Body mass index interacts with a genetic-risk score for depression increasing the risk of the disease in high-susceptibility individuals.
Translational Psychiatry
Anguita-Ruiz, Augusto A; Zarza-Rebollo, Juan Antonio JA; Pérez-Gutiérrez, Ana M AM; Molina, Esther E; Gutiérrez, Blanca B; Bellón, Juan Ángel JÁ; Moreno-Peral, Patricia P; Conejo-Cerón, Sonia S; Aiarzagüena, Jose María JM; Ballesta-Rodríguez, M Isabel MI; Fernández, Anna A; Fernández-Alonso, Carmen C; Martín-Pérez, Carlos C; Montón-Franco, Carmen C; Rodríguez-Bayón, Antonina A; Torres-Martos, Álvaro Á; López-Isac, Elena E; Cervilla, Jorge J; Rivera, Margarita M
Association of Genetic Variants With Response to Anti-Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration.
Jama Ophthalmology
Lorés-Motta, Laura L; Riaz, Moeen M; Grunin, Michelle M; Corominas, Jordi J; van Asten, Freekje F; Pauper, Marc M; Leenders, Mathieu M; Richardson, Andrea J AJ; Muether, Philipp P; Cree, Angela J AJ; Griffiths, Helen L HL; Pham, Connie C; Belanger, Marie-Claude MC; Meester-Smoor, Magda A MA; Ali, Manir M; Heid, Iris M IM; Fritsche, Lars G LG; Chakravarthy, Usha U; Gale, Richard R; McKibbin, Martin M; Inglehearn, Chris F CF; Schlingemann, Reinier O RO; Omar, Amer A; Chen, John J; Koenekoop, Robert K RK; Fauser, Sascha S; Guymer, Robyn H RH; Hoyng, Carel B CB; de Jong, Eiko K EK; Lotery, Andrew J AJ; Mitchell, Paul P; den Hollander, Anneke I AI; Baird, Paul N PN; Chowers, Itay I
Influence of CRHR1 Polymorphisms and Childhood Abuse on Suicide Attempts in Affective Disorders: A GxE Approach.
Frontiers In Psychiatry
Ludwig, Birgit B; Kienesberger, Klemens K; Carlberg, Laura L; Swoboda, Patrick P; Bernegger, Alexandra A; Koller, Romina R; Wang, Qingzhong Q; Inaner, Michelle M; Zotter, Melanie M; Kapusta, Nestor D ND; Haslacher, Helmuth H; Aigner, Martin M; Kasper, Siegfried S; Schosser, Alexandra A
Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein.
The American Journal Of Psychiatry
O'Connell, Chloe P CP; Goldstein-Piekarski, Andrea N AN; Nemeroff, Charles B CB; Schatzberg, Alan F AF; Debattista, Charles C; Carrillo-Roa, Tania T; Binder, Elisabeth B EB; Dunlop, Boadie W BW; Craighead, W Edward WE; Mayberg, Helen S HS; Williams, Leanne M LM
Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation.
Journal Of Abnormal Psychology
Pagliaccio, David D; Luby, Joan L JL; Bogdan, Ryan R; Agrawal, Arpana A; Gaffrey, Michael S MS; Belden, Andrew C AC; Botteron, Kelly N KN; Harms, Michael P MP; Barch, Deanna M DM
Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.
Neuropsychiatric Disease And Treatment
Ching-López, Ana A; Cervilla, Jorge J; Rivera, Margarita M; Molina, Esther E; McKenney, Kathryn K; Ruiz-Perez, Isabel I; Rodríguez-Barranco, Miguel M; Gutiérrez, Blanca B
HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children.
Neuroimage
Pagliaccio, David D; Luby, Joan L JL; Bogdan, Ryan R; Agrawal, Arpana A; Gaffrey, Michael S MS; Belden, Andrew C AC; Botteron, Kelly N KN; Harms, Michael P MP; Barch, Deanna M DM
Relationship of cortisol levels and genetic polymorphisms to antidepressant response to placebo and fluoxetine in patients with major depressive disorder: a prospective study.
Bmc Psychiatry
Ventura-Juncá, Raúl R; Symon, Adriana A; López, Pamela P; Fiedler, Jenny L JL; Rojas, Graciela G; Heskia, Cristóbal C; Lara, Pamela P; Marín, Felipe F; Guajardo, Viviana V; Araya, A Verónica AV; Sasso, Jaime J; Herrera, Luisa L
Influence of genetic polymorphisms involved in the hypothalamic-pituitary-adrenal axis and their interactions with environmental factors on antidepressant response.
Stress-system genes and life stress predict cortisol levels and amygdala and hippocampal volumes in children.
Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Pagliaccio, David D; Luby, Joan L JL; Bogdan, Ryan R; Agrawal, Arpana A; Gaffrey, Michael S MS; Belden, Andrew C AC; Botteron, Kelly N KN; Harms, Michael P MP; Barch, Deanna M DM
Association of CRHR1 variants and posttraumatic stress symptoms in hurricane exposed adults.
Journal Of Anxiety Disorders
White, Simone S; Acierno, Ron R; Ruggiero, Kenneth J KJ; Koenen, Karestan C KC; Kilpatrick, Dean G DG; Galea, Sandro S; Gelernter, Joel J; Williamson, Vernell V; McMichael, Omari O; Vladimirov, Vladimir I VI; Amstadter, Ananda B AB
A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Kranzler, Henry R HR; Feinn, Richard R; Nelson, Elliot C EC; Covault, Jonathan J; Anton, Raymond F RF; Farrer, Lindsay L; Gelernter, Joel J
Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals.
Human Molecular Genetics
Briggs, Farren B S FB; Bartlett, Selena E SE; Goldstein, Benjamin A BA; Wang, Joanne J; McCauley, Jacob L JL; Zuvich, Rebecca L RL; De Jager, Philip L PL; Rioux, John D JD; Ivinson, Adrian J AJ; Compston, Alastair A; Hafler, David A DA; Hauser, Stephen L SL; Oksenberg, Jorge R JR; Sawcer, Stephen J SJ; Pericak-Vance, Margaret A MA; Haines, Jonathan L JL; , ; Barcellos, Lisa F LF
H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence.
Addiction Biology
Nelson, Elliot C EC; Agrawal, Arpana A; Pergadia, Michele L ML; Wang, Jen C JC; Whitfield, John B JB; Saccone, F Scott FS; Kern, Jason J; Grant, Julia D JD; Schrage, Andrew J AJ; Rice, John P JP; Montgomery, Grant W GW; Heath, Andrew C AC; Goate, Alison M AM; Martin, Nicholas G NG; Madden, Pamela A F PA