Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions.
Npj Parkinson'S Disease
Cukier, Holly N HN; Kim, Hyunjin H; Griswold, Anthony J AJ; Codreanu, Simona G SG; Prince, Lisa M LM; Sherrod, Stacy D SD; McLean, John A JA; Dykxhoorn, Derek M DM; Ess, Kevin C KC; Hedera, Peter P; Bowman, Aaron B AB; Neely, M Diana MD
GWAS of stool frequency provides insights into gastrointestinal motility and irritable bowel syndrome.
Cell Genomics
Bonfiglio, Ferdinando F; Liu, Xingrong X; Smillie, Christopher C; Pandit, Anita A; Kurilshikov, Alexander A; Bacigalupe, Rodrigo R; Zheng, Tenghao T; Nim, Hieu H; Garcia-Etxebarria, Koldo K; Bujanda, Luis L; Andreasson, Anna A; Agreus, Lars L; Walter, Susanna S; Abecasis, Gonçalo G; Eijsbouts, Chris C; Jostins, Luke L; Parkes, Miles M; Hughes, David A DA; Timpson, Nicholas N; Raes, Jeroen J; Franke, Andre A; Kennedy, Nicholas A NA; Regev, Aviv A; Zhernakova, Alexandra A; Simren, Magnus M; Camilleri, Michael M; D'Amato, Mauro M
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Publication Date: 2021-01-08
Variant appearance in text: NSF: 2106G>A; K702K; rs199533
Screening non-MAPT genes of the Chr17q21 H1 haplotype in Parkinson's disease.
Parkinsonism & Related Disorders
Soto-Beasley, Alexandra I AI; Walton, Ronald L RL; Valentino, Rebecca R RR; Hook, Paul W PW; Labbé, Catherine C; Heckman, Michael G MG; Johnson, Patrick W PW; Goff, Loyal A LA; Uitti, Ryan J RJ; McLean, Pamela J PJ; Springer, Wolfdieter W; McCallion, Andrew S AS; Wszolek, Zbigniew K ZK; Ross, Owen A OA
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities.
Nature Communications
Nichols, Caitlin A CA; Gibson, William J WJ; Brown, Meredith S MS; Kosmicki, Jack A JA; Busanovich, John P JP; Wei, Hope H; Urbanski, Laura M LM; Curimjee, Naomi N; Berger, Ashton C AC; Gao, Galen F GF; Cherniack, Andrew D AD; Dhe-Paganon, Sirano S; Paolella, Brenton R BR; Beroukhim, Rameen R
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
Jama Neurology
Ma, Yiyi Y; Jun, Gyungah R GR; Zhang, Xiaoling X; Chung, Jaeyoon J; Naj, Adam C AC; Chen, Yuning Y; Bellenguez, Celine C; Hamilton-Nelson, Kara K; Martin, Eden R ER; Kunkle, Brian W BW; Bis, Joshua C JC; Debette, Stéphanie S; DeStefano, Anita L AL; Fornage, Myriam M; Nicolas, Gaël G; van Duijn, Cornelia C; Bennett, David A DA; De Jager, Philip L PL; Mayeux, Richard R; Haines, Jonathan L JL; Pericak-Vance, Margaret A MA; Seshadri, Sudha S; Lambert, Jean-Charles JC; Schellenberg, Gerard D GD; Lunetta, Kathryn L KL; Farrer, Lindsay A LA; ,
Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP.
Translational Psychiatry
Jiang, Shan S; Wen, Natalie N; Li, Zeran Z; Dube, Umber U; Del Aguila, Jorge J; Budde, John J; Martinez, Rita R; Hsu, Simon S; Fernandez, Maria V MV; Cairns, Nigel J NJ; , ; , ; Harari, Oscar O; Cruchaga, Carlos C; Karch, Celeste M CM
To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes.
Frontiers In Genetics
Wallace, Amelia D AD; Wendt, George A GA; Barcellos, Lisa F LF; de Smith, Adam J AJ; Walsh, Kyle M KM; Metayer, Catherine C; Costello, Joseph F JF; Wiemels, Joseph L JL; Francis, Stephen S SS
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Molecular Psychiatry
Bis, Joshua C JC; Jian, Xueqiu X; Kunkle, Brian W BW; Chen, Yuning Y; Hamilton-Nelson, Kara L KL; Bush, William S WS; Salerno, William J WJ; Lancour, Daniel D; Ma, Yiyi Y; Renton, Alan E AE; Marcora, Edoardo E; Farrell, John J JJ; Zhao, Yi Y; Qu, Liming L; Ahmad, Shahzad S; Amin, Najaf N; Amouyel, Philippe P; Beecham, Gary W GW; Below, Jennifer E JE; Campion, Dominique D; Cantwell, Laura L; Charbonnier, Camille C; Chung, Jaeyoon J; Crane, Paul K PK; Cruchaga, Carlos C; Cupples, L Adrienne LA; Dartigues, Jean-François JF; Debette, Stéphanie S; Deleuze, Jean-François JF; Fulton, Lucinda L; Gabriel, Stacey B SB; Genin, Emmanuelle E; Gibbs, Richard A RA; Goate, Alison A; Grenier-Boley, Benjamin B; Gupta, Namrata N; Haines, Jonathan L JL; Havulinna, Aki S AS; Helisalmi, Seppo S; Hiltunen, Mikko M; Howrigan, Daniel P DP; Ikram, M Arfan MA; Kaprio, Jaakko J; Konrad, Jan J; Kuzma, Amanda A; Lander, Eric S ES; Lathrop, Mark M; Lehtimäki, Terho T; Lin, Honghuang H; Mattila, Kari K; Mayeux, Richard R; Muzny, Donna M DM; Nasser, Waleed W; Neale, Benjamin B; Nho, Kwangsik K; Nicolas, Gaël G; Patel, Devanshi D; Pericak-Vance, Margaret A MA; Perola, Markus M; Psaty, Bruce M BM; Quenez, Olivier O; Rajabli, Farid F; Redon, Richard R; Reitz, Christiane C; Remes, Anne M AM; Salomaa, Veikko V; Sarnowski, Chloe C; Schmidt, Helena H; Schmidt, Michael M; Schmidt, Reinhold R; Soininen, Hilkka H; Thornton, Timothy A TA; Tosto, Giuseppe G; Tzourio, Christophe C; van der Lee, Sven J SJ; van Duijn, Cornelia M CM; Valladares, Otto O; Vardarajan, Badri B; Wang, Li-San LS; Wang, Weixin W; Wijsman, Ellen E; Wilson, Richard K RK; Witten, Daniela D; Worley, Kim C KC; Zhang, Xiaoling X; , ; Bellenguez, Celine C; Lambert, Jean-Charles JC; Kurki, Mitja I MI; Palotie, Aarno A; Daly, Mark M; Boerwinkle, Eric E; Lunetta, Kathryn L KL; Destefano, Anita L AL; Dupuis, Josée J; Martin, Eden R ER; Schellenberg, Gerard D GD; Seshadri, Sudha S; Naj, Adam C AC; Fornage, Myriam M; Farrer, Lindsay A LA
Bonham, Luke W LW; Karch, Celeste M CM; Fan, Chun C CC; Tan, Chin C; Geier, Ethan G EG; Wang, Yunpeng Y; Wen, Natalie N; Broce, Iris J IJ; Li, Yi Y; Barkovich, Matthew J MJ; Ferrari, Raffaele R; Hardy, John J; Momeni, Parastoo P; Höglinger, Günter G; Müller, Ulrich U; Hess, Christopher P CP; Sugrue, Leo P LP; Dillon, William P WP; Schellenberg, Gerard D GD; Miller, Bruce L BL; Andreassen, Ole A OA; Dale, Anders M AM; Barkovich, A James AJ; Yokoyama, Jennifer S JS; Desikan, Rahul S RS; , ; , ; ,
Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.
Jama Neurology
Karch, Celeste M CM; Wen, Natalie N; Fan, Chun C CC; Yokoyama, Jennifer S JS; Kouri, Naomi N; Ross, Owen A OA; Höglinger, Gunter G; Müller, Ulrich U; Ferrari, Raffaele R; Hardy, John J; Schellenberg, Gerard D GD; Sleiman, Patrick M PM; Momeni, Parastoo P; Hess, Christopher P CP; Miller, Bruce L BL; Sharma, Manu M; Van Deerlin, Vivianna V; Smeland, Olav B OB; Andreassen, Ole A OA; Dale, Anders M AM; Desikan, Rahul S RS; ,
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
Plos Medicine
Broce, Iris I; Karch, Celeste M CM; Wen, Natalie N; Fan, Chun C CC; Wang, Yunpeng Y; Tan, Chin Hong CH; Kouri, Naomi N; Ross, Owen A OA; Höglinger, Günter U GU; Muller, Ulrich U; Hardy, John J; , ; Momeni, Parastoo P; Hess, Christopher P CP; Dillon, William P WP; Miller, Zachary A ZA; Bonham, Luke W LW; Rabinovici, Gil D GD; Rosen, Howard J HJ; Schellenberg, Gerard D GD; Franke, Andre A; Karlsen, Tom H TH; Veldink, Jan H JH; Ferrari, Raffaele R; Yokoyama, Jennifer S JS; Miller, Bruce L BL; Andreassen, Ole A OA; Dale, Anders M AM; Desikan, Rahul S RS; Sugrue, Leo P LP
Large-scale identification of clinical and genetic predictors of motor progression in patients with newly diagnosed Parkinson's disease: a longitudinal cohort study and validation.
The Lancet. Neurology
Latourelle, Jeanne C JC; Beste, Michael T MT; Hadzi, Tiffany C TC; Miller, Robert E RE; Oppenheim, Jacob N JN; Valko, Matthew P MP; Wuest, Diane M DM; Church, Bruce W BW; Khalil, Iya G IG; Hayete, Boris B; Venuto, Charles S CS
A Bayesian mathematical model of motor and cognitive outcomes in Parkinson's disease.
Plos One
Hayete, Boris B; Wuest, Diane D; Laramie, Jason J; McDonagh, Paul P; Church, Bruce B; Eberly, Shirley S; Lang, Anthony A; Marek, Kenneth K; Runge, Karl K; Shoulson, Ira I; Singleton, Andrew A; Tanner, Caroline C; Khalil, Iya I; Verma, Ajay A; Ravina, Bernard B
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases.
Jama Neurology
Witoelar, Aree A; Jansen, Iris E IE; Wang, Yunpeng Y; Desikan, Rahul S RS; Gibbs, J Raphael JR; Blauwendraat, Cornelis C; Thompson, Wesley K WK; Hernandez, Dena G DG; Djurovic, Srdjan S; Schork, Andrew J AJ; Bettella, Francesco F; Ellinghaus, David D; Franke, Andre A; Lie, Benedicte A BA; McEvoy, Linda K LK; Karlsen, Tom H TH; Lesage, Suzanne S; Morris, Huw R HR; Brice, Alexis A; Wood, Nicholas W NW; Heutink, Peter P; Hardy, John J; Singleton, Andrew B AB; Dale, Anders M AM; Gasser, Thomas T; Andreassen, Ole A OA; Sharma, Manu M; ,
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia.
Acta Neuropathologica
Yokoyama, Jennifer S JS; Karch, Celeste M CM; Fan, Chun C CC; Bonham, Luke W LW; Kouri, Naomi N; Ross, Owen A OA; Rademakers, Rosa R; Kim, Jungsu J; Wang, Yunpeng Y; Höglinger, Günter U GU; Müller, Ulrich U; Ferrari, Raffaele R; Hardy, John J; , ; Momeni, Parastoo P; Sugrue, Leo P LP; Hess, Christopher P CP; James Barkovich, A A; Boxer, Adam L AL; Seeley, William W WW; Rabinovici, Gil D GD; Rosen, Howard J HJ; Miller, Bruce L BL; Schmansky, Nicholas J NJ; Fischl, Bruce B; Hyman, Bradley T BT; Dickson, Dennis W DW; Schellenberg, Gerard D GD; Andreassen, Ole A OA; Dale, Anders M AM; Desikan, Rahul S RS
Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations.
Plos One
Dinov, Ivo D ID; Heavner, Ben B; Tang, Ming M; Glusman, Gustavo G; Chard, Kyle K; Darcy, Mike M; Madduri, Ravi R; Pa, Judy J; Spino, Cathie C; Kesselman, Carl C; Foster, Ian I; Deutsch, Eric W EW; Price, Nathan D ND; Van Horn, John D JD; Ames, Joseph J; Clark, Kristi K; Hood, Leroy L; Hampstead, Benjamin M BM; Dauer, William W; Toga, Arthur W AW
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.
Cell Reports
Fumagalli, Debora D; Gacquer, David D; Rothé, Françoise F; Lefort, Anne A; Libert, Frederick F; Brown, David D; Kheddoumi, Naima N; Shlien, Adam A; Konopka, Tomasz T; Salgado, Roberto R; Larsimont, Denis D; Polyak, Kornelia K; Willard-Gallo, Karen K; Desmedt, Christine C; Piccart, Martine M; Abramowicz, Marc M; Campbell, Peter J PJ; Sotiriou, Christos C; Detours, Vincent V
A novel Alzheimer disease locus located near the gene encoding tau protein.
Molecular Psychiatry
Jun, G G; Ibrahim-Verbaas, C A CA; Vronskaya, M M; Lambert, J-C JC; Chung, J J; Naj, A C AC; Kunkle, B W BW; Wang, L-S LS; Bis, J C JC; Bellenguez, C C; Harold, D D; Lunetta, K L KL; Destefano, A L AL; Grenier-Boley, B B; Sims, R R; Beecham, G W GW; Smith, A V AV; Chouraki, V V; Hamilton-Nelson, K L KL; Ikram, M A MA; Fievet, N N; Denning, N N; Martin, E R ER; Schmidt, H H; Kamatani, Y Y; Dunstan, M L ML; Valladares, O O; Laza, A R AR; Zelenika, D D; Ramirez, A A; Foroud, T M TM; Choi, S-H SH; Boland, A A; Becker, T T; Kukull, W A WA; van der Lee, S J SJ; Pasquier, F F; Cruchaga, C C; Beekly, D D; Fitzpatrick, A L AL; Hanon, O O; Gill, M M; Barber, R R; Gudnason, V V; Campion, D D; Love, S S; Bennett, D A DA; Amin, N N; Berr, C C; Tsolaki, Magda M; Buxbaum, J D JD; Lopez, O L OL; Deramecourt, V V; Fox, N C NC; Cantwell, L B LB; Tárraga, L L; Dufouil, C C; Hardy, J J; Crane, P K PK; Eiriksdottir, G G; Hannequin, D D; Clarke, R R; Evans, D D; Mosley, T H TH; Letenneur, L L; Brayne, C C; Maier, W W; De Jager, P P; Emilsson, V V; Dartigues, J-F JF; Hampel, H H; Kamboh, M I MI; de Bruijn, R F A G RF; Tzourio, C C; Pastor, P P; Larson, E B EB; Rotter, J I JI; O'Donovan, M C MC; Montine, T J TJ; Nalls, M A MA; Mead, S S; Reiman, E M EM; Jonsson, P V PV; Holmes, C C; St George-Hyslop, P H PH; Boada, M M; Passmore, P P; Wendland, J R JR; Schmidt, R R; Morgan, K K; Winslow, A R AR; Powell, J F JF; Carasquillo, M M; Younkin, S G SG; Jakobsdóttir, J J; Kauwe, J S K JS; Wilhelmsen, K C KC; Rujescu, D D; Nöthen, M M MM; Hofman, A A; Jones, L L; , ; Haines, J L JL; Psaty, B M BM; Van Broeckhoven, C C; Holmans, P P; Launer, L J LJ; Mayeux, R R; Lathrop, M M; Goate, A M AM; Escott-Price, V V; Seshadri, S S; Pericak-Vance, M A MA; Amouyel, P P; Williams, J J; van Duijn, C M CM; Schellenberg, G D GD; Farrer, L A LA
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Nalls, Mike A MA; Saad, Mohamad M; Noyce, Alastair J AJ; Keller, Margaux F MF; Schrag, Anette A; Bestwick, Jonathan P JP; Traynor, Bryan J BJ; Gibbs, J Raphael JR; Hernandez, Dena G DG; Cookson, Mark R MR; Morris, Huw R HR; Williams, Nigel N; Gasser, Thomas T; Heutink, Peter P; Wood, Nick N; Hardy, John J; Martinez, Maria M; Singleton, Andrew B AB; , ; , ; , ; ,
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
Plos Genetics
Couch, Fergus J FJ; Wang, Xianshu X; McGuffog, Lesley L; Lee, Andrew A; Olswold, Curtis C; Kuchenbaecker, Karoline B KB; Soucy, Penny P; Fredericksen, Zachary Z; Barrowdale, Daniel D; Dennis, Joe J; Gaudet, Mia M MM; Dicks, Ed E; Kosel, Matthew M; Healey, Sue S; Sinilnikova, Olga M OM; Lee, Adam A; Bacot, François F; Vincent, Daniel D; Hogervorst, Frans B L FB; Peock, Susan S; Stoppa-Lyonnet, Dominique D; Jakubowska, Anna A; , ; Radice, Paolo P; Schmutzler, Rita Katharina RK; , ; Domchek, Susan M SM; Piedmonte, Marion M; Singer, Christian F CF; Friedman, Eitan E; Thomassen, Mads M; , ; Hansen, Thomas V O TV; Neuhausen, Susan L SL; Szabo, Csilla I CI; Blanco, Ignacio I; Greene, Mark H MH; Karlan, Beth Y BY; Garber, Judy J; Phelan, Catherine M CM; Weitzel, Jeffrey N JN; Montagna, Marco M; Olah, Edith E; Andrulis, Irene L IL; Godwin, Andrew K AK; Yannoukakos, Drakoulis D; Goldgar, David E DE; Caldes, Trinidad T; Nevanlinna, Heli H; Osorio, Ana A; Terry, Mary Beth MB; Daly, Mary B MB; van Rensburg, Elizabeth J EJ; Hamann, Ute U; Ramus, Susan J SJ; Toland, Amanda Ewart AE; Caligo, Maria A MA; Olopade, Olufunmilayo I OI; Tung, Nadine N; Claes, Kathleen K; Beattie, Mary S MS; Southey, Melissa C MC; Imyanitov, Evgeny N EN; Tischkowitz, Marc M; Janavicius, Ramunas R; John, Esther M EM; Kwong, Ava A; Diez, Orland O; Balmaña, Judith J; Barkardottir, Rosa B RB; Arun, Banu K BK; Rennert, Gad G; Teo, Soo-Hwang SH; Ganz, Patricia A PA; Campbell, Ian I; van der Hout, Annemarie H AH; van Deurzen, Carolien H M CH; Seynaeve, Caroline C; Gómez Garcia, Encarna B EB; van Leeuwen, Flora E FE; Meijers-Heijboer, Hanne E J HE; Gille, Johannes J P JJ; Ausems, Margreet G E M MG; Blok, Marinus J MJ; Ligtenberg, Marjolijn J L MJ; Rookus, Matti A MA; Devilee, Peter P; Verhoef, Senno S; van Os, Theo A M TA; Wijnen, Juul T JT; , ; , ; Frost, Debra D; Ellis, Steve S; Fineberg, Elena E; Platte, Radka R; Evans, D Gareth DG; Izatt, Louise L; Eeles, Rosalind A RA; Adlard, Julian J; Eccles, Diana M DM; Cook, Jackie J; Brewer, Carole C; Douglas, Fiona F; Hodgson, Shirley S; Morrison, Patrick J PJ; Side, Lucy E LE; Donaldson, Alan A; Houghton, Catherine C; Rogers, Mark T MT; Dorkins, Huw H; Eason, Jacqueline J; Gregory, Helen H; McCann, Emma E; Murray, Alex A; Calender, Alain A; Hardouin, Agnès A; Berthet, Pascaline P; Delnatte, Capucine C; Nogues, Catherine C; Lasset, Christine C; Houdayer, Claude C; Leroux, Dominique D; Rouleau, Etienne E; Prieur, Fabienne F; Damiola, Francesca F; Sobol, Hagay H; Coupier, Isabelle I; Venat-Bouvet, Laurence L; Castera, Laurent L; Gauthier-Villars, Marion M; Léoné, Mélanie M; Pujol, Pascal P; Mazoyer, Sylvie S; Bignon, Yves-Jean YJ; , ; Złowocka-Perłowska, Elżbieta E; Gronwald, Jacek J; Lubinski, Jan J; Durda, Katarzyna K; Jaworska, Katarzyna K; Huzarski, Tomasz T; Spurdle, Amanda B AB; Viel, Alessandra A; Peissel, Bernard B; Bonanni, Bernardo B; Melloni, Giulia G; Ottini, Laura L; Papi, Laura L; Varesco, Liliana L; Tibiletti, Maria Grazia MG; Peterlongo, Paolo P; Volorio, Sara S; Manoukian, Siranoush S; Pensotti, Valeria V; Arnold, Norbert N; Engel, Christoph C; Deissler, Helmut H; Gadzicki, Dorothea D; Gehrig, Andrea A; Kast, Karin K; Rhiem, Kerstin K; Meindl, Alfons A; Niederacher, Dieter D; Ditsch, Nina N; Plendl, Hansjoerg H; Preisler-Adams, Sabine S; Engert, Stefanie S; Sutter, Christian C; Varon-Mateeva, Raymonda R; Wappenschmidt, Barbara B; Weber, Bernhard H F BH; Arver, Brita B; Stenmark-Askmalm, Marie M; Loman, Niklas N; Rosenquist, Richard R; Einbeigi, Zakaria Z; Nathanson, Katherine L KL; Rebbeck, Timothy R TR; Blank, Stephanie V SV; Cohn, David E DE; Rodriguez, Gustavo C GC; Small, Laurie L; Friedlander, Michael M; Bae-Jump, Victoria L VL; Fink-Retter, Anneliese A; Rappaport, Christine C; Gschwantler-Kaulich, Daphne D; Pfeiler, Georg G; Tea, Muy-Kheng MK; Lindor, Noralane M NM; Kaufman, Bella B; Shimon Paluch, Shani S; Laitman, Yael Y; Skytte, Anne-Bine AB; Gerdes, Anne-Marie AM; Pedersen, Inge Sokilde IS; Moeller, Sanne Traasdahl ST; Kruse, Torben A TA; Jensen, Uffe Birk UB; Vijai, Joseph J; Sarrel, Kara K; Robson, Mark M; Kauff, Noah N; Mulligan, Anna Marie AM; Glendon, Gord G; Ozcelik, Hilmi H; Ejlertsen, Bent B; Nielsen, Finn C FC; Jønson, Lars L; Andersen, Mette K MK; Ding, Yuan Chun YC; Steele, Linda L; Foretova, Lenka L; Teulé, Alex A; Lazaro, Conxi C; Brunet, Joan J; Pujana, Miquel Angel MA; Mai, Phuong L PL; Loud, Jennifer T JT; Walsh, Christine C; Lester, Jenny J; Orsulic, Sandra S; Narod, Steven A SA; Herzog, Josef J; Sand, Sharon R SR; Tognazzo, Silvia S; Agata, Simona S; Vaszko, Tibor T; Weaver, Joellen J; Stavropoulou, Alexandra V AV; Buys, Saundra S SS; Romero, Atocha A; de la Hoya, Miguel M; Aittomäki, Kristiina K; Muranen, Taru A TA; Duran, Mercedes M; Chung, Wendy K WK; Lasa, Adriana A; Dorfling, Cecilia M CM; Miron, Alexander A; , ; Benitez, Javier J; Senter, Leigha L; Huo, Dezheng D; Chan, Salina B SB; Sokolenko, Anna P AP; Chiquette, Jocelyne J; Tihomirova, Laima L; Friebel, Tara M TM; Agnarsson, Bjarni A BA; Lu, Karen H KH; Lejbkowicz, Flavio F; James, Paul A PA; Hall, Per P; Dunning, Alison M AM; Tessier, Daniel D; Cunningham, Julie J; Slager, Susan L SL; Wang, Chen C; Hart, Steven S; Stevens, Kristen K; Simard, Jacques J; Pastinen, Tomi T; Pankratz, Vernon S VS; Offit, Kenneth K; Easton, Douglas F DF; Chenevix-Trench, Georgia G; Antoniou, Antonis C AC; ,
Human disease-associated genetic variation impacts large intergenic non-coding RNA expression.
Plos Genetics
Kumar, Vinod V; Westra, Harm-Jan HJ; Karjalainen, Juha J; Zhernakova, Daria V DV; Esko, Tõnu T; Hrdlickova, Barbara B; Almeida, Rodrigo R; Zhernakova, Alexandra A; Reinmaa, Eva E; Võsa, Urmo U; Hofker, Marten H MH; Fehrmann, Rudolf S N RS; Fu, Jingyuan J; Withoff, Sebo S; Metspalu, Andres A; Franke, Lude L; Wijmenga, Cisca C
An exploratory analysis on gene-environment interactions for Parkinson disease.
Neurobiology Of Aging
Gao, Jianjun J; Nalls, Michael A MA; Shi, Min M; Joubert, Bonnie R BR; Hernandez, Dena G DG; Huang, Xuemei X; Hollenbeck, Albert A; Singleton, Andrew B AB; Chen, Honglei H
Structural diversity and African origin of the 17q21.31 inversion polymorphism.
Nature Genetics
Steinberg, Karyn Meltz KM; Antonacci, Francesca F; Sudmant, Peter H PH; Kidd, Jeffrey M JM; Campbell, Catarina D CD; Vives, Laura L; Malig, Maika M; Scheinfeldt, Laura L; Beggs, William W; Ibrahim, Muntaser M; Lema, Godfrey G; Nyambo, Thomas B TB; Omar, Sabah A SA; Bodo, Jean-Marie JM; Froment, Alain A; Donnelly, Michael P MP; Kidd, Kenneth K KK; Tishkoff, Sarah A SA; Eichler, Evan E EE
No association between Parkinson disease alleles and the risk of melanoma.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Meng, Shasha S; Song, Fengju F; Chen, Honglei H; Gao, Xiang X; Amos, Christopher I CI; Lee, Jeffrey E JE; Wei, Qingyi Q; Qureshi, Abrar A AA; Han, Jiali J
Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee.
Plos Genetics
Hamza, Taye H TH; Chen, Honglei H; Hill-Burns, Erin M EM; Rhodes, Shannon L SL; Montimurro, Jennifer J; Kay, Denise M DM; Tenesa, Albert A; Kusel, Victoria I VI; Sheehan, Patricia P; Eaaswarkhanth, Muthukrishnan M; Yearout, Dora D; Samii, Ali A; Roberts, John W JW; Agarwal, Pinky P; Bordelon, Yvette Y; Park, Yikyung Y; Wang, Liyong L; Gao, Jianjun J; Vance, Jeffery M JM; Kendler, Kenneth S KS; Bacanu, Silviu-Alin SA; Scott, William K WK; Ritz, Beate B; Nutt, John J; Factor, Stewart A SA; Zabetian, Cyrus P CP; Payami, Haydeh H
Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.
Bmc Medical Genetics
Liu, Xinmin X; Cheng, Rong R; Verbitsky, Miguel M; Kisselev, Sergey S; Browne, Andrew A; Mejia-Sanatana, Helen H; Louis, Elan D ED; Cote, Lucien J LJ; Andrews, Howard H; Waters, Cheryl C; Ford, Blair B; Frucht, Steven S; Fahn, Stanley S; Marder, Karen K; Clark, Lorraine N LN; Lee, Joseph H JH
Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease.
Movement Disorders : Official Journal Of The Movement Disorder Society
Mata, Ignacio F IF; Yearout, Dora D; Alvarez, Victoria V; Coto, Eliecer E; de Mena, Lorena L; Ribacoba, Renee R; Lorenzo-Betancor, Oswaldo O; Samaranch, Lluis L; Pastor, Pau P; Cervantes, Sebastian S; Infante, Jon J; Garcia-Gorostiaga, Ines I; Sierra, Maria M; Combarros, Onofre O; Snapinn, Katherine W KW; Edwards, Karen L KL; Zabetian, Cyrus P CP
Genome-wide association study confirms extant PD risk loci among the Dutch.
European Journal Of Human Genetics : Ejhg
Simón-Sánchez, Javier J; van Hilten, Jacobus J JJ; van de Warrenburg, Bart B; Post, Bart B; Berendse, Henk W HW; Arepalli, Sampath S; Hernandez, Dena G DG; de Bie, Rob M A RM; Velseboer, Daan D; Scheffer, Hans H; Bloem, Bas B; van Dijk, Karin D KD; Rivadeneira, Fernando F; Hofman, Albert A; Uitterlinden, André G AG; Rizzu, Patrizia P; Bochdanovits, Zoltan Z; Singleton, Andrew B AB; Heutink, Peter P
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.
Nature Genetics
Hamza, Taye H TH; Zabetian, Cyrus P CP; Tenesa, Albert A; Laederach, Alain A; Montimurro, Jennifer J; Yearout, Dora D; Kay, Denise M DM; Doheny, Kimberly F KF; Paschall, Justin J; Pugh, Elizabeth E; Kusel, Victoria I VI; Collura, Randall R; Roberts, John J; Griffith, Alida A; Samii, Ali A; Scott, William K WK; Nutt, John J; Factor, Stewart A SA; Payami, Haydeh H
Genome-wide association study reveals genetic risk underlying Parkinson's disease.
Nature Genetics
Simón-Sánchez, Javier J; Schulte, Claudia C; Bras, Jose M JM; Sharma, Manu M; Gibbs, J Raphael JR; Berg, Daniela D; Paisan-Ruiz, Coro C; Lichtner, Peter P; Scholz, Sonja W SW; Hernandez, Dena G DG; Krüger, Rejko R; Federoff, Monica M; Klein, Christine C; Goate, Alison A; Perlmutter, Joel J; Bonin, Michael M; Nalls, Michael A MA; Illig, Thomas T; Gieger, Christian C; Houlden, Henry H; Steffens, Michael M; Okun, Michael S MS; Racette, Brad A BA; Cookson, Mark R MR; Foote, Kelly D KD; Fernandez, Hubert H HH; Traynor, Bryan J BJ; Schreiber, Stefan S; Arepalli, Sampath S; Zonozi, Ryan R; Gwinn, Katrina K; van der Brug, Marcel M; Lopez, Grisel G; Chanock, Stephen J SJ; Schatzkin, Arthur A; Park, Yikyung Y; Hollenbeck, Albert A; Gao, Jianjun J; Huang, Xuemei X; Wood, Nick W NW; Lorenz, Delia D; Deuschl, Günther G; Chen, Honglei H; Riess, Olaf O; Hardy, John A JA; Singleton, Andrew B AB; Gasser, Thomas T