Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.
Nature Medicine
Johnson, Neil N; Li, Yu-Chen YC; Walton, Zandra E ZE; Cheng, Katherine A KA; Li, Danan D; Rodig, Scott J SJ; Moreau, Lisa A LA; Unitt, Christine C; Bronson, Roderick T RT; Thomas, Huw D HD; Newell, David R DR; D'Andrea, Alan D AD; Curtin, Nicola J NJ; Wong, Kwok-Kin KK; Shapiro, Geoffrey I GI
Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage.
Molecular Cell
Johnson, Neil N; Cai, Dongpo D; Kennedy, Richard D RD; Pathania, Shailja S; Arora, Mansi M; Li, Yu-Chen YC; D'Andrea, Alan D AD; Parvin, Jeffrey D JD; Shapiro, Geoffrey I GI