Publications:

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High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer.

Breast Cancer (Tokyo, Japan)

Zhu, Liang L; Pan, Jia-Ni JN; Qian, Ziliang Z; Ye, Wei-Wu WW; Wang, Xiao-Jia XJ; Cao, Wen-Ming WM

Publication Date: 2022-01

Variant appearance in text: BRCA1: 223G>T; Glu75Ter

PubMed Link: 34403063

Variant Present in the following documents:

• Main text
• 12282_2021_Article_1286.pdf

View BVdb publication page

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High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer.

Breast Cancer (Tokyo, Japan)

Zhu, Liang L; Pan, Jia-Ni JN; Qian, Ziliang Z; Ye, Wei-Wu WW; Wang, Xiao-Jia XJ; Cao, Wen-Ming WM

Publication Date: 2021-08-17

Variant appearance in text: BRCA1: 223G>T; Glu75Ter

PubMed Link: 34403063

Variant Present in the following documents:

• Main text
• 12282_2021_Article_1286.pdf

View BVdb publication page

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Prediction of the functional impact of missense variants in BRCA1 and BRCA2 with BRCA-ML.

Npj Breast Cancer

Hart, Steven N SN; Polley, Eric C EC; Shimelis, Hermella H; Yadav, Siddhartha S; Couch, Fergus J FJ

Publication Date: 2020

Variant appearance in text: BRCA1: 223G>T; Glu75X

PubMed Link: 32377563

Variant Present in the following documents:

• 41523_2020_159_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Comprehensive mutation detection of BRCA1/2 genes reveals large genomic rearrangements contribute to hereditary breast and ovarian cancer in Chinese women.

Bmc Cancer

Cao, Wen-Ming WM; Zheng, Ya-Bing YB; Gao, Yun Y; Ding, Xiao-Wen XW; Sun, Yan Y; Huang, Yuan Y; Lou, Cai-Jin CJ; Pan, Zhi-Wen ZW; Peng, Guang G; Wang, Xiao-Jia XJ

Publication Date: 2019-06-07

Variant appearance in text: BRCA1: 223G>T; Glu75Ter

PubMed Link: 31174498

Variant Present in the following documents:

• Main text
• 12885_2019_Article_5765.pdf

View BVdb publication page

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Accurate classification of BRCA1 variants with saturation genome editing.

Nature

Findlay, Gregory M GM; Daza, Riza M RM; Martin, Beth B; Zhang, Melissa D MD; Leith, Anh P AP; Gasperini, Molly M; Janizek, Joseph D JD; Huang, Xingfan X; Starita, Lea M LM; Shendure, Jay J

Publication Date: 2018-10

Variant appearance in text: BRCA1: 223G>T; E75*

PubMed Link: 30209399

Variant Present in the following documents:

• NIHMS1501643-supplement-2.xlsx, sheet 1

View BVdb publication page

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The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.

Nature Communications

Inman, Gareth J GJ; Wang, Jun J; Nagano, Ai A; Alexandrov, Ludmil B LB; Purdie, Karin J KJ; Taylor, Richard G RG; Sherwood, Victoria V; Thomson, Jason J; Hogan, Sarah S; Spender, Lindsay C LC; South, Andrew P AP; Stratton, Michael M; Chelala, Claude C; Harwood, Catherine A CA; Proby, Charlotte M CM; Leigh, Irene M IM

Publication Date: 2018-09-10

Variant appearance in text: BRCA1: E75*

PubMed Link: 30202019

Variant Present in the following documents:

• 41467_2018_6027_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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