The genetic regulation of protein expression in cerebrospinal fluid.
Embo Molecular Medicine
Hansson, Oskar O; Kumar, Atul A; Janelidze, Shorena S; Stomrud, Erik E; Insel, Philip S PS; Blennow, Kaj K; Zetterberg, Henrik H; Fauman, Eric E; Hedman, Åsa K ÅK; Nagle, Michael W MW; Whelan, Christopher D CD; Baird, Denis D; Mälarstig, Anders A; Mattsson-Carlgren, Niklas N
Genetic analysis of over half a million people characterises C-reactive protein loci.
Nature Communications
Said, Saredo S; Pazoki, Raha R; Karhunen, Ville V; Võsa, Urmo U; Ligthart, Symen S; Bodinier, Barbara B; Koskeridis, Fotios F; Welsh, Paul P; Alizadeh, Behrooz Z BZ; Chasman, Daniel I DI; Sattar, Naveed N; Chadeau-Hyam, Marc M; Evangelou, Evangelos E; Jarvelin, Marjo-Riitta MR; Elliott, Paul P; Tzoulaki, Ioanna I; Dehghan, Abbas A
Genetically determined elevated C-reactive protein associated with primary colorectal cancer risk: Mendelian randomization with lifestyle interactions.
American Journal Of Cancer Research
Jung, Su Yon SY; Yu, Herbert H; Pellegrini, Matteo M; Papp, Jeanette C JC; Sobel, Eric M EM; Zhang, Zuo-Feng ZF
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
American Journal Of Human Genetics
Ligthart, Symen S; Vaez, Ahmad A; Võsa, Urmo U; Stathopoulou, Maria G MG; de Vries, Paul S PS; Prins, Bram P BP; Van der Most, Peter J PJ; Tanaka, Toshiko T; Naderi, Elnaz E; Rose, Lynda M LM; Wu, Ying Y; Karlsson, Robert R; Barbalic, Maja M; Lin, Honghuang H; Pool, René R; Zhu, Gu G; Macé, Aurélien A; Sidore, Carlo C; Trompet, Stella S; Mangino, Massimo M; Sabater-Lleal, Maria M; Kemp, John P JP; Abbasi, Ali A; Kacprowski, Tim T; Verweij, Niek N; Smith, Albert V AV; Huang, Tao T; Marzi, Carola C; Feitosa, Mary F MF; Lohman, Kurt K KK; Kleber, Marcus E ME; Milaneschi, Yuri Y; Mueller, Christian C; Huq, Mahmudul M; Vlachopoulou, Efthymia E; Lyytikäinen, Leo-Pekka LP; Oldmeadow, Christopher C; Deelen, Joris J; Perola, Markus M; Zhao, Jing Hua JH; Feenstra, Bjarke B; , ; Amini, Marzyeh M; , ; Lahti, Jari J; Schraut, Katharina E KE; Fornage, Myriam M; Suktitipat, Bhoom B; Chen, Wei-Min WM; Li, Xiaohui X; Nutile, Teresa T; Malerba, Giovanni G; Luan, Jian'an J; Bak, Tom T; Schork, Nicholas N; 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Mendes de Leon, Carlos F CF; Bottinger, Erwin P EP; Kloppenburg, Margreet M; Paternoster, Lavinia L; Boehnke, Michael M; Musk, A W AW; Willemsen, Gonneke G; Evans, David M DM; Madden, Pamela A F PAF; Kähönen, Mika M; Kutalik, Zoltán Z; Zoledziewska, Magdalena M; Karhunen, Ville V; Kritchevsky, Stephen B SB; Sattar, Naveed N; Lachance, Genevieve G; Clarke, Robert R; Harris, Tamara B TB; Raitakari, Olli T OT; Attia, John R JR; van Heemst, Diana D; Kajantie, Eero E; Sorice, Rossella R; Gambaro, Giovanni G; Scott, Robert A RA; Hicks, Andrew A AA; Ferrucci, Luigi L; Standl, Marie M; Lindgren, Cecilia M CM; Starr, John M JM; Karlsson, Magnus M; Lind, Lars L; Li, Jun Z JZ; Chambers, John C JC; Mori, Trevor A TA; de Geus, Eco J C N EJCN; Heath, Andrew C AC; Martin, Nicholas G NG; Auvinen, Juha J; Buckley, Brendan M BM; de Craen, Anton J M AJM; Waldenberger, Melanie M; Strauch, Konstantin K; Meitinger, Thomas T; Scott, Rodney J RJ; McEvoy, Mark M; Beekman, Marian M; Bombieri, Cristina C; Ridker, Paul M PM; 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Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.
Plos One
de Vries, Paul S PS; Sabater-Lleal, Maria M; Chasman, Daniel I DI; Trompet, Stella S; Ahluwalia, Tarunveer S TS; Teumer, Alexander A; Kleber, Marcus E ME; Chen, Ming-Huei MH; Wang, Jie Jin JJ; Attia, John R JR; Marioni, Riccardo E RE; Steri, Maristella M; Weng, Lu-Chen LC; Pool, Rene R; Grossmann, Vera V; Brody, Jennifer A JA; Venturini, Cristina C; Tanaka, Toshiko T; Rose, Lynda M LM; Oldmeadow, Christopher C; Mazur, Johanna J; Basu, Saonli S; Frånberg, Mattias M; Yang, Qiong Q; Ligthart, Symen S; Hottenga, Jouke J JJ; Rumley, Ann A; Mulas, Antonella A; de Craen, Anton J M AJ; Grotevendt, Anne A; Taylor, Kent D KD; Delgado, Graciela E GE; Kifley, Annette A; Lopez, Lorna M LM; Berentzen, Tina L TL; Mangino, Massimo M; Bandinelli, Stefania S; Morrison, Alanna C AC; Hamsten, Anders A; Tofler, Geoffrey G; de Maat, Moniek P M MP; Draisma, Harmen H M HH; Lowe, Gordon D GD; Zoledziewska, Magdalena M; Sattar, Naveed N; Lackner, Karl J KJ; Völker, Uwe U; McKnight, Barbara B; Huang, Jie J; Holliday, Elizabeth G EG; McEvoy, Mark A MA; Starr, John M JM; Hysi, Pirro G PG; Hernandez, Dena G DG; Guan, Weihua W; Rivadeneira, Fernando F; McArdle, Wendy L WL; Slagboom, P Eline PE; Zeller, Tanja T; Psaty, Bruce M BM; Uitterlinden, André G AG; de Geus, Eco J C EJ; Stott, David J DJ; Binder, Harald H; Hofman, Albert A; Franco, Oscar H OH; Rotter, Jerome I JI; Ferrucci, Luigi L; Spector, Tim D TD; Deary, Ian J IJ; März, Winfried W; Greinacher, Andreas A; Wild, Philipp S PS; Cucca, Francesco F; Boomsma, Dorret I DI; Watkins, Hugh H; Tang, Weihong W; Ridker, Paul M PM; Jukema, Jan W JW; Scott, Rodney J RJ; Mitchell, Paul P; Hansen, Torben T; O'Donnell, Christopher J CJ; Smith, Nicholas L NL; Strachan, David P DP; Dehghan, Abbas A
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
Human Molecular Genetics
de Vries, Paul S PS; Chasman, Daniel I DI; Sabater-Lleal, Maria M; Chen, Ming-Huei MH; Huffman, Jennifer E JE; Steri, Maristella M; Tang, Weihong W; Teumer, Alexander A; Marioni, Riccardo E RE; Grossmann, Vera V; Hottenga, Jouke J JJ; Trompet, Stella S; Müller-Nurasyid, Martina M; Zhao, Jing Hua JH; Brody, Jennifer A JA; Kleber, Marcus E ME; Guo, Xiuqing X; Wang, Jie Jin JJ; Auer, Paul L PL; Attia, John R JR; Yanek, Lisa R LR; Ahluwalia, Tarunveer S TS; Lahti, Jari J; Venturini, Cristina C; Tanaka, Toshiko T; Bielak, Lawrence F LF; Joshi, Peter K PK; Rocanin-Arjo, Ares A; Kolcic, Ivana I; Navarro, Pau P; Rose, Lynda M LM; Oldmeadow, Christopher C; Riess, Helene H; Mazur, Johanna J; Basu, Saonli S; Goel, Anuj A; Yang, Qiong Q; Ghanbari, Mohsen M; Willemsen, Gonneke G; Rumley, Ann A; Fiorillo, Edoardo E; de Craen, Anton J M AJ; Grotevendt, Anne A; Scott, Robert R; Taylor, Kent D KD; Delgado, Graciela E GE; Yao, Jie J; Kifley, Annette A; Kooperberg, Charles C; Qayyum, Rehan R; Lopez, Lorna M LM; Berentzen, Tina L TL; Räikkönen, Katri K; Mangino, Massimo M; Bandinelli, Stefania S; Peyser, Patricia A PA; Wild, Sarah S; Trégouët, David-Alexandre DA; Wright, Alan F AF; Marten, Jonathan J; Zemunik, Tatijana T; Morrison, Alanna C AC; Sennblad, Bengt B; Tofler, Geoffrey G; de Maat, Moniek P M MP; de Geus, Eco J C EJ; Lowe, Gordon D GD; Zoledziewska, Magdalena M; Sattar, Naveed N; Binder, Harald H; Völker, Uwe U; Waldenberger, Melanie M; Khaw, Kay-Tee KT; Mcknight, Barbara B; Huang, Jie J; Jenny, Nancy S NS; Holliday, Elizabeth G EG; Qi, Lihong L; Mcevoy, Mark G MG; Becker, Diane M DM; Starr, John M JM; Sarin, Antti-Pekka AP; Hysi, Pirro G PG; Hernandez, Dena G DG; Jhun, Min A MA; Campbell, Harry H; Hamsten, Anders A; Rivadeneira, Fernando F; Mcardle, Wendy L WL; Slagboom, P Eline PE; Zeller, Tanja T; Koenig, Wolfgang W; Psaty, Bruce M BM; Haritunians, Talin T; Liu, Jingmin J; Palotie, Aarno A; Uitterlinden, André G AG; Stott, David J DJ; Hofman, Albert A; Franco, Oscar H OH; Polasek, Ozren O; Rudan, Igor I; Morange, Pierre-Emmanuel PE; Wilson, James F JF; Kardia, Sharon L R SL; Ferrucci, Luigi L; Spector, Tim D TD; Eriksson, Johan G JG; Hansen, Torben T; Deary, Ian J IJ; Becker, Lewis C LC; Scott, Rodney J RJ; Mitchell, Paul P; März, Winfried W; Wareham, Nick J NJ; Peters, Annette A; Greinacher, Andreas A; Wild, Philipp S PS; Jukema, J Wouter JW; Boomsma, Dorret I DI; Hayward, Caroline C; Cucca, Francesco F; Tracy, Russell R; Watkins, Hugh H; Reiner, Alex P AP; Folsom, Aaron R AR; Ridker, Paul M PM; O'Donnell, Christopher J CJ; Smith, Nicholas L NL; Strachan, David P DP; Dehghan, Abbas A
No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects.
Plos One
Baumert, Jens J; Huang, Jie J; McKnight, Barbara B; Sabater-Lleal, Maria M; Steri, Maristella M; Chu, Audrey Y AY; Trompet, Stella S; Lopez, Lorna M LM; Fornage, Myriam M; Teumer, Alexander A; Tang, Weihong W; Rudnicka, Alicja R AR; Mälarstig, Anders A; Hottenga, Jouke-Jan JJ; Kavousi, Maryam M; Lahti, Jari J; Tanaka, Toshiko T; Hayward, Caroline C; Huffman, Jennifer E JE; Morange, Pierre-Emmanuel PE; Rose, Lynda M LM; Basu, Saonli S; Rumley, Ann A; Stott, David J DJ; Buckley, Brendan M BM; de Craen, Anton J M AJ; Sanna, Serena S; Masala, Marco M; Biffar, Reiner R; Homuth, Georg G; Silveira, Angela A; Sennblad, Bengt B; Goel, Anuj A; Watkins, Hugh H; Müller-Nurasyid, Martina M; Rückerl, Regina R; Taylor, Kent K; Chen, Ming-Huei MH; de Geus, Eco J C EJ; Hofman, Albert A; Witteman, Jacqueline C M JC; de Maat, Moniek P M MP; Palotie, Aarno A; Davies, Gail G; Siscovick, David S DS; Kolcic, Ivana I; Wild, Sarah H SH; Song, Jaejoon J; McArdle, Wendy L WL; Ford, Ian I; Sattar, Naveed N; Schlessinger, David D; Grotevendt, Anne A; Franzosi, Maria Grazia MG; Illig, Thomas T; Waldenberger, Melanie M; Lumley, Thomas T; Tofler, Geoffrey H GH; Willemsen, Gonneke G; Uitterlinden, André G AG; Rivadeneira, Fernando F; Räikkönen, Katri K; Chasman, Daniel I DI; Folsom, Aaron R AR; Lowe, Gordon D GD; Westendorp, Rudi G J RG; Slagboom, P Eline PE; Cucca, Francesco F; Wallaschofski, Henri H; Strawbridge, Rona J RJ; Seedorf, Udo U; Koenig, Wolfgang W; Bis, Joshua C JC; Mukamal, Kenneth J KJ; van Dongen, Jenny J; Widen, Elisabeth E; Franco, Oscar H OH; Starr, John M JM; Liu, Kiang K; Ferrucci, Luigi L; Polasek, Ozren O; Wilson, James F JF; Oudot-Mellakh, Tiphaine T; Campbell, Harry H; Navarro, Pau P; Bandinelli, Stefania S; Eriksson, Johan J; Boomsma, Dorret I DI; Dehghan, Abbas A; Clarke, Robert R; Hamsten, Anders A; Boerwinkle, Eric E; Jukema, J Wouter JW; Naitza, Silvia S; Ridker, Paul M PM; Völzke, Henry H; Deary, Ian J IJ; Reiner, Alexander P AP; Trégouët, David-Alexandre DA; O'Donnell, Christopher J CJ; Strachan, David P DP; Peters, Annette A; Smith, Nicholas L NL
Heritability and genomics of gene expression in peripheral blood.
Nature Genetics
Wright, Fred A FA; Sullivan, Patrick F PF; Brooks, Andrew I AI; Zou, Fei F; Sun, Wei W; Xia, Kai K; Madar, Vered V; Jansen, Rick R; Chung, Wonil W; Zhou, Yi-Hui YH; Abdellaoui, Abdel A; Batista, Sandra S; Butler, Casey C; Chen, Guanhua G; Chen, Ting-Huei TH; D'Ambrosio, David D; Gallins, Paul P; Ha, Min Jin MJ; Hottenga, Jouke Jan JJ; Huang, Shunping S; Kattenberg, Mathijs M; Kochar, Jaspreet J; Middeldorp, Christel M CM; Qu, Ani A; Shabalin, Andrey A; Tischfield, Jay J; Todd, Laura L; Tzeng, Jung-Ying JY; van Grootheest, Gerard G; Vink, Jacqueline M JM; Wang, Qi Q; Wang, Wei W; Wang, Weibo W; Willemsen, Gonneke G; Smit, Johannes H JH; de Geus, Eco J EJ; Yin, Zhaoyu Z; Penninx, Brenda W J H BW; Boomsma, Dorret I DI
Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.
Nucleic Acids Research
Feldmann, Radmila R; Fischer, Cornelius C; Kodelja, Vitam V; Behrens, Sarah S; Haas, Stefan S; Vingron, Martin M; Timmermann, Bernd B; Geikowski, Anne A; Sauer, Sascha S
Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development.
Arteriosclerosis, Thrombosis, And Vascular Biology
Williams, Marlene S MS; Weiss, Ethan J EJ; Sabatine, Marc S MS; Simon, Daniel I DI; Bahou, Wadie F WF; Becker, Lewis C LC; Parise, Leslie V LV; Dauerman, Harold L HL; French, Patricia A PA; Smyth, Susan S SS; Becker, Richard C RC; ,
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
Circulation. Cardiovascular Genetics
Danik, Jacqueline S JS; Paré, Guillaume G; Chasman, Daniel I DI; Zee, Robert Y L RY; Kwiatkowski, David J DJ; Parker, Alex A; Miletich, Joseph P JP; Ridker, Paul M PM