Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Genetic variation in CRHR1 is associated with short-term respiratory response to corticosteroids in preterm infants at risk for bronchopulmonary dysplasia.
Pediatric Research
Lewis, Tamorah T; Truog, William W; Norberg, Mike M; Ballard, Philip L PL; Torgerson, Dara D; ,
Bone mineral density in children with acute lymphoblastic leukemia.
Cancer
Inaba, Hiroto H; Cao, Xueyuan X; Han, Alice Q AQ; Panetta, John C JC; Ness, Kirsten K KK; Metzger, Monika L ML; Rubnitz, Jeffrey E JE; Ribeiro, Raul C RC; Sandlund, John T JT; Jeha, Sima S; Cheng, Cheng C; Pui, Ching-Hon CH; Relling, Mary V MV; Kaste, Sue C SC
Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein.
The American Journal Of Psychiatry
O'Connell, Chloe P CP; Goldstein-Piekarski, Andrea N AN; Nemeroff, Charles B CB; Schatzberg, Alan F AF; Debattista, Charles C; Carrillo-Roa, Tania T; Binder, Elisabeth B EB; Dunlop, Boadie W BW; Craighead, W Edward WE; Mayberg, Helen S HS; Williams, Leanne M LM
Differential effects of hydrocortisone, prednisone, and dexamethasone on hormonal and pharmacokinetic profiles: a pilot study in children with congenital adrenal hyperplasia.
International Journal Of Pediatric Endocrinology
Nebesio, Todd D TD; Renbarger, Jamie L JL; Nabhan, Zeina M ZM; Ross, Sydney E SE; Slaven, James E JE; Li, Lang L; Walvoord, Emily C EC; Eugster, Erica A EA
Amygdala functional connectivity, HPA axis genetic variation, and life stress in children and relations to anxiety and emotion regulation.
Journal Of Abnormal Psychology
Pagliaccio, David D; Luby, Joan L JL; Bogdan, Ryan R; Agrawal, Arpana A; Gaffrey, Michael S MS; Belden, Andrew C AC; Botteron, Kelly N KN; Harms, Michael P MP; Barch, Deanna M DM
Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression.
Neuropsychiatric Disease And Treatment
Ching-López, Ana A; Cervilla, Jorge J; Rivera, Margarita M; Molina, Esther E; McKenney, Kathryn K; Ruiz-Perez, Isabel I; Rodríguez-Barranco, Miguel M; Gutiérrez, Blanca B
HPA axis genetic variation, pubertal status, and sex interact to predict amygdala and hippocampus responses to negative emotional faces in school-age children.
Neuroimage
Pagliaccio, David D; Luby, Joan L JL; Bogdan, Ryan R; Agrawal, Arpana A; Gaffrey, Michael S MS; Belden, Andrew C AC; Botteron, Kelly N KN; Harms, Michael P MP; Barch, Deanna M DM
Relationship of cortisol levels and genetic polymorphisms to antidepressant response to placebo and fluoxetine in patients with major depressive disorder: a prospective study.
Bmc Psychiatry
Ventura-Juncá, Raúl R; Symon, Adriana A; López, Pamela P; Fiedler, Jenny L JL; Rojas, Graciela G; Heskia, Cristóbal C; Lara, Pamela P; Marín, Felipe F; Guajardo, Viviana V; Araya, A Verónica AV; Sasso, Jaime J; Herrera, Luisa L
Influence of genetic polymorphisms involved in the hypothalamic-pituitary-adrenal axis and their interactions with environmental factors on antidepressant response.
Stress-system genes and life stress predict cortisol levels and amygdala and hippocampal volumes in children.
Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Pagliaccio, David D; Luby, Joan L JL; Bogdan, Ryan R; Agrawal, Arpana A; Gaffrey, Michael S MS; Belden, Andrew C AC; Botteron, Kelly N KN; Harms, Michael P MP; Barch, Deanna M DM