BRCA1-methylated triple negative breast cancers previously exposed to neoadjuvant chemotherapy form RAD51 foci and respond poorly to olaparib.
Frontiers In Oncology
Velazquez, Carolina C; Orhan, Esin E; Tabet, Imene I; Fenou, Lise L; Orsetti, Béatrice B; Adélaïde, José J; Guille, Arnaud A; Thézénas, Simon S; Crapez, Evelyne E; Colombo, Pierre-Emmanuel PE; Chaffanet, Max M; Birnbaum, Daniel D; Sardet, Claude C; Jacot, William W; Theillet, Charles C
Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Serra, Violeta V; Wang, Anderson T AT; Castroviejo-Bermejo, Marta M; Polanska, Urszula M UM; Palafox, Marta M; Herencia-Ropero, Andrea A; Jones, Gemma N GN; Lai, Zhongwu Z; Armenia, Joshua J; Michopoulos, Filippos F; Llop-Guevara, Alba A; Brough, Rachel R; Gulati, Aditi A; Pettitt, Stephen J SJ; Bulusu, Krishna C KC; Nikkilä, Jenni J; Wilson, Zena Z; Hughes, Adina A; Wijnhoven, Paul W G PWG; Ahmed, Ambar A; Bruna, Alejandra A; Gris-Oliver, Albert A; Guzman, Marta M; Rodríguez, Olga O; Grueso, Judit J; Arribas, Joaquin J; Cortés, Javier J; Saura, Cristina C; Lau, Alan A; Critchlow, Susan S; Dougherty, Brian B; Caldas, Carlos C; Mills, Gordon B GB; Barrett, J Carl JC; Forment, Josep V JV; Cadogan, Elaine E; Lord, Christopher J CJ; Cruz, Cristina C; Balmaña, Judith J; O'Connor, Mark J MJ
Molecular Evaluation of Endometrial Dedifferentiated Carcinoma, Endometrioid Carcinoma, Carcinosarcoma, and Serous Carcinoma Using a Custom-Made Small Cancer Panel.
Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxorubicin.
Hereditary Cancer In Clinical Practice
Gorodnova, Tatiana V TV; Sokolenko, Anna P AP; Kotiv, Khristina B KB; Sokolova, Tatiana N TN; Ivantsov, Alexandr O AO; Guseynov, Konstantin D KD; Nekrasova, Ekaterina A EA; Smirnova, Olga A OA; Berlev, Igor V IV; Imyanitov, Evgeny N EN
BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.
Bmc Cancer
Holstege, Henne H; Horlings, Hugo M HM; Velds, Arno A; Langerød, Anita A; Børresen-Dale, Anne-Lise AL; van de Vijver, Marc J MJ; Nederlof, Petra M PM; Jonkers, Jos J