Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits.
Scientific Reports
Deming, Yuetiva Y; Xia, Jian J; Cai, Yefei Y; Lord, Jenny J; Del-Aguila, Jorge L JL; Fernandez, Maria Victoria MV; Carrell, David D; Black, Kathleen K; Budde, John J; Ma, ShengMei S; Saef, Benjamin B; Howells, Bill B; Bertelsen, Sarah S; Bailey, Matthew M; Ridge, Perry G PG; , ; Holtzman, David D; Morris, John C JC; Bales, Kelly K; Pickering, Eve H EH; Lee, Jin-Moo JM; Heitsch, Laura L; Kauwe, John J; Goate, Alison A; Piccio, Laura L; Cruchaga, Carlos C
Publication Date: 2016-01-04
Variant appearance in text: APOH: W335S; rs1801690
Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Jama Network Open
Yang, Wenjian W; Karol, Seth E SE; Hoshitsuki, Keito K; Lee, Shawn S; Larsen, Eric C EC; Winick, Naomi N; Carroll, William L WL; Loh, Mignon L ML; Raetz, Elizabeth A EA; Hunger, Stephen P SP; Winter, Stuart S SS; Dunsmore, Kimberly P KP; Devidas, Meenakshi M; Relling, Mary V MV; Yang, Jun J JJ
Genetic variants associated with circulating liver injury markers in Mexican Americans, a population at risk for non-alcoholic fatty liver disease.
Frontiers In Genetics
Sabotta, Caroline M CM; Kwan, Suet-Ying SY; Petty, Lauren E LE; Below, Jennifer E JE; Joon, Aron A; Wei, Peng P; Fisher-Hoch, Susan P SP; McCormick, Joseph B JB; Beretta, Laura L
Tissue-specific multi-omics analysis of atrial fibrillation.
Nature Communications
Assum, Ines I; Krause, Julia J; Scheinhardt, Markus O MO; Müller, Christian C; Hammer, Elke E; Börschel, Christin S CS; Völker, Uwe U; Conradi, Lenard L; Geelhoed, Bastiaan B; Zeller, Tanja T; Schnabel, Renate B RB; Heinig, Matthias M
Tissue-specific multi-omics analysis of atrial fibrillation.
Nature Communications
Assum, Ines I; Krause, Julia J; Scheinhardt, Markus O MO; Müller, Christian C; Hammer, Elke E; Börschel, Christin S CS; Völker, Uwe U; Conradi, Lenard L; Geelhoed, Bastiaan B; Zeller, Tanja T; Schnabel, Renate B RB; Heinig, Matthias M
Levels of Angiotensin-Converting Enzyme and Apolipoproteins Are Associated with Alzheimer's Disease and Cardiovascular Diseases.
Cells
Xu, Chun C; Garcia, Debra D; Lu, Yongke Y; Ozuna, Kaysie K; Adjeroh, Donald A DA; Wang, Kesheng K; On Behalf Of The Alzheimer's Disease Neuroimaging Initiative,
Levels of Angiotensin-Converting Enzyme and Apolipoproteins Are Associated with Alzheimer's Disease and Cardiovascular Diseases.
Cells
Xu, Chun C; Garcia, Debra D; Lu, Yongke Y; Ozuna, Kaysie K; Adjeroh, Donald A DA; Wang, Kesheng K; On Behalf Of The Alzheimer's Disease Neuroimaging Initiative,
Genome-wide association study of cardiac troponin I in the general population.
Human Molecular Genetics
Moksnes, Marta R MR; Røsjø, Helge H; Richmond, Anne A; Lyngbakken, Magnus N MN; Graham, Sarah E SE; Hansen, Ailin Falkmo AF; Wolford, Brooke N BN; Gagliano Taliun, Sarah A SA; LeFaive, Jonathon J; Rasheed, Humaira H; Thomas, Laurent F LF; Zhou, Wei W; Aung, Nay N; Surakka, Ida I; Douville, Nicholas J NJ; Campbell, Archie A; Porteous, David J DJ; Petersen, Steffen E SE; Munroe, Patricia B PB; Welsh, Paul P; Sattar, Naveed N; Smith, George Davey GD; Fritsche, Lars G LG; Nielsen, Jonas B JB; Åsvold, Bjørn Olav BO; Hveem, Kristian K; Hayward, Caroline C; Willer, Cristen J CJ; Brumpton, Ben M BM; Omland, Torbjørn T
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.
Cell
Krug, Karsten K; Jaehnig, Eric J EJ; Satpathy, Shankha S; Blumenberg, Lili L; Karpova, Alla A; Anurag, Meenakshi M; Miles, George G; Mertins, Philipp P; Geffen, Yifat Y; Tang, Lauren C LC; Heiman, David I DI; Cao, Song S; Maruvka, Yosef E YE; Lei, Jonathan T JT; Huang, Chen C; Kothadia, Ramani B RB; Colaprico, Antonio A; Birger, Chet C; Wang, Jarey J; Dou, Yongchao Y; Wen, Bo B; Shi, Zhiao Z; Liao, Yuxing Y; Wiznerowicz, Maciej M; Wyczalkowski, Matthew A MA; Chen, Xi Steven XS; Kennedy, Jacob J JJ; Paulovich, Amanda G AG; Thiagarajan, Mathangi M; Kinsinger, Christopher R CR; Hiltke, Tara T; Boja, Emily S ES; Mesri, Mehdi M; Robles, Ana I AI; Rodriguez, Henry H; Westbrook, Thomas F TF; Ding, Li L; Getz, Gad G; Clauser, Karl R KR; Fenyö, David D; Ruggles, Kelly V KV; Zhang, Bing B; Mani, D R DR; Carr, Steven A SA; Ellis, Matthew J MJ; Gillette, Michael A MA; ,
GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer.
Nature Communications
Zhou, Wei W; Brumpton, Ben B; Kabil, Omer O; Gudmundsson, Julius J; Thorleifsson, Gudmar G; Weinstock, Josh J; Zawistowski, Matthew M; Nielsen, Jonas B JB; Chaker, Layal L; Medici, Marco M; Teumer, Alexander A; Naitza, Silvia S; Sanna, Serena S; Schultheiss, Ulla T UT; Cappola, Anne A; Karjalainen, Juha J; Kurki, Mitja M; Oneka, Morgan M; Taylor, Peter P; Fritsche, Lars G LG; Graham, Sarah E SE; Wolford, Brooke N BN; Overton, William W; Rasheed, Humaira H; Haug, Eirin B EB; Gabrielsen, Maiken E ME; Skogholt, Anne Heidi AH; Surakka, Ida I; Davey Smith, George G; Pandit, Anita A; Roychowdhury, Tanmoy T; Hornsby, Whitney E WE; Jonasson, Jon G JG; Senter, Leigha L; Liyanarachchi, Sandya S; Ringel, Matthew D MD; Xu, Li L; Kiemeney, Lambertus A LA; He, Huiling H; Netea-Maier, Romana T RT; Mayordomo, Jose I JI; Plantinga, Theo S TS; Hrafnkelsson, Jon J; Hjartarson, Hannes H; Sturgis, Erich M EM; Palotie, Aarno A; Daly, Mark M; Citterio, Cintia E CE; Arvan, Peter P; Brummett, Chad M CM; Boehnke, Michael M; de la Chapelle, Albert A; Stefansson, Kari K; Hveem, Kristian K; Willer, Cristen J CJ; Åsvold, Bjørn Olav BO
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: APOH: W335S; rs1801690
In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta.
Elife
Pernemalm, Maria M; Sandberg, AnnSofi A; Zhu, Yafeng Y; Boekel, Jorrit J; Tamburro, Davide D; Schwenk, Jochen M JM; Björk, Albin A; Wahren-Herlenius, Marie M; Åmark, Hanna H; Östenson, Claes-Göran CG; Westgren, Magnus M; Lehtiö, Janne J
Publication Date: 2019-04-08
Variant appearance in text: APOH: 1004G>C; W335S; rs1801690
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
The Journal Of Pathology
Maguire, Sarah L SL; Peck, Barrie B; Wai, Patty T PT; Campbell, James J; Barker, Holly H; Gulati, Aditi A; Daley, Frances F; Vyse, Simon S; Huang, Paul P; Lord, Christopher J CJ; Farnie, Gillian G; Brennan, Keith K; Natrajan, Rachael R
Publication Date: 2016-11
Variant appearance in text: APOH: W335S; rs1801690
Proteogenomics connects somatic mutations to signalling in breast cancer.
Nature
Mertins, Philipp P; Mani, D R DR; Ruggles, Kelly V KV; Gillette, Michael A MA; Clauser, Karl R KR; Wang, Pei P; Wang, Xianlong X; Qiao, Jana W JW; Cao, Song S; Petralia, Francesca F; Kawaler, Emily E; Mundt, Filip F; Krug, Karsten K; Tu, Zhidong Z; Lei, Jonathan T JT; Gatza, Michael L ML; Wilkerson, Matthew M; Perou, Charles M CM; Yellapantula, Venkata V; Huang, Kuan-lin KL; Lin, Chenwei C; McLellan, Michael D MD; Yan, Ping P; Davies, Sherri R SR; Townsend, R Reid RR; Skates, Steven J SJ; Wang, Jing J; Zhang, Bing B; Kinsinger, Christopher R CR; Mesri, Mehdi M; Rodriguez, Henry H; Ding, Li L; Paulovich, Amanda G AG; Fenyö, David D; Ellis, Matthew J MJ; Carr, Steven A SA; ,
PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.
Plos Computational Biology
Bendl, Jaroslav J; Musil, Miloš M; Štourač, Jan J; Zendulka, Jaroslav J; Damborský, Jiří J; Brezovský, Jan J
Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults.
Scientific Reports
Mather, Karen A KA; Thalamuthu, Anbupalam A; Oldmeadow, Christopher C; Song, Fei F; Armstrong, Nicola J NJ; Poljak, Anne A; Holliday, Elizabeth G EG; McEvoy, Mark M; Kwok, John B JB; Assareh, Amelia A AA; Reppermund, Simone S; Kochan, Nicole A NA; Lee, Teresa T; Ames, David D; Wright, Margaret J MJ; Trollor, Julian N JN; Schofield, Peter W PW; Brodaty, Henry H; Scott, Rodney J RJ; Schofield, Peter R PR; Attia, John R JR; Sachdev, Perminder S PS
Publication Date: 2016-03-31
Variant appearance in text: APOH: Trp335Ser; rs1801690
Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study.
Plos One
About, Frédégonde F; Oudot-Mellakh, Tiphaine T; Niay, Jonathan J; Rabiéga, Pascaline P; Pedergnana, Vincent V; Duffy, Darragh D; Sultanik, Philippe P; Cagnot, Carole C; Carrat, Fabrice F; Marcellin, Patrick P; Zoulim, Fabien F; Larrey, Dominique D; Hézode, Christophe C; Fontaine, Hélène H; Bronowicki, Jean-Pierre JP; Pol, Stanislas S; Albert, Matthew L ML; Theodorou, Ioannis I; Cobat, Aurélie A; Abel, Laurent L; ,
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: APOH: W335S; rs1801690
NCI-60 whole exome sequencing and pharmacological CellMiner analyses.
Plos One
Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y
Publication Date: 2014
Variant appearance in text: APOH: W335S; rs1801690
Genome-wide association study of antiphospholipid antibodies.
Autoimmune Diseases
Kamboh, M Ilyas MI; Wang, Xingbin X; Kao, Amy H AH; Barmada, Michael M MM; Clarke, Ann A; Ramsey-Goldman, Rosalind R; Manzi, Susan S; Demirci, F Yesim FY
Genetic risk factors for thrombosis in systemic lupus erythematosus.
The Journal Of Rheumatology
Kaiser, Rachel R; Li, Yonghong Y; Chang, Monica M; Catanese, Joseph J; Begovich, Ann B AB; Brown, Elizabeth E EE; Edberg, Jeffrey C JC; McGwin, Gerald G; Alarcón, Graciela S GS; Ramsey-Goldman, Rosalind R; Reveille, John D JD; Vilá, Luis M LM; Petri, Michelle A MA; Kimberly, Robert P RP; Taylor, Kimberly E KE; Criswell, Lindsey A LA
Interpretome: a freely available, modular, and secure personal genome interpretation engine.
Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing
Karczewski, Konrad J KJ; Tirrell, Robert P RP; Cordero, Pablo P; Tatonetti, Nicholas P NP; Dudley, Joel T JT; Salari, Keyan K; Snyder, Michael M; Altman, Russ B RB; Kim, Stuart K SK