Nonviral polymeric nanoparticles for gene therapy in pediatric CNS malignancies.
Nanomedicine : Nanotechnology, Biology, And Medicine
Choi, John J; Rui, Yuan Y; Kim, Jayoung J; Gorelick, Noah N; Wilson, David R DR; Kozielski, Kristen K; Mangraviti, Antonella A; Sankey, Eric E; Brem, Henry H; Tyler, Betty B; Green, Jordan J JJ; Jackson, Eric M EM
Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase.
Biochemistry
Daubner, S Colette SC; Avila, Audrey A; Bailey, Johnathan O JO; Barrera, Dimitrios D; Bermudez, Jaclyn Y JY; Giles, David H DH; Khan, Crystal A CA; Shaheen, Noel N; Thompson, Janie Womac JW; Vasquez, Jessica J; Oxley, Susan P SP; Fitzpatrick, Paul F PF