Genome-wide association study of medication-use and associated disease in the UK Biobank.
Nature Communications
Wu, Yeda Y; Byrne, Enda M EM; Zheng, Zhili Z; Kemper, Kathryn E KE; Yengo, Loic L; Mallett, Andrew J AJ; Yang, Jian J; Visscher, Peter M PM; Wray, Naomi R NR
To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes.
Frontiers In Genetics
Wallace, Amelia D AD; Wendt, George A GA; Barcellos, Lisa F LF; de Smith, Adam J AJ; Walsh, Kyle M KM; Metayer, Catherine C; Costello, Joseph F JF; Wiemels, Joseph L JL; Francis, Stephen S SS
Large-scale identification of clinical and genetic predictors of motor progression in patients with newly diagnosed Parkinson's disease: a longitudinal cohort study and validation.
The Lancet. Neurology
Latourelle, Jeanne C JC; Beste, Michael T MT; Hadzi, Tiffany C TC; Miller, Robert E RE; Oppenheim, Jacob N JN; Valko, Matthew P MP; Wuest, Diane M DM; Church, Bruce W BW; Khalil, Iya G IG; Hayete, Boris B; Venuto, Charles S CS
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases.
Jama Neurology
Witoelar, Aree A; Jansen, Iris E IE; Wang, Yunpeng Y; Desikan, Rahul S RS; Gibbs, J Raphael JR; Blauwendraat, Cornelis C; Thompson, Wesley K WK; Hernandez, Dena G DG; Djurovic, Srdjan S; Schork, Andrew J AJ; Bettella, Francesco F; Ellinghaus, David D; Franke, Andre A; Lie, Benedicte A BA; McEvoy, Linda K LK; Karlsen, Tom H TH; Lesage, Suzanne S; Morris, Huw R HR; Brice, Alexis A; Wood, Nicholas W NW; Heutink, Peter P; Hardy, John J; Singleton, Andrew B AB; Dale, Anders M AM; Gasser, Thomas T; Andreassen, Ole A OA; Sharma, Manu M; ,
Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci.
American Journal Of Epidemiology
Clyde, Merlise A MA; Palmieri Weber, Rachel R; Iversen, Edwin S ES; Poole, Elizabeth M EM; Doherty, Jennifer A JA; Goodman, Marc T MT; Ness, Roberta B RB; Risch, Harvey A HA; Rossing, Mary Anne MA; Terry, Kathryn L KL; Wentzensen, Nicolas N; Whittemore, Alice S AS; Anton-Culver, Hoda H; Bandera, Elisa V EV; Berchuck, Andrew A; Carney, Michael E ME; Cramer, Daniel W DW; Cunningham, Julie M JM; Cushing-Haugen, Kara L KL; Edwards, Robert P RP; Fridley, Brooke L BL; Goode, Ellen L EL; Lurie, Galina G; McGuire, Valerie V; Modugno, Francesmary F; Moysich, Kirsten B KB; Olson, Sara H SH; Pearce, Celeste Leigh CL; Pike, Malcolm C MC; Rothstein, Joseph H JH; Sellers, Thomas A TA; Sieh, Weiva W; Stram, Daniel D; Thompson, Pamela J PJ; Vierkant, Robert A RA; Wicklund, Kristine G KG; Wu, Anna H AH; Ziogas, Argyrios A; Tworoger, Shelley S SS; Schildkraut, Joellen M JM; ,
A Highly Polymorphic Copy Number Variant in the NSF Gene is Associated with Cocaine Dependence.
Scientific Reports
Cabana-Domínguez, Judit J; Roncero, Carlos C; Grau-López, Lara L; Rodríguez-Cintas, Laia L; Barral, Carmen C; Abad, Alfonso C AC; Erikson, Galina G; Wineinger, Nathan E NE; Torrico, Bàrbara B; Arenas, Concepció C; Casas, Miquel M; Ribasés, Marta M; Cormand, Bru B; Fernàndez-Castillo, Noèlia N
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci.
Human Molecular Genetics
Coetzee, Simon G SG; Shen, Howard C HC; Hazelett, Dennis J DJ; Lawrenson, Kate K; Kuchenbaecker, Karoline K; Tyrer, Jonathan J; Rhie, Suhn K SK; Levanon, Keren K; Karst, Alison A; Drapkin, Ronny R; Ramus, Susan J SJ; , ; Couch, Fergus J FJ; Offit, Kenneth K; Chenevix-Trench, Georgia G; Monteiro, Alvaro N A AN; Antoniou, Antonis A; Freedman, Matthew M; Coetzee, Gerhard A GA; Pharoah, Paul D P PD; Noushmehr, Houtan H; Gayther, Simon A SA; ,
Identification of six new susceptibility loci for invasive epithelial ovarian cancer.
Nature Genetics
Kuchenbaecker, Karoline B KB; Ramus, Susan J SJ; Tyrer, Jonathan J; Lee, Andrew A; Shen, Howard C HC; Beesley, Jonathan J; Lawrenson, Kate K; McGuffog, Lesley L; Healey, Sue S; Lee, Janet M JM; Spindler, Tassja J TJ; Lin, Yvonne G YG; Pejovic, Tanja T; Bean, Yukie Y; Li, Qiyuan Q; Coetzee, Simon S; Hazelett, Dennis D; Miron, Alexander A; Southey, Melissa M; Terry, Mary Beth MB; Goldgar, David E DE; Buys, Saundra S SS; Janavicius, Ramunas R; Dorfling, Cecilia M CM; van Rensburg, Elizabeth J EJ; Neuhausen, Susan L SL; Ding, Yuan Chun YC; Hansen, Thomas V O TV; Jønson, Lars L; Gerdes, Anne-Marie AM; Ejlertsen, Bent B; Barrowdale, Daniel D; Dennis, Joe J; Benitez, Javier J; Osorio, Ana A; Garcia, Maria Jose MJ; Komenaka, Ian I; Weitzel, Jeffrey N JN; Ganschow, Pamela P; Peterlongo, Paolo P; Bernard, Loris L; Viel, Alessandra A; Bonanni, Bernardo B; Peissel, Bernard B; Manoukian, Siranoush S; Radice, Paolo P; Papi, Laura L; Ottini, Laura L; Fostira, Florentia F; Konstantopoulou, Irene I; Garber, Judy J; Frost, Debra D; Perkins, Jo J; Platte, Radka R; Ellis, Steve S; , ; Godwin, Andrew K AK; Schmutzler, Rita Katharina RK; Meindl, Alfons A; Engel, Christoph C; Sutter, Christian C; Sinilnikova, Olga M OM; , ; Damiola, Francesca F; Mazoyer, Sylvie S; Stoppa-Lyonnet, Dominique D; Claes, Kathleen K; De Leeneer, Kim K; Kirk, Judy J; Rodriguez, Gustavo C GC; Piedmonte, Marion M; O'Malley, David M DM; de la Hoya, Miguel M; Caldes, Trinidad T; Aittomäki, Kristiina K; Nevanlinna, Heli H; Collée, J Margriet JM; Rookus, Matti A MA; Oosterwijk, Jan C JC; , ; Tihomirova, Laima L; Tung, Nadine N; Hamann, Ute U; Isaccs, Claudine C; Tischkowitz, Marc M; Imyanitov, Evgeny N EN; Caligo, Maria A MA; Campbell, Ian G IG; Hogervorst, Frans B L FB; , ; Olah, Edith E; Diez, Orland O; Blanco, Ignacio I; Brunet, Joan J; Lazaro, Conxi C; Pujana, Miquel Angel MA; Jakubowska, Anna A; Gronwald, Jacek J; Lubinski, Jan J; Sukiennicki, Grzegorz G; Barkardottir, Rosa B RB; Plante, Marie M; Simard, Jacques J; Soucy, Penny P; Montagna, Marco M; Tognazzo, Silvia S; Teixeira, Manuel R MR; , ; Pankratz, Vernon S VS; Wang, Xianshu X; Lindor, Noralane N; Szabo, Csilla I CI; Kauff, Noah N; Vijai, Joseph J; Aghajanian, Carol A CA; Pfeiler, Georg G; Berger, Andreas A; Singer, Christian F CF; Tea, Muy-Kheng MK; Phelan, Catherine M CM; Greene, Mark H MH; Mai, Phuong L PL; Rennert, Gad G; Mulligan, Anna Marie AM; Tchatchou, Sandrine S; Andrulis, Irene L IL; Glendon, Gord G; Toland, Amanda Ewart AE; Jensen, Uffe Birk UB; Kruse, Torben A TA; Thomassen, Mads M; Bojesen, Anders A; Zidan, Jamal J; Friedman, Eitan E; Laitman, Yael Y; Soller, Maria M; Liljegren, Annelie A; Arver, Brita B; Einbeigi, Zakaria Z; Stenmark-Askmalm, Marie M; Olopade, Olufunmilayo I OI; Nussbaum, Robert L RL; Rebbeck, Timothy R TR; Nathanson, Katherine L KL; Domchek, Susan M SM; Lu, Karen H KH; Karlan, Beth Y BY; Walsh, Christine C; Lester, Jenny J; , ; , ; Hein, Alexander A; Ekici, Arif B AB; Beckmann, Matthias W MW; Fasching, Peter A PA; Lambrechts, Diether D; Van Nieuwenhuysen, Els E; Vergote, Ignace I; Lambrechts, Sandrina S; Dicks, Ed E; Doherty, Jennifer A JA; Wicklund, Kristine G KG; Rossing, Mary Anne MA; Rudolph, Anja A; Chang-Claude, Jenny J; Wang-Gohrke, Shan S; Eilber, Ursula U; Moysich, Kirsten B KB; Odunsi, Kunle K; Sucheston, Lara L; Lele, Shashi S; Wilkens, Lynne R LR; Goodman, Marc T MT; Thompson, Pamela J PJ; Shvetsov, Yurii B YB; Runnebaum, Ingo B IB; Dürst, Matthias M; Hillemanns, Peter P; Dörk, Thilo T; Antonenkova, Natalia N; Bogdanova, Natalia N; Leminen, Arto A; Pelttari, Liisa M LM; Butzow, Ralf R; Modugno, Francesmary F; Kelley, Joseph L JL; Edwards, Robert P RP; Ness, Roberta B RB; du Bois, Andreas A; Heitz, Florian F; Schwaab, Ira I; Harter, Philipp P; Matsuo, Keitaro K; Hosono, Satoyo S; Orsulic, Sandra S; Jensen, Allan A; Kjaer, Susanne Kruger SK; Hogdall, Estrid E; Hasmad, Hanis Nazihah HN; Azmi, Mat Adenan Noor MA; Teo, Soo-Hwang SH; Woo, Yin-Ling YL; Fridley, Brooke L BL; Goode, Ellen L EL; Cunningham, Julie M JM; Vierkant, Robert A RA; Bruinsma, Fiona F; Giles, Graham G GG; Liang, Dong D; Hildebrandt, Michelle A T MA; Wu, Xifeng X; Levine, Douglas A DA; Bisogna, Maria M; Berchuck, Andrew A; Iversen, Edwin S ES; Schildkraut, Joellen M JM; Concannon, Patrick P; Weber, Rachel Palmieri RP; Cramer, Daniel W DW; Terry, Kathryn L KL; Poole, Elizabeth M EM; Tworoger, Shelley S SS; Bandera, Elisa V EV; Orlow, Irene I; Olson, Sara H SH; Krakstad, Camilla C; Salvesen, Helga B HB; Tangen, Ingvild L IL; Bjorge, Line L; van Altena, Anne M AM; Aben, Katja K H KK; Kiemeney, Lambertus A LA; Massuger, Leon F A G LF; Kellar, Melissa M; Brooks-Wilson, Angela A; Kelemen, Linda E LE; Cook, Linda S LS; Le, Nhu D ND; Cybulski, Cezary C; Yang, Hannah H; Lissowska, Jolanta J; Brinton, Louise A LA; Wentzensen, Nicolas N; Hogdall, Claus C; Lundvall, Lene L; Nedergaard, Lotte L; Baker, Helen H; Song, Honglin H; Eccles, Diana D; McNeish, Ian I; Paul, James J; Carty, Karen K; Siddiqui, Nadeem N; Glasspool, Rosalind R; Whittemore, Alice S AS; Rothstein, Joseph H JH; McGuire, Valerie V; Sieh, Weiva W; Ji, Bu-Tian BT; Zheng, Wei W; Shu, Xiao-Ou XO; Gao, Yu-Tang YT; Rosen, Barry B; Risch, Harvey A HA; McLaughlin, John R JR; Narod, Steven A SA; Monteiro, Alvaro N AN; Chen, Ann A; Lin, Hui-Yi HY; Permuth-Wey, Jenny J; Sellers, Thomas A TA; Tsai, Ya-Yu YY; Chen, Zhihua Z; Ziogas, Argyrios A; Anton-Culver, Hoda H; Gentry-Maharaj, Aleksandra A; Menon, Usha U; Harrington, Patricia P; Lee, Alice W AW; Wu, Anna H AH; Pearce, Celeste L CL; Coetzee, Gerry G; Pike, Malcolm C MC; Dansonka-Mieszkowska, Agnieszka A; Timorek, Agnieszka A; Rzepecka, Iwona K IK; Kupryjanczyk, Jolanta J; Freedman, Matt M; Noushmehr, Houtan H; Easton, Douglas F DF; Offit, Kenneth K; Couch, Fergus J FJ; Gayther, Simon S; Pharoah, Paul P PP; Antoniou, Antonis C AC; Chenevix-Trench, Georgia G; ,
Increased Rate of Sporadic and Recurrent Rare Genic Copy Number Variants in Parkinson's Disease Among Ashkenazi Jews.
Molecular Genetics & Genomic Medicine
Liu, X X; Cheng, R R; Ye, X X; Verbitsky, M M; Kisselev, S S; Mejia-Santana, H H; Louis, Ed E; Cote, Lj L; Andrews, H H; Waters, C C; Ford, B B; Fahn, S S; Marder, K K; Lee, Jh J; Clark, Ln L
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
Plos Genetics
Couch, Fergus J FJ; Wang, Xianshu X; McGuffog, Lesley L; Lee, Andrew A; Olswold, Curtis C; Kuchenbaecker, Karoline B KB; Soucy, Penny P; Fredericksen, Zachary Z; Barrowdale, Daniel D; Dennis, Joe J; Gaudet, Mia M MM; Dicks, Ed E; Kosel, Matthew M; Healey, Sue S; Sinilnikova, Olga M OM; Lee, Adam A; Bacot, François F; Vincent, Daniel D; Hogervorst, Frans B L FB; Peock, Susan S; Stoppa-Lyonnet, Dominique D; Jakubowska, Anna A; , ; Radice, Paolo P; Schmutzler, Rita Katharina RK; , ; Domchek, Susan M SM; Piedmonte, Marion M; Singer, Christian F CF; Friedman, Eitan E; Thomassen, Mads M; , ; Hansen, Thomas V O TV; Neuhausen, Susan L SL; Szabo, Csilla I CI; Blanco, Ignacio I; Greene, Mark H MH; Karlan, Beth Y BY; Garber, Judy J; Phelan, Catherine M CM; Weitzel, Jeffrey N JN; Montagna, Marco M; Olah, Edith E; Andrulis, Irene L IL; Godwin, Andrew K AK; Yannoukakos, Drakoulis D; Goldgar, David E DE; Caldes, Trinidad T; Nevanlinna, Heli H; Osorio, Ana A; Terry, Mary Beth MB; Daly, Mary B MB; van Rensburg, Elizabeth J EJ; Hamann, Ute U; Ramus, Susan J SJ; Toland, Amanda Ewart AE; Caligo, Maria A MA; Olopade, Olufunmilayo I OI; Tung, Nadine N; Claes, Kathleen K; Beattie, Mary S MS; Southey, Melissa C MC; Imyanitov, Evgeny N EN; Tischkowitz, Marc M; Janavicius, Ramunas R; John, Esther M EM; Kwong, Ava A; Diez, Orland O; Balmaña, Judith J; Barkardottir, Rosa B RB; Arun, Banu K BK; Rennert, Gad G; Teo, Soo-Hwang SH; Ganz, Patricia A PA; Campbell, Ian I; van der Hout, Annemarie H AH; van Deurzen, Carolien H M CH; Seynaeve, Caroline C; Gómez Garcia, Encarna B EB; van Leeuwen, Flora E FE; Meijers-Heijboer, Hanne E J HE; Gille, Johannes J P JJ; Ausems, Margreet G E M MG; Blok, Marinus J MJ; Ligtenberg, Marjolijn J L MJ; Rookus, Matti A MA; Devilee, Peter P; Verhoef, Senno S; van Os, Theo A M TA; Wijnen, Juul T JT; , ; , ; Frost, Debra D; Ellis, Steve S; Fineberg, Elena E; Platte, Radka R; Evans, D Gareth DG; Izatt, Louise L; Eeles, Rosalind A RA; Adlard, Julian J; Eccles, Diana M DM; Cook, Jackie J; Brewer, Carole C; Douglas, Fiona F; Hodgson, Shirley S; Morrison, Patrick J PJ; Side, Lucy E LE; Donaldson, Alan A; Houghton, Catherine C; Rogers, Mark T MT; Dorkins, Huw H; Eason, Jacqueline J; Gregory, Helen H; McCann, Emma E; Murray, Alex A; Calender, Alain A; Hardouin, Agnès A; Berthet, Pascaline P; Delnatte, Capucine C; Nogues, Catherine C; Lasset, Christine C; Houdayer, Claude C; Leroux, Dominique D; Rouleau, Etienne E; Prieur, Fabienne F; Damiola, Francesca F; Sobol, Hagay H; Coupier, Isabelle I; Venat-Bouvet, Laurence L; Castera, Laurent L; Gauthier-Villars, Marion M; Léoné, Mélanie M; Pujol, Pascal P; Mazoyer, Sylvie S; Bignon, Yves-Jean YJ; , ; Złowocka-Perłowska, Elżbieta E; Gronwald, Jacek J; Lubinski, Jan J; Durda, Katarzyna K; Jaworska, Katarzyna K; Huzarski, Tomasz T; Spurdle, Amanda B AB; Viel, Alessandra A; Peissel, Bernard B; Bonanni, Bernardo B; Melloni, Giulia G; Ottini, Laura L; Papi, Laura L; Varesco, Liliana L; Tibiletti, Maria Grazia MG; Peterlongo, Paolo P; Volorio, Sara S; Manoukian, Siranoush S; Pensotti, Valeria V; Arnold, Norbert N; Engel, Christoph C; Deissler, Helmut H; Gadzicki, Dorothea D; Gehrig, Andrea A; Kast, Karin K; Rhiem, Kerstin K; Meindl, Alfons A; Niederacher, Dieter D; Ditsch, Nina N; Plendl, Hansjoerg H; Preisler-Adams, Sabine S; Engert, Stefanie S; Sutter, Christian C; Varon-Mateeva, Raymonda R; Wappenschmidt, Barbara B; Weber, Bernhard H F BH; Arver, Brita B; Stenmark-Askmalm, Marie M; Loman, Niklas N; Rosenquist, Richard R; Einbeigi, Zakaria Z; Nathanson, Katherine L KL; Rebbeck, Timothy R TR; Blank, Stephanie V SV; Cohn, David E DE; Rodriguez, Gustavo C GC; Small, Laurie L; Friedlander, Michael M; Bae-Jump, Victoria L VL; Fink-Retter, Anneliese A; Rappaport, Christine C; Gschwantler-Kaulich, Daphne D; Pfeiler, Georg G; Tea, Muy-Kheng MK; Lindor, Noralane M NM; Kaufman, Bella B; Shimon Paluch, Shani S; Laitman, Yael Y; Skytte, Anne-Bine AB; Gerdes, Anne-Marie AM; Pedersen, Inge Sokilde IS; Moeller, Sanne Traasdahl ST; Kruse, Torben A TA; Jensen, Uffe Birk UB; Vijai, Joseph J; Sarrel, Kara K; Robson, Mark M; Kauff, Noah N; Mulligan, Anna Marie AM; Glendon, Gord G; Ozcelik, Hilmi H; Ejlertsen, Bent B; Nielsen, Finn C FC; Jønson, Lars L; Andersen, Mette K MK; Ding, Yuan Chun YC; Steele, Linda L; Foretova, Lenka L; Teulé, Alex A; Lazaro, Conxi C; Brunet, Joan J; Pujana, Miquel Angel MA; Mai, Phuong L PL; Loud, Jennifer T JT; Walsh, Christine C; Lester, Jenny J; Orsulic, Sandra S; Narod, Steven A SA; Herzog, Josef J; Sand, Sharon R SR; Tognazzo, Silvia S; Agata, Simona S; Vaszko, Tibor T; Weaver, Joellen J; Stavropoulou, Alexandra V AV; Buys, Saundra S SS; Romero, Atocha A; de la Hoya, Miguel M; Aittomäki, Kristiina K; Muranen, Taru A TA; Duran, Mercedes M; Chung, Wendy K WK; Lasa, Adriana A; Dorfling, Cecilia M CM; Miron, Alexander A; , ; Benitez, Javier J; Senter, Leigha L; Huo, Dezheng D; Chan, Salina B SB; Sokolenko, Anna P AP; Chiquette, Jocelyne J; Tihomirova, Laima L; Friebel, Tara M TM; Agnarsson, Bjarni A BA; Lu, Karen H KH; Lejbkowicz, Flavio F; James, Paul A PA; Hall, Per P; Dunning, Alison M AM; Tessier, Daniel D; Cunningham, Julie J; Slager, Susan L SL; Wang, Chen C; Hart, Steven S; Stevens, Kristen K; Simard, Jacques J; Pastinen, Tomi T; Pankratz, Vernon S VS; Offit, Kenneth K; Easton, Douglas F DF; Chenevix-Trench, Georgia G; Antoniou, Antonis C AC; ,
Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.
Bmc Medical Genetics
Liu, Xinmin X; Cheng, Rong R; Verbitsky, Miguel M; Kisselev, Sergey S; Browne, Andrew A; Mejia-Sanatana, Helen H; Louis, Elan D ED; Cote, Lucien J LJ; Andrews, Howard H; Waters, Cheryl C; Ford, Blair B; Frucht, Steven S; Fahn, Stanley S; Marder, Karen K; Clark, Lorraine N LN; Lee, Joseph H JH