Publications:

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PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth.

Nature Communications

Cai, Weijia W; Su, Liya L; Liao, Lili L; Liu, Zongzhi Z ZZ; Langbein, Lauren L; Dulaimi, Essel E; Testa, Joseph R JR; Uzzo, Robert G RG; Zhong, Zhijiu Z; Jiang, Wei W; Yan, Qin Q; Zhang, Qing Q; Yang, Haifeng H

Publication Date: 2019-12-20

Variant appearance in text: p53: K382Q

PubMed Link: 31863007

Variant Present in the following documents:

• Main text
• 41467_2019_Article_13608.pdf
• 41467_2019_13608_MOESM2_ESM.pdf

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Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis.

The Journal Of Biological Chemistry

Choi, Seo-Hyun SH; Koh, Dong-In DI; Cho, Su-Yeon SY; Kim, Min-Kyeong MK; Kim, Kyung-Sup KS; Hur, Man-Wook MW

Publication Date: 2019-08-30

Variant appearance in text: p53: K382Q

PubMed Link: 31296660

Variant Present in the following documents:

• Main text

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Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity.

Nature Communications

Loffreda, Alessia A; Jacchetti, Emanuela E; Antunes, Sofia S; Rainone, Paolo P; Daniele, Tiziana T; Morisaki, Tatsuya T; Bianchi, Marco E ME; Tacchetti, Carlo C; Mazza, Davide D

Publication Date: 2017-08-22

Variant appearance in text: p53: K382Q

PubMed Link: 28827596

Variant Present in the following documents:

• Main text
• 41467_2017_Article_398.pdf
• 41467_2017_398_MOESM9_ESM.pdf

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: K382Q

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.

Nature Communications

Johmura, Yoshikazu Y; Sun, Jia J; Kitagawa, Kyoko K; Nakanishi, Keiko K; Kuno, Toshiya T; Naiki-Ito, Aya A; Sawada, Yumi Y; Miyamoto, Tomomi T; Okabe, Atsushi A; Aburatani, Hiroyuki H; Li, ShengFan S; Miyoshi, Ichiro I; Takahashi, Satoru S; Kitagawa, Masatoshi M; Nakanishi, Makoto M

Publication Date: 2016-02-12

Variant appearance in text: p53: K382Q

PubMed Link: 26868148

Variant Present in the following documents:

• ncomms10574.pdf

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The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.

Molecular Cell

Laptenko, Oleg O; Shiff, Idit I; Freed-Pastor, Will W; Zupnick, Andrew A; Mattia, Melissa M; Freulich, Ella E; Shamir, Inbal I; Kadouri, Noam N; Kahan, Tamar T; Manfredi, James J; Simon, Itamar I; Prives, Carol C

Publication Date: 2015-03-19

Variant appearance in text: p53: K382Q

PubMed Link: 25794615

Variant Present in the following documents:

• Main text

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KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Koh, Dong-In DI; Han, Dohyun D; Ryu, Hoon H; Choi, Won-Il WI; Jeon, Bu-Nam BN; Kim, Min-Kyeong MK; Kim, Youngsoo Y; Kim, Jin Young JY; Parry, Lee L; Clarke, Alan R AR; Reynolds, Albert B AB; Hur, Man-Wook MW

Publication Date: 2014-10-21

Variant appearance in text: p53: K382Q

PubMed Link: 25288747

Variant Present in the following documents:

• Main text

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The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption.

The Journal Of Biological Chemistry

Ono, Wakana W; Hayashi, Yuki Y; Yokoyama, Wataru W; Kuroda, Takao T; Kishimoto, Hiroyuki H; Ito, Ichiaki I; Kimura, Keiji K; Akaogi, Kensuke K; Waku, Tsuyoshi T; Yanagisawa, Junn J

Publication Date: 2014-02-21

Variant appearance in text: p53: K382Q

PubMed Link: 24375404

Variant Present in the following documents:

• Main text

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Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Brochier, Camille C; Dennis, Gretel G; Rivieccio, Mark A MA; McLaughlin, Kathryn K; Coppola, Giovanni G; Ratan, Rajiv R RR; Langley, Brett B

Publication Date: 2013-05-15

Variant appearance in text: p53: K382Q

PubMed Link: 23678107

Variant Present in the following documents:

• Main text

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