannon, Peter P; Moulton, Dedrick E DE; Osuntokun, Bankole O BO; Patel, Ashish A; Rioux, John D JD; Rotter, Jerome I JI; Saeed, Shehzad S; Scherl, Ellen J EJ; Silverberg, Mark S MS; Silverman, Ann A; Targan, Stephan R SR; Valentine, John F JF; Wang, Ming-Hsi MH; Simpson, Claire L CL; Bridges, S Louis SL; Kimberly, Robert P RP; Rich, Stephen S SS; Cho, Judy H JH; Rienzo, Anna Di AD; Kao, Linda W H LWH; McGovern, Dermot P B DPB; Brant, Steven R SR; Kugathasan, Subra S

Publication Date: 2015-11

Variant appearance in text: rs1053004

PubMed Link: 26278503

Variant Present in the following documents:

• Main text

View BVdb publication page

---

STAT3 polymorphisms may predict an unfavorable response to first-line platinum-based therapy for women with advanced serous epithelial ovarian cancer.

International Journal Of Cancer

Permuth-Wey, Jennifer J; Fulp, William J WJ; Reid, Brett M BM; Chen, Zhihua Z; Georgeades, Christina C; Cheng, Jin Q JQ; Magliocco, Anthony A; Chen, Dung-Tsa DT; Lancaster, Johnathan M JM

Publication Date: 2016-02-01

Variant appearance in text: rs1053004

PubMed Link: 26264211

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.

Oncotarget

Keerthikumar, Shivakumar S; Gangoda, Lahiru L; Liem, Michael M; Fonseka, Pamali P; Atukorala, Ishara I; Ozcitti, Cemil C; Mechler, Adam A; Adda, Christopher G CG; Ang, Ching-Seng CS; Mathivanan, Suresh S

Publication Date: 2015-06-20

Variant appearance in text: rs1053004

PubMed Link: 25944692

Variant Present in the following documents:

• oncotarget-06-15375-s005.xlsx, sheet 2

View BVdb publication page

---

Analysis of IL-6, STAT3 and HSPA1L gene polymorphisms in anti-tuberculosis drug-induced hepatitis in a nested case-control study.

Plos One

Wang, Jing J; Chen, Ru R; Tang, Shaowen S; Lv, Xiaozhen X; Wu, Shanshan S; Zhang, Yuan Y; Xia, Yinyin Y; Gao, Pei P; Tu, Dehua D; Chen, Dafang D; Zhan, Siyan S

Publication Date: 2015

Variant appearance in text: rs1053004

PubMed Link: 25789467

Variant Present in the following documents:

• Main text
• pone.0118862.pdf

View BVdb publication page

---

Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA-microRNA regulatory network in nasopharyngeal carcinoma model systems.

Febs Open Bio

Szeto, Carol Ying-Ying CY; Lin, Chi Ho CH; Choi, Siu Chung SC; Yip, Timothy T C TT; Ngan, Roger Kai-Cheong RK; Tsao, George Sai-Wah GS; Li Lung, Maria M

Publication Date: 2014

Variant appearance in text: rs1053004

PubMed Link: 24490137

Variant Present in the following documents:

• mmc5.xlsx, sheet 2

View BVdb publication page

---

Targeted re-sequencing identified rs3106189 at the 5' UTR of TAPBP and rs1052918 at the 3' UTR of TCF3 to be associated with the overall survival of colorectal cancer patients.

Plos One

Shao, Jiaofang J; Lou, Xiaoyan X; Wang, Jun J; Zhang, Jing J; Chen, Chen C; Hua, Dasong D; Mo, Fan F; Han, Xu X; Zheng, Shu S; Lin, Biaoyang B

Publication Date: 2013

Variant appearance in text: rs1053004

PubMed Link: 23940558

Variant Present in the following documents:

• pone.0070307.s002.xlsx, sheet 1

View BVdb publication page

---

STAT3 single-nucleotide polymorphisms and STAT3 mutations associated with hyper-IgE syndrome are not responsible for increased serum IgE serum levels in asthma families.

European Journal Of Human Genetics : Ejhg

Wjst, Matthias M; Lichtner, Peter P; Meitinger, Thomas T; Grimbacher, Bodo B

Publication Date: 2009-03

Variant appearance in text: rs1053004

PubMed Link: 18841165

Variant Present in the following documents:

• Main text

View BVdb publication page

---